Drug Standards
U.S. Pharmacopeia Hydrochlorothiazide, 58-93-5, MFCD00051765, 200 mg
Empirical Formula (Hill Notation): C7H8ClN3O4S2, Molecular Weight: 297.74, Synonym: 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-Chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide.
Selleck Chemical LLC Mirabegron 5mg 223673-61-8 YM 178
Mirabegron (YM 178) is a selective ?3-adrenoceptor agonist with EC50 of 22.4 nM. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Sigma Aldrich Fine Chemicals Biosciences Abacavir sulfate European Pharmacopoeia (EP) Reference Standard | 188062-50-2 |
Abacavir sulfate European Pharmacopoeia (EP) Reference Standard | Mol Wt: 670.74 | 188062-50-2 |
Medchemexpress LLC Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) | 61336-70-7 | ≥98% | 50 MG
Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) is an antibiotic with good oral absorption and broad-spectrum antimicrobial activity. It inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth.
- Good oral absorption.
- Broad-spectrum antimicrobial activity.
- Inhibits cell wall polypeptide biosynthesis.
- Inhibits cell growth.
- Decreases living cells and increases cell wall rupture (in vitro).
- Inhibits bacterial numbers (in vivo).
- Improves activity against *Chlamydia trachomatis* infection (in vivo).
Sigma Aldrich Fine Chemicals Biosciences Trandolapril Related Compound D United States Pharmacopeia (USP) Reference Standard | 149881-40-3 | 25MG
Trandolapril Related Compound D United States Pharmacopeia (USP) Reference Standard | Mol Wt: 412.52 | 149881-40-3 | 25MG
Selleck Chemical LLC Camptothecin 100mg 7689-03-4 NSC-100880, CPT
Camptothecin (NSC-100880, CPT) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 ?M in a cell-free assay. Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC D-mannosamine hydrochloride | 5505-63-5 | MFCD00064557 | ≥98.0% | 215.63 g·mol⁻¹ | C6H14ClNO5 | 100 G
D-Mannosamine hydrochloride is a six-carbon amino sugar used as a biochemical reagent to probe mannose-related pathways and receptors in glycobiology research. It is supplied as a white to off-white solid with high purity suitable for laboratory applications.
- High purity suitable for analytical and preparative use.
- White to off-white solid, easy to weigh and dissolve for solution preparation.
- Useful as a probe for mannose receptor and glycan pathway studies.
- Stable under refrigerated storage when kept under inert atmosphere.
- Available in multiple laboratory pack sizes for research flexibility.
Medchemexpress LLC Hydrochlorothiazide (Standard) | 58-93-5 | 99.55% | 25 MG
Hydrochlorothiazide (Standard) is an analytical standard of Hydrochlorothiazide, intended for research and analytical applications. It is an orally active diuretic agent of the thiazide class, known for inhibiting the transforming TGF-β/Smad signaling pathway and exhibiting direct vascular relaxant effects by opening the calcium-activated potassium (KCA) channel. This compound improves cardiac function, reduces fibrosis, and possesses an antihypertensive effect. With a molecular weight of 297.74 and a formula of C₇H₈ClN₃O₄S₂, it appears as a white to off-white solid.
- Used as a reference standard for assays
- Commonly used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
- Improves cardiac function
- Reduces fibrosis
- Antihypertensive effect
Medchemexpress LLC 1-((3-fluorophenyl)carbamoyl)cyclopropane-1-carboxylic acid | 1247859-37-5 | MFCD16676122 | 100mg
Cabozantinib impurity 7 is an impurity of Cabozantinib (HY-13016)
Medchemexpress LLC D-phenylalanine, 3-(methylsulfonyl)-, phenylmethyl ester, hydrochloride | 2049127-88-8 | 250mg
Lifitegrast impurity 4 hydrochloride is an impurity of Lifitegrast (HY-19344)
Sigma Aldrich Fine Chemicals Biosciences Retinyl palmitate potency5G
Retinyl palmitate or vitamin A palmitate is a retinoid which is an acid form of vitamin A. Retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinyl palmitate is a major storage form of vitamin A found in epidermis. Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed.
Selleck Chemical LLC Vandetanib S1046-25mg
Vandetanib is a potent inhibitor of VEGFR2 with IC50 of 40 nM in a cell-free assay It also inhibits VEGFR3 and EGFR with IC50 of 110 nM and 500 nM respectively Not sensitive to PDGFR Flt1 Tie-2 and FGFR1 with IC50 of 1 1-3 6 M No activity against MEK CDK2 c-Kit erbB2 FAK PDK1 Akt and IGF-1R with IC50 above 10 M Vandetanib (ZD6474) increases apoptosis and induces autophagy by increasing the level of reactive oxygen species (ROS)
Medchemexpress LLC LY-2584702 (tosylate salt) | 1082949-68-5 | 99.5% | 617.62 | 10 MG
LY-2584702 tosylate salt is a selective ATP competitive inhibitor of p70S6K with an IC50 of 4 nM. In the S6K1 enzyme assay, the IC50 of LY-2584702 is 2 nM. It inhibits phosphorylation of the S6 ribosomal protein in HCT116 colon cancer cells and demonstrates significant single-agent efficacy in glioblastoma and colon carcinoma xenograft models.
- Selective ATP competitive inhibitor of p70S6K.
- Inhibits phosphorylation of the S6 ribosomal protein in HCT116 colon cancer cells.
- Demonstrates significant single-agent efficacy in glioblastoma and colon carcinoma xenograft models.
- Inhibits S6K activity in EOMA cells.
- Inhibits proliferation of A549 and SK-MES-1 cells.
Medchemexpress LLC Lenalidomide-4-aminomethyl hydrochloride | 444289-05-8 | MFCD32703223 | 90.9% | C14H16ClN3O3 | 10MG
Lenalidomide-4-aminomethyl hydrochloride is a lenalidomide-derived cereblon (CRBN) ligand used to recruit the CRBN E3 ubiquitin ligase for targeted protein degradation. It is commonly employed as the E3-binding moiety in PROTAC construction and can be conjugated to target ligands via a synthetic linker; supplied as the hydrochloride salt to aid handling and solubility.
- Lenalidomide-based cereblon (CRBN) ligand for targeted protein degradation.
- Suitable for use as the E3-binding moiety in PROTAC design and synthesis.
- Hydrochloride salt form facilitates conjugation and handling in synthetic workflows.
- Reported purity 90.9%; verify certificate of analysis for critical applications.
- Provided for research use under appropriate laboratory safety conditions.
Selleck Chemical LLC Pimavanserin 10mg 706782-28-7 ACP-103
Pimavanserin (ACP-103) is a potent and selective serotonin 5-HT2A inverse agonist with pIC50 of 8.73, used to treat psychosis associated with Parkinson¿s disease. *For Research & Development use only. Product is not intended for drug, household, or human consumption.