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Oleic acid-13C18 is a 13C labeled fatty acid. The disposition of 13C18 -oleic acid following in vivo intravenous and oral administration has been determined by liquid chromatography-mass spectrometry.
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sn-Glycero-3-phosphocholine (CAS 28319-77-9) also known as alpha-GPC or choline alfoscerate is a naturally occurring choline compound found in the brain and mammalian milk It serves as a precursor to acetylcholine a key neurotransmitter involved in cognitive processes by efficiently crossing the blood-brain barrier and supplying choline for neurotransmitter synthesis Preclinical and clinical research has examined its potential to enhance cognitive function particularly in neurodegenerative conditions such as Alzheimer s disease and vascular dementia Clinical studies have reported improved cognitive recovery in post-stroke and dementia patients following alpha-GPC administration supporting its utility in neuropharmacology and cognitive disorder research
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Megestrol Acetate (CAS 595-33-5) is a synthetic progestin utilized to downregulate nuclear and cytoplasmic androgen receptor activity It modulates hormone receptor-mediated processes thereby impacting cellular metabolic and signaling pathways Megestrol Acetate exerts its biological activity primarily by inducing apoptosis and disrupting cell cycle progression In in vitro studies using HepG2 cell lines Megestrol Acetate demonstrates proliferation inhibition with an IC50 value of approximately 260 M Based on these pharmacological properties Megestrol Acetate holds research potential in studies of cancer cachexia hepatocellular carcinoma and the investigation of tumor growth mechanisms
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Acetate gossypol (CAS 12542-36-8) is a polyphenolic compound isolated from the seeds and bark of Gossypium herbaceum L It functions primarily as an inhibitor of anti-apoptotic Bcl-2 family proteins thereby promoting apoptosis in various cancer cell types By disrupting mitochondrial membrane potential and modulating cell survival pathways acetate gossypol has been utilized in studies investigating mechanisms of programmed cell death and antitumor activity This compound is frequently employed as a molecular tool in cancer biology and apoptosis research Store under sealed cool and dry conditions to ensure stability
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This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
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Helenalin acetate is a sesquiterpene lactone research compound that acts as a natural NF-κB inhibitor and a potent C/EBPβ inhibitor with reported anti-inflammatory and anticancer activity. It is supplied as a solid (white to off-white) at high purity for use in biochemical and cell-based studies.
Acts as an NF-κB inhibitor and potent C/EBPβ inhibitor.
Reported anti-inflammatory and anticancer activity.
High purity (99.55%) suitable for research applications.
Supplied in small-mass pack sizes for assay-scale experiments.
Store protected from light at -20°C; in solvent: -80°C (6 months), -20°C (1 month).
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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Linaclotide acetate is a potent and selective guanylate cyclase C agonist, developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation.
Potent and selective guanylate cyclase C agonist.
Developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C).
Developed for the treatment of chronic constipation.
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TL13-112 is a degrader of anaplastic lymphoma kinase (ALK) with an IC50 of 0 60 nM It demonstrates anti-proliferative activity in non-small-cell lung cancer (NSCLC) and anaplastic large cell lymphoma (ALCL) cell lines
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PNC-28 acetate is a peptide derived from the mdm-2-binding domain (residues 17-26) of the p53 protein, incorporating a membrane-crossing-penetratin sequence. This compound is suitable for use in pancreatic cancer research.
Can be used for pancreatic cancer research
Blocks growth of a lethal human pancreatic cancer cell line in vitro
Inhibits BMRPA1. Tuc3 tumor growth in vivo, particularly when delivered directly to the tumor
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L-(-)-Bornyl acetate is supplied as a liquid, primarily used as a laboratory chemical and for the manufacture of substances. This compound is stable under recommended storage conditions.
Appearance as a colorless to light yellow liquid.
Stable under recommended storage conditions.
Container should be kept tightly sealed in a cool, well-ventilated area.
Keep away from direct sunlight and sources of ignition.
Recommended storage for pure form is -20°C for 3 years or 4°C for 2 years.
Recommended storage in solvent is -80°C for 6 months or -20°C for 1 month.
Shipping at room temperature if less than 2 weeks.
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