Carbohydrates
Medchemexpress LLC 3-Deazaadenosine hydrochloride | 86583-19-9 | 99.67% | 302.72 | 5 MG
3-Deazaadenosine hydrochloride | 86583-19-9 | 99.67% | 302.72 | 5 MG
Medchemexpress LLC 3-Deazaadenosine | 6736-58-9 | ≥99.0% | 266.26 | 1 MG
3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase (SAHH), with a Ki of 3.9 μM. It exhibits anti-inflammatory, anti-proliferative, and anti-HIV activities.
- Inhibitor of S-adenosylhomocysteine hydrolase (SAHH)
- Anti-inflammatory activity
- Anti-proliferative activity
- Anti-HIV activity
Medchemexpress LLC 6-Azauridine triphosphate ammonium | C8H17N4O15P3 | 1 MG
6-Azauridine triphosphate ammonium is a nucleotide analog similar to uridine triphosphate. It is used to study the mechanism of RNA synthesis and transcription regulation.
- Purity of 95.0%
- Appears as a solid
- Color is white to off-white
- Soluble in H2O at 250 mg/mL (497.85 mM; requires ultrasonic)
Medchemexpress LLC 3-Deazaadenosine hydrochloride | 86583-19-9 | 99.7% | 302.72 | 1 ML
3-Deazaadenosine hydrochloride is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 μM. It exhibits anti-inflammatory, anti-proliferative, and anti-HIV activity. This product is for research use only and not sold to patients.
- Inhibits S-adenosylhomocysteine hydrolase
- Shows anti-HIV effect
- Inhibits LPS-induced expression of TNF-α mRNA
- Enhances nuclear translocation of NF-κB
- Suppresses vascular smooth muscle cell (VSMC) proliferation
Apexbio Technology LLC 3-Deazaadenosine(Synonyms: 3-Deazaadenosine, 3-Deaza-adenosine, 3DA, Cordycepin analog, Tubercidin), 5mg, CAS: 6736-58-9.
3-Deazaadenosine (CAS 6736-58-9) is an inhibitor of S-adenosylhomocysteine (SAH) hydrolase an enzyme responsible for the reversible hydrolysis of SAH into adenosine and homocysteine Inhibition of SAH hydrolase by 3-Deazaadenosine (Ki 3 9 M) elevates intracellular SAH concentrations altering the SAH-to-SAM (S-adenosylmethionine) ratio and consequently suppressing SAM-dependent methyltransferase activities In vitro studies demonstrate its antiviral activity against Ebola and Marburg viruses in various primate and mouse cell lines Animal studies indicate protective efficacy against lethal Ebola infection in BALB/c mice Currently 3-Deazaadenosine remains in preclinical research
Apexbio Technology LLC 5-Azacytidine 320-67-2 1g
5-Azacytidine is a cytidine analog compound that functions as an inhibitor of DNA methyltransferase (DNMT) Its mechanism involves incorporation into cellular DNA/RNA followed by covalent binding to DNMT through the formation of a bond between the C6 position of 5-Azacytidine and the thiol group of cysteine residues in DNMT enzymes leading to reduced DNMT activity and subsequent DNA demethylation In cellular studies involving multiple myeloma (MM) 5-Azacytidine exhibits cytotoxicity against MM-derived cell lines (MM 1S MM 1R RPMI-8266 RPMI-LR5 RPMI-Dox40) with reported IC50 values of approximately 1 5 mol/L 0 7 mol/L 1 1 mol/L 2 5 mol/L and 3 2 mol/L respectively as well as patient-derived MM cells (IC50 1 5 mol/L) This compound is widely used in cancer research to investigate epigenetic regulation mechanisms and DNA methylation pathways
Medchemexpress LLC 8-Azaadenosine 10Mm In 1Ml Dms | HY-115686-10MM/1ML
8-Azaadenosine 10Mm In 1Ml Dms
Apexbio Technology LLC 3-Deazaadenosine hydrochloride(Synonyms: 3-Deazaadenosine HCl, C3-Deazaadenosine hydrochloride, 3-Deaza-adenosine hydrochloride), 1mg, CAS: 86583-19-9.
