Hydrochlorides
Selleck Chemical LLC VU-29 S1970-25mg
VU-29 is a positive allosteric modulator of metabotropic glutamate 5 (mGlu5) receptor with EC50 of 9 nM and Ki 244 nM for rat mGluR5 which is selective for mGluR5 relative to other mGluR subtypes
Chem-Impex International, Inc. Cysteamine hydrochloride | 156-57-0 | MFCD00012904 | 100G
Cysteamine hydrochloride, 156-57-0, MFCD00012904, 100G
Chem-Impex International, Inc. 2-Picolyl chloride hydrochloride | 6959-47-3 | MFCD00012811 | 25G
2-Picolyl chloride hydrochloride, 6959-47-3, MFCD00012811, 25G
Chem-Impex International, Inc. 2-Picolyl chloride hydrochloride | 6959-47-3 | MFCD00012811 | 250G
2-Picolyl chloride hydrochloride, 6959-47-3, MFCD00012811, 250G
Sigma Aldrich Fine Chemicals Biosciences Cysteamine hydrochloride BioXtra | 156-57-0 | MFCD00012904 | 100G
Cysteamine hydrochloride BioXtra | Mol Wt: 113.61 | 156-57-0 | MFCD00012904 | 100G
Medchemexpress LLC PD 128907 hydrochloride | 112960-16-4 | 99.5% | 285.77 g/mol | C14H20ClNO3 | 50 MG
PD 128907 hydrochloride is a selective dopamine D3 receptor agonist used as a biochemical reagent for life-science research. It exhibits sub-nanomolar potency at D3 receptors (EC50 ~0.64 nM) and substantial selectivity over D2 receptors, and is supplied as a high-purity solid for in vitro pharmacology and receptor-binding studies.
- Potent D3 receptor agonist with EC50 ~0.64 nM.
- High selectivity over D2 receptors (≈53-fold).
- Reported high purity suitable for research use.
- Available in small package sizes for experimental workflows.
- Applicable to dopaminergic signaling and receptor pharmacology studies.
Medchemexpress LLC CP-24879 hydrochlori 1mg | 10141-51-2 | 215.72 | 1 MG
CP-24879 hydrochloride is a small-molecule research reagent that functions as a potent and selective combined delta5-desaturase/delta6-desaturase (Δ5/Δ6) inhibitor. It reduces intracellular lipid accumulation and inflammatory injury in hepatocyte models and is used in studies of fatty acid metabolism and non-alcoholic steatohepatitis. This compound is supplied for laboratory research use only.
- Potent combined Δ5/Δ6 desaturase inhibition
- Applied in lipid metabolism and NASH research
- High purity (99.59% by LCMS)
- Solid, off-white to light brown appearance
- Available in small research quantities (for example, 1 mg)
Medchemexpress LLC PND-1186 hydrochloride | 1356154-94-3 | 99.9% | 537.96 | 25 MG
PND-1186 hydrochloride is a potent, highly-specific, and reversible inhibitor of FAK with an IC50 of 1.5 nM. It selectively promotes tumor cell apoptosis.
- Potent, highly-specific, and reversible inhibitor of FAK
- Selectively promotes tumor cell apoptosis
- Inhibits FAK Tyr-397 phosphorylation
- Elevates total FAK protein levels
- Inhibits 4T1 subcutaneous tumor growth
- Induces apoptosis in BALB/c mice
Medchemexpress LLC Lobeline hydrochloride | 134-63-4 | 99.97% | 250 MG
Lobeline hydrochloride is a brain-penetrant nicotinic receptor agonist that increases dopamine (DA) release by inhibiting DA uptake into synaptic vesicles and altering presynaptic DA storage. It is effective in smoking cessation.
- Acts as a brain-penetrant nicotinic receptor agonist
- Increases dopamine release by inhibiting dopamine uptake
- Alters presynaptic dopamine storage
- Effective in smoking cessation
- Appears as a white to off-white solid
- Purity is 99.97%
Medchemexpress LLC EG01377 dihydrochloride | 2749438-61-5 | 99.0% | 659.60 | 1 ML
EG01377 dihydrochloride is a potent, bioavailable, and selective inhibitor of neuropilin-1 (NRP1), with a Kd of 1.32 μM, and IC50s of 609 nM for both NRP1-a1 and NRP1-b1. It exhibits antiangiogenic, antimigratory, and antitumor effects.
- Inhibits vascular endothelial growth factor A (VEGF-A) stimulated tyrosine phosphorylation of VEGF-R2/KDR.
- Reduces HUVEC cell migration in response to VEGFA.
- Can delay VEGF-induced wound closure.
- Reduces network area, length, and branching points.
- Reduces VEGF-induced angiogenesis.
- Reduces A375P (malignant melanoma) spheroid outgrowth in combination with VEGFA.
- Blocks the production of transforming growth factor beta (TGFβ) by Nrp1+ regulatory T-cell SMAD3/AKT (Tregs) in the presence of tumor cell-derived factors.
- Exhibits an encouraging half-life sufficient to sustain once per day dosing in mice.
Medchemexpress LLC Ly-2365109 hydrochloride | 1779796-27-8 | 98.7% | 421.91 g·mol^-1 | C22H28ClNO5 | 100 MG
LY2365109 hydrochloride is a research-grade small molecule and selective inhibitor of the glycine transporter 1 (GlyT1). Supplied as the hydrochloride salt for laboratory research use, it has been characterized in cell-based glycine uptake assays and is intended for in vitro pharmacology and transporter studies.
- Potent, selective GlyT1 inhibition (IC50 15.8 nM).
- High purity suitable for research (≈98.7%).
- Hydrochloride salt form for improved handling and solubility.
- Molecular weight consistent with salt form (≈421.9 g·mol⁻¹).
- Suitable for in vitro pharmacology and transporter profiling.
Medchemexpress LLC Bestatin hydrochloride | 65391-42-6 | 99.94% | 5 MG
Bestatin hydrochloride is a chemical compound known for its role as a competitive inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase. It is utilized in cancer research and is available with a high purity of 99.94%. This product is intended for research use only.
- Inhibitor of CD13 (Aminopeptidase N)/APN
- Inhibitor of leukotriene A4 hydrolase
- Used for cancer research
- Enhances ATRA-induced differentiation
- Inhibits ATRA-driven phosphorylation of p38 MAPK
- Solid, white to off-white appearance
- Store at 4°C under nitrogen
Matrix Scientific 4-(CHLOROMETHYL)PYRIDINEHY-25G
4-(Chloromethyl)pyridinehydrochloride, 98%; 25g,C6H7Cl2N, MFCD00012826, mw 164.04, [1822-51-1]
Medchemexpress LLC Iso-H7 dihydrochloride | 140663-38-3 | 99.1% | 364.29 | 1 MG
Iso-H7 dihydrochloride is a protein kinase inhibitor. It exhibits IC50 values of 22 μM for Protein Kinase C (PKC) and 34 μM for Protein Kinase A (PKA). This compound has been observed to have a negative control effect on PKA in the context of satellite cell myogenesis.
- Potent inhibitor of protein kinases, specifically PKC and PKA.
- Demonstrates inhibitory activity against PKC with an IC50 of 22 μM.
- Inhibits PKA with an IC50 of 34 μM.
- Exerts negative control over PKA's role in satellite cell myogenesis.
- Suitable for research applications.