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For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
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Linaclotide acetate is a potent and selective guanylate cyclase C agonist, developed to address conditions such as constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation. It functions by activating guanylate cyclase C, which helps to regulate fluid secretion and gastrointestinal transit. This compound is intended for research purposes only and is not sold to patients.
Potent and selective guanylate cyclase C agonist.
Developed for treating constipation-predominant irritable bowel syndrome.
Developed for treating chronic constipation.
Available in various quantities for research needs.
High purity of 98.61% ensures reliable experimental results.
Detailed documentation including data sheet, COA, and SDS is provided.
Solubility information and preparation protocols are available for in vitro and in vivo studies.
Supported by scientific publications.
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Protirelin acetate is a highly conserved neuropeptide that exerts hormonal control of thyroid-stimulating hormone (TSH) levels and neuromodulatory functions. It is intended for research use only.
Highly conserved neuropeptide
Exerts hormonal control of TSH levels
Functions as a neuromodulator
White to off-white solid appearance
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Vitamin D receptor (VDR) protein is the nuclear receptor of calcitriol which translocates to the nucleus after binding vitamin D3 thereby coordinating cellular activities VDR forms a heterodimer with RXR binds to DNA response elements and initiates the transcription of vitamin D3-responsive genes Vitamin D Receptor/VDR Protein Mouse (sf9 His) is the recombinant mouse-derived Vitamin D Receptor/VDR protein expressed by Sf9 insect cells with C-His labeled tag
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Vitamin D receptor (VDR) protein is the nuclear receptor of calcitriol which translocates to the nucleus after binding vitamin D3 thereby coordinating cellular activities VDR forms a heterodimer with RXR binds to DNA response elements and initiates the transcription of vitamin D3-responsive genes Vitamin D Receptor/VDR Protein Mouse (sf9 His) is the recombinant mouse-derived Vitamin D Receptor/VDR protein expressed by Sf9 insect cells with C-His labeled tag
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DALDA acetate is a potent and highly selective μ-opioid receptor agonist with a Ki of 1.69 nM. It exhibits antinociceptive and respiratory effects. This compound carries a net positive charge (3+) at physiological pH, making it hydrophilic and more polar than morphine.
Potent and highly selective μ-opioid receptor agonist
Exhibits antinociceptive and respiratory effects
Hydrophilic and more polar than morphine
Appearance: Solid, white to off-white
Purity: 99.8%
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Also available in 1 mL, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. DL-alpha-tocopherol acetate (Vitamin E acetate) is a vitamin E derivative used as a vitamin E supplement in poultry feed. Purity 98.85%
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Vitamin K1 2,3-epoxide is an inactive metabolite form of Vitamin K1, which is reduced to active vitamin by microsomal epoxide reductase in the vitamin K epoxide cycle. This compound is involved in blood clotting.
Inactive metabolite form of Vitamin K1.
Reduced to active vitamin by microsomal epoxide reductase.
Involved in blood clotting.
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Histrelin acetate is a GnRH analogue and a GnRH Receptor agonist. It works by increasing serum luteinising hormone (LH), follicle stimulating hormone (FSH), and testosterone levels. It is used in the research of prostate cancer and endometriosis.
Stimulates the release of vasopressin (VP) from isolated rat hypothalamo-neurohypophysial explants
Stimulates oxytocin (OT) release from the rat hypothalamo-neurohypophysial system
Rescues circulating LH concentrations in Csfmop/Csfmop mice
Reduces the number of endometrial glands and atrophies the stroma in rabbits
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Vitamin K5 hydrochloride is a photosensitizer and an antimicrobial agent that functions as a specific PKM2 inhibitor. It is suitable for research related to infection and cancer, and can also be used as a preservative for pharmaceuticals, foods, and beverages.
Acts as a specific PKM2 inhibitor
Induces apoptosis in colon 26 cells
Increases antibacterial effects of UVA irradiation against various bacteria
Generates superoxide anion radical and hydroxyl radical
Inhibits cellular glucose consumption and lactate production
Suppresses the proliferation of colon 26 cells
Induces cell apoptosis and increases caspase-3 activity in colon 26 cells
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Macupatide acetate is a glucose-dependent insulinotropic polypeptide (GIP) receptor agonist designed for the research of type 2 diabetes. It works by improving insulin secretion responses and enhancing insulin sensitivity. In comparative studies, Macupatide acetate demonstrated a greater improvement in insulin sensitivity than Dulaglutide, even with similar weight reduction, and combining these agents showed additive effects.
Acts as a GIP receptor agonist.
Improves insulin secretion responses.
Enhances insulin sensitivity.
Potential for research in type 2 diabetes.
Shows superior insulin sensitivity improvement compared to Dulaglutide.
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