Hydrochlorides
eMolecules 1824276-00-7 | 3-(TRIFLUOROMETHYL)QUINOLIN-7-AMINE | AstaTech | MFCD28133472 | 212.175 | C10H7F3N2 | 95.000 | Nc1ccc2cc(cnc2c1)C(F)(F)F | 1g | 410711973
3-(TRIFLUOROMETHYL)QUINOLIN-7-AMINE | AstaTech | 1824276-00-7 | MFCD28133472 | 212.175 | C10H7F3N2 | 95.000 | Nc1ccc2cc(cnc2c1)C(F)(F)F | 1g | 410711973
Medchemexpress LLC CP 93129 dihydrochloride | 879089-64-2 | 99.0% | 288.17 g·mol⁻1 | C12H15Cl2N3O | 1 MG
CP 93129 dihydrochloride is a selective 5-HT1B receptor agonist supplied for research use. It is used in pharmacology and neuroscience studies, including investigations related to Parkinson's disease, and is provided as a high-purity solid suitable for analytical, in vitro, and in vivo applications.
- Selective 5-HT1B receptor agonist suitable for receptor pharmacology studies.
- High purity (99.0%) for consistent experimental results.
- Molecular weight 288.17 g·mol⁻1 and formula C12H15Cl2N3O for precise calculations.
- Off-white to light yellow solid for convenient handling and storage.
- Recommended storage at 4°C, sealed and protected from moisture and light.
- Available in small, accurately weighed milligram quantities for dosing and assays.
Apexbio Technology LLC Tirofiban hydrochloride monohydrate 150915-40-5 5mg
Tirofiban hydrochloride monohydrate (CAS 150915-40-5) is a small-molecule inhibitor targeting platelet glycoprotein IIb/IIIa receptors It is designed to reversibly antagonize the binding of fibrinogen to these receptors thereby inhibiting platelet aggregation and thrombus formation Tirofiban hydrochloride monohydrate exerts its biological activity primarily through selective reversible inhibition of glycoprotein IIb/IIIa-mediated platelet aggregation Based on these pharmacological properties tirofiban hydrochloride monohydrate holds research potential in antithrombotic therapy and the investigation of unstable angina and thrombus-associated cardiovascular conditions
eMolecules 53179-07-0 | Medchem Express | Nisoxetine | 5mg | 783660599 | HY-B1704 | MFCD00865443 | 271.36 | C17H21NO2
Medchem Express | Nisoxetine | 5mg | 783660599 | HY-B1704 | 53179-07-0 | MFCD00865443 | 271.360 | C17H21NO2
Medchemexpress LLC JMV 2959 hydrochloride | 2448414-54-6 | 545.08 | 25 MG
JMV 2959 hydrochloride is a growth hormone secretagogue receptor type 1a (GHS-R1a) antagonist. It exhibits an IC50 of 32±3 nM in LLC-PK1 cells for GHS-R1a and does not induce intracellular calcium mobilization by itself.
- GHS-R1a antagonist with an IC50 of 32±3 nM in LLC-PK1 cells.
- Dissociation constant (Kb) for the receptor complex is 19±6 nM.
- Decreases acoustic startle responses (ASR) and increases prepulse inhibition (PPI) in vivo.
- Blocks Phencyclidine (PCP)-induced deficits in PPI.
Medchemexpress LLC Drp1i27 (dihydrochloride) | C20H28Cl2N6O | 25 MG
DRP1i27 dihydrochloride is a potent inhibitor of human Drp1 (dynamin-related protein 1). It binds to the GTPase site of Drp1 through hydrogen bonds to Gln34 and Asp218. This product targets Drp1-mediated mitochondrial fission in cell line models and offers protection against simulated ischemia-reperfusion injury.
- Potent inhibitor of human Drp1 (dynamin-related protein 1)
- Binds to the GTPase site of Drp1
- Targets Drp1-mediated mitochondrial fission in cell line models
- Protects against simulated ischemia-reperfusion injury
- Increases cellular networks of mitochondria in human and mouse fibroblasts in a Drp1-dependent manner
Medchemexpress LLC Bay-6672 hydrochloride | 2247520-31-4 | 98.0% | 581.33 | C26H28BrCl2N3O3 | 5 MG
BAY-6672 hydrochloride is a research-grade small molecule antagonist of the human Prostaglandin F (FP) receptor with a reported IC50 of 11 nM. Supplied as the hydrochloride salt and characterized at high purity, it is intended for in vitro pharmacology and biochemical studies and is available as a solid or as a 10 mM solution in DMSO. For research use only; not for human or clinical use.
- Potent FP receptor antagonist (IC50 = 11 nM).
- High purity suitable for pharmacological assays.
- Available as solid mg quantities and as a 10 mM DMSO solution.
- Characterized molecular weight and formula for identification.
- Intended for in vitro research use only.
Medchemexpress LLC MRTX9768 hydrochloride | 2629314-68-5 | 99.9% | 460.89 | 100 MG
MRTX9768 hydrochloride is a potent, selective, orally active, first-in-class PRMT5-MTA complex inhibitor. It inhibits SDMA and cell proliferation in HCT116 MTAP-del cells, showing marked selectivity over HCT116 MTAP-WT cells. This compound leads to sustained SDMA inhibition and demonstrates dose-dependent inhibition in MTAP-del tumors in vivo. It selectively targets MTAP/CDKN2A-deleted tumors, such as glioblastoma, and exhibits a favorable ADME profile.
- Potent and selective PRMT5-MTA complex inhibitor
- Orally active
- Targets MTAP/CDKN2A-deleted tumors
- Exhibits favorable ADME profile
- Leads to sustained SDMA inhibition
- Inhibits cell proliferation in HCT116 MTAP-del cells
Medchemexpress LLC T-3775440 hydrochloride | 1422535-52-1 | 99.1% | 346.85 g/mol | C18H23ClN4O | 10 MG
T-3775440 hydrochloride is the hydrochloride salt of T-3775440, an irreversible lysine-specific demethylase 1 (LSD1) inhibitor used in biochemical and cellular research. It has a reported IC50 of 2.1 nM and is supplied as a solid salt for assay and mechanistic studies.
- Irreversible LSD1 inhibitor with reported IC50 = 2.1 nM.
- Hydrochloride salt form suitable for biochemical and cell-based assays.
- High purity suitable for research use (reported purity 99.13%).
- Molecular formula C18H23ClN4O; molecular weight 346.85 g/mol.
- Packaged in small research quantities for assay development and validation.
eMolecules 5407-57-8 | 1,2-ETHANEDIAMINE,N1-(7-CHLORO-4-QUINOLINYL) | AstaTech | MFCD02179802 | 221.690 | C11H12ClN3 | 95.000 | NCCNc1ccnc2cc(Cl)ccc12 | 1g | 282982525
1,2-ETHANEDIAMINE,N1-(7-CHLORO-4-QUINOLINYL) | AstaTech | 5407-57-8 | MFCD02179802 | 221.690 | C11H12ClN3 | 95.000 | NCCNc1ccnc2cc(Cl)ccc12 | 1g | 282982525
Medchemexpress LLC VU-1545 | 890764-63-3 | 99.0% | 402.38 | 100 MG
VU-1545 is a metabotropic glutamate receptor 5 positive allosteric modulator (mGluR5 PAM) with a Ki of 156 nM and an EC50 of 9.6 nM.
- Promotes AKT activation at concentrations of 0.1 and 1.0 μM.
- Neuroprotective in a mouse model of Huntington's disease.
- For research use only, not for sale to patients.
Medchemexpress LLC Co 101244 hydrochloride (PD 174494) | 193356-17-1 | 99.9% | 377.90 | C21H28ClNO3 | 50 MG
Co 101244 hydrochloride is the hydrochloride salt of a small-molecule NR2B-containing NMDA receptor antagonist supplied for research use. It is a light yellow to yellow solid with high purity and characterized molecular properties and storage/solubility data for in vitro and in vivo applications.
- Selective NR2B NMDA receptor antagonist useful for neuroscience research.
- High purity suitable for analytical and biological assays.
- Well-characterized solubility in DMSO for solution preparation.
- Stable when stored sealed at recommended temperatures.
- Available in multiple small-scale quantities for laboratory use.
Medchemexpress LLC Ipn60090 dihydrochloride | 2102101-72-2 | 99.7% | 605.44 g/mol | C24H29Cl2F3N8O3 | 1 ML
IPN60090 dihydrochloride is a potent, selective small-molecule inhibitor of glutaminase 1 (GLS1), provided as a dihydrochloride salt for preclinical research. It is offered as a ready-to-use 10 mM solution in DMSO (1 mL) or as solid samples, with reported high purity and documented in vitro and in vivo activity supporting use in solid tumor studies.
- Highly selective GLS1 inhibitor with reported IC50 = 31 nM.
- Inhibits A549 cell proliferation (IC50 = 26 nM).
- Available as 10 mM solution in DMSO (1 mL) or multiple solid sizes for experimental flexibility.
- High purity suitable for biochemical and cell-based assays.
- Documented pharmacokinetic and efficacy data in preclinical models.
Apexbio Technology LLC VU 0364439 1246086-78-1 100mg
VU 0364439 (CAS 1246086-78-1) is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4) a member of the class C G protein-coupled receptor (GPCR) family involved in regulating glutamatergic neurotransmission In vitro studies have demonstrated that VU 0364439 enhances mGluR4 activity with an EC50 of 19 8 nM exhibiting greater maximal response and potency compared to the partially selective PAM ()-PHCCC Although its pharmacokinetic properties limit in vivo applications VU 0364439 serves as a valuable tool compound for investigating mGluR4 function and modulation in cellular assays
Medchemexpress LLC Naloxone hydrochloride | 357-08-4 | MFCD00069322 | 99.7% | 363.84 g/mol | C19H22ClNO4 | 10 MG
Naloxone hydrochloride is a research-grade reference standard of naloxone, a competitive opioid receptor antagonist used to reverse opioid effects and to support pharmacology and analytical method development. Supplied as a 10 mg reference material with accompanying certificate of analysis and safety data sheet, it is intended for research and analytical applications.
- High purity suitable for analytical and reference applications (99.7%).
- Provided with certificate of analysis and safety data sheet.
- Suitable for opioid receptor pharmacology and receptor-binding studies.
- Molecular weight 363.84 g/mol; formula C19H22ClNO4.
- Packaged as a 10 mg reference standard for method development and validation.