Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Finasteride United States Pharmacopeia (USP) Reference Standard | 98319-26-7 | MFCD00869737 | 200MG
Finasteride United States Pharmacopeia (USP) Reference Standard | Mol Wt: 372.54 | 98319-26-7 | MFCD00869737 | 200MG
Medchemexpress LLC Mogroside I A1 | 88901-46-6 | 1 MG
Mogroside I A1 is a triterpenoid glycoside and a nonsugar sweetener. It is known for being sweeter than sucrose and exhibits antioxidant, antidiabetic, and anticancer activities.
- Triterpenoid glycoside
- Nonsugar sweetener, sweeter than sucrose
- Exhibits antioxidant, antidiabetic, and anticancer activities
- Store at 4°C, protected from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
Med Vet International Ketoconazole Tablets (Nizoral), 200mg, 100ct
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
Ketoconazole a generic version of Nizoral is used to treat fungal and yeast infections on skin, hair, nails, and blood.
Medchemexpress LLC Lidocaine impurity 1 | 39084-88-3 | 99.9% | 232.11 | 50 MG
Lidocaine impurity 1 is an impurity of Lidocaine. It is for research use only and not sold to patients. The appearance is solid, and the formula is C10H11Cl2NO.
- Appearance: Solid
- Formula: C10H11Cl2NO
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage (powder): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
- Usage: For research use only
Medchemexpress LLC Aprepitant impurity 1 | 170729-76-7 | 100 MG
Defluoro aprepitant is an analytical standard intended for research and analytical applications. This product is for research use only.
- Analytical and reference standard for assay
- Suitable for qualitative, quantitative, and methodological research
- Applicable in HPLC, GC, and MS experiments
Sigma Aldrich Fine Chemicals Biosciences Ifosfamide impurity F European Pharmacopoeia (EP) Reference Standard | 40722-73-4 |
Ifosfamide impurity F European Pharmacopoeia (EP) Reference Standard | Mol Wt: 218.02 | 40722-73-4 |
Apexbio Technology LLC Diphemanil Methylsulfate 62-97-5 10mM (in 1mL DMSO)
Diphemanil Methylsulfate (CAS 62-97-5) is a synthetic quaternary ammonium compound that acts as an anticholinergic agent by competitively inhibiting muscarinic acetylcholine receptors This blockade reduces the activity of the parasympathetic nervous system leading to decreased secretory and smooth muscle activity Diphemanil Methylsulfate is utilized in biomedical research to investigate cholinergic pathways autonomic nervous system modulation and the physiological regulation of glandular secretions or gastrointestinal motility Its defined mechanism makes it a useful tool in studies of receptor pharmacology and neurotransmitter-mediated signaling
Medchemexpress LLC Fostamatinib disodium hexahydrate | 914295-16-2 | 99.5% | 1 ML
Fostamatinib disodium hexahydrate (R788 disodium hexahydrate) is the oral prodrug of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. It also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).
- Oral prodrug of R406
- Orally available and competitive Syk/FLT3 inhibitor
- Inhibits Lyn (IC50=63 nM)
- Inhibits Lck (IC50=37 nM)
- Shows cytotoxicity in Ramos cells (IC50 = 0.267 μM)
- Highly bioavailable and rapidly absorbed
- Inhibits phosphorylated TBK1 and IRF3 in THP-1 cells
- Impacts proliferative capacity of PC-3 cells
- Improves survival in mice transplanted with TEL-SYK oncogene
- Reduces spleen and liver sizes
- Decreases white blood cell counts
Cayman Chemical OxIbendazole 50mg
A benzimidazole anthelmintic; inhibits binding of [3H]mebendazole to H. contortus L3 larval tubulin and inhibits mammalian tubulin polymerization (IC50s = 0.3 and 2.2 µM, respectively); reduces fecal worm egg counts in dogs and cats by greater than 90% for the nematodes T. canis, T. vulpis, A. caninum, and T. leonine at 15 mg/kg in combination with niclosamide; reduces fecal egg counts of strongyles in horses at 10 mg/kg per day
Medchemexpress LLC Chitosan | 9012-76-4 | MFCD00161512 | >=80% | 100 G
Chitosan is a polysaccharide obtained by deacetylating chitin, exhibiting antimicrobial activity against various bacteria and fungi. It is a polycationic linear polysaccharide derived from chitin, known for its versatility as a biomaterial due to its non-toxicity, low allergenicity, biocompatibility, and biodegradability. Chitosan also possesses antitumor, antibacterial, antifungal, and antioxidant activities.
