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Filtered Search Results
AdipoGen 4-Methylumbelliferyl acetate
Chemical. CAS 2747-05-9. Formula C12H10O4. MW 218.21. Synthetic. Fluorogenic substrate for esterases, broadly applied to various types of esterases, including carboxyesterases. Measurement of intracellular pH in rat proximal convoluted tubule.
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Medchemexpress LLC Larazotide (acetate) | 881851-50-9 | MFCD31630844 | 99.2% | 785.89 g/mol | C34H59N9O12 | 1 ML
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Larazotide (acetate) is a synthetic peptide used in research to modulate tight junctions and reduce intestinal permeability. It is applied in studies of celiac disease, intestinal barrier function, and related infection models. The product is supplied with molecular data and solubility guidance to support experimental preparation and formulation of stock solutions.
- Synthetic peptide zonulin antagonist.
- Intended for research use only.
- Includes molecular weight and formula data.
- Provides solubility and stock solution preparation guidance.
- Available in multiple small-scale packaging sizes for laboratory use.
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Medchemexpress LLC CBP-501 (acetate) | 1929.06 (free base) | 1 MG
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CBP-501 acetate is a cell-permeable calmodulin-binding peptide and a G2-abrogating drug candidate. It inhibits the activity of multiple Ser216-specific kinases, including MAPKAP-K2, C-Tak1, CHK1, and CHK2. It is used for various types of cancer and enhances the cytotoxicity of CDDP and Bleomycin against cancer cells both in vitro and in vivo.
- Inhibits MAPKAP-K2 with an IC50 of 0.9 μM
- Inhibits C-Tak1 with an IC50 of 1.4 μM
- Inhibits Chk1 with an IC50 of 3.4 μM
- Inhibits Chk2 with an IC50 of 6.5 μM
- Stable for 2 years at -80°C as powder
- Stable for 1 year at -20°C as powder
- Stable for 6 months at -80°C in solvent
- Stable for 1 month at -20°C in solvent
- Enhances cytotoxicity of CDDP and Bleomycin
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Medchemexpress LLC Farnesyl pyrophosphate ammonium | 116057-57-9 | 95.39% | 433.42 | 1 MG
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Farnesyl pyrophosphate ammonium is a metabolic intermediate in the mevalonate (MVA) pathway. It acts as a TRP channel (TRPM2) agonist, triggering Ca2+ influx and cell death. It is a crucial branch substrate for various biological syntheses and is utilized in research concerning a range of diseases.
- Acts as a TRP channel (TRPM2) agonist
- Triggers Ca2+ influx and cell death
- Key branch substrate for cholesterol synthesis
- Key branch substrate for ubiquinone synthesis
- Key branch substrate for protein farnesylation
- Key branch substrate for geranylgeranyl pyrophosphate (GGPP) synthesis
- Used in research on cerebral ischemia
- Used in research on neurodegenerative diseases
- Used in research on pancreatic cancer
- Used in research on inflammation
- Used in research on autoimmune diseases
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Medchemexpress LLC PNC-27 acetate | 99.98% | 4031.73 (free base) | 10 MG
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PNC-27 acetate is a chimeric p53-penetratin peptide that binds to HDM-2 in a p53 peptide-like structure, inducing selective membrane-pore formation and leading to cancer cell lysis. It is an anticancer peptide that can be used in acute myeloid leukemia research.
- Binds to HDM-2 in a p53 peptide-like structure.
- Induces selective membrane-pore formation.
- Leads to cancer cell lysis.
- Anticancer peptide.
- Can be used in acute myeloid leukemia research.
- Induces cancer cell death (e.g., 100% cell death in MIA-PaCa-2 cells in 90 minutes at 50 μg/mL).
- Shows anti-leukemia activity in mice (e.g., reduced AML engraftment and prolonged survival at 40 mg/kg intraperitoneal injection once daily for 2-3 weeks).
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Medchemexpress LLC PNC-27 acetate | 99.98% | 4031.73 (free base) | 100 MG
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PNC-27 acetate is a chimeric p53-penetratin peptide that binds to HDM-2 in a p53 peptide-like structure.
- Induces selective membrane-pore formation, leading to cancer cell lysis.
- Utilized in acute myeloid leukemia research.
