Lipids and Lipid Derivatives
Medchemexpress LLC Semax acetate | 2828433-33-4 | 99.4% | 873.97 | 50 MG
Semax acetate is a BBB-penetrable adrenocorticotropic hormone-like peptide that forms stable complexes with Cu2+. As an analog of Adrenocorticotropic hormone (ACTH) (4-10), it exhibits immunomodulatory, nootropic, and neuroprotective activities, making it valuable in the research of central nervous system diseases like Alzheimer's and cerebral ischemia.
- BBB-penetrable adrenocorticotropic hormone-like peptide
- Forms stable complexes with Cu2+
- Synthetic analog of ACTH (4-10)
- Exhibits immunomodulatory activity
- Possesses nootropic properties
- Offers neuroprotective benefits
- Useful in central nervous system disease research
Cambridge Isotope Laboratories Mono-n-octyl phthalate (ring-1 2-13C2 dicarboxyl-13C2 99%) 100 ug/mL in MTBE 1 2 mL
Mono-n-octyl phthalate (ring-1 2-13C2 dicarboxyl-13C2 99%) 100 ug/mL in MTBE 1 2 mL
Medchemexpress LLC AKN-028 acetate | 98.38% | 362.39 | 1 ML
AKN-028 acetate is a novel, potent, and orally active tyrosine kinase (TK) inhibitor. It specifically targets FMS-like receptor tyrosine kinase 3 (FLT3) with an IC50 value of 6 nM. This compound inhibits FLT3 autophosphorylation and induces a dose-dependent cytotoxic response. It also induces apoptosis through the activation of caspase 3, making it suitable for research in acute myeloid leukemia (AML).
- Potent and orally active tyrosine kinase inhibitor.
- Targets FLT3 with high specificity (IC50 = 6 nM).
- Induces dose-dependent cytotoxic response.
- Activates caspase 3, leading to apoptosis.
- Useful for acute myeloid leukemia (AML) research.
Medchemexpress LLC Goserelin (acetate) | 145781-92-6 | 99.9% | 1329.46 | 50 MG
Goserelin acetate (ICI-118630 acetate) is a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH) that acts as a GnRH agonist. It can be used for the research of breast cancer, epithelial ovarian cancer, and prostate cancer.
- Promotes EOC cell apoptosis at concentrations of 1 nM-1 mM over 48-72 hours.
- Regulates expression of human apoptosis-related genes in SKOV3-ip cells at 100 μM over 24-72 hours.
- Induces EOC cell apoptosis by upregulating FOXO1 through the PI3K/AKT signaling pathway at 100 μM over 24-72 hours.
- Significantly increases the proportion of apoptotic cells in subcutaneous xenograft tumors in vivo.
Medchemexpress LLC Roxatidine Acetate Hydrochloride | 93793-83-0 | 99.6% | 1 ML
Roxatidine Acetate Hydrochloride is a potent, selective, competitive, and orally active histamine H2-receptor antagonist. It has antisecretory potency against gastric acid secretion and can suppress inflammatory responses. This product can be used for gastric and duodenal ulcers research and exhibits antitumor activity.
- Potent, selective, competitive, and orally active histamine H2-receptor antagonist
- Exhibits antisecretory potency against gastric acid secretion
- Can suppress inflammatory responses
- Suitable for gastric and duodenal ulcers research
- Shows antitumor activity
Selleck Chemical LLC TL13-112-E1846-25MG
TL13-112 is a degrader of anaplastic lymphoma kinase (ALK) with an IC50 of 0 60 nM It demonstrates anti-proliferative activity in non-small-cell lung cancer (NSCLC) and anaplastic large cell lymphoma (ALCL) cell lines
Medchemexpress LLC Octyl-a-ketoglutarat 5mg | 876150-14-0 | 5 MG
Octyl-α-ketoglutarate is a cell-permeable ester of α-ketoglutarate used in biochemical and cellular research to modulate HIF signaling and prolyl hydroxylase activity. It is used to probe metabolism, demethylation, and TCA cycle dysfunction in cell-based assays.
- Cell-permeable ester of α-ketoglutarate suitable for cell-based assays.
- Stimulates prolyl hydroxylase (PHD) activity and modulates HIF signaling.
- Useful for studies of metabolism, demethylation, and TCA cycle dysfunction.
- Available in small milligram quantities for research use.
- Provided with quality documentation and testing.
Medchemexpress LLC L-Proline, L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-prolylglycyl-, acetate | 2828433-33-4 | 99.4% | 873.97 | 100 MG
Semax acetate is a BBB-penetrable adrenocorticotropic hormone-like peptide that forms stable complexes with Cu2+. It is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) (4-10) and exhibits immunomodulatory, nootropic, and neuroprotective activities. It is used in research for central nervous system diseases such as Alzheimer's disease and cerebral ischemia.
- Reduces Aβ oligomer levels.
- Increases survival and stimulates choline acetyltransferase activity in cholinergic neurons.
- Increases BDNF and NGF levels in glial cells.
- Ameliorates effects in a rat model of focal cerebral ischemia.
- Increases 5-HIAA concentration in hypothalamus and striatum of mice.
- Affects gene expression related to immune and vascular systems in ischemia rats.
Medchemexpress LLC Phenyl acetate | 122-79-2 | 99.7% | 1 ML
Phenyl acetate is an endogenous metabolite and a metabolite of 2-phenylethylamine, found in urine. It plays a role in regulating glutamine metabolism and has been investigated as a potential detection index for certain diseases, including depression. This product is supplied as a high-purity liquid.
- Endogenous metabolite
- Metabolite of 2-phenylethylamine
- Regulates glutamine metabolism
- Potential detection index for diseases like depression
- Can block glutaminolysis in lung cancer cell lines in vitro
- Colorless to light yellow liquid appearance
- High purity of 99.7%
Indofine Chemical 7-AMINO-4-METHYLCOUMARIN, Flavonoid & Coumarins, 26093-31-2, 98+%, 250 mg
7-AMINO-4-METHYLCOUMARIN, Flavonoid & Coumarins, 26093-31-2, 98+%, 250 mg
Medchemexpress LLC L-796778 acetate | 2922280-21-3 | 1MG
L-796778 acetate is a selective agonist of the sst3 receptor In CHO-K1 cells expressing the hsst3 receptor L-796778 acetate is a partial agonist that inhibits Forskolin (HY-15371)-stimulated cAMP production with an IC50 value of 18 nM L-796778 acetate has anticonvulsant effect[1]
Medchemexpress LLC Eugenol acetate | 93-28-7 | MFCD00026191 | 99.8% | 206.24 | C12H14O3 | 250 MG
Eugenol acetate (acetyleugenol) is a high-purity analytical reference standard supplied for research and analytical applications. It is a colorless to light-yellow solid/liquid mixture with molecular formula C12H14O3 and molecular weight 206.24 g/mol. Typical uses include chromatographic and spectrometric method development, compound identification, and biological research.
- High purity suitable for analytical testing and reference use.
- Available in multiple pack sizes, including 250 mg.
- Provided with certificate of analysis and safety data sheet.
- Suitable for chromatographic and spectrometric method development.
- Useful for compound identification and biological assays.
Cell Signaling Technology Phospho-Zyxin (Ser142/143) (D1E8) Rabbit mAb 20 ul
Phospho-Zyxin (Ser142/143) (D1E8) Rabbit mAb 20 ul