Drug Standards
Apexbio Technology LLC Eltrombopag Olamine 496775-62-3 25mg
Eltrombopag Olamine is an orally bioavailable thrombopoietin receptor (c-mpl) agonist that directly stimulates platelet production through activation of the JAK2/STAT signaling pathway In cellular assays using murine BAF3 cells expressing human thrombopoietin receptor (hTpoR) eltrombopag induced STAT-dependent signaling responses with an EC50 value of approximately 0 27 M This compound promotes differentiation of human CD34 progenitor cells into megakaryocytes capable of platelet production Eltrombopag is commonly applied in hematological research particularly in studies involving thrombocytopenia and thrombopoiesis-related mechanisms
Apexbio Technology LLC Boceprevir 394730-60-0 10mM (in 1mL DMSO)
Boceprevir is an oral inhibitor targeting hepatitis C virus (HCV) NS3 protease an enzyme essential for processing viral polyproteins during HCV replication The compound binds directly and reversibly to the NS3 enzyme s active site forming a covalent adduct through its ketoamide functionality Cell-based replicon assays demonstrated that boceprevir inhibits HCV replication in cultured hepatocytes with an IC90 of approximately 350 nM In preclinical studies boceprevir exhibited favorable selectivity towards HCV NS3 relative to human neutrophil elastase Commonly boceprevir is used in research investigating HCV replication mechanisms and NS3 enzyme function as well as in antiviral combination assays involving interferon-based regimens
Medchemexpress LLC Carbidopa | 28860-95-9 | 99.8% | 10 MM 1 ML
Carbidopa, also known as (S)-(-)-Carbidopa, is a peripheral decarboxylase inhibitor primarily used for research related to Parkinson's disease. It also functions as a selective aryl hydrocarbon receptor (AhR) modulator and has been shown to inhibit pancreatic cancer cell and tumor growth.
- Acts as a peripheral decarboxylase inhibitor
- Functions as a selective aryl hydrocarbon receptor (AhR) modulator
- Demonstrates anticancer activity by inhibiting pancreatic cancer cell and tumor growth
- High purity of 99.84% ensures reliability for research applications
- Comprehensive documentation available, including Data Sheet, COA, SDS, HNMR, RP-HPLC, and Handling Instructions
- Detailed solubility information provided for in vitro and in vivo applications, with protocols for preparing clear stock and working solutions
- Intended for research use only
U.S. Pharmacopeia Epinephrine bitartrate, 51-42-3, MFCD00035077, 200 mg
Empirical Formula (Hill Notation): C9H13NO3 · C4H6O6, Molecular Weight: 333.29, Synonym: (−)-Epinephrine (+)-bitartrate salt, L-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol D-hydrogen bitartrate salt, L-Adrenaline (+)-bitartrate salt, L-Adrenaline D-hydrogentartrate, L-Epinephrine D-hydrogentartrate.
Selleck Chemical LLC Lapatinib (GW-572016) Ditosylate 10mM/1mL 388082-77-7
Lapatinib (GW-572016) Ditosylate is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Stearyl gallate | 10361-12-3 | 10 G
Stearyl gallate is an alkyl gallate characterized by a long alkyl chain (18 carbons). It demonstrates both antioxidant activity and weak antiviral properties, specifically against HSV-1.
- Exhibits antioxidant activity
- Shows weak antiviral activity against HSV-1
- Has a purity of 99.50%
- Appears as a white to off-white solid
- Stable under recommended storage conditions
- Melting point of 95°C
- Soluble in DMSO
Medchemexpress LLC Stearyl gallate | 10361-12-3 | 100 G
Stearyl gallate is an alkyl gallate characterized by a long alkyl chain consisting of 18 carbon atoms. It exhibits antioxidant activity and a weak antiviral activity against HSV-1. For research use only.
- Alkyl gallate with an 18-carbon alkyl chain.
- Has antioxidant activity.
- Possesses weak antiviral activity against HSV-1.
- Purity: 99.50%.
- Appearance: Solid, white to off-white.
- Molecular weight: 422.60.
- Formula: C25H42O5.
- Soluble in DMSO (116.67 mg/mL or 276.08 mM).
- Potential applications in research related to antiviral and antioxidant studies.
