Carbohydrates
Medchemexpress LLC 5-bromo-4-chloro-3-indolyl β-D-glucuronide sodium salt | 129541-41-9 | MFCD00135782 | 98.0% | 444.59 g/mol | C14H12BrClNNaO7 | 10 MG
X-Gluc sodium is the sodium salt of 5-bromo-4-chloro-3-indolyl β-D-glucuronide, a chromogenic substrate used to detect β-glucuronidase (GUS) activity. It reacts with GUS to produce an intense blue color and is commonly used in microbiology and molecular biology assays.
- Chromogenic substrate for β-glucuronidase detection
- Produces intense blue color upon enzymatic hydrolysis
- Suitable for bacterial contamination testing and GUS reporter assays
- High purity (98.0%) for reliable experimental results
- Sodium salt form improves handling and aqueous solubility
Medchemexpress LLC Integrin alpha 5 beta 1 protein, human (biotinylated, HEK293, His-Avi) | 95.0% | 50UG
Biotinylated human integrin alpha 5 beta 1 is a recombinantly produced heterodimer expressed in HEK293 cells and supplied as a lyophilized powder with Avi and 8xHis tags. The protein is glycosylated (approx. 110-140 kDa), of high purity, and formulated with trehalose to preserve activity for binding assays and assay development.
- Lyophilized, stable formulation for long-term storage.
- Biotinylated for immobilization on streptavidin surfaces.
- Expressed in mammalian cells to preserve native glycosylation.
- C-terminal Avi and 8xHis tags for detection and purification.
- High purity as determined by SDS-PAGE (>95%).
- Low endotoxin level (<1 EU/μg) suitable for sensitive assays.
- Provided with certificate of analysis and safety data sheet.
- Reconstitute to at least 100 μg/mL in ddH2O for optimal performance.
Medchemexpress LLC SN-38 glucuronide | 121080-63-5 | 99.5% | 568.53 | 1 MG
SN-38 glucuronide, also known as SN-38G, is an inactive metabolite of the anticancer molecule Irinotecan. It has known toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor used in research for colon and rectal cancer. SN-38 glucuronide can be reactivated by gut microbial β-glucuronidase enzymes, which remove the glucuronic acid moiety, thus increasing its toxic effects on the intestine.
- Inactive metabolite of Irinotecan.
- Has toxic effects on the gastrointestinal tract.
- Can be reactivated by gut microbial β-glucuronidase enzymes.
- Relevant in the study of colon and rectal cancer.
- Cells metabolizing SN38 to SN38-G show increased resistance to extracellular SN38.
Medchemexpress LLC Azido-PEG4-beta-D-glucose | 1609083-15-9 | 99.9% | 381.38 | 25 MG
Azido-PEG4-beta-D-glucose is a PEG-based PROTAC linker that facilitates the synthesis of PROTACs. This click chemistry reagent contains an Azide group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an azide functional group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC)
- Intended for research use only
Medchemexpress LLC BSJ-04-122 | 2513289-74-0 | 99.9% | 313.74 g/mol | C15H12ClN5O | 10 MG
BSJ-04-122 is a covalent dual inhibitor of the MAP kinase kinases MKK4 and MKK7 developed for research use. It demonstrates potent enzymatic inhibition (IC50 4 nM for MKK4; 181 nM for MKK7) and is applied in studies of cancer biology and MAPK signaling. The compound is supplied as a solid with high chemical purity and recommended storage conditions for both powder and solution forms.
![eMolecules 1181458-38-7 | 2-AZABICYCLO[3.1.0]HEXANE-5-CARBOXYLIC ACID HCL | AstaTech | MFCD11858205 | 163.600 | C6H10ClNO2 | 95.000 | Cl.OC(=O)C12CC1NCC2 | 1g | 323623522](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502172035.JPG-250.jpg)
eMolecules 1181458-38-7 | 2-AZABICYCLO[3.1.0]HEXANE-5-CARBOXYLIC ACID HCL | AstaTech | MFCD11858205 | 163.600 | C6H10ClNO2 | 95.000 | Cl.OC(=O)C12CC1NCC2 | 1g | 323623522
2-AZABICYCLO[3.1.0]HEXANE-5-CARBOXYLIC ACID HCL | AstaTech | 1181458-38-7 | MFCD11858205 | 163.600 | C6H10ClNO2 | 95.000 | Cl.OC(=O)C12CC1NCC2 | 1g | 323623522
AURUM PHARMATECH INC CYANO-3-AZABICYCLO(3.1.0)H, 1G
Aurum Pharmatech | Cyano-3-azabicyclo[3.1.0]hexane | 1g | Q-3151 | Purity: 95.00% | 115182-91-7 | MFCD19218073 | MW: 108.14
Medchemexpress LLC Neuraminic acid, N-(2-hydroxyacetyl)- | 1113-83-3 | 99.8% | 1 ML
N-Glycolylneuraminic acid, with chemical formula C11H19NO10 and molecular weight 325.27, is a nonhuman sialic acid molecule. Synthesized in pigs but not in humans, it functions as a decoy receptor for N-Glycolylneuraminic acid-binding influenza A viruses (IAVs). This product is supplied as a white to off-white powder with a purity of 99.76% confirmed by HPLC analysis.
- Nonhuman sialic acid molecule
- Synthesized in pigs
- Functions as a decoy receptor for influenza A viruses
- High purity (99.76% by HPLC)
- Provided as a powder
- Chemical formula C11H19NO10
- Molecular weight 325.27
- CAS number 1113-83-3
eMolecules 1113-83-3 | N-Glycolylneuraminic acid | Chem-Impex325.270 | C11H19NO10 | 97.000 | OCC(O)C(O)C1OC(O)(CC(O)C1NC(=O)CO)C(O)=O | 250mg | 386904437
N-Glycolylneuraminic acid | Chem-Impex | 1113-83-3325.270 | C11H19NO10 | 97.000 | OCC(O)C(O)C1OC(O)(CC(O)C1NC(=O)CO)C(O)=O | 250mg | 386904437
![Alkali Scientific NANA [n Acetylneuraminic acid, Synthetic Sialic Acid], 100 Mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661438.jpg-250.jpg)
Alkali Scientific NANA [n Acetylneuraminic acid, Synthetic Sialic Acid], 100 Mg
N-Acetylneuraminic acid (NANA), or synthetic sialic acid, is a vital biochemical reagent used in a wide range of biochemical research applications. This 100mg formulation is ideal for studies on glycosylation and glycoprotein structure, especially in relation to sialic acid’s role in cellular communication, immunity, and infection processes. NANA is commonly used in the synthesis of glycoproteins and glycolipids, and for examining cellular interactions at the molecular level. It is also a key component in the study of enzymes involved in glycan metabolism, and is utilized in both basic research and applied fields like drug discovery and diagnostic assays.
Medchemexpress LLC 4-Methylumbelliferyl palmitate | 17695-48-6 | 99.2% | 414.59 | 10 MG
4-Methylumbelliferyl palmitate is an excellent fluorophore for measuring acid lipase in human leukocytes. Acidity and solvent have important influence on its fluorescence. It exists mainly as neutral molecular form which can be produced strong fluorescence at 445 nm in near neutral aqueous solutions, and exists mainly as anion form which can be produced stronger fluorescence at 445 nm in weak alkaline solutions.
- Excellent fluorophore for measuring acid lipase in human leukocytes.
- Fluorescence is influenced by acidity and solvent.
- Produces strong fluorescence at 445 nm in near neutral aqueous solutions.
- Produces stronger fluorescence at 445 nm in weak alkaline solutions.
![Alkali Scientific MUG [4 Methylumbelliferyl β D glucuronide Trihydrate], 250 Mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660064.jpg-250.jpg)
Alkali Scientific MUG [4 Methylumbelliferyl β D glucuronide Trihydrate], 250 Mg
Methylumbelliferyl β-D Glucuronide Trihydrate, 250 mg is a high-sensitivity biochemical reagent used to study glucuronidase enzyme activity. This fluorogenic substrate is hydrolyzed by glucuronidases, releasing a fluorescent signal that can be measured in enzyme assays. It is widely used in clinical diagnostics, microbiological analysis, and biochemical research to investigate enzyme activity and metabolic pathways. The reagent’s high purity and sensitivity make it suitable for accurate detection of low-level enzyme activity, enabling precise measurements in applications such as genetic studies, microbial enzyme analysis, and diagnostic testing for metabolic conditions.
Medchemexpress LLC 6-(2-(2,4-Difluorophenoxy)-5-((ethylsulfonyl)methyl)pyridin-3-yl)-8-methylpyrrolo[1,2-a]pyrazin-1(2H)-one | 2411226-02-1 | 99.7% | 10 MM * 1 ML
BET bromodomain inhibitor 1 is an orally active, selective bromodomain and extra-terminal (BET) bromodomain inhibitor with an IC50 of 2.6 nM for BRD4. It binds to BRD2(2), BRD3(2), BRD4(1), BRD4(2), and BRDT(2) with high affinities (Kd values of 1.3 nM, 1.0 nM, 3.0 nM, 1.6 nM, 2.1 nM, respectively). This inhibitor also demonstrates anti-cancer activity.
- Orally active, selective bromodomain and extra-terminal (BET) bromodomain inhibitor.
- Binds to BRD2(2), BRD3(2), BRD4(1), BRD4(2), and BRDT(2) with high affinities.
- Exhibits anti-cancer activity.
- Demonstrates antiproliferative activity against various human leukemia and myeloma cell lines.
- Induces G1-phase cell cycle arrest and reduces c-Myc, BCL-2, and CDK6 expressions in MV-4-11 cells.
- Offers high selectivity for the BET bromodomain family.
- Shows strong antitumor activities in an MV4-11 mouse xenograft model.
Medchemexpress LLC IFN-beta Rhesus Mac 10ug
IFN-beta Protein is an immunomodulatory cytokine of the type 1 interferon family IFN-beta Protein reduces joint inflammation by inhibiting the RANKL-c-Fos signaling pathway IFN-beta Protein regulates mitochondrial fission through STAT5 PGAM5 and Drp1 to rescue neurodegeneration IFN-beta Protein Rhesus Macaque (HEK293 Fc) is the recombinant Rhesus Macaque-derived IFN-beta protein expressed by HEK293 with C-mFc labeled tag
Medchemexpress LLC 4-methylumbelliferyl α-D-galactopyranoside | 38597-12-5 | MFCD00063278 | >98.0% | 338.31 g·mol⁻¹ | C16H18O8 | 100 MG
4-Methylumbelliferyl-α-D-galactopyranoside is a fluorogenic substrate for α-galactosidase enzymes. Hydrolysis liberates 4-methylumbelliferone, a fluorescent reporter used to quantify enzyme activity in biochemical assays and diagnostics. Supplied as a solid for laboratory use.
- High purity (≥98%) suitable for enzymatic assays.
- Generates a fluorescent product with emission maximum ~445-454 nm.
- pH-dependent excitation maxima for flexible assay conditions (≈330-385 nm).
- Solid form for straightforward handling and storage.
- Suitable for α-galactosidase activity measurements and diagnostic workflows.