Drug Standards
Medchemexpress LLC Manidipine | 89226-50-6 | 99.9% | 10 MM 1 ML
Manidipine is an orally active calcium channel antagonist. It regulates the expression of cytokines (IL-1β, IL-6) and has a hypotensive effect. It can be used in the study of cardiovascular diseases (such as hypertension, myocardial ischemia-reperfusion injury, ventricular hypertrophy), kidney diseases (such as glomerular diseases), and epilepsy.
- Orally active calcium channel antagonist
- Regulates expression of cytokines (IL-1β, IL-6)
- Has a hypotensive effect
- Used in studies of cardiovascular diseases, kidney diseases, and epilepsy
- Inhibits transcription of mRNA for IL-1β and GM-CSF
- Reduces systolic blood pressure in animal models
Medchemexpress LLC Proguanil (hydrochloride) | 637-32-1 | 99.2% | 100 MG
Proguanil hydrochloride is an antimalarial proagent that is metabolized into its active metabolite, Cycloguanil. It acts as a dihydrofolate reductase (DHFR) inhibitor, primarily used in research to study malaria and its related pathways.
- Functions as a dihydrofolate reductase (DHFR) inhibitor
- Metabolized into active form Cycloguanil for antimalarial activity
- Synergistic effects when combined with Atovaquone
- Active against gametocytes and pre-erythrocytic stages of malaria parasites
- Reversibly inhibits 5-HT3 receptor responses
- Intended for research use only
Medchemexpress LLC Hydroxy itraconazole | 112559-91-8 | 99.8% | 10 MG
Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), a triazole antifungal agent. It has reported antifungal activity in vitro and inhibits CYP3A. This product is for research use only.
- Active metabolite of itraconazole
- Triazole antifungal agent
- Exhibits antifungal activity in vitro
- Inhibits CYP3A
- Molecular weight: 721.63
- Chemical formula: C35H38Cl2N8O5
- Appearance: White to off-white solid
- Soluble in DMSO (83.33 mg/mL)
- Insoluble in H2O (< 0.1 mg/mL)
- Store solid at 4°C, protected from light
- Store in solvent at -80°C for 6 months, or -20°C for 1 month (protected from light)
Medchemexpress LLC Doxycycline hyclate (Standard) | 24390-14-5 | 512.94 | 50 MG
Doxycycline hyclate (Standard) is the analytical standard of Doxycycline hyclate. It is an antibiotic, an orally active and broad-spectrum metalloproteinase (MMP) inhibitor, showing antibacterial activity and anti-cancer cell proliferation activity. It is intended for research and analytical applications.
- Used as an analytical standard.
- Reference standard supplied assay.
- Used in qualitative, quantitative, and methodological research experiments.
- Applicable in HPLC, GC, and MS.
- Shows antibacterial activity.
- Shows anti-cancer cell proliferation activity.
- Orally active and broad-spectrum metalloproteinase (MMP) inhibitor.
Sigma Aldrich Fine Chemicals Biosciences Fenbendazole Related Compound B United States Pharmacopeia (USP) Reference Standard | 20367-38-8 | 30MG
Fenbendazole Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 225.63 | 20367-38-8 | 30MG
Apexbio Technology LLC Gonadorelin Acetate 71447-49-9 10mg
Gonadorelin Acetate is a synthetic peptide agonist targeting gonadotropin-releasing hormone (GnRH) receptors It is designed to bind specifically to GnRH receptors on pituitary gonadotrophs thereby modulating secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) Gonadorelin Acetate exerts its biological activity primarily through receptor-mediated regulation of the reproductive hormone axis Based on these pharmacological properties Gonadorelin Acetate holds research potential in studies of reproductive hormone signaling pathways endocrine regulation associated with infertility disorders and characterization of gonadotropin responses in cellular or animal models
Apexbio Technology LLC Salmeterol xinafoate 94749-08-3 10mM (in 1mL DMSO)
Salmeterol xinafoate (CAS 94749-08-3) is a long-acting 2-adrenergic receptor agonist that induces smooth muscle relaxation leading to bronchodilation and vasodilation In vitro studies show that salmeterol reduces retinal M ller cell death by inhibiting IRS-1 (Ser307) phosphorylation implicating -adrenergic signaling in cell survival pathways In vivo experiments demonstrate that salmeterol suppresses pro-inflammatory cytokine production in allergen-stimulated murine models and attenuates inflammatory responses via modulation of dendritic cells Clinically salmeterol has been shown to enhance peak expiratory flow in asthma and is studied in combination therapies for persistent asthma supporting its utility in respiratory and immunological research
Medchemexpress LLC Amoxicillin | 26787-78-0 | 99.9% | 10 G
Amoxicillin is an antibiotic known for its good oral absorption and broad-spectrum antimicrobial activity. It functions by inhibiting the biosynthesis of polypeptides in the bacterial cell wall, which in turn hinders cell growth.
