Lipids and Lipid Derivatives
Medchemexpress LLC (R)-(-)-Ibuprofen-d3 | 121702-86-1 | 100.0% | C13H15D3O2 | 1 MG
This deuterium-labeled compound, (R)-(-)-Ibuprofen-d3, serves as the R enantiomer of Ibuprofen. It is inactive on COX and functions as an inhibitor of NF-κB activation, demonstrating anti-inflammatory and antinociceptive effects.
- Can be used as a tracer
- Suitable as an internal standard for quantitative analysis
- Ideal for use in NMR, GC-MS, or LC-MS
Cambridge Isotope Laboratories Ractopamine HCl (1-methyl-D3-propyl-1 2 2-D3 98%) CP 95% 1 mg
Ractopamine HCl (1-methyl-D3-propyl-1 2 2-D3 98%) CP 95% 1 mg
Medchemexpress LLC Ranolazine-d3 | 1054624-77-9 | 99.5% | 25 MG
Ranolazine-d3 is the deuterium labeled version of Ranolazine, an anti-angina agent that inhibits the late phase of inward sodium current (INa) and IKr, with IC50 values of 6 μM and 12 μM, respectively, without impacting heart rate or blood pressure. It also acts as a partial fatty acid oxidation (FAO) inhibitor. This compound is an antianginal agent primarily used for research purposes. Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Selleck Chemical LLC Vitamin A Acetate S4083-50mg
Vitamin A Acetate (Retinyl Retinol) is a group of unsaturated nutritional hydrocarbons that includes retinol retinal retinoic acid and several provitamin A carotenoids among which beta-carotene is the most important
Cambridge Isotope Laboratories 2 6-Dinitrotoluene (methyl-D3 98%) 1 mg/mL in acetonitrile 1 mL
2 6-Dinitrotoluene (methyl-D3 98%) 1 mg/mL in acetonitrile 1 mL
Cambridge Isotope Laboratories 1 25-Dihydroxyvitamin D2 (unlabeled) CP 95% 1 mg
1 25-Dihydroxyvitamin D2 (unlabeled) CP 95% 1 mg
MOLECULAR DEPOT LLC 25-OH Vitamin D3 Biotin - 1 mg
25-OH Vitamin D3 Biotin Conjugate consists of 25-OH Vitamin D3 conjugated to Biotin via a 22 A spacer arm The spacer adds flexibility to the 25-OH Vitamin D3 moiety which is required for its interaction with specific antibodies and other binding partners This compound has been tested for use in several 25-OH Vitamin D applications including ELISA The conjugate is supplied as a DMSO stock solution For in vitro research use only
Medchemexpress LLC Fluorometholone acetate | 3801-06-7 | 98.5% | 50MG
Fluorometholone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It potently inhibits carbonic anhydrase (CA) with IC50s of 2.18 μM and 17.5 μM for hCA-I and hCA-II, respectively. Fluorometholone acetate has an anti-inflammatory effect and has the potential for external ocular inflammation research.
- Synthetic glucocorticoid corticosteroid
- Potent carbonic anhydrase inhibitor
- Exhibits anti-inflammatory effects
- Potential for external ocular inflammation research
Sigma Aldrich Fine Chemicals Biosciences Cortisone 21-Acetate | 50-04-4 | MFCD00003609 | 10g
Cortisone 21-Acetate | Purity: 99% | Mol Wt: 402.48 | 50-04-4 | MFCD00003609 | 10g
Medchemexpress LLC Z-guggulsterone | 39025-23-5 | MFCD01310757 | 99.4% | 312.45 g/mol | C21H28O2 | 5 MG
(Z)-Guggulsterone is a plant-derived sterol (CAS 39025-23-5) isolated from Commiphora mukul. It acts as a farnesoid X receptor (FXR) antagonist with reported activities including induction of apoptosis, inhibition of angiogenesis, and modulation of ACE2 expression, and is used in biochemical and cell-signaling research.
- Potent farnesoid X receptor (FXR) antagonist.
- Induces apoptosis in multiple cancer cell lines.
- Inhibits angiogenesis via the VEGF-VEGFR2-Akt pathway.
- Reported to reduce ACE2 expression and SARS-CoV-2 infection in studies.
- Suitable for biochemical and signaling pathway research applications.
Medchemexpress LLC Estrone (Standard) | 53-16-7 | 99.7% | 50 MG
Estrone (Standard) is the analytical standard of Estrone, a natural estrogenic hormone (E1) produced by various tissues, particularly adipose tissue. It is intended for research and analytical applications, resulting from the aromatization of androstenedione in fat cells.
- Used as a reference standard assay
- Utilized in qualitative, quantitative, and methodological research experiments
- Commonly used in HPLC, GC, and MS applications
Medchemexpress LLC Estrone-13C3 | 1241684-29-6 | 98.0% | 1 MG
Estrone-13C3 is the 13C-labeled version of Estrone, a naturally occurring estrogenic hormone. It is a primary endogenous estrogen, synthesized in various tissues through the aromatization of androstenedione. This compound is suitable for research use as a tracer and as an internal standard for quantitative analysis.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Estradiol-d5 | 221093-45-4 | 99.1% | 1 MG
Estradiol-d5 is a deuterium-labeled form of Estradiol. Estradiol is a steroid sex hormone crucial for maintaining fertility and secondary sexual characteristics in females. It upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS.
- Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules for quantitation during the drug development process.