Hydrochlorides
Medchemexpress LLC TP0427736 hydrochloride | 2459963-17-6 | 99.2% | 334.85 | C14H11ClN4S2 | 25 MG
TP0427736 hydrochloride is a research-grade small-molecule inhibitor of ALK5 (TGF-β type I receptor), provided as the hydrochloride salt with characterized purity, molecular weight, solubility, and storage recommendations. It is intended for biochemical and cellular studies of TGF-β/Smad signaling.
- High purity (>99%) suitable for research applications.
- Potent ALK5 inhibition with low-nanomolar IC50 values.
- Available in milligram pack sizes for assay development and screening.
- Soluble in water and DMSO with published solubility conditions.
- Stored under low-temperature conditions to preserve stability.
Selleck Chemical LLC VU 0357121 S2795-10mg
VU0357121 is a novel positive allosteric modulator (PAM) of mGlu5 with EC50 of 33 nM is inactive or very weakly antagonizing at other mGlu receptor subtypes
Medchemexpress LLC TP0427736 hydrochloride | 2459963-17-6 | 99.2% | 334.85 | C14H11ClN4S2 | 5 MG
TP0427736 hydrochloride is a potent ALK5 (TGF-β receptor I) kinase inhibitor supplied as the hydrochloride salt for laboratory research use. It has reported biochemical potency (IC50 2.72 nM), a molecular weight of 334.85 g/mol, and a reported purity of 99.22%.
- Potent ALK5 kinase inhibitor (IC50 2.72 nM).
- Provided as hydrochloride salt to improve solubility for assays.
- High reported purity suitable for research applications.
- Available in small pack sizes for screening and assay development.
- Molecular weight 334.85 g/mol.
Medchemexpress LLC Tirofiban (hydrochloride monohydrate) | 150915-40-5 | MFCD07368623 | 99.9% | 495.07 | 25 MG
Tirofiban hydrochloride monohydrate is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. It induces proliferation and migration on endothelial cells by inducing the production of VEGF. It can significantly reduce myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area. This product is for research use only.
- Increases proliferation of HAEC cells.
- Closes the scratch of HUVECs migration.
- Induces production of VEGF, stimulating proliferation of endothelial cells.
- Increases contraction force and improves heart function in rats after acute myocardial infarction.
- Enhances eNOS activity and reduces no-reflow area after reperfusion.
- Shows anticoagulant effect in a crush injury model in rats.
Medchemexpress LLC Verubulin hydrochloride | 917369-31-4 | 98.7% | 100 MG
Verubulin hydrochloride is the hydrochloride salt of verubulin (MPC-6827), a blood-brain barrier permeable microtubule-disrupting agent with demonstrated in vitro and in vivo anticancer activity. It is supplied for research use in solid and solution formats.
- Blood-brain barrier permeable microtubule disruptor.
- Demonstrated cytotoxic activity in MX-1 breast and other xenograft models.
- Available as solid and as solution in DMSO; pack sizes typically range from 5 mg to 500 mg.
- High purity (approx. 98.7%).
- Molecular formula C17H18ClN3O; molecular weight 315.8 g/mol.
- For research use only; not for human or veterinary use.
eMolecules H-Arg-4MbNA hydrochloride salt | 60285-94-1 | MFCD00058039 | 100mg
Chem-Impex | H-Arg-4MbNA hydrochloride salt | 100mg | 490843132 | 32695 | | 60285-94-1 | MFCD00058039 | 365.860 | C17H24ClN5O2
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Medchemexpress LLC Terbinafine | 91161-71-6 | 99.96% | 291.43 | 200 MG
Terbinafine (TDT 067) is an orally active and potent antifungal agent. It acts as a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. It also demonstrates antibacterial activity against certain Gram-positive and Gram-negative bacteria. This product is a click chemistry reagent, containing an Alkyne group that can engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Has a primary fungicidal action in vitro against most fungal pathogens, including dermatophytes, dimorphic fungi, and filamentous fungi.
- Specifically inhibits fungal ergosterol biosynthesis at the point of squalene epoxidation.
- Active following topical application and highly effective in experimental dermatophytoses when administered orally.
- In fungi-infected guinea-pigs, a significant decrease in skin temperature is observed after the fourth treatment.
Selleck Chemical LLC Duloxetine S5071-1g
Duloxetine (LY-248686) is a potent inhibitor of serotonin (5-hydroxytryptamine 5-HT) and noradrenaline (NE) uptake in vitro and in vivo and is 3- to 5-times more effective at inhibiting 5-HT uptake
eMolecules 5-AMINOPYRROLIDIN-2-ONE TFA | | | 1g
AstaTech | 5-AMINOPYRROLIDIN-2-ONE TFA | 1g | 624127358 | D72820 | 98.000 | | | 214.144 | C6H9F3N2O3
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