Sugar acids and derivatives
Medchemexpress LLC Insulin Receptor Beta Antibody (YA341) | Protein A affinity purified | Predicted band size: 156 kDa; Observed band size: 95 kDa | 10 UL
Insulin Receptor Beta Antibody (YA341) is a rabbit-derived, non-conjugated IgG monoclonal antibody that targets Insulin Receptor Beta. This antibody is developed for research use only and mediates the pleiotropic actions of insulin, playing a key role in cell growth, survival, and differentiation.
- Host: rabbit
- Clonality: recombinant, monoclonal
- Species reactivity: human, rat
- Immunogen: synthetic peptide corresponding to human insulin receptor (AA range: 930-970)
- Applications: WB (1:500-1:2000), ICC/IF (1:100-1:500)
- Purity: protein A affinity purified
- Conjugation: non-conjugated
- Formulation: supplied in 1*TBS (pH7.4), 0.05% BSA, 40% glycerol, and 0.05% sodium azide
- Storage: stored at -20°C for 1 year; avoid repeated freeze/thaw cycles
- Shipping: shipped with blue ice
Medchemexpress LLC (Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) | 129622-68-0 | 99.32% | 3478.06 | 10 MG
Asn10,Leu11,D-Trp12-pTH-Related Protein (7-34) amide (human, mouse, rat) is a potent PTH-1R antagonist that does not display any partial agonist activity. This product completely blocks the antioxidant effect of PTHrP(1-37) in mouse osteoblast MC3T3-E1 and primary human osteoblasts, confirming PTH1R activation as the main signaling mechanism for the antioxidant effect of PTHrP(1-37).
- Potent PTH-1R antagonist
- Does not display partial agonist activity
- Blocks antioxidant effect of PTHrP(1-37) in osteoblast cells
- For research use only
Medchemexpress LLC Glucuronic acid sodium | 7182-77-6 | 25 MG
Glucuronic acid sodium is a polysaccharide that exhibits anti-inflammatory activity, supporting the healing of ulcerative colitis. It enhances the intestinal barrier by upregulating tight junction proteins like ZO-1 and Occludin. Additionally, Glucuronic acid sodium modulates gut microbiota by increasing beneficial bacterial populations while suppressing harmful ones.
- Exhibits anti-inflammatory activity
- Supports healing of ulcerative colitis
- Enhances intestinal barrier by upregulating tight junction proteins
- Modulates gut microbiota by increasing beneficial bacterial populations
- Suppresses harmful bacterial populations
BIOHIPPO T-bet-TAL-Puro LV
T-bet-TAL-Puro is a transcription factor reporter lentiviral vector designed to monitor the target signaling pathway in living cells The construct carries a fluorescent reporter gene under the control of pathway responsive elements and includes a puromycin selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures
AdipoGen C9-L-HSL
Chemical. CAS 177158-21-3. Formula C13H23NO3. MW 241.33. N-Nonanoyl-L-homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, controlling gene expression and affecting cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.
Medchemexpress LLC Integrin alpha 6 bet 10ug
Integrin alpha 6 beta 1 Protein Human (HEK293 Flag-His) is the recombinant human-derived Integrin alpha 6 beta 1 protein expressed by HEK293 with C-His C-Flag labeled tag has molecular weight of 110 130 kDa respectively
Medchemexpress LLC BET-IN-14 | 2243669-93-2 | C30H37N7O2 | 1 MG
BET-IN-14 is an orally active pan BET inhibitor (IC50: 5.35 nM) exhibiting anti-cancer activity. It shows anti-tumor effects against various cancer cell lines, including MM.1S, Ty-82, MV-4-11, and KG-1 cells, with an average IC50 of 174.7 nM after 72 hours. In vivo, BET-IN-14 inhibits tumor growth in MV-4-11 xenograft models.
- Orally active pan BET inhibitor
- Exhibits anti-cancer activity
- Effective against various cancer cell lines (MM.1S, Ty-82, MV-4-11, KG-1)
- Inhibits tumor growth in xenograft models
Medchemexpress LLC (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanamide | 1147883-03-1 | 99.3% | 265.30 g/mol | C14H19NO4 | 10MG
EPI-589 is a redox-active neuroprotectant under investigation for neurodegenerative disease research; it acts as an oxidoreductase inhibitor and free-radical scavenger with demonstrated blood-brain barrier permeability and oral activity in preclinical studies. The compound is supplied as a light-yellow solid with high reported purity and common small-package options suitable for in vitro and in vivo research.
- Redox-active neuroprotectant for research use.
- Reversible redox cofactor and free-radical scavenger.
- High purity (99.3%).