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Medchemexpress LLC SOR-C13 acetate | 10MG
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SOR-C13 acetate | 10MG
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TARGETMOL CHEMICALS INC ATOSIBAN ACETATE 10MG
Also available in 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Atosiban acetate (RW22164) is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban acetate (RW22164) inhibits the oxytocin-mediated release of inositol trisphosphate from the myometrial cell membrane. There is reduced release of intracellular stored calcium from the sarcoplasmic reticulum of myometrial cells and reduced influx of Ca2+ from the extracellular space through voltage gated channels. Atosiban acetate (RW22164) suppresses oxytocin-mediated release of PGE and PGF from the decidua. In human pre-term labor atosiban at the recommended dosage antagonizes uterine contractions and induces uterine quiescence. The onset of uterus relaxation following atosiban is rapid reduced within 10 minutes. purity: 99%
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Cayman Chemical DLTryptophn octyl esTRhy 500mg
A stable, cell-permeable tryptophan derivative with an octyl ester protected COOH group
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Medchemexpress LLC L-NMMA acetate | 53308-83-1 | 99.0% | 248.28 | 100 MG
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L-NMMA acetate is a nitric oxide synthase inhibitor of all NOS isoforms including NOS1, NOS2, and NOS3. The Ki values for nNOS (rat), eNOS (human), and iNOS (mouse) are approximately 0.18, 0.4, and 6 μM, respectively.
- Functions as a nitric oxide synthase inhibitor.
- Inhibits all NOS isoforms (NOS1, NOS2, and NOS3).
- Demonstrates Ki values for nNOS (rat) of approximately 0.18 μM.
- Demonstrates Ki values for eNOS (human) of approximately 0.4 μM.
- Demonstrates Ki values for iNOS (mouse) of approximately 6 μM.
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Medchemexpress LLC R5 peptide acetate | 1MG
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R5 peptide acetate | 1MG
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Medchemexpress LLC Bio-11006 acetate | 00-00-0 | 99.9% | 1110.22 g/mol | C48H79N13O17 | 50 MG
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BIO-11006 acetate is the acetate salt form of a peptide analog of the MANS peptide that inhibits MARCKS (myristoylated alanine-rich C kinase substrate). It is supplied for research use and is available as lyophilized peptide vials or as a ready-to-use aqueous solution.
- Inhibits MARCKS protein by mimicking the MANS peptide.
- Peptide acetate salt format for improved handling and solubility.
- Chemical formula C48H79N13O17.
- Molecular weight 1110.22 g/mol.
- Purity 99.92%.
- Available in multiple pack sizes, including 50 mg and 10 mM 1 mL solution.
- For research use only.
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AdipoGen Isoeugenyl acetate
Chemical. CAS 93-29-8. Formula C12H14O3. MW 206.2. Isoeugenol is used as a fragrance material in perfumes and perfumed products. It is a moderate to strong skin allergen and a frequent cause of contact allergy. Isoeugenyl acetate has been used as a substitute for Isoeugenol, but is probably easily hydrolysed in the skin to produce isoeugenol. Isoeugenyl acetate is a useful building block and has antibacterial and antifungal properties. Compound can be used as analytical reference material.
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Medchemexpress LLC CBP-501 acetate | 1829512-40-4 | 99.8% | 1,989.1 g/mol | C88H126F5N29O19 | 10 MG
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CBP-501 acetate is a cell-permeable calmodulin-binding peptide supplied as a powder for research use. It acts as a G2 checkpoint abrogator, sensitizes cells to DNA-damaging agents, and inhibits multiple Ser216-specific kinases.
- Cell-permeable calmodulin-binding peptide.
- G2 checkpoint abrogator that sensitizes cells to DNA damage.
- Inhibits multiple Ser216-specific kinases such as CHK1 and CHK2.
- Peptide sequence: d({4-Bz-Phe}-Ser-Trp-Ser-{pentafluoro-Phe}-{Cha}-Arg-Arg-Arg-Gln-Arg-Arg).
- Physical form: powder; sealed storage away from moisture, store at -80°C or -20°C per handling instructions.
- High purity (~99.8%) suitable for research applications.
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Medchemexpress LLC Delmitide acetate | 501019-16-5 | 99.2% | 1288.62 g/mol | C61H109N17O13 | 50 MG
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Delmitide acetate is an orally active D-isomer decapeptide with potent anti-inflammatory activity. It inhibits production of TNF-α, IFN-γ, and interleukin-12, and up-regulates heme oxygenase-1 activity. It is provided for research use in studies of inflammatory diseases such as ulcerative colitis.
- Orally active d-isomer decapeptide.
- Potent inhibition of proinflammatory cytokines (TNF-α, IFN-γ, IL-12).
- Up-regulates heme oxygenase-1 activity.
- Suitable for inflammatory disease research applications.
- Supplied as an acetate salt with reported high purity.
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