- Possesses good oral absorption
- Provides broad-spectrum antimicrobial activity
- Inhibits bacterial cell wall biosynthesis
- Used in various cellular and in vivo research models
Medchemexpress LLC Carteolol hydrochloride | 51781-21-6 | 99.6% | 328.8343 | 5 MG
Carteolol hydrochloride (OPC-1085 hydrochloride) is a non-selective beta blocker used to treat glaucoma, as well as an anti-arrhythmia, anti-angina, and antihypertensive agent. It has a protective action against UVB-induced HCEC damage, with its radical scavenging ability potentially being an important basis for this effect. A new alginate formulation of long-acting carteolol 1% given once daily is as effective as standard 1% carteolol given twice daily, with no significant differences in safety.
- Used to treat glaucoma
- Functions as an anti-arrhythmia agent
- Acts as an anti-angina agent
- Serves as an antihypertensive agent
- Protective action against UVB-induced HCEC damage
- Radical scavenging ability
Medchemexpress LLC Plerixafor octahydrochloride | 155148-31-5 | MFCD04974488 | 99.1% | 794.47 g/mol | C28H62Cl8N8 | 10 MG
Plerixafor octahydrochloride is a small-molecule selective antagonist of the CXCR4 chemokine receptor provided for laboratory research use. It exhibits reported CXCR4 inhibitory activity and is used in studies of stem cell mobilization, HIV, cancer, and immunology.
- Selective CXCR4 antagonist with IC50 44 nM.
- Chemical formula C28H62Cl8N8 and molecular weight 794.47 g/mol.
- High purity (≈99.1%) suitable for analytical and research applications.
- CAS number 155148-31-5 for unambiguous substance identification.
- Supplied in milligram-scale packages for laboratory research.
Medchemexpress LLC Butylparaben (standard) | 94-26-8 | 98.9% | 100 MG
Butylparaben (Standard) is the analytical standard of Butylparaben. It is an organic compound used as an antimicrobial preservative in cosmetics, in active molecule suspensions, and as a food flavoring additive. This product is intended for research and analytical applications, particularly as a reference standard in qualitative, quantitative, and methodological research experiments using techniques like HPLC, GC, and MS.
- Analytical standard
- Used as an antimicrobial preservative in cosmetics
- Found in active molecule suspensions
- Used as a food flavoring additive
- Intended for research and analytical applications
- Reference standard for qualitative, quantitative, and methodological research
- Suitable for techniques such as HPLC, GC, and MS
Medchemexpress LLC Stearyl arachidate 50mg
Stearyl arachidate is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Sigma Aldrich Fine Chemicals Biosciences Glyburide Related Compound B United States Pharmacopeia (USP) Reference Standard | 21165-77-5 | 25MG
Glyburide Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 426.87 | 21165-77-5 | 25MG
Sigma Aldrich Fine Chemicals Biosciences Spironolactone Related Compound C United States Pharmacopeia (USP) Reference Standard | 976-70-5 | 30MG
Spironolactone Related Compound C United States Pharmacopeia (USP) Reference Standard | Mol Wt: 342.47 | 976-70-5 | 30MG
TARGETMOL CHEMICALS INC Tiamulin fumarate 1G
Also available in 1 mL, 25 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Tiamulin fumarate （Thiamutilin fumarate） is a semisynthetic diterpenoid antibiotic with antibacterial activity and inhibition of protein synthesis, which can be used to study pneumocystis. Purity 99.64%