- Soluble in DMSO at 100 mg/mL (use freshly opened DMSO; ultrasonic assistance may be needed).
- Available in small package sizes suitable for early-stage studies.
- Solid, light yellow appearance facilitating handling and storage.
- Recommended storage: powder at -20 °C (up to 3 years) or 4 °C (up to 2 years); in solution at -80 °C (up to 6 months) or -20 °C (up to 1 month).
Chem-Impex International, Inc. 5-Bromo-4-chloro-3-indolyl-b-D-glucuronide sodium salt | 129541-41-9 | MFCD00135782 | 250MG
5-Bromo-4-chloro-3-indolyl-b-D-glucuronide sodium salt, 129541-41-9, MFCD00135782, 250MG
Medchemexpress LLC D-Iditol | 25878-23-3 | MFCD09951922 | 98.0% | 182.17 g/mol | C6H14O6 | 10 MG
D-Iditol is a fungal metabolite and sugar alcohol that accumulates in galactokinase deficiency. It is supplied as a white to off-white solid with ≥98.0% purity for research use only and is commonly used as an endogenous metabolite reference or reagent in biochemical and metabolic studies.
- High purity: 98.0% (manufacturer specification).
- Molecular weight 182.17 g/mol; formula C6H14O6.
- White to off-white solid suitable for analytical and synthetic applications.
- Stable when stored sealed at 4°C; in solvent: -80°C (6 months) or -20°C (1 month).
- Suitable for biochemical, metabolic, and analytical research workflows.
AdipoGen 3-OH-C5-DL-HSL
Chemical. CAS 148433-24-3. Formula C9H15NO4. MW 201.22. 3-Hydroxy-pentanoyl-DL-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones AHL are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.
Medchemexpress LLC Integrin alpha 5 bet 50ug | 50ug
ITGA5 is a multifunctional receptor that interacts with multiple ligands such as fibronectin fibrinogen PLA2G2A fibrillin-1 (FBN1) IL1B human metapneumovirus and soluble CD40LG ITGA5 recognizes RGD sequences and mediates cell adhesion through different binding sites Integrin alpha 5 beta 1 Protein Human (HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived Integrin alpha 5 beta 1 protein expressed by HEK293 with C-Avi C-His labeled tag Integrin alpha 5 beta 1 Protein Human (HEK293 His-Avi) has molecular weight of 100-140 kDa
Medchemexpress LLC OBI-992 drug-linker | 3039487-10-7 | 96.6% | 2173.46 | C106H162FN9O37 | 10 MG
OBI-992 drug-linker is an exatecan-based drug-linker conjugate designed for antibody-drug conjugate (ADC) synthesis. It links the TOP1 inhibitor exatecan to a cleavable linker to enable targeted delivery of the payload; preclinical studies report antitumor activity in mouse and PDX models. Supplied as a solid for research use, the product includes specified purity and storage recommendations for laboratory handling.
- Composed of exatecan linked to a cleavable linker.
- Demonstrated antitumor activity in preclinical models.
- High molecular weight compound suitable for ADC synthesis.
- Provided as a white to yellow solid.
- Purity 96.6%.
- Molecular weight 2173.46.
- Storage: sealed, away from moisture and light; in solvent -80°C for 6 months, -20°C for 1 month.
- Supplied in a 10 mg package for research use.
Medchemexpress LLC 4-Methylumbelliferyl-β-D-glucuronide hydrate | 881005-91-0 | 99.9% | 50 MG
4-Methylumbelliferyl-β-D-glucuronide hydrate is a fluorogenic substrate with excitation at 362 nm and emission at 445 nm. It is primarily used for detecting the activity of β-glucuronidase and quantifying *Escherichia coli*.
- Fluorogenic substrate for β-glucuronidase activity detection.
- Detects *Escherichia coli* count.
- Releases 4-methylumbelliferone for enzymatic reactions.
- Soluble in DMSO and H2O.
- Store at 4°C, protected from light.
Medchemexpress LLC Garcinone D | 107390-08-9 | 25 MG
Garcinone D is an activator of the STAT3/Cyclin D1 and Nrf2/HO-1 pathways and an inhibitor of CDK2/CyclinE1. It promotes neural stem cell proliferation by activating STAT3 phosphorylation and Cyclin D1 expression, and by enhancing the Nrf2/HO-1 signaling pathway. Additionally, it blocks the tumor cell cycle by inhibiting CDK2/CyclinE1.
- Activates STAT3/Cyclin D1 and Nrf2/HO-1 pathways
- Inhibits CDK2/CyclinE1 (IC50 is 28.23 μM)
- Promotes neural stem cell proliferation
- Blocks tumor cell cycle
- Can inhibit prostate and breast cancer