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Filtered Search Results
Medchemexpress LLC Procaine hydrochloride | 51-05-8 | 99.75% | 50 MG
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Procaine hydrochloride (Standard) is the analytical standard of Procaine (hydrochloride), intended for research and analytical applications. It acts as a DNA-demethylating agent with a slow onset and a short duration of action. This analytical standard is a reference standard supplied assay.
- Used in qualitative research experiments
- Used in quantitative research experiments
- Used in methodological research experiments
- Suitable for HPLC applications
- Suitable for GC applications
- Suitable for MS applications
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Medchemexpress LLC Procaine hydrochloride | 51-05-8 | MFCD00013000 | 97.9% | 1 G
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Procaine hydrochloride is a DNA-demethylating agent that acts through multiple targets. It can reduce 5-methylcytosine DNA content by 40% and demethylate densely hypermethylated CpG islands. This agent also shows growth-inhibitory effects in cancer cells, inducing mitotic arrest, and inhibits 5-HT3 receptor-mediated inward current. It is intended for research use only.
- DNA-demethylating agent
- Acts through multiple targets
- Slow onset and short duration of action
- Reduces 5-methylcytosine DNA content by 40%
- Demethylates densely hypermethylated CpG islands
- Exhibits growth-inhibitory effects in cancer cells
- Causes mitotic arrest
- Inhibits 5-HT3 receptor-mediated inward current
- Functions as an excitant of limbic system cells
- Alters synaptic transmission in amygdala output pathways
- For research use only
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Medchemexpress LLC RS-102221 hydrochloride | 187397-18-8 | 98.0% | 649.08 g/mol | C27H32ClF3N4O7S | 50 MG
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RS-102221 hydrochloride is a selective 5-HT2C receptor antagonist used in preclinical research to probe serotonin 5-HT2C-mediated signaling. It exhibits high affinity (Ki ≈ 10 nM) and strong selectivity versus related receptor subtypes and is supplied as a white to off-white solid for laboratory use.
- Selective 5-HT2C receptor antagonist with high affinity.
- Approximately 100-fold selectivity over 5-HT2A and 5-HT2B receptors.
- Supplied as a white to off-white solid suitable for research.
- Available in multiple small-scale sizes for laboratory experiments.
- Stable when stored under recommended conditions for powder and solutions.
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Medchemexpress LLC Ecopipam hydrochloride | 190133-94-9 | 99.5% | 350.28 | 50 MG
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Ecopipam hydrochloride (SCH 39166) is a potent, selective, and orally active antagonist of dopamine D1/D5 receptors, with Ki values of 1.2 nM and 2.0 nM, respectively. It demonstrates over 40-fold selectivity for D1/D5 receptors compared to D2, D4, 5-HT, and α2a receptors. This compound is suitable for research into conditions such as schizophrenia and obesity.
- Potent and selective dopamine D1/D5 receptor antagonist
- Exhibits high selectivity over D2, D4, 5-HT, and α2a receptors
- Orally active compound
- Utilized in schizophrenia and obesity research
- Abolishes nicotine-induced enhancement of sensory reinforcers in adult rats
- Antagonizes apomorphine-induced stereotypy in rats
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Medchemexpress LLC Terbinafine | 91161-71-6 | 99.96% | 291.43 | 200 MG
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Terbinafine (TDT 067) is an orally active and potent antifungal agent. It acts as a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. It also demonstrates antibacterial activity against certain Gram-positive and Gram-negative bacteria. This product is a click chemistry reagent, containing an Alkyne group that can engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Has a primary fungicidal action in vitro against most fungal pathogens, including dermatophytes, dimorphic fungi, and filamentous fungi.
- Specifically inhibits fungal ergosterol biosynthesis at the point of squalene epoxidation.
- Active following topical application and highly effective in experimental dermatophytoses when administered orally.
- In fungi-infected guinea-pigs, a significant decrease in skin temperature is observed after the fourth treatment.
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Cayman Chemical Terbinafine hydrochloride
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A broad-spectrum antifungal agent; has activity against T. rubrum, T. metagrophytes, T. verrucosum, E. floccosum, M. canis, A. fumigatus, and S. schenckii (MIC50s = 0.003-0.8 μg/ml); selectively inhibits C. albicans squalene epoxidase over rat liver epoxidase (IC50s = 0.03 and 77 μM, respectively); induces cell cycle arrest at the G0/G1 phase in COLO 205 tumor cells and HUVECs from 90-120 μM
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Medchemexpress LLC 4-(2-aminoethyl)-7-(methylamino)chromen-2-one dihydrochloride | 1883548-88-6 | MFCD30182251 | 99.5% | 291.17 g/mol | C12H16Cl2N2O2 | 5 MG
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FFN 206 dihydrochloride is a fluorescent vesicular monoamine transporter 2 (VMAT2) substrate used as a research probe to visualize and study monoamine uptake into synaptic vesicles. The compound is supplied as a stable dihydrochloride salt in small pack sizes for laboratory use.
- Fluorescent VMAT2 substrate for visualization of vesicular uptake.
- High purity suitable for analytical and preparative experiments.
- Stable dihydrochloride salt with defined molecular weight and formula.
- Recommended storage at -20°C; in solvent stability varies with temperature.
- Available in small pack sizes for research use.
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eMolecules 3-Pyridylacetic acid, HCl | 6419-36-9 | 5G | Purity: 98%
Combi-Blocks | 3-Pyridylacetic acid, HCl | 5G | 6419-36-9 | MFCD00012819
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Medchemexpress LLC L-368,899 hydrochloride | 160312-62-9 | 99.9% | 591.23 | 25 MG
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L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist. It is used as a tocolytic agent and shows less activity on VP receptors in human and rat liver and kidney.
- Potent, orally bioavailable, non-peptide oxytocin receptor antagonist
- IC50s of 8.9 nM for rat uterus oxytocin receptor
- IC50s of 26 nM for human uterus oxytocin receptor
- Used as a tocolytic agent
- Less active on VP receptor in human and rat liver and kidney
- Exhibits similar pharmacokinetics in rats and dogs
- Orally available with demonstrated bioavailability in rats
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Apexbio Technology LLC Tirofiban hydrochloride monohydrate 150915-40-5 10mM (in 1mL DMSO)
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Tirofiban hydrochloride monohydrate (CAS 150915-40-5) is a small-molecule inhibitor targeting platelet glycoprotein IIb/IIIa receptors It is designed to reversibly antagonize the binding of fibrinogen to these receptors thereby inhibiting platelet aggregation and thrombus formation Tirofiban hydrochloride monohydrate exerts its biological activity primarily through selective reversible inhibition of glycoprotein IIb/IIIa-mediated platelet aggregation Based on these pharmacological properties tirofiban hydrochloride monohydrate holds research potential in antithrombotic therapy and the investigation of unstable angina and thrombus-associated cardiovascular conditions
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Abcam VU 0238429, allosteric M5 modulator, 5MG
MW 351.28 Da, Purity >99%. Selective, positive allosteric M5 modulator (EC50 values are 1.16 and >30 μM at M5 and M1/ M3 receptors, respectively). Shows no activity at M2 and M4 receptors.
The product is subject to the following: Abcam Restricted Use Statement
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Medchemexpress LLC Cp-409092 hydrochloride | 225240-86-8 | 99.8% | 333.81 g/mol | C17H20ClN3O2 | 25 MG
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CP-409092 hydrochloride is a research chemical that functions as a partial agonist of the GABAA receptor and has reported anxiolytic activity. Supplied as the hydrochloride salt, it is provided as a high-purity solid for in vitro and in vivo pharmacology studies.
- Acts as a partial agonist of the GABAA receptor.
- Demonstrates reported anti-anxiety (anxiolytic) activity in pharmacological assays.
- High purity (≈99.8%) with white to off-white solid appearance.
- Soluble in water and DMSO with ultrasonic assistance for stock preparation.
- Documented with COA, SDS, and data sheet for research handling.
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Medchemexpress LLC Cyclopentanecarboxylic acid, 1-(4-nitrophenyl)-, 2-(diethylamino)ethyl ester, hydrochloride | 98636-73-8 | MFCD00673872 | 99.6% | 370.87 g/mol | C18H27ClN2O4 | 25 MG
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Nitrocaramiphen hydrochloride is a selective M1 muscarinic receptor antagonist supplied as the hydrochloride salt for research use. It inhibits muscarine-induced hyperpolarization in muscle fibers and is provided as a white to off-white solid suitable for biochemical and pharmacological studies.
- Selective M1 receptor antagonist (Ki: 5.5 nM).
- High purity: 99.6% (manufacturer COA).
- White to off-white solid, molecular formula C18H27ClN2O4.
- Molecular weight 370.87 g/mol.
- Available in small milligram quantities for research use.
- Store sealed away from moisture; in solvent: -80°C (6 months), -20°C (1 month).
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Medchemexpress LLC Co 101244 hydrochloride | 193356-17-1 | 99.9% | 377.90 | C21H28ClNO3 | 10 MG
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Co 101244 hydrochloride (PD 174494 hydrochloride) is a selective antagonist of NR2B (GluN2B)-containing NMDA receptors used to study NMDA receptor pharmacology and neuronal signaling in vitro. The hydrochloride salt is characterized by formula C21H28ClNO3, molecular weight 377.90 g/mol, and supplier-reported purity near 99.9%. It is supplied in small-molecule formats for research assays.
- Selective antagonist of NR2B-containing NMDA receptors.
- High chemical purity for reproducible experimental results.
- Hydrochloride salt form for improved solubility in assay solvents.
- Suitable for in vitro pharmacology and receptor binding assays.
- Available in mg-scale solid and DMSO solution formats.
- Molecular weight and formula provided for dosing calculations.
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Medchemexpress LLC BPR1J-097 hydrochloride | 00-00-0 | 99.2% | C27H29ClN6O3S | 10MG
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BPR1J-097 hydrochloride is a small-molecule FLT3 kinase inhibitor with nanomolar potency for use in biochemical and cellular research. Supplied as the hydrochloride salt with high chemical purity, it is intended for pharmacological profiling and in vitro assay applications where selective FLT3 inhibition is required.
- Potent FLT3 inhibition (IC50 ~11 nM).
- High chemical purity (99.2%).
- Hydrochloride salt form for improved solubility.
- Characterized by molecular formula C27H29ClN6O3S and MW 553.08.
- Intended for research use in biochemical and cellular assays.
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