Solvents
Apexbio Technology LLC GM 6001 142880-36-2 10mM (in 1mL DMSO)
GM 6001 (Ilomastat Galardin CAS 142880-36-2) is a broad-spectrum inhibitor of matrix metalloproteinases (MMPs) including MMP-1 -2 -3 -8 and -9 with reported Ki values of 0 4 nM 0 5 nM 27 nM 0 1 nM and 0 2 nM respectively MMPs participate in extracellular matrix remodeling and mediate signaling events induced by GPCR agonists through EGFR transactivation GM 6001 suppresses EGFR phosphorylation ERK activation and subsequent DNA synthesis induced by stimuli such as bombesin and lysophosphatidic acid (LPA) Additionally this compound has potential applications in cartilage research facilitating meniscal repair under inflammatory conditions by dampening IL-1-mediated MMP activity
Apexbio Technology LLC RG7112 939981-39-2 10mM (in 1mL DMSO)
RG7112 (CAS 939981-39-2) is a selective small-molecule inhibitor of the interaction between the tumor suppressor protein p53 and its negative regulator MDM2 By blocking MDM2-p53 binding RG7112 releases and stabilizes p53 thereby enhancing the transcriptional activation of genes responsible for cell cycle arrest and apoptosis RG7112 preferentially inhibits proliferation in cancer cells harboring wild-type p53 exhibiting IC50 values ranging from 0 18 to 2 2 M whereas its efficacy diminishes significantly in p53-mutant cells RG7112 is used as a tool compound in biomedical research investigating p53-dependent antitumor mechanisms and pathways affecting hematopoiesis
Sigma Aldrich Fine Chemicals Biosciences Toluene suitable for HPLC
Toluene a benzene analog is widely employed as an organic solvent. It has been reported to be a biotoxic solvent (toxic to many microorganisms at 0.1%v/v concentrations). Its anaerobic biodegradation to CO2 by the denitrifying bacterium Thauera arornatica has been reported. It forms syndiotactic polystyrene-toluene molecular compound. Crystal structure of this molecular compound has been investigated by X-ray diffraction studies.
Cayman Chemical PIrlIndole-d4hydrochlorIde 1mg
An internal standard for the quantification of pirlindole by GC- or LC-MS
Cayman Chemical TIclopIdIn-d4hydrochlorIde 1mg
An internal standard for the quantification of ticlopidine by GC- or LC-MS
![eMolecules Synthonix / 3-(hydroxymethyl)-5-iodobenzoic acid / 25mg / 779537145 / AC78211 / / 2386393-03-7 / [null] / 278.045 / C8H7IO3](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502473482.JPG-250.jpg)
eMolecules Synthonix / 3-(hydroxymethyl)-5-iodobenzoic acid / 25mg / 779537145 / AC78211 / / 2386393-03-7 / [null] / 278.045 / C8H7IO3
Synthonix / 3-(hydroxymethyl)-5-iodobenzoic acid / 25mg / 779537145 / AC78211 / / 2386393-03-7 / [null] / 278.045 / C8H7IO3
Sigma Aldrich Fine Chemicals Biosciences N,N-Dimethylformamide ACS reagent, >=99.8% | 68-12-2 | MFCD00003284 | 4X4L
N,N-Dimethylformamide ACS reagent, >=99.8% | Purity: >=99.8% | Mol Wt: 73.09 | 68-12-2 | MFCD00003284 | 4X4L
Cambridge Isotope Laboratories GLYCINE-N-FMOC (2-13C, 99%;15N, 98%), 0.1 G
GLYCINE-N-FMOC (2-13C, 99%;15N, 98%), 0.1 G
Cambridge Isotope Laboratories L-METHIONINE (1-13C, 99%; 15N, 98%), 0.25 G
L-METHIONINE (1-13C, 99%; 15N, 98%), 0.25 G
Cambridge Isotope Laboratories L-TYROSINE (1-13C, 99%; 15N, 98%), 0.25 G
L-TYROSINE (1-13C, 99%; 15N, 98%), 0.25 G
Cambridge Isotope Laboratories L-PHENYLALANINE (13C9, 99%; 15N, 99%), 0.1 G
L-PHENYLALANINE (13C9, 99%; 15N, 99%), 0.1 G