Hydrochlorides
Medchemexpress LLC Naloxone hydrochloride | 357-08-4 | 100.0% | 363.84 | 100 MG
Naloxone hydrochloride is an antagonist of the Opioid receptor. It alleviates respiratory depression induced by opioid overdose, though it may also cause pulmonary edema and cardiac arrhythmias. It is intended for research use only and not for sale to patients.
- Opioid receptor antagonist
- Alleviates opioid-overdose-induced respiratory depression
- Data sheet, COA, SDS, and handling instructions provided
- Soluble in H2O (62.5 mg/mL) and DMSO (≥ 30 mg/mL)
Medchemexpress LLC L-368,899 hydrochloride | 160312-62-9 | 100.0% | 591.23 | 5 MG
L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist. It functions as a tocolytic agent, showing high affinity for oxytocin receptors in both rat and human uterus.
- Potent and selective oxytocin receptor antagonist
- Orally bioavailable compound
- Exhibits IC50s of 8.9 nM for rat uterus oxytocin receptor and 26 nM for human uterus oxytocin receptor
- Shows less activity on VP receptor in human and rat liver and kidney
Medchemexpress LLC DRP1i27 dihydrochloride | 1453028-33-5 | C20H28Cl2N6O | 1 MG
DRP1i27 dihydrochloride is a potent inhibitor of human Drp1 (dynamin-related protein 1). It binds to the GTPase site of Drp1, forming hydrogen bonds with Gln34 and Asp218. This compound targets Drp1-mediated mitochondrial fission in cell line models and offers protection against simulated ischemia-reperfusion injury.
- Potent inhibitor of human Drp1
- Binds to the GTPase site of Drp1
- Targets mitochondrial fission in cell line models
- Offers protection against simulated ischemia-reperfusion injury
Medchemexpress LLC Lobeline (hydrochloride) | 134-63-4 | 100.0% | 500 MG
Lobeline (α-Lobeline) hydrochloride is a brain-penetrant nicotinic receptor agonist. It increases dopamine (DA) release by inhibiting DA uptake into synaptic vesicles and altering presynaptic DA storage, making it effective in smoking cessation.
- Brain-penetrant nicotinic receptor agonist
- Increases dopamine (DA) release
- Inhibits DA uptake into synaptic vesicles
- Alters presynaptic DA storage
- Effective in smoking cessation
- Soluble in water at 6 mg/mL
- White to off-white solid appearance
- Molecular weight of 373.92
- Chemical formula C22H28ClNO2
- Melting/freezing point 183-185 °C
Medchemexpress LLC Procaine hydrochloride (Standard) | 51-05-8 | MFCD00013000 | 99.8% | 100 MG
Procaine hydrochloride (Standard) is an analytical standard and reference assay for research and analytical applications. It acts as a DNA-demethylating agent with a slow onset and short duration. This compound is suitable for qualitative, quantitative, and methodological research experiments.
- Intended for research and analytical applications.
- Acts as a DNA-demethylating agent.
- Has a slow onset and short duration of action.
- Suitable for qualitative research experiments.
- Suitable for quantitative research experiments.
- Suitable for methodological research experiments.
- Used in HPLC.
- Used in GC.
- Used in MS.
Medchemexpress LLC DAPI dihydrochloride | 28718-90-3 | 99.9% | 1 MG
DAPI dihydrochloride | 28718-90-3 | 99.9% | 1 MG
Medchemexpress LLC Azaphen dihydrochloride monohydrate | 63302-99-8 | 99.9% | C16H23Cl2N5O2 | 500 MG
Azaphen dihydrochloride monohydrate, also known as Pipofezine or Azafen, is a potent inhibitor of serotonin reuptake. It functions as a tricyclic antidepressant (TCA) and is approved in Russia for the treatment of depression.
- Potent inhibitor of serotonin reuptake
- Acts as a tricyclic antidepressant
- Used for the treatment of depression
Selleck Chemical LLC Tirofiban S3085-5mg
Tirofiban (MK-383) is a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM
Selleck Chemical LLC VU-29 S1970-25mg
VU-29 is a positive allosteric modulator of metabotropic glutamate 5 (mGlu5) receptor with EC50 of 9 nM and Ki 244 nM for rat mGluR5 which is selective for mGluR5 relative to other mGluR subtypes
Medchemexpress LLC DRP1i27 dihydrochloride | C20H28Cl2N6O | 1 ML
DRP1i27 dihydrochloride is a potent inhibitor of human Drp1 (dynamin-related protein 1). It binds to the GTPase site of Drp1, forming hydrogen bonds with Gln34 and Asp218. This compound targets Drp1-mediated mitochondrial fission in cell line models and offers protection against simulated ischemia-reperfusion injury.
- Directly binds to and inhibits the GTPase activity of human Drp1.
- Increases cellular networks of mitochondria in human and mouse fibroblasts in a Drp1-dependent manner.
- Has a binding affinity of 286 μM in the SPR assay and a KD value of 190 μM via the MST assay.
Sigma Aldrich Fine Chemicals Biosciences O-Phenylenediamine Dihydrochloride | 99% Purity | CAS No.: 615-28-1 | MDL No.: MFCD00012966 | 150mg tablet
o-Phenylenediamine dihydrochloride | Purity: 99% | M. W.: 181.58 | CAS No.: 615-28-1 | MDL No.: MFCD00012966 | 150mg tablet
Medchemexpress LLC SB 202190 hydrochloride | 350228-36-3 | MFCD28391789 | 99.7% | 367.80 g·mol⁻¹ | C20H15ClF3NO | 1 ML
SB 202190 hydrochloride is a selective p38 MAP kinase inhibitor used in cell signaling and pharmacology research. It is commonly supplied in concentrated stock formats for convenient preparation of working solutions.
- Selective p38 MAPK inhibitor; p38α IC50 ≈ 50 nM, p38β2 IC50 ≈ 100 nM.
- Supplied in a 10 mM solution format (1 mL) for ready stock preparation.
- Molecular weight 367.80 g·mol⁻¹; formula C20H15ClF3NO.
- DMSO-soluble; may require sonication and warming (up to 60°C) for full dissolution.
- Storage in solvent: -80°C (up to 6 months) or -20°C (up to 1 month); keep sealed and dry.
- High purity (manufacturer reported ~99.7%) suitable for research applications.
Medchemexpress LLC preQ1 dihydrochlorid 10mg | 86694-45-3 | 252.10 | C7H11Cl2N5O | 10 MG
preQ1 dihydrochloride is a guanine-derived nucleobase used as a precursor in the biosynthesis of queuine and as a ligand for PreQ1 riboswitch studies. Supplied as the dihydrochloride salt for research use, the compound has defined solubility and storage recommendations.
- Precursor in queuine biosynthesis and useful for tRNA modification studies.
- Binds the PreQ1 riboswitch aptamer with high affinity.
- Solubility: DMSO 125 mg/mL; water 15 mg/mL (may require ultrasonic agitation).
- Solid storