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Various organic compounds consisting of carbon, hydrogen, and oxygen atoms that are found in foods and living tissues; typically broken down to release energy; includes sugars, sugar alcohols, sugar acids and derivatives, glycosyl compounds, and more.
Heparin Sepharose(R) 6 Fast Flow is a well established BioProcess affinity medium designed for capture or intermediate purification steps. This medium is extensively used for industrial purification of several marketed plasma proteins.Heparin Sepharose(R) 6 Fast Flow is a member of the Cytiva range of affinity chromatography media for capture and intermediate purification.Heparin Sepharose(R) 6 Fast Flow is composed of cross-linked 6% agarose beads modified sodium heparin. Immobilization is performed using chemically stable and oriented coupling giving high binding capacity. The chemical stability of the media is solely dictated by the heparin ligand.This medium allows for fast and reliable separations of biomolecules with an affinity for heparin including antithrombin III coagulation factors and other plasma proteins. Additional applications include DNA binding proteins lipoproteins protein synthesis factors enzymes that act on nucleic acids and steroid receptors.Heparin Sepharo
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CYC-116 is a small-molecule inhibitor of Aurora A and Aurora B kinases with low-nanomolar inhibitory potency. It is used as a research reagent to investigate mitotic signaling and cell-cycle regulation and is supplied as a purified solid for in vitro studies.
Potent dual Aurora A and B inhibitor with Ki ≈8-9 nM.
Suitable for studying mitotic signaling and cell-cycle regulation in vitro.
High purity (>99.0%) for reliable experimental results.
Chemical formula C18H20N6OS; molecular weight 368.46 g·mol⁻¹.
Available in multiple small-quantity pack sizes for laboratory use.
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Aurachin D is an antibiotic that inhibits Gram-positive bacteria and certain fungi by blocking NADH oxidation in beef heart submitochondrial particles. It is for research use only.
Inhibits Gram-positive bacteria and certain fungi
Blocks NADH oxidation
Purity: 99.62%
Formula: C25H33NO
Molecular weight: 363.54
Appearance: Solid
Melting/freezing point: 245°C
Stable under recommended storage conditions
Incompatible with strong acids/alkalis, strong oxidizing/reducing agents
Recommended storage for powder: -20°C for 3 years
Recommended storage for in solvent: -80°C for 6 months, -20°C for 1 month
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DCP-LA is a linoleic acid derivative that selectively and directly activates PKCε. It also activates Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) and inhibits protein phosphatase-1 (PP-1) to stimulate AMPA receptor exocytosis. Additionally, DCP-LA inhibits the activation of caspase-3/-9 and helps protect neurons from oxidative stress-induced apoptosis.
Selectively and directly activates PKCε
Activates Ca(2+)/calmodulin-dependent protein kinase II (CaMKII)
Inhibits protein phosphatase-1 (PP-1)
Stimulates AMPA receptor exocytosis
Inhibits activation of caspase-3/-9
Helps protect neurons from oxidative stress-induced apoptosis
Facilitates hippocampal synaptic transmission
Exhibits protective effect against ischemic brain damage
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Also available in 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. 4-Methylumbelliferyl-beta-D-xylopyranoside (4-Methylumbelliferyl-beta-D-xyloside) exhibits bursting steady-state kinetics in biological experiments, which supports the conclusion of rapid hydrolysis of the glycosidic bond of the substrate 4-Methylumbelliferyl-beta-D-xylopyranoside 4-Methylumbelliferyl-beta-D-xylopyranoside can be used for beta- xylosidase activity studies. Purity 99.46%
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2,4-D sodium (2,4-Dichlorophenoxyacetate) is a selective herbicide used for the control of broad-leaved weeds. It can induce apoptosis and inhibits DNA and protein synthesis, thereby preventing normal plant growth and development. This product is for research use only.
Selective herbicide for broad-leaved weeds
Induces apoptosis
Inhibits DNA and protein synthesis
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Integrin V beta 3 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 3 Protein Human (HEK293 C-His) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 3 protein expressed by HEK293 with C-10 His labeled tag Integrin alpha V beta 3 Protein Human (HEK293 C-His) has molecular weight of 90 31 110-150 kDa respectively
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D-Thyroxine (D-T4) is an orally active thyroid hormone that inhibits the secretion of TSH. It can inhibit goiter, promote metamorphosis of tadpoles, and influence cholesterol metabolism. D-Thyroxine can be used for the study of hypercholesterolemia. This product is intended for research applications only.
Orally active thyroid hormone
Inhibits the secretion of TSH
Can inhibit goiter
Promotes metamorphosis of tadpoles
Influences cholesterol metabolism
Used for the study of hypercholesterolemia
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CHMFL-PI4K-127 is an orally active, potent, and highly selective PfPI4K (Plasmodium falciparum PI4K kinase) inhibitor with an IC50 of 0.9 nM. It demonstrates potent activity against 3D7 Plasmodium falciparum, with an EC50 of 25.1 nM, and exhibits antimalaria efficacy.
Potent and selective PfPI4K inhibitor.
Exhibits antimalaria efficacy.
Orally active compound.
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D-Glucuronic acid lactone, also known by various synonyms, is an endogenous metabolite and a derivative of glucuronic acid. This compound acts as a foundational reagent for various syntheses, making it suitable for a range of research applications.
Preparation of 1-O-acyl glucuronic acids for the anti-inflammatory agent mL-3000.
Synthesis of optically active glucuronic acids.
Production of long-chain alkyl glucuronides.
Potential utility in research pertaining to reversible cerebral vasoconstriction syndrome (RCVS).
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Methylumbelliferyl β-D-Galactosaminide (1g) is a high-purity biochemical reagent used to measure galactosaminidase activity in enzymatic assays. This compound is commonly used in biochemical research to analyze enzymes involved in carbohydrate metabolism, particularly those acting on galactosamine. The hydrolysis of this substrate produces a fluorescent signal that can be easily detected, making it ideal for sensitive and specific enzyme activity assays. The 1g quantity is suitable for larger-scale experiments and high-throughput screening in research settings focused on enzyme characterization, metabolic processes, and drug development.
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Beta-D-Glucopyranosyl nitromethane is a glycosyl derivative of nitromethane, presented as a salt of a strongly basic anion exchanger in the OH cycle. This chemical is intended for research use only, serving as a laboratory chemical and for the manufacture of substances.
Glycosyl derivative of nitromethane.
Presented as a salt of a strongly basic anion exchanger in the OH cycle.
Suitable for laboratory chemical applications.
Used in the manufacture of substances.
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