Monosaccharides
Medchemexpress LLC USP7 Ligand-Linker Conjugates 1 | 99.9% | 671.83 | 5 MG
USP7 Ligand-Linker Conjugates 1 is a Target Protein Ligand-Linker Conjugate that incorporates a ligand for USP7 and a PROTAC linker, which recruits E3 ligases. It can be used for the synthesis of PROTAC USP7 Degrader-1.
- Target protein ligand-linker conjugates; deubiquitinase
- Protac; cell cycle/DNA damage
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
Medchemexpress LLC Phosphocreatine disodium | 922-32-7 | 98.0% | 1 ML
Phosphocreatine is an organic compound found in vertebrate skeletal muscles. It enhances antioxidant activity, activates the TAK1 pathway to protect the heart, normalizes mitochondrial function, and reduces oxidative stress via the Akt-mediated Nrf2/HO-1 pathway. It also provides renal protection by suppressing Apoptosis and Reactive Oxygen Species (ROS) generation through the ERK-mediated Nrf-2/HO-1 pathway.
- Enhances antioxidant activity.
- Activates the TAK1 pathway to protect the heart.
- Normalizes mitochondrial function.
- Reduces oxidative stress via Akt mediated Nrf2/HO-1 pathway.
- Provides renal protection by suppressing Apoptosis and ROS generation through ERK mediated Nrf-2/HO-1 pathway.
- Human endogenous metabolite.
AdipoGen BQC
Chemical. CAS 207124-63-8. Formula C20H10K2N2O4 . 3H2O. MW 474.55. 2,2´-Biquinoline-4,4´-dicarboxylic acid dipotassium salt BQC is a water soluble biquinoline-based ligand. The oxidation of alcohols to the corresponding aldehydes and ketones, which can be performed by a variety of methods, remains one of the most important reactions in organic synthesis. BOC is used in the aerobic oxidation of alcohols primary, secondary and benzylic in the presence of palladium catalysts. The catalytic system composed of CuCl2 and BQC was found to be highly efficient for the selective oxidation of secondary benzylic, allylic and propargylic alcohols to the corresponding ketones, with aqueous t-butyl hydroperoxide under phase-transfer catalysis conditions. The catalytic system is stable and can be recycled and reused several times without loss of activity.
Apexbio Technology LLC Phosphoramidon Disodium Salt 164204-38-0 10mg
Phosphoramidon Disodium Salt (CAS 164204-38-0) is a metalloproteinase inhibitor targeting metalloenzyme activity implicated in endothelin biology Metalloproteinases rely on metal ions typically zinc for catalytic function Phosphoramidon interferes with the enzymatic conversion of big endothelin-1 (big ET-1) into endothelin-1 (ET-1) thereby decreasing ET-1 secretion while increasing levels of precursor peptides It reduces immunoreactive ET-1 release from porcine aortic endothelial cells and diminishes hypertensive responses triggered by big ET-1 in rodent models As such phosphoramidon serves as a valuable tool compound for cardiovascular and endothelin-related experimental research
Medchemexpress LLC Cromolyn (disodium) | 15826-37-6 | 89.2% | 100 MG
Cromolyn disodium is an analytical standard for research applications. It acts as an orally active GSK-3β inhibitor and a mast cell stabilizer, inhibiting mediator release, regulating bronchoconstriction, and reducing bronchial hyperreactivity. Used in asthma research, it also shows anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects.
- Analytical standard for research
- GSK-3β inhibitor and mast cell stabilizer
- Inhibits mediator release
- Regulates bronchoconstriction
- Reduces bronchial hyperreactivity
- Applied in asthma research
- Anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects
- Suitable for HPLC, GC, and MS
- White to off-white solid
- Stable under recommended storage
Apexbio Technology LLC L-a-Hydroxyglutaric acid disodium salt(Synonyms: Disodium L-alpha-hydroxyglutarate, L-alpha-Hydroxyglutaric acid disodium salt), 50mg, CAS: 63512-50-5.
L-a-Hydroxyglutaric acid disodium salt (CAS 63512-50-5) is a salt derivative of L- -hydroxyglutaric acid a metabolite implicated in the rare condition L- -hydroxyglutaric aciduria due to dysfunction of L-2-hydroxyglutarate dehydrogenase It is employed experimentally to enhance stabilization and recovery yield of hypoxia-inducible factor-1 (HIF-1 ) a recognized indicator of tumor hypoxia Additionally it functions as a research tool in enzymatic assays evaluating modulation of TET family methylcytosine dioxygenases In animal models the compound promotes oxidative stress evidenced by elevated brain chemiluminescence and lipid peroxidation effects mitigated by antioxidant treatments Currently this molecule remains in preclinical investigational stages
Medchemexpress LLC Tripropyl phosphate-d21 | 1219794-92-9 | 98.0% | 245.36 | 25 MG
Tripropyl phosphate-d21 is a deuterium labeled version of Tripropyl phosphate. It is intended for research use only and can be used as a tracer or an internal standard for quantitative analysis. Deuterium substitution has shown potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC IACS-8803 disodium | 2243079-36-7 | 99.97% | 25 MG
IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist that has demonstrated robust systemic antitumor efficacy. Studies show it exhibits superior antitumor activity, particularly via intra-tumoral injection.
- Highly potent cyclic dinucleotide STING agonist
- Demonstrates robust systemic antitumor efficacy
- Exhibits superior antitumor activity via intra-tumoral injection
- Store solid at -20°C under nitrogen, away from moisture
- Store in solvent at -80°C for 6 months or -20°C for 1 month, under nitrogen, away from moisture
![Alkali Scientific EDTA Disodium Salt [Ethylenediaminetetra acetic acid, disodium salt dihydrate], 5 Kg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660361.jpg-250.jpg)
Alkali Scientific EDTA Disodium Salt [Ethylenediaminetetra acetic acid, disodium salt dihydrate], 5 Kg
EDTA Disodium Salt (5 kg) is a large-quantity chelating agent used in laboratories to control metal ion concentrations in samples and experiments. This reagent is highly effective in sequestering metal ions, which can otherwise interfere with chemical reactions, enzymatic processes, or molecular biology techniques. EDTA is commonly used in DNA extractions, protein purifications, and microbiological analyses. Its role in preventing metal-catalyzed reactions makes it indispensable in biochemistry and molecular research. The 5 kg bulk packaging is ideal for laboratories with high demand for EDTA in large-scale experiments, helping researchers manage metal ion interference efficiently.
Medchemexpress LLC K-Ras ligand-Linker Conjugate 6 formate | 98.9% | 25 MG
K-Ras ligand-Linker Conjugate 6 formate is a chemical compound with the molecular formula C43H62N8O9 and a molecular weight of 835.00. This compound is provided in an off-white to light yellow solid form and is suitable for various laboratory applications requiring high purity chemical reagents.
- High purity of 98.93% verified by HPLC
- Appears as an off-white to light yellow solid
- Store at -20°C in sealed conditions, away from moisture
- In solvent, store at -80°C for 6 months or -20°C for 1 month in sealed conditions
- Analytical data (1H NMR spectrum, MS) are consistent with its structure