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O-Acetyl-L-carnitine (Acetyl-L-carnitine O-acetyl-L-carnitine O-Acetylcarnitine) can be synthesis or is naturally found in healthy humans It could help transport fatty acids into the mitochondrial matrix where fatty acid metabolism occurs
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Propionylcarnitine is metabolized by carnitine acetyltransferase from propionyl-CoA. Increased propionylcarnitine is considered a biomarker of vitamin B12 deficiency. This product is intended for research use only.
Human endogenous metabolite
Protection of beta-thalassaemic erythrocytes from oxidative stress
Increases production of 14CO2 from [1-14C]pyruvate and increases the rate of formation of acetyl carnitine from pyruvate
Allows endothelial cells to maintain functionality and regulatory role on vessel activity for a longer time, and decreases the formation of oxygen reactive species due to xanthine oxidase activity on hypoxanthine
Affects plasma and urine total carnitine concentrations of mice (2 mM/kg; p.o. for 4 weeks)
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A colorimetric lipase and esterase substrate; upon enzymatic hydrolysis, 4-nitrophenol is released which can be quantified by colorimetric detection at 410 nm as a measure of enzyme activity
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Oxoadipic acid (Standard) is an analytical standard intended for research and analytical applications. It is a key metabolite of the essential amino acids tryptophan and lysine.
Analytical standard
Intended for research and analytical applications
Key metabolite of tryptophan and lysine
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Ethyl linoleate (Linoleic Acid ethyl ester) is an orally active unsaturated fatty acid. It inhibits the Akt/GSK3β/β-catenin signaling pathway and the activation of NF-κB. This compound induces heme oxygenase-1 and inhibits tyrosinase, leading to whitening and anti-inflammatory effects. Ethyl linoleate also promotes compound absorption and significantly influences atherosclerosis. It is used in the research of inflammatory diseases and can be utilized in cosmetics.
Orally active unsaturated fatty acid.
Inhibits the Akt/GSK3β/β-catenin signaling pathway and NF-κB activation.
Induces heme oxygenase-1.
Inhibits tyrosinase.
Possesses whitening and anti-inflammatory effects.
Promotes compound absorption.
Has a significant influence on atherosclerosis.
Used in research of inflammatory diseases.
Can be used in cosmetics.
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Monomethyl auristatin E (MMAE) is a highly potent antimitotic compound that exerts cytotoxic effects by inhibiting tubulin polymerization Microtubules play essential roles in various cellular processes including intracellular transport cell migration and mitotic chromosome segregation MMAE interrupts this process leading to cell cycle arrest and apoptosis MMAE is commonly utilized in preclinical and clinical studies as the cytotoxic payload in antibody-drug conjugates (ADCs) targeting tumor-specific antigens to selectively deliver cytotoxicity to cancer cells In vitro cell studies and in vivo tumor xenograft models show that antibody conjugation enables specific targeting resulting in reduced off-target toxicity and improved therapeutic index compared to unconjugated cytotoxic agents
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A hydroxy fatty acid; a partial agonist of FFAR1/GPR40 and GPR85 receptors in vitro (EC50s = 6.7 and 12.8 μM, respectively); inhibits bovine hepatic ligase (Ki = 4.4 μM); inhibits medium-chain acyl-CoA synthetase by 48% in mouse kidney mitochondria (40 μM)
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