Drug Standards
Apexbio Technology LLC Imatinib (STI571) 152459-95-5 100mg
Imatinib (STI571) (CAS 152459-95-5) is a small-molecule inhibitor targeting protein tyrosine kinases including Abl kinase platelet-derived growth factor receptor (PDGFR) and c-Kit It modulates kinase activity by inhibiting phosphorylation thereby regulating oncogenic signal transduction pathways Imatinib exerts its biological activity primarily by suppressing the phosphorylation activity of Abl kinase (IC50 0 025 M) PDGFR (IC50 0 1 M) and c-Kit (IC50 0 1 M) In cell-based assays Imatinib inhibits PDGFR phosphorylation induced by PDGF-AA and PDGF-BB and reduces c-Kit-mediated signal transduction involved in tumor cell proliferation Based on these pharmacological properties Imatinib holds research potential in oncology for investigating kinase-driven cellular processes and therapeutic interventions
Medchemexpress LLC Atazanavir sulfate | 229975-97-7 | 802.93 | 1 ML
Atazanavir (BMS-232632) is a highly selective and orally active HIV-1 protease inhibitor. It acts as a substrate and inhibitor of CYP3A4, and an inhibitor of P-glycoprotein (P-gp). Atazanavir also inhibits SARS-CoV 3CL pro with an IC50 of 3.49 μM. Additionally, Atazanavir has been shown to inhibit cardiac fibrosis, hyperlipidemia, and induce malignant glioma cell death.
- Highly selective HIV-1 protease inhibitor
- Orally active
- Inhibits CYP3A4
- Inhibits P-glycoprotein (P-gp)
- Inhibits SARS-CoV 3CL pro
- Inhibits cardiac fibrosis
- Inhibits hyperlipidemia
- Induces malignant glioma death
![Alkali Scientific Folic Acid [Pteroylglutamic acid] [Vitamin M], 5 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661364.jpg-250.jpg)
Alkali Scientific Folic Acid [Pteroylglutamic acid] [Vitamin M], 5 G
Folic Acid (Pteroylglutamic acid), also known as Vitamin B9, is a compound used in cell culture applications, supplied in a 5g quantity. Folic acid is essential for DNA synthesis, repair, and cellular division, making it a vital component in maintaining cell growth and function. In cell culture, folic acid is typically used to support the growth and proliferation of eukaryotic cells, particularly in mammalian cell culture systems. It is also utilized in research related to gene expression, cellular metabolism, and the study of folate metabolism in various biological systems. The 5g packaging is ideal for laboratories requiring consistent and stable folic acid supplementation in their cell culture medium.
Medchemexpress LLC 2,3,4,6-tetra-O-pivaloyl-alpha-D-glucopyranosyl bromide | 81058-27-7 | MFCD08275217 | 50g
Empagliflozin impurity 15 is an impurity of Empagliflozin (HY-15409)
Medchemexpress LLC Iopamidol | 60166-93-0 | 99.9% | 100 MG
Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) primarily used for various diagnostic applications. It features amide and hydroxyl functionalities, which can be leveraged to generate chemical exchange saturation transfer (CEST) contrast. This product is intended for research use only.
- Nonionic, X-Ray iodinated contrast agent
- Utilized for various diagnostic applications
- Contains amide and hydroxyl functionalities
- Can generate chemical exchange saturation transfer (CEST) contrast
![Medchemexpress LLC 1-propanone, 1,3-bis[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl] | 1987905-93-0 | 5mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000266904.png-250.jpg)
Medchemexpress LLC 1-propanone, 1,3-bis[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl] | 1987905-93-0 | 5mg
Imatinib impurity 2 is an impurity of Imatinib (HY-15463)
Medchemexpress LLC Meta-fexofenadine | 479035-75-1 | MFCD21363595 | 98.6% | 501.66 | C32H39NO4 | 1 MG
Meta-fexofenadine is an analytical standard representing an impurity of fexofenadine, provided as an off-white to light-yellow solid for research and analytical applications. It is intended for use in pharmaceutical impurity profiling, analytical method development, and as a reference material; key chemical identifiers include CAS 479035-75-1, molecular formula C32H39NO4, and molecular weight 501.66.
- Purity 98.6% for reliable analytical reference.
- Supplied in small package sizes suitable for laboratory use.
- Solid form with off-white to light yellow appearance.
- Stable under recommended storage conditions for long-term use.
- Suitable for impurity profiling and method validation.
Medchemexpress LLC 1H-Benzimidazole, 6-bromo-4-fluoro-2-methyl-1-(1-methylethyl)- | 1231930-33-8 | 99.4% | C11H12BrFN2 | 10 G
Abemaciclib Impurity 1 is a drug intermediate used in the synthesis of various active compounds. It is supplied as an off-white to yellow solid for research use only.
- High purity (99.4%)
- Suitable for drug intermediate synthesis
- Stable as powder for 3 years at -20°C
- Stable as powder for 2 years at 4°C
- Stable in solvent for 6 months at -80°C
- Stable in solvent for 1 month at -20°C
Medchemexpress LLC Berberine ursodeoxycholate | 1868138-66-2 | 99.3% | 727.93 | 1 ML
Berberine ursodeoxycholate (HTD1801) is an orally active, potent hypolipidemic agent. As an ionic salt of Berberine and Ursodeoxycholic acid, it significantly reduces liver fat content and exhibits broad metabolic activity. It is researched for conditions like hyperlipidemia, non-alcoholic steatohepatitis (NASH), and diabetes.
- Orally active and potent hypolipidemic agent.
- Shows significantly great reduction in liver fat content.
- Has a broad spectrum of metabolic activity.
- Can be used for the research of hyperlipidemia, non-alcoholic steatohepatitis (NASH) and diabetes.
- Shows significant reductions in HbA1c (hemoglobin A1c) levels.
- Promptly dissociates within the gastrointestinal tract, allowing differential absorption of Berberine and Ursodeoxycholic acid.
Medchemexpress LLC Metoclopramide hydrochloride hydrate | 54143-57-6 | 99.96% | 354.27 | 500 MG
Metoclopramide hydrochloride hydrate is a potent antagonist of the 5-HT3 and dopamine D2 receptors, with IC50 values of 308 nM and 483 nM, respectively. It is used in research related to nausea, vomiting, gastro-oesophageal reflux, and gastroparesis. This product is for research use only and is not sold to patients.
- Potent antagonist of 5-HT3 and dopamine D2 receptors.
- Can be used for research on nausea and vomiting, gastro-oesophageal reflux, and gastroparesis.
Medchemexpress LLC Peramivir trihydrate | 1041434-82-5 | 98.3% | 382.45 | 25 MG
Peramivir trihydrate is a highly potent, selective, and orally active influenza virus neuraminidase (NA) inhibitor. It is intended for research use only.
- Highly potent and selective influenza virus neuraminidase (NA) inhibitor
- Has IC50 values ranging from 0.9 to 4.3 nM for nine NA subtypes
- Exhibits no toxicity to macrophages at tested concentrations
- Inhibits cytokine release in LPS-induced hPBMCs
- Inhibits LPS-induced cytokine storm and attenuates acute lung injury in mice
- Prolongs survival in cytokine storm syndrome model mice
![Medchemexpress LLC 2-butenamide, n-[4-[(4-chloro-3-fluorophenyl)amino]-7-[(3S)-tetrahydro-3-furanyloxy]-6-quinazolinyl] | 2475094-87-0 | 5mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000267580.png-250.jpg)
Medchemexpress LLC 2-butenamide, n-[4-[(4-chloro-3-fluorophenyl)amino]-7-[(3S)-tetrahydro-3-furanyloxy]-6-quinazolinyl] | 2475094-87-0 | 5mg
Afatinib impurity 33 is an impurity of Afatinib (HY-10261)
Cayman Chemical NorfloxacIn-d5 10mg
An internal standard for the quantification of norfloxacin by GC- or LC-MS
Apexbio Technology LLC Meloxicam (Mobic) 71125-38-7 10mM (in 1mL DMSO)
Meloxicam (CAS 71125-38-7) commercially known as Mobic is a nonsteroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2) thereby interfering with prostaglandin synthesis and mitigating inflammation and pain Its pharmacological activity against COX-2 reduces symptoms associated with rheumatoid arthritis juvenile rheumatoid arthritis and osteoarthritis such as joint pain stiffness and swelling As a COX-2 preferential inhibitor meloxicam is widely utilized as a reference compound in biomedical research examining inflammatory signaling pathways and arthritis-related disease models