Hydrochlorides
Medchemexpress LLC 1-(4-methoxybenzyl)-5-trifluoromethoxyisatin | 1160247-92-6 | 99.9% | 25 MG
VU 0238429 is a research-grade positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5). In vitro it shows an EC50 of 1.16 μM and >30-fold selectivity versus M1 and M3, with no potentiation of M2 or M4. Supplied as a high-purity solid or as DMSO solutions, it is intended for laboratory research use.
- Positive allosteric modulator of mAChR5.
- In vitro potency EC50 1.16 μM.
- Greater than 30-fold selectivity versus M1 and M3.
- High purity (≈99.9%).
- Available as solid or 10 mM solution in DMSO.
- Recommended storage: powder -20°C; in solvent -80°C for long-term.
Medchemexpress LLC Benzamide, 4-butoxy-N-(2,4-difluorophenyl)- | 433967-28-3 | C17H17F2NO2 | 25 MG
VU 0357121 is a positive and highly selective mGlu5R allosteric modulator (PAM) with an EC50 of 33 nM. It is inactive or exhibits very weak antagonizing effects at other mGlu receptor subtypes.
- Highly selective mGlu5R allosteric modulator (PAM)
- EC50 of 33 nM
- Inactive or very weakly antagonizing at other mGlu receptor subtypes
- Enhances glutamate sensitivity of mGlu5
- Does not bind at the MPEP allosteric site of mGlu5
- Used for research purposes only
Medchemexpress LLC 4-amino-3-phenylbutanoic acid hydrochloride | 3060-41-1 | 98.0% | 215.68 g/mol | C10H14ClNO2 | 50 G
Phenibut hydrochloride is the hydrochloride salt of β-phenyl-GABA, a GABAB receptor agonist used as a research chemical to study GABAergic signaling. It is supplied as a solid powder with typical analytical purity around 98.0%.
- GABAB receptor agonist for neuropharmacology research
- High purity (98.0%) suitable for analytical use
- Solid powder form, easy to weigh and dissolve
- Commonly used in studies of anxiolytic and cognitive effects
- Available in multiple pack sizes, including 50 g
Apexbio Technology LLC Nitrocaramiphen hydrochloride 98636-73-8 10mg
Nitrocaramiphen hydrochloride (CAS 98636-73-8) is a small molecule that acts as a selective antagonist of muscarinic acetylcholine M1 receptors exhibiting a Ki of 5 5 nM Studies indicate that it effectively inhibits the hyperpolarizing effects induced by muscarinic agonists in muscle fibers Due to its receptor specificity nitrocaramiphen hydrochloride is widely utilized in neurobiological research to investigate cholinergic signaling pathways and the physiological roles of M1 receptor modulation
Medchemexpress LLC Numidargistat dihydrochloride | 98.5% | 360.04 g·mol^-1 | C11H24BCl2N3O5 | 100 MG
Numidargistat dihydrochloride is a research-grade small-molecule inhibitor of arginase used in preclinical immunology and oncology studies. It displays nanomolar activity against recombinant human arginase enzymes and is supplied as the dihydrochloride salt with manufacturer guidance for storage and batch-specific purity.
- Potent inhibition of arginase 1 and 2 (IC50 ≈ 86 nM and 296 nM)
- Orally bioavailable profile suitable for in vivo dosing in preclinical models
- Suitable for in vitro biochemical and cell-based assays
- Dihydrochloride salt form improves solubility and handling
- Supplied with batch COA and storage recommendations for research use only
![eMolecules 35478-79-6 | [1,3]Dioxolo[4,5-g]quinolin-8-ol | J & W PharmLab LLC | MFCD22395081 | 189.170 | C10H7NO3 | 95.000 | Oc1ccnc2cc3OCOc3cc12 | 1g | 456105793](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502147440.JPG-250.jpg)
eMolecules 35478-79-6 | [1,3]Dioxolo[4,5-g]quinolin-8-ol | J & W PharmLab LLC | MFCD22395081 | 189.170 | C10H7NO3 | 95.000 | Oc1ccnc2cc3OCOc3cc12 | 1g | 456105793
[1,3]Dioxolo[4,5-g]quinolin-8-ol | J & W PharmLab LLC | 35478-79-6 | MFCD22395081 | 189.170 | C10H7NO3 | 95.000 | Oc1ccnc2cc3OCOc3cc12 | 1g | 456105793
Medchemexpress LLC Zt 52656a hydrochloride | 115730-24-0 | 99.98% | 390.87 | C19H26ClF3N2O | 10 MG
ZT 52656A hydrochloride is the hydrochloride salt of a selective kappa-opioid receptor agonist used in research on kappa opioid receptor pharmacology. It is reported for prevention or alleviation of ocular pain and is supplied for in vitro and in vivo experimental use.
- Selective kappa-opioid receptor agonist, useful for KOR pharmacology studies.
- High reported purity of 99.98% for consistent experimental results.
- Chemical formula C19H26ClF3N2O and molecular weight 390.87 aid in dosing and calculations.
- Available in multiple pack sizes and as a DMSO solution for flexible experimental use.
- Provided as the hydrochloride salt to improve solubility in aqueous media.
![Medchemexpress LLC 5-isoxazoleacetic acid, a-amino-3-chloro-4,5-dihydro-, monohydrochloride, [S-(R*,R*)]- | 161922-40-3 | MFCD32874156 | 99.1% | 215.03 g·mol⁻¹ | C5H8Cl2N2O3 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000303494.png-250.jpg)
Medchemexpress LLC 5-isoxazoleacetic acid, a-amino-3-chloro-4,5-dihydro-, monohydrochloride, [S-(R*,R*)]- | 161922-40-3 | MFCD32874156 | 99.1% | 215.03 g·mol⁻¹ | C5H8Cl2N2O3 | 25 MG
Acivicin hydrochloride is the hydrochloride salt of acivicin, a natural product γ-glutamyl transpeptidase (GGT) inhibitor used as a biochemical research reagent. It is supplied as a solid and in solution formats for laboratory use, with defined storage conditions to preserve stability and activity.
- High confirmed purity (HPLC): 99.1%.
- Molecular weight 215.03 g·mol⁻¹ and formula C5H8Cl2N2O3.
- Available in mg-scale packs and solution aliquots for assay flexibility.
- Suitable for biochemical studies targeting GGT and related pathways.
- Storage recommendations: 4°C under nitrogen; in solvent -80°C (6 months) or -20°C (1 month).
eMolecules 21987-29-1 | 4,4-Difluoropiperidine | ChemScene | MFCD03094281 | 121.131 | C5H9F2N | 97.000 | FC1(F)CCNCC1 | 1g | 569143771
4,4-Difluoropiperidine | ChemScene | 21987-29-1 | MFCD03094281 | 121.131 | C5H9F2N | 97.000 | FC1(F)CCNCC1 | 1g | 569143771
Medchemexpress LLC Roxindole hydrochloride | 108050-82-4 | 99.0% | 382.93 g/mol | C23H27ClN2O | 1 ML
Roxindole hydrochloride is a research chemical acting as a dopamine autoreceptor agonist and a 5-HT1A receptor agonist with reported antipsychotic and antidepressant activity. It is intended for laboratory research and analytical use and is supplied in solution and solid forms with accompanying documentation for traceability and safety.
Medchemexpress LLC Idazoxan hydrochloride | 79944-56-2 | MFCD00069293 | 99.32% | C11H13ClN2O2 | 1 ML
Idazoxan hydrochloride is a compound that acts as an α2-adrenoceptor antagonist and an imidazoline receptors antagonist. It is known for its ability to competitively antagonize the centrally induced hypotensive effect of imidazoline-like agents. Research indicates its potential to improve motor symptoms associated with Parkinson's disease, L-DOPA-induced dyskinesias, and experimental Parkinsonism.
- Acts as an α2-adrenoceptor antagonist
- Functions as an imidazoline receptors antagonist
- Competitively antagonizes centrally induced hypotensive effects
- Potential to improve motor symptoms in Parkinson's disease
- Potential to improve L-DOPA-induced dyskinesias
- Potential to improve experimental Parkinsonism
- Reverses haloperidol-induced catalepsy in rat models
eMolecules 1181556-77-3 | 1,2-Ethanediamine, N,N-dimethyl-N'-(tetrahydro-1,1-dioxido-3-thienyl)-, dihydrochloride | Combi-Blocks, Inc. | MFCD06682713 | 279.220 | C8H20Cl2N2O2S | 95.000 | Cl.Cl.CN(C)CCNC1CCS(=O)(=O)C1 | 1g | 586076681
1,2-Ethanediamine, N,N-dimethyl-N'-(tetrahydro-1,1-dioxido-3-thienyl)-, dihydrochloride | Combi-Blocks, Inc. | 1181556-77-3 | MFCD06682713 | 279.220 | C8H20Cl2N2O2S | 95.000 | Cl.Cl.CN(C)CCNC1CCS(=O)(=O)C1 | 1g | 586076681
Medchemexpress LLC VU0360172 hydrochloride | 1309976-62-2 | 98.9% | 330.78 | C18H16ClFN2O | 5 MG
VU0360172 hydrochloride is a potent, selective positive allosteric modulator (PAM) of the metabotropic glutamate receptor 5 (mGlu5). It potentiates mGlu5 signaling (EC50 = 16 nM; Ki = 195 nM) and is supplied as a white to off-white solid for research use. Typical applications include receptor pharmacology, cellular signaling assays, and in vivo pharmacology studies.
- Potent mGlu5 PAM activity (EC50 16 nM).
- Confirmed binding affinity (Ki 195 nM).
- High purity suitable for research (98.9%).
- Molecular weight 330.78 for accurate dosing and calculations.
- Solid form, white to off-white, for convenient handling and storage.
- Recommended storage: store sealed at -20°C; in solution, -80°C for long term.
- Supplied in small research pack sizes appropriate for pilot studies.
eMolecules 51285-26-8 | Picolinimidamide hydrochloride | ChemScene | MFCD00052271 | 157.600 | C6H8ClN3 | 95.000 | Cl.NC(=N)c1ccccn1 | 5g | 789369249
Picolinimidamide hydrochloride | ChemScene | 51285-26-8 | MFCD00052271 | 157.600 | C6H8ClN3 | 95.000 | Cl.NC(=N)c1ccccn1 | 5g | 789369249
eMolecules 21987-29-1 | 4,4-Difluoropiperidine | Combi-Blocks, Inc. | MFCD03094281 | 121.131 | C5H9F2N | 98.000 | FC1(F)CCNCC1 | 25g | 794200203
4,4-Difluoropiperidine | Combi-Blocks, Inc. | 21987-29-1 | MFCD03094281 | 121.131 | C5H9F2N | 98.000 | FC1(F)CCNCC1 | 25g | 794200203