Glycosyl compounds
TARGETMOL CHEMICALS INC Arnicolide D 1MG
Also available in 5 mg, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner. Arnicolide D exerts strong cytotoxic activity on the human colon carcinoma HT-29 cell line. Purity 96.66%
![Medchemexpress LLC [Ala11,D-Leu15]-Orexin B(human) | 532932-99-3 | 98.3% | 2857.26 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000424569.png-250.jpg)
Medchemexpress LLC [Ala11,D-Leu15]-Orexin B(human) | 532932-99-3 | 98.3% | 2857.26 | 5 MG
Ala11, D-Leu15-Orexin B(human) is a potent and selective orexin-2 receptor (OX2) agonist. This peptide demonstrates a 400-fold selectivity for OX2 (EC50=0.13 nM) over OX1 (52 nM), highlighting its specific action on the orexin system. It is provided with a purity of 98.3% and is intended for research use only.
- Potent and selective OX2 agonist.
- High selectivity for OX2 over OX1.
- For research use only.
- High purity.
Medchemexpress LLC Beta-Cortol | 667-65-2 | 99.9% | 368.51 | 1 ML
Beta-Cortol is an O-glycosylated compound and cortisol metabolite, isolated from the leaves of mulberry cultivar Yu 711. Its concentration significantly decreases when the plant is subjected to drought stress. It functions as a biomarker, as serum Beta-Cortol levels in early non-small cell lung cancer models are downregulated to 1/8 of the preoperative level after tumor resection. Due to these notable changes under specific pathological conditions, Beta-Cortol is broadly utilized in studies concerning early non-small cell lung cancer.
- O-glycosylated compound and cortisol metabolite.
- Isolated from the leaves of mulberry cultivar Yu 711.
- Concentration decreases significantly in plants under drought stress.
- Biomarker for early non-small cell lung cancer, with serum levels dropping to 1/8 of preoperative levels after tumor resection.
- Widely used in studies related to early non-small cell lung cancer.
Research Products International Corp p Nitro BD galactopyrano 50G
Colorimetric and spectrophotoametric substrate for detection of B-D Galactosidase.
Medchemexpress LLC Peonidin-3-O-galactoside chloride | 28148-89-2 | 97.1% | 498.86 | 1 MG
Peonidin-3-O-galactoside chloride is an anthocyanin with antioxidant properties. It is intended for research use only.
- Anthocyanin compound
- Possesses antioxidant properties
- For research use only
Research Products International Corp p Nitro a D glucopyrano 50G
Spectrophotometer substrate for Glucansucrases.
Free PNP: <250ppm
Cayman Chemical 6 6-Trehalose DIoleate 1mg
A glycolipid; has been used in the generation of LNPs for the delivery of mRNA in vitro and in vivo; LNPs containing 6,6′-TDO and encapsulating mRNA encoding influenza HA increase Ifn-γ, Il-2, and Tnf-α secretion by isolated mouse splenocytes; LNPs containing 6,6′-TDO accumulate in the liver and spleen after intramuscular administration in mice; unlike LNP formulations that do not contain 6,6′-TDO, LNPs containing 6,6′-TDO do not decrease serum levels of BUN or increase serum levels of LDH, troponin I, ALT, and AST in mice; LNPs containing 6,6′-TDO and encapsulating mRNA encoding influenza A HA increase serum IgG1 and IgG2a titers in mice
Medchemexpress LLC 2,4-D-13C6 (2,4-dichlorophenoxyacetic acid-13C6) | 150907-52-1 | 97.5% | 226.99 | 5 MG
2,4-D-13C6 is the 13C-labeled version of 2,4-D (HY-18572). 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide used for controlling broad-leaved weeds. It functions as a plant hormone, inducing uncontrolled growth in meristematic tissues and inhibiting DNA and protein synthesis, thereby preventing normal plant growth and development.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, primarily as tracers for quantitation during drug development.
Medchemexpress LLC D-(-)-Pantolactone | 599-04-2 | 100.0% | 130.14 | 10 MM * 1 ML
D-(-)-Pantolactone is an important intermediate that can be used in the synthesis of other active compounds, such as the molluscicide Cyanolide A. It is also a calibrant for circular dichroism (CD). Its derivatives show good inhibitory activities against FAS and lipid accumulation, making them potentially useful in the research of anti-obesity drugs.
- Derivatives show good inhibitory activities against FAS and lipid accumulation
- Potentially useful in the research of anti-obesity drugs
Medchemexpress LLC Iwp-o1 | 2074607-48-8 | 99.8% | 432.48 g·mol-1 | C26H20N6O | 10 MG
IWP-O1 is a small-molecule porcupine (PORCN) inhibitor used in research to block Wnt protein secretion and signaling. It demonstrates high potency in cell-based assays and suppresses phosphorylation of downstream signaling proteins, making it useful as a tool compound for Wnt pathway studies.
- Potent porcupine (PORCN) inhibitor; EC50 ~80 pM in L-Wnt-STF cells.
- Inhibits Wnt protein secretion and downstream signaling in cell-based assays.
- Suppresses phosphorylation of Dvl2/3 and LRP6 in HeLa cells.
- High reported purity of 99.8%.
- Molecular formula C26H20N6O; molecular weight 432.48 g·mol-1.
- Store protected from light at 4°C; in solvent, -80°C (6 months) or -20°C (1 month).