- Available as a solid or in pre-made DMSO solutions for convenience.
- Detailed documentation including Data Sheet, COA, SDS, HNMR, LCMS, and Handling Instructions are provided.
- Can be used in various concentrations by preparing stock solutions.
Medchemexpress LLC Ruxolitinib (Standard) | 941678-49-5 | 99.7% | C₁₇H₁₈N₆ | 50 MG
Ruxolitinib (Standard) is the analytical standard of Ruxolitinib, intended for research and analytical applications. It is a potent and selective JAK1/2 inhibitor, inducing autophagy and killing tumor cells through toxic mitophagy. This compound is commonly used in qualitative, quantitative, and methodological research experiments.
- Used as an analytical standard in reference assays
- Suitable for HPLC, GC, and MS research experiments
- Store at 4°C, sealed, away from light and moisture
Medchemexpress LLC Glipizide (Standard) | 29094-61-9 | MFCD00870381 | 99.7% | 50 MG
Glipizide (Standard) is the analytical standard of Glipizide. It is intended for research and analytical applications. Glipizide (CP 2872; K 4024) is a potent, orally active sulfonylurea class anti-diabetic agent used for type 2 diabetes mellitus research, but not for type 1. It functions by partially blocking ATP-sensitive potassium (KATP) channels in the β cells of pancreatic islets of Langerhans.
- Supplied as an assay reference standard.
- Commonly used in qualitative, quantitative, and methodological research experiments, including HPLC, GC, and MS.
- Potent, orally active sulfonylurea class anti-diabetic agent.
- Partially blocks ATP-sensitive potassium (KATP) channels in pancreatic β cells.
Apexbio Technology LLC Tenofovir 147127-20-6 10mM (in 1mL DMSO)
Tenofovir is an antiviral compound acting as an inhibitor of HIV reverse transcriptase specifically targeting RNA-dependent DNA polymerase to impede the replication cycle of HIV It interferes with the transcription process by competitively binding to the enzyme thereby preventing viral RNA from being transcribed into complementary DNA In vitro investigations indicate that Tenofovir inhibits viral replication as evidenced by an IC50 value of approximately 1 5 M in SIV-infected C-8166 cell assays Due to this inhibitory mechanism and antiviral activity against HIV Tenofovir is widely employed in biomedical and pharmacological research focused on HIV infection antiviral drug development and related studies involving reverse transcriptase enzymatic activity
Medchemexpress LLC Crizotinib | 877399-52-5 | 99.97% | C21H22Cl2FN5O | 1 ML
Crizotinib is an orally bioavailable, ATP-competitive inhibitor of ALK, c-Met, and ROS1. It inhibits tyrosine phosphorylation in cell-based assays and demonstrates effective tumor growth inhibition. This product is for research use only.
- Orally bioavailable ALK, c-Met, and ROS1 inhibitor
- Inhibits tyrosine phosphorylation of NPM-ALK and c-Met
- Demonstrates effective tumor growth inhibition
- Powder storage: -20°C for 3 years; 4°C for 2 years
- In-solvent storage: -80°C for 1 year; -20°C for 6 months
Medchemexpress LLC Mogroside IV | 89590-95-4 | 100 MG
Mogroside IV is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, acting as a nonsugar sweetener. Mogrosides are known to be sweeter than sucrose and exhibit antioxidant, antidiabetic, and anticancer activities.
- Triterpenoid glycoside
- Nonsugar sweetener
- Sweeter than sucrose
- Exhibits antioxidant, antidiabetic, and anticancer activities
- Isolated from Luo Han Guo extracts
- Useful in food and metabolic disease research
Medchemexpress LLC Glipizide (Standard) | 29094-61-9 | 99.7% | 100 MG
Glipizide (Standard) is an analytical standard intended for research and analytical applications. This potent, orally active sulfonylurea class anti-diabetic agent is used for type 2 diabetes mellitus research, acting by partially blocking ATP-sensitive potassium channels among β cells of pancreatic islets of Langerhans.
- Analytical standard for research and analytical applications
- Potent, orally active sulfonylurea class anti-diabetic agent
- Used for type 2 diabetes mellitus research
- Acts by partially blocking ATP-sensitive potassium (KATP) channels
- Reference standard supplied assay
- Commonly used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS