Hydrochlorides
eMolecules BENZYL 1-BENZYL-4-METHYLPIPERAZINE-2-CARBOXYLATE | 1447605-99-3 | MFCD09037846 | 1g
AstaTech | BENZYL 1-BENZYL-4-METHYLPIPERAZINE-2-CARBOXYLATE | 1g | 437210116 | AB2647 | 95.000 | 1447605-99-3 | MFCD09037846 | 324.424 | C20H24N2O2
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Medchemexpress LLC IACS-9571 hydrochloride | 2319611-93-1 | 98.3% | 679.22 g/mol | C32H43ClN4O8S | 10 MG
IACS-9571 hydrochloride is a selective, low-nanomolar inhibitor of the TRIM24 and BRPF1 bromodomains used as a research tool to probe bromodomain biology and epigenetic regulation. It is supplied as the hydrochloride salt and is characterized by low-nanomolar binding (IC50 ≈ 8 nM for TRIM24; Kd values in the low nanomolar range for TRIM24 and BRPF1).
- Selective dual TRIM24/BRPF1 bromodomain inhibition
- Low-nanomolar potency (IC50 ≈ 8 nM)
- High purity suitable for research (~98.3%)
- Available in small research pack sizes for in vitro work
- Offered as solid and as 10 mM solutions in DMSO
eMolecules 21987-29-1 | 4,4-Difluoropiperidine | Combi-Blocks, Inc. | MFCD03094281 | 121.131 | C5H9F2N | 98.000 | FC1(F)CCNCC1 | 25g | 794200203
4,4-Difluoropiperidine | Combi-Blocks, Inc. | 21987-29-1 | MFCD03094281 | 121.131 | C5H9F2N | 98.000 | FC1(F)CCNCC1 | 25g | 794200203
Medchemexpress LLC Pazopanib hydrochloride | 635702-64-6 | 100.0% | 100MG
Pazopanib hydrochloride | 635702-64-6 | 100.0% | 100MG
Medchemexpress LLC Rb-opd (NO-red) | 1034863-51-8 | 95.0% | 532.68 | C34H36N4O2 | 10 MG
RB-OPD (NO-red) is an o-phenylenediamine (OPD)-locked rhodamine-based fluorescent probe for selective and sensitive detection of nitric oxide in biochemical assays and imaging. It has excitation/emission maxima at 550 nm and 590 nm and is supplied as a solid or as a DMSO solution for research use only.
- Selective detection of nitric oxide via spiro ring opening mechanism.
- Excitation/emission: 550 nm/590 nm, compatible with common fluorescence setups.
- High reported purity (95.0%), suitable for research assays.
- Available as solid (small mg quantities) or as a 10 mM solution in dimethyl sulfoxide (DMSO).
- Compact quantities support small-scale imaging and assay workflows.
Medchemexpress LLC preQ1 dihydrochlorid 100mg | 86694-45-3 | 252.10 g/mol | C7H11Cl2N5O | 100 MG
preQ1 dihydrochloride is the dihydrochloride salt of pre-queuosine 1, a guanine-derived nucleobase that serves as a direct precursor in queuine biosynthesis. It binds with high affinity to the PreQ1 riboswitch aptamer and is provided for biochemical and molecular biology research (research use only).
- Precursor in queuine biosynthesis and riboswitch studies.
- Molecular formula C7H11Cl2N5O; molecular weight 252.10 g/mol.
- Purity 98.88% as supplied.
- Soluble in DMSO (125 mg/mL) and water (14.29 mg/mL with warming).
- Appearance solid, white to light brown.
- Available in small research quantities (1 mg-500 mg).
Medchemexpress LLC Duloxetine | 116539-59-4 | 99.9% | 25 MG
Duloxetine, also known as LY248686, is a potent serotonin-norepinephrine reuptake inhibitor with a Ki of 4.6 nM. It is primarily utilized in research for its role in treating major depressive disorder and generalized anxiety disorder (GAD). This compound selectively inhibits the reuptake of serotonin and norepinephrine within the central nervous system, demonstrating less potency in inhibiting dopamine reuptake. It is intended for research use only and not for patient administration.
- Serotonin-norepinephrine reuptake inhibitor
- Used for major depressive disorder research
- Used for generalized anxiety disorder research
- Selective reuptake inhibitor at 5-HT and NA transporters
- No significant affinity for various other receptors (dopaminergic, adrenergic, cholinergic, histaminergic, opioid, glutamate, GABA)
![Medchemexpress LLC 1H-indol-5-ol, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl] hydrochloride | 108050-82-4 | 99.0% | 382.93 g/mol | C23H27ClN2O | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000243157.png-250.jpg)
Medchemexpress LLC 1H-indol-5-ol, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl] hydrochloride | 108050-82-4 | 99.0% | 382.93 g/mol | C23H27ClN2O | 100 MG
Roxindole hydrochloride is the hydrochloride salt of roxindole (EMD 38362), a research tool compound investigated as a dopamine autoreceptor (D2-like) agonist and a 5-HT1A agonist that also inhibits serotonin uptake. It is used in vitro and in vivo to study dopaminergic and serotonergic signaling and to model psychiatric disorder pharmacology.
- High purity (99.0%) suitable for analytical and research use.
- Molecular weight 382.93 g/mol for accurate dosing calculations.
- Hydrochloride salt form to improve solubility in polar solvents.
- Appropriate for in vitro and in vivo pharmacology studies.
- Provided in milligram quantities to support small-scale experiments.
eMolecules 1261471-73-1 | 3-(TRIFLUOROMETHYL)QUINOLIN-7-OL | MFCD18417204 | 1g
Medchem Express | ML337 | 5mg | 784544249 | HY-16636 | 1443118-44-2 | MFCD27937770 | 353.393 | C21H20FNO3
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Medchemexpress LLC N-(1,3-diphenyl-1H-pyrazolo-5-yl)-4-nitrobenzamide | 890764-36-0 | MFCD12546140 | 99.6% | 384.39 g·mol⁻¹ | C22H16N4O3 | 50 MG
VU-29 is a research-grade small molecule that functions as a positive allosteric modulator of the metabotropic glutamate receptor 5 (mGlu5). It is provided as a purified solid for preclinical and in vitro pharmacology studies and assay development.
- Acts as a positive allosteric modulator of mGlu5 receptor.
- Reported EC50 ≈ 9 nM for rat mGlu5 and Ki ≈ 244 nM for the MPEP allosteric site.
- High purity (~99.6%) suitable for analytical and pharmacological assays.
- Molecular formula C22H16N4O3 and molecular weight 384.39 g·mol⁻¹.
- Intended for research use only, not for human or veterinary applications.
- Available in small-scale pack sizes for assay development and screening.
Medchemexpress LLC Biotin-PEG4-picolyl azide | 2222687-71-8 | MFCD29052186 | 98.7% | C27H42N8O7S | 10MG
Biotin-PEG4-picolyl azide is a biotinylated PEG linker with a picolyl azide group designed for click chemistry and biochemical workflows. It participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), and the biotin moiety enables affinity capture, detection, and purification in assays.
- Enables CuAAC reactions with alkyne-containing molecules.
- Compatible with SPAAC reactions using DBCO or BCN partners.
- Provides a biotin affinity tag for capture and detection workflows.
- PEG4 spacer improves solubility and reduces steric hindrance.
- High purity suitable for biochemical applications.
Medchemexpress LLC Lobeline hydrochloride | 134-63-4 | 99.9% | 5 MG
Lobeline (α-Lobeline) hydrochloride is a brain-penetrant nicotinic receptor agonist. It increases dopamine (DA) release by inhibiting DA uptake into synaptic vesicles and altering presynaptic DA storage. Lobeline hydrochloride is effective in smoking cessation.
- Evokes [3H]DA overflow calcium-independently
- Inhibits [3H]DA uptake into synaptosomes and vesicles
- Decreases d-methamphetamine self-administration in rats
- Increases tolerance development to d-methamphetamine
Medchemexpress LLC 4-amino-3-phenylbutanoic acid hydrochloride | 3060-41-1 | 98.0% | 215.68 g/mol | C10H14ClNO2 | 50 G
Phenibut hydrochloride is the hydrochloride salt of β-phenyl-GABA, a GABAB receptor agonist used as a research chemical to study GABAergic signaling. It is supplied as a solid powder with typical analytical purity around 98.0%.
- GABAB receptor agonist for neuropharmacology research
- High purity (98.0%) suitable for analytical use
- Solid powder form, easy to weigh and dissolve
- Commonly used in studies of anxiolytic and cognitive effects
- Available in multiple pack sizes, including 50 g
Medchemexpress LLC PS372424 hydrochloride | 1596362-29-6 | ≥98.0% | 625.20 | 10 MG
PS372424 hydrochloride, a three amino-acid fragment of CXCL10, is a specific human CXCR3 agonist with anti-inflammatory activity. It prevents human T-cell migration in a humanized model of arthritic inflammation.
- Specific human CXCR3 agonist
- Anti-inflammatory activity
- Prevents human T-cell migration in a humanized model of arthritic inflammation
- For research use only
Medchemexpress LLC Queuine dihydrochloride | 86496-18-6 | 97.3% | 350.20 g·mol-1 | C12H17Cl2N5O3 | 10 MG
Queuine dihydrochloride is the dihydrochloride salt of queuine, a modified nucleobase that serves as a substrate for tRNA guanine transglycosylase (TGT). It is used in research to study tRNA modification, mitochondrial function, and metabolic regulation in models of cancer and autoimmune disease.
- Selective substrate for tRNA guanine transglycosylase (TGT).
- Facilitates study of tRNA modification and effects on mitochondrial function and metabolism.
- Useful in research on cancer metabolism and autoimmune disease models.
- Available in small research quantities (e.g. 10 MG) for laboratory experiments.
- Reported purity approximately 97.3% and molecular weight 350.20 g·mol-1.