Sugar acids and derivatives
Medchemexpress LLC Antitumor agent-127 | 99.1% | 1670.92 | C86H107N15O18S | 10 MG
Antitumor agent-127 is a macrocyclic peptide ROR1 ligand supplied for research use. It shows nanomolar cellular binding and internalization in tumor cell lines, and is provided with supporting analytical documentation for characterization.
Apexbio Technology LLC Amyloid Beta-Peptide (1-40) (human) 131438-79-4 25mg
Amyloid Beta-Peptide (1-40) (human) (CAS 131438-79-4) is a synthetic peptide composed of 40 amino acids identical to residues 1-40 of human amyloid-beta (A ) characterized by molecular weight of 4329 8 Da Derived from amyloid precursor protein (APP) via sequential proteolytic cleavage by - and -secretases A peptides form extracellular plaques and vascular deposits commonly observed in Alzheimer s disease pathology A 40 is among the predominant isoforms generated primarily through cleavage in the transmembrane region of APP within the Golgi apparatus As a model peptide A (1-40) is widely employed to study amyloid fibril formation neurotoxicity mechanisms and therapeutic strategies targeting Alzheimer s disease progression
eMolecules 5-Methoxy-1-methyl-1H-indole-3-carbaldehyde | 39974-94-2 | MFCD01578324 | 5g
WuXi ChemSupply | 5-Methoxy-1-methyl-1H-indole-3-carbaldehyde | 5g | 599164252 | LN00140967 | 95.000 | 39974-94-2 | MFCD01578324 | 189.214 | C11H11NO2
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Medchemexpress LLC Bet bromodomain inhibitor 4 | 2407658-41-5 | ≥98.0% | 518.59 g/mol | C27H31FN8O2 | 10 MG
BET bromodomain inhibitor 4 is a small-molecule inhibitor of BET family bromodomain epigenetic reader domains supplied for research use as a 10 mg powder. It is used in preclinical studies to probe BET-mediated epigenetic regulation and assay bromodomain interactions.
- Inhibits BET bromodomain activity.
- Intended for research use only.
- Supplied as a 10 mg powder for laboratory applications.
- Target: epigenetic reader domain (BET bromodomain).
- CAS number: 2407658-41-5.
- Molecular formula: C27H31FN8O2; molecular weight: 518.59 g/mol.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years).
Medchemexpress LLC Tetrahydrouridine dihydrate | 18771-50-1 | MFCD00063468 | 99.8% | 284.26 g/mol | C9H20N2O8 | 10 MG
Tetrahydrouridine dihydrate is the dihydrated form of tetrahydrouridine, a potent competitive inhibitor of cytidine deaminase (CDA). Supplied as a white to off-white solid for research use, it is used to inhibit cytidine deamination, support studies of DNA/RNA synthesis pathways, and sensitize carcinoma cells to cytidine analog chemotherapeutics such as gemcitabine.
- Potent competitive inhibitor of cytidine deaminase (CDA).
- High purity (≈99.8%) suitable for research applications.
- Dihydrate form; molecular weight 284.26 g/mol.
- White to off-white solid, convenient for analytical and biological assays.
- Stable when stored as powder at -20°C (long-term storage).
- Available in small assay sizes for laboratory use.
Sigma Aldrich Fine Chemicals Biosciences 3dGROTM Colon Intestinal O
Patient derived organoids (PDOs) are novel in vitro 3D cell models that preserve original tissue physiology and molecular pathology thus representing a clinically-relevant alternative to traditional 2D cell lines and an effective tool to refine and reduce animal models. PDOs can be derived from adult patient biopsies or resected tissues containing native LGR5 stem cell populations and cultured within an ECM-rich substrate using specialized organoid media such as L-WRN conditioned media. Adult tissue derived organoids are phenotypically and genetically stable in long term culture presenting more mature phenotypes compared to iPSC-derived organoids. Importantly PDOs have shown to be able to predict patient clinical responses to chemotherapeutics.We are now offering a comprehensive biobank of highly characterized tissue-derived human gastrointestinal organoids from normal and diseased patients. The intestinal organoid biobank contains over 50 highly characterized intestinal organoids f
AdipoGen 3-oxo-C11-L-HSL
Chemical. CAS 216596-70-2. Formula C15H25NO4. MW 283.4. Synthetic. N-3-Oxoundecanoyl-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones AHL are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms. Numerous species of bacteria employ 3OC11-HSL in cell-to-cell communication. Shown to have immune suppressive activity, inhibiting murine and human leucocyte proliferation.
AdipoGen 3-OH-C5-DL-HSL
Chemical. CAS 148433-24-3. Formula C9H15NO4. MW 201.22. 3-Hydroxy-pentanoyl-DL-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones AHL are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.