Lipids and Lipid Derivatives
Apexbio Technology LLC Mifepristone, 100mg. Cas: 84371-65-3 MFCD: MFCD00867226. Progesterone receptor antagonist
Mifepristone (RU486) is a potent antagonist of progesterone receptor, used as a contraceptive agent. 84371-65-3. MFCD00867226
Apexbio Technology LLC Cyproterone Acetate 427-51-0 250mg
Cyproterone Acetate (CAS 427-51-0) is a small-molecule antagonist targeting the androgen receptor (AR) It is designed to inhibit AR activation thereby suppressing androgen-mediated cellular signaling Cyproterone Acetate exerts its biological activity primarily through competitive binding to AR displacing endogenous androgen ligands and blocking receptor activation and downstream signaling In experimental assays Cyproterone Acetate demonstrates AR inhibition with an IC50 value of approximately 7 1 nM At higher concentrations (EC50 around 4 0 M) it may also exhibit partial agonist activity on the AR pathway Based on these pharmacological properties Cyproterone Acetate holds research potential in studies of androgen-dependent biological processes AR signaling mechanisms and hormone-sensitive pathologies such as prostate cancer or androgen-related metabolic conditions
Medchemexpress LLC Hydrocortisone cypionate | 508-99-6 | 486.64 | 1 ML
Hydrocortisone cypionate | 508-99-6 | 486.64 | 1 ML
Medchemexpress LLC Cortisone | 53-06-5 | 99.3% | 360.44 | 1 ML
Cortisone (17-Hydroxy-11-dehydrocorticosterone) is an oxidized metabolite of Cortisol, a Glucocorticoid. It functions as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in the binding of Glucocorticoid to the Glucocorticoid-receptor at high concentrations, and has been shown to attenuate apoptosis induced by Cortisol in peripheral-blood mononuclear cells (PBMCs) and decrease BCG lesions and tuberculin reactions in rabbits.
- Acts as an immunosuppressant
- Acts as an anti-inflammatory agent
- Attenuates apoptosis
- Decreases BCG lesions and tuberculin reactions
- Targets Glucocorticoid Receptor
- Is an endogenous metabolite
Medchemexpress LLC Hydrocortisone buteprate | 72590-77-3 | 99.3% | 488.6 g/mol | C28H40O7 | 5 MG
Hydrocortisone buteprate is a medium-potency, non-halogenated double-ester corticosteroid supplied as a solid analytical standard for laboratory research and analytical applications. The material is provided in a 5 mg package with high purity and is intended for research use only.
- Solid analytical standard supplied as a 5 mg package.
- High purity (99.3%).
- CAS number 72590-77-3.
- Chemical formula C28H40O7; molecular weight 488.6 g/mol.
- Used for corticosteroid research and topical formulation studies.
- Not for human or veterinary use; for laboratory research only.
Apexbio Technology LLC Dexamethasone acetate 1177-87-3 5g
Dexamethasone acetate a synthetic glucocorticoid acts by binding to glucocorticoid receptors influencing gene transcription to suppress inflammatory and immune responses By modulating cytokine production and inhibiting interleukin (IL) signaling pathways dexamethasone acetate serves as an interleukin receptor modulator Typically applied in research related to inflammation autoimmune diseases and cytokine-mediated cellular events it is extensively utilized in functional assays to understand receptor-ligand interactions signal transduction and therapeutic mechanisms Studies report variable IC50 values depending on cell type and assay conditions with typical IC50 ranges documented from 1-10 nM in receptor binding assays providing a reference concentration range for experimental designs
Apexbio Technology LLC Cortisone acetate 50-04-4 10mM (in 1mL DMSO)
Cortisone acetate (50-04-4) is a glucocorticoid receptor agonist targeting the glucocorticoid receptor It is designed to modulate glucocorticoid signaling thereby regulating gene transcription and downstream immune and inflammatory responses Cortisone acetate exerts its biological activity primarily through enzymatic conversion to cortisol which subsequently activates glucocorticoid receptors to influence cellular stress and inflammatory pathways Based on these pharmacological properties cortisone acetate holds research potential in the investigation of glucocorticoid signaling pathways receptor-mediated transcriptional regulation cellular stress responses and inflammatory condition models
Medchemexpress LLC Hydrocortisone phosphate sodium | 6000-74-4 | MFCD00152562 | 99.1% | 486.40 g·mol⁻¹ | C21H29Na2O8P | 50 MG
Hydrocortisone phosphate sodium is the disodium phosphate salt of hydrocortisone, a water-soluble corticosteroid used as a research reagent. It has corticosteroid activity with relatively low anti-inflammatory potency and a short duration of action, and is used in biochemical and pharmacological studies, including research on ocular conditions and gastric ulcers.
- Water-soluble sodium phosphate salt suitable for aqueous formulations.
- Useful for biochemical and pharmacological research of corticosteroid activity.
- Relatively low anti-inflammatory potency with short duration of action.
- High purity and defined molecular weight for reproducible results.
- Stable when stored sealed and away from moisture; follow cold storage recommendations for solutions.
Medchemexpress LLC Hydrocortisone sodium phosphate | 6000-74-4 | MFCD00152562 | 99.1% | 486.40 g/mol | C21H29Na2O8P | 25 MG
Hydrocortisone sodium phosphate is the sodium phosphate ester of hydrocortisone, a water-soluble corticosteroid with glucocorticoid anti-inflammatory activity and a short duration of action. It is supplied as a solid research reagent for biochemical and pharmacological studies; consult the safety data sheet for handling and storage.
- Water-soluble sodium phosphate ester of hydrocortisone.
- Provides glucocorticoid anti-inflammatory activity with short duration of action.
- High reported purity supports analytical and biological experiments.
- Suitable for in vitro and in vivo research applications.
- Packaged as a 25 mg solid for convenient small-scale use.