- Polysaccharide obtained by deacetylating chitin.
- Exhibits antimicrobial activity against various bacteria and fungi.
- Polycationic linear polysaccharide.
- Versatile biomaterial.
- Non-toxicity, low allergenicity, biocompatibility, and biodegradability.
- Antitumor, antibacterial, antifungal, and antioxidant activities.
Medchemexpress LLC Fluticasone propionate | 80474-14-2 | 99.93% | 25 MG
Fluticasone propionate is a potent topical anti-inflammatory corticosteroid and a selective glucocorticoid receptor agonist with an absolute affinity (KD) of 0.5 nM. It exhibits little or no activity at other steroid receptors and also shows anti-viral activity.
- Inhibits TNFα-induced E-selectin expression with an IC50 of 1 nM.
- Shows EC50 of 0.7 nM for transactivation activity at the glucocorticoid receptor in HepG2 cells.
- Exhibits ED50 of 3 μg for antiinflammatory activity in neutrophils.
- Provides IC50 of 0.1 nM for inhibition of TNFalpha release in PBMC.
- Demonstrates EC50 of 1.09 nM for agonist activity at GR in SW1353 cells.
Medchemexpress LLC 5-Aza-7-deazaguanine | 67410-64-4 | 99.9% | 151.13 | 100 MG
5-Aza-7-deazaguanine is a substrate for wild-type (WT) E. coli purine nucleoside phosphorylase and its Ser90Ala mutant in the synthesis of base-modified nucleosides.
- Functions as a substrate for wild-type E. coli purine nucleoside phosphorylase.
- Functions as a substrate for Ser90Ala mutant in the synthesis of base-modified nucleosides.
- Targets purine nucleoside phosphorylase and nucleoside antimetabolite/analog.
Apexbio Technology LLC Loxapine 1977-10-2 500mg
Loxapine is a dibenzoxazepine derivative functioning as an antagonist at serotonin (5-HT) and dopamine receptors notably displaying high affinity towards 5-HT2 and dopamine D4 receptor subtypes It serves as an inhibitor of serotonin 5-HT2 receptors (human and bovine frontal cortex membranes Ki approximately 6 2-6 6 nM) Additionally Loxapine suppresses dopamine D2 and D4 receptor activities and modulates cytokine release reducing interleukin IL-1 and IL-2 secretion in LPS-stimulated rat glial cell cultures at concentrations ranging from 0 2 to 20 M Given these properties Loxapine is utilized as a pharmacological tool in research exploring serotonergic and dopaminergic signaling pathways relevant to psychiatric disorders and neuroinflammatory processes
Medchemexpress LLC Benazepril hydrochloride | 86541-74-4 | CGS14824A | 99.96% | C24H29ClN2O5 | 1 ML
Benazepril hydrochloride is an orally active angiotensin-converting enzyme (ACE) inhibitor that reduces angiotensin-II production. It inhibits oxidative stress and apoptosis via the PI3K/Akt signaling pathway. This compound can be used in studies of hypertension, heart failure, and diabetic nephropathy.
- Targets angiotensin-converting enzyme (ACE), apoptosis, Akt, and reactive oxygen species
- Reduces angiotensin-II production
- Inhibits oxidative stress and apoptosis through PI3K/Akt signaling pathway
- Improves diabetic nephropathy and decreases proteinuria
Apexbio Technology LLC Raloxifene HCl 82640-04-8 100mg
Raloxifene HCl (82640-04-8) is a selective estrogen receptor (ER) modulator targeting estrogen receptors and human liver cytosolic aldehyde oxidase It is designed to modulate ER and aldehyde oxidase activities thereby regulating estrogen signaling and oxidative metabolic pathways Raloxifene HCl exerts its biological activity primarily through noncompetitive inhibition of estrogen receptors and aldehyde oxidase-mediated reactions In in vitro studies Raloxifene HCl demonstrates inhibitory activity on human liver cytosolic aldehyde oxidase with IC50 values ranging from 2 9 to 5 7 nM and Ki values of 0 87 1 4 nM for oxidative reactions and 52 nM for reduction reactions Based on these pharmacological properties Raloxifene HCl holds research potential in investigating ER signaling pathways enzyme inhibition and metabolic processes in vitro