3-Deazaadenosine hydrochloride (CAS 86583-19-9) is a selective inhibitor of S-adenosylhomocysteine hydrolase (SAHH) exhibiting inhibition with a Ki value around 3 9 M It disrupts SAHH-dependent methyl metabolism pathways thereby altering intracellular methyltransferase reactions Due to this biochemical activity it serves as a research agent for studying inflammation cell proliferation and HIV infection as well as investigations into enzyme-mediated methylation processes and related pathological mechanisms
Apexbio Technology LLC 3-Deazaadenosine hydrochloride(Synonyms: 3-Deazaadenosine HCl, C3-Deazaadenosine hydrochloride, 3-Deaza-adenosine hydrochloride), 10mg, CAS: 86583-19-9.
3-Deazaadenosine hydrochloride (CAS 86583-19-9) is a selective inhibitor of S-adenosylhomocysteine hydrolase (SAHH) exhibiting inhibition with a Ki value around 3 9 M It disrupts SAHH-dependent methyl metabolism pathways thereby altering intracellular methyltransferase reactions Due to this biochemical activity it serves as a research agent for studying inflammation cell proliferation and HIV infection as well as investigations into enzyme-mediated methylation processes and related pathological mechanisms
Medchemexpress LLC IKB beta/NFKBIB Hum 100ug | 100ug
IKB beta/NFKBIB protein effectively inhibits NF-kappa-B and prevents NF-kappa-B activation by forming a cytoplasmic complex After cell stimulation the non-phosphorylated form is resynthesized binds to NF-kappa-B aids nuclear transport and protects NF-kappa-B from NFKBIA-dependent inactivation IKB beta/NFKBIB Protein Human (His) is the recombinant human-derived IKB beta/NFKBIB protein expressed by E coli with N-6 His labeled tag
Medchemexpress LLC Etiocholanolone glucuronide (Etio-G) | 3602-09-3 | 98.0% | 466.56 | 1 MG
Etiocholanolone glucuronide (Etio-G) is a metabolite of Etiocholanolone that is generated in the liver by UDP glucuonyltransferase. This compound is promising for research of metabolic-related diseases. For research use only, this product is not sold to patients.
- Metabolite of etiocholanolone
- Generated in the liver by UDP glucuonyltransferase
- Promising for research of metabolic-related diseases
- Appears as a solid
- Color is white to off-white
- Synonym: Etio-G
- Chemical formula: C25H38O8
- Powder storage: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Epoetin beta | 122312-54-3 | ≥95.0% | 60 kDa | 5000 U
Epoetin beta (rhEPO) is a recombinant form of erythropoietin. It is responsible for the maintenance of erythropoiesis and can be used for anaemia research. It is for research use only and not sold to patients.
- Prevents anaemia and enhances the radiosensitivity of solid growing DS-sarcomas in animal models.
Sigma Aldrich Fine Chemicals Biosciences Salicin European Pharmacopoeia (EP) Reference Standard | 138-52-3 | MFCD00006590 |
Salicin European Pharmacopoeia (EP) Reference Standard | Mol Wt: 286.28 | 138-52-3 | MFCD00006590 |
Medchemexpress LLC 2,4(1H,3H)-Pyrimidinedione, 1-β-D-arabinofuranosyl- | 3083-77-0 | 500 MG
1-beta-D-Arabinofuranosyluracil, also known as Uracil 1-β-D-arabinofuranoside, is a methoxyadenosine derivative isolated from the Caribbean sponge *Tectitethya crypta*. This compound exhibits a diverse bioactivity profile, including anti-inflammatory, analgesic, and vasodilation properties. It also reduces the proliferation of mouse lymphoma cells and inhibits RNA-directed DNA polymerases in L5178Y cells.
- Anti-inflammatory activity
- Analgesic properties
- Vasodilation properties
- Reduces proliferation of mouse lymphoma cells.
- Inhibits RNA-directed DNA polymerases in L5178Y cells.