Sugar acids and derivatives
Cayman Chemical D-GlucuronIc AcId 50g
A metabolite of glucose; a component of proteoglycans; levels are increased in fibroblasts isolated from patients with ISSD or Salla disease
Medchemexpress LLC Rose-β-D-gal | 138182-21-5 | MFCD00467206 | 99.7% | 329.73 g/mol | C14H16ClNO6 | 25 MG
Rose-β-D-Gal is a chromogenic β-galactosidase substrate that produces a pink/magenta color upon enzymatic cleavage. It is used to detect β-gal activity in biochemical and cell-based assays where a visible color change is required.
- Produces a pink/magenta chromogenic signal for β-gal activity detection.
- Suitable for enzymatic assays and staining applications.
- High reported purity (99.71%) for consistent performance.
- Solid reagent supplied in small milligram quantities for research use.
- Compatible with colorimetric readouts and microscopy.
eMolecules Ambeed -D-glucuronide-pNP-carbonate 50mg 847281786 A1365593 0 000 894095-98-8 913 842 C45H43N3O18
Ambeed -D-glucuronide-pNP-carbonate 50mg 847281786 A1365593 0 000 894095-98-8 913 842 C45H43N3O18
BIOHIPPO T-bet-TAG-Puro LV
T-bet-TAG-Puro is a transcription factor reporter lentiviral vector designed to monitor the target signaling pathway in living cells The construct carries a fluorescent reporter gene under the control of pathway responsive elements and includes a puromycin selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures
Medchemexpress LLC 4-Methylumbelliferyl-α-D-Glucopyranoside | 17833-43-1 | 99.99% | 338.31 | 25 MG
4-Methylumbelliferyl-α-D-Glucopyranoside is a fluorescent substrate for α-glucosidase, which releases the fluorescent moiety 4-methylumbelliferyl (4-MU) upon cleavage. 4-MU exhibits pH-dependent fluorescence excitation activity, with excitation wavelengths of 320 nm at low pH (1.97-6.72) and 360 nm at high pH (7.12-10.3). The emission wavelength of 4-Methylumbelliferyl-α-D-Glucopyranoside increases with decreasing pH, ranging from 445-455 nm. This compound can be utilized as a biomarker for Fabry and Pompe diseases to quantify α-glucosidase activity in infant blood spot samples.
- Fluorescent substrate for α-glucosidase.
- Releases fluorescent moiety 4-methylumbelliferyl (4-MU) upon cleavage.
- 4-MU has pH-dependent fluorescence excitation activity.
- Can be used as a biomarker for Fabry and Pompe diseases.
- Quantifies α-glucosidase activity in infant blood spot samples.
Medchemexpress LLC MSX-122 | 897657-95-3 | 98.2% | 292.34 | 25 MG
MSX-122 is an orally active partial antagonist of CXCR4, inhibiting CXCR4/CXCL12 actions, with an IC50 of ~10 nM.
- Anti-inflammatory activity.
- Anti-metastatic activity.
- Orally active.
- Potently blocks invasion of MDA-MB-231 cells in vitro.
- Blocks inflammation induced by carrageenan and lung fibrosis induced by bleomycin in mice.
- Blocks metastasis in an experimental animal model of breast cancer metastasis.
- Significantly decreases the numbers of hepatic micrometastases in vivo.
Medchemexpress LLC Cytochalasin D | 22144-77-0 | 25 MG
Cytochalasin D (Zygosporin A) is a potent, cell-permeable inhibitor of actin polymerization, derived from fungus. It works by binding to G-actin, thereby inhibiting the interaction between G-actin and cofilin. This action also reduces the binding of cofilin to F-actin, consequently decreasing the rate of both actin polymerization and depolymerization in living cells.
- Effectively disrupts the dynamics of actin filaments.
- Can easily enter cells to exert its effects.
- Prevents cofilin from interacting with G-actin.
- Modulates actin dynamics within cells.
- Can lower the amount of survivin in the tumor environment by reducing exosome release.
- Affects the localization and activity of the Yap protein.
Medchemexpress LLC Mac glucuronide linker-1 | 2222981-71-5 | 96.4% | 897.90 g/mol | C42H47N3O17S | 500 MG
MAC glucuronide linker-1 is a cleavable glucuronide-based linker developed for constructing antibody-drug conjugates (ADCs) in research applications. It is supplied as a solid with reported high purity and specific storage recommendations for stability.
- Cleavable glucuronide-based linker suitable for ADC construction.
- Reported purity 96.36% (typical).
- Molecular weight 897.90 g/mol.
- Chemical formula C42H47N3O17S.
- Supplied as a powder; multiple package sizes available.
- Recommended storage: 4°C under nitrogen; in solvent: -80°C (6 months), -20°C (1 month).
- For research use only; not for human therapeutic use.
Medchemexpress LLC Glucuronic acid sodium | 7182-77-6 | 100 MG
Glucuronic acid sodium is a polysaccharide that shows anti-inflammatory activity, aids in the healing of ulcerative colitis, and improves the intestinal barrier by upregulating tight junction proteins like ZO-1 and Occludin. It also helps modulate gut microbiota by increasing beneficial bacterial populations and suppressing harmful ones.
- Exhibits anti-inflammatory activity
- Supports healing of ulcerative colitis
- Enhances intestinal barrier by upregulating tight junction proteins (ZO-1, Occludin)
- Modulates gut microbiota by increasing beneficial bacteria and suppressing harmful ones
Medchemexpress LLC 4-Methylumbelliferyl sulfate potassium | 15220-11-8 | 99.3% | 294.32 | 500 MG
4-Methylumbelliferyl sulfate (potassium) is a fluorescent substrate used to detect sulfatase activity in biochemical and biomedical research. It consists of a sulfate group attached to a fluorescent molecule, which is cleaved by sulfatase enzymes. Upon cleavage, it releases a highly fluorescent product detectable by fluorescence microscopy or spectroscopy. This allows for accurate detection and quantification of these enzymes in various biological samples. It is for research use only and not sold to patients.
- Fluorescent substrate
- Detects sulfatase activity in biochemical and biomedical research
- Releases a highly fluorescent product upon cleavage by sulfatase enzymes
- Allows accurate detection and quantification of sulfatase enzymes in biological samples
Medchemexpress LLC 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside | 37067-30-4 | 100.0% | 379.36 | 50 MG
4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside is a fluorogenic substrate used in N-acetyl-β-D-glucosaminidase research. This compound helps assess enzyme functionality by its ability to remove terminal β-glycosidically bound N-acetylglucosamine and N-acetylgalactosamine residues from the substrate. It is intended for research use only. For optimal preservation, solid material should be stored at 4°C, protected from light. In solvent, store at -80°C for 6 months or -20°C for 1 month, also protected from light.
- Purity: 99.95%
- Molecular weight: 379.36
- Formula: C18H21NO8
- CAS number: 37067-30-4
- Appearance: Solid
- Color: White to off-white
- Assesses enzyme functionality
- Soluble in DMSO (50 mg/mL)
Medchemexpress LLC 1-Propanone, 3-(2,4-dihydroxy-6-methoxyphenyl)-1-(4-hydroxyphenyl)- | 119425-91-1 | 10 MG
Loureirin D is a dihydrochalcone found in dragon's blood. This product is for research use only and has not been fully validated for medical applications.
- Dihydrochalcone found in dragon's blood
- Purity of 99.30%
- Molecular formula: C16H16O5
- Molecular weight: 288.30
- Appears as a white to pink solid
- Store at 4°C, protected from light
- Store in solvent at -80°C for 6 months or -20°C for 1 month, protected from light
- Soluble in DMSO (≥ 50 mg/mL)
- Structure consistent with 1H NMR and LCMS
Medchemexpress LLC Ilexhainanoside D | 1137648-52-2 | 664.82 | C36H56O11 | 10 MG
Ilexhainanoside D is a triterpenoid saponin extracted from Ilex hainanensis Merr. It is used in research for its reported anti-inflammatory activity and is supplied as a purified research compound (CAS 1137648-52-2). Handle and store under recommended conditions to preserve stability.
- Triterpenoid saponin isolated from Ilex hainanensis
- Reported anti-inflammatory activity in combination with ilexsaponin A1
- Molecular formula C36H56O11; molecular weight 664.82
- Store at 4°C; in solvent: -80°C for up to 6 months, -20°C for up to 1 month; protect from light
- Supplied in small research-scale quantities for laboratory use