Acetylides

Medchemexpress LLC VQW-765 | 669770-29-0 | 99.6% | 294.39 | 25 MG

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VQW-765 (AQW-051) is a selective and orally active alpha-7 nicotinic acetylcholine receptor (α7-nAChR) agonist. It demonstrates anxiolytic-like effects in vivo and is suitable for research into anxiety disorders and acute performance anxiety.

• Selective and orally active α7-nAChR agonist.
• Demonstrates anxiolytic-like effects in vivo.
• Suitable for research on anxiety disorder and acute performance anxiety.
• Increases cognitive effect and learning/memory performance.

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STA PHARMACEUTICAL US LLC 2'-propargyl G(iBu) amidite | 5 g | CAS 171486-61-6 | MDL MFCD28976150

2'-propargyl G(iBu) amidite is a Amidite reagent (Subcategory: 2'-propargyl Series) sold by WuXi TIDES. Offered in 5 g. Store at -20 °C. SDS available for reference.

Specifications
- CAS: 171486-61-6
- MDL: MFCD28976150
- InChIKey: AGWGPRXHCUPJJO-VCGWOZLGSA-N
- Molecular Weight: 893.978761998
- Molecular Formula: C47H56N7O9P
- Purity: ≥95%
- Container Type: 100 mL Glass (Septum)
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 100.4 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(N=C(N6)NC(C(C)C)=O)=C(N=C5)C6=O)OCC#C)OCCC#N)C(C)C)C

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Medchemexpress LLC Propargyl-PEG8-NH2 | 1196732-52-1 | 98.0% | 10 G

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Propargyl-PEG8-NH2 is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a non-cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). This compound is a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Peg-based protac linker
• Non-cleavable adc linker
• Click chemistry reagent
• Contains an alkyne group
• Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)

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Medchemexpress LLC Propargyl-PEG6-NH2 | 1198080-04-4 | 99.7% | 5 G

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Propargyl-PEG6-NH2 is a PEG-based PROTAC linker that functions as a click chemistry reagent. It contains an Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups. This reagent is primarily used in the synthesis of PROTACs, which leverage the intracellular ubiquitin-proteasome system for selective degradation of target proteins.

• PEG-based PROTAC linker
• Utilized in the synthesis of PROTACs
• Functions as a click chemistry reagent
• Contains an Alkyne group
• Engages in copper-catalyzed azide-alkyne cycloaddition (CuAAc)
• Reacts with molecules possessing Azide groups

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Selegiline Hydrochloride, USP, 98-101%, Spectrum™ Chemical

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CAS: 14611-52-0 Molecular Formula: C13H18ClN Molecular Weight (g/mol): 223.74 MDL Number: MFCD00069299 InChI Key: IYETZZCWLLUHIJ-UTONKHPSSA-N IUPAC Name: hydrogen methyl[(2R)-1-phenylpropan-2-yl](prop-2-yn-1-yl)amine chloride SMILES: [H+].[Cl-].C[C@H](CC1=CC=CC=C1)N(C)CC#C

MP Biomedicals, Inc 1-Hexyn-3-ol, MP Biomedicals

CAS: 105-31-7 Molecular Formula: C6H10O Molecular Weight (g/mol): 98.145 InChI Key: LTFTWJYRQNTCHI-UHFFFAOYSA-N Synonym: 1-hexyn-3-ol,propylethinylcarbinol,1-hexyne-3-ol,3-hydroxy-1-hexyne,1-propylpropargyl alcohol,1-hexine-3-ol,acmc-2098fm,dsstox_cid_30088,dsstox_gsid_51536,4-01-00-02234 beilstein handbook reference PubChem CID: 7746 IUPAC Name: hex-1-yn-3-ol SMILES: CCCC(C#C)O

1,1-Diethylpropargylamine, 97%, Thermo Scientific™

CAS: 3234-64-8 Molecular Formula: C7H14N Molecular Weight (g/mol): 112.20 MDL Number: MFCD00008057 InChI Key: WHNOKDNCUNZBLW-UHFFFAOYSA-O Synonym: 1,1-diethylpropargylamine,1-pentyn-3-amine, 3-ethyl,1-pentyn-3-amine,3-ethyl,1,1-diethyl-prop-2-ynylamine,2,2-diethylpropargylamine,1,1-diethylproparagyl amine,3-ethyl-1-pentyn-3-amine,3-amino-3-ethyl-1-pentyne,1,1-diethyl-2-propynylamine,1,1-diethyl-2-propynylamine # PubChem CID: 76710 IUPAC Name: 3-ethylpent-1-yn-3-aminium SMILES: CCC([NH3+])(CC)C#C

3-Butyn-1-ol, 98+%, Thermo Scientific™

CAS: 927-74-2 Molecular Formula: C4H6O Molecular Weight (g/mol): 70.091 MDL Number: MFCD00002955 InChI Key: OTJZCIYGRUNXTP-UHFFFAOYSA-N Synonym: 3-butyn-1-ol,3-butynol,3-butyne-1-ol,4-hydroxy-1-butyne,3-butynyl alcohol,1-butyn-4-ol,2-hydroxyethylacetylene,homopropargyl alcohol,2-hydroxyethyl acetylene,4-hydroxy-butyne PubChem CID: 13566 ChEBI: CHEBI:27444 IUPAC Name: but-3-yn-1-ol SMILES: C#CCCO

N-Propargyloxyphthalimide, 97%, Thermo Scientific™

CAS: 4616-63-1 Molecular Formula: C11H7NO3 Molecular Weight (g/mol): 201.181 MDL Number: MFCD00005890 InChI Key: HBGZBVPXPDNXOV-UHFFFAOYSA-N Synonym: n-propargyloxy phthalimide,n-prop-2-ynyloxy phthalimide,2-prop-2-yn-1-yloxy isoindoline-1,3-dione,n-propargyloxyphthalimide,2-prop-2-yn-1-yloxy isoindole-1,3-dione,2-prop-2-ynyloxybenzo c azoline-1,3-dione,acmc-20aka8,n-2-propynoxyphthalimide,n-2-propynyloxy phthalimide,phthalimide, n-2-propynyloxy PubChem CID: 78357 IUPAC Name: 2-prop-2-ynoxyisoindole-1,3-dione SMILES: C#CCON1C(=O)C2=CC=CC=C2C1=O

1-Heptyn-3-ol, 98%, Thermo Scientific™

CAS: 7383-19-9 Molecular Formula: C7H12O Molecular Weight (g/mol): 112.172 MDL Number: MFCD00041597 InChI Key: SHSFXAVQBIEYMK-UHFFFAOYSA-N Synonym: 1-heptyn-3-ol,n-butyl ethynyl carbinol,acmc-1biv8,1-heptyn-3-ol, +/- PubChem CID: 93050 IUPAC Name: hept-1-yn-3-ol SMILES: CCCCC(C#C)O

1,6-Heptadiyne, Thermo Scientific™

CAS: 2396-63-6 Molecular Formula: C7H8 Molecular Weight (g/mol): 92.141 MDL Number: MFCD00014925 InChI Key: RSPZSDWVQWRAEF-UHFFFAOYSA-N Synonym: 1,6-heptadiyne,1,6-heptadiyne 6ci, 8ci, 9ci,heptane-1,6-diyne,acmc-1cin6,1,6-heptadiyne, 97+%,wln: 1uu5uu1,4-01-00-01121 beilstein handbook reference PubChem CID: 337121 IUPAC Name: hepta-1,6-diyne SMILES: C#CCCCC#C

5-Hexyn-3-ol 90.0+%, TCI America™

CAS: 19780-84-8 Molecular Formula: C6H10O Molecular Weight (g/mol): 98.145 MDL Number: MFCD00041593 InChI Key: AJYGRAORQSCNED-UHFFFAOYSA-N Synonym: 5-hexyn-3-ol,1-hexyn-4-ol,4-hydroxy-1-hexyne,4-hydroxy-1hexyne,acmc-1buup,ajygraorqscned-uhfffaoysa PubChem CID: 89223 IUPAC Name: hex-5-yn-3-ol SMILES: CCC(CC#C)O

3-Butyn-2-ol (55% in Water, ca. 7.5mol/L), TCI America™

CAS: 2028-63-9 Molecular Formula: C4H6O Molecular Weight (g/mol): 70.09 MDL Number: MFCD00004541 InChI Key: GKPOMITUDGXOSB-UHFFFAOYNA-N Synonym: 3-butyn-2-ol,3-butyne-2-ol,3-hydroxy-1-butyne,1-butyn-3-ol,1-methylpropargyl alcohol,methylethynylcarbinol,1-ethynylethanol,1-methyl-2-propynyl alcohol,alpha-methylpropargyl alcohol,dl-3-butyn-2-ol PubChem CID: 16239 IUPAC Name: but-3-yn-2-ol SMILES: CC(O)C#C

1-Undecyne 96.0+%, TCI America™

CAS: 2243-98-3 Molecular Formula: C11H20 Molecular Weight (g/mol): 152.281 MDL Number: MFCD00015063 InChI Key: YVSFLVNWJIEJRV-UHFFFAOYSA-N Synonym: 1-undecyne,rutylidene,unii-y07u3q24us,undecyne,acmc-1cr7r,1-undecyne 10g PubChem CID: 75249 ChEBI: CHEBI:87545 IUPAC Name: undec-1-yne SMILES: CCCCCCCCCC#C

5-Methyl-1-hexyn-3-ol 98.0+%, TCI America™

CAS: 61996-79-0 Molecular Formula: C7H12O Molecular Weight (g/mol): 112.172 MDL Number: MFCD00041606 InChI Key: NTNUBJHPRAMQPC-UHFFFAOYSA-N Synonym: 5-methyl-1-hexyn-3-ol,acmc-209myn,5-methyl-hex-1-yn-3-ol,1-hexyn-3-ol,5-methyl,1-hexyn-3-ol, 5-methyl PubChem CID: 143856 IUPAC Name: 5-methylhex-1-yn-3-ol SMILES: CC(C)CC(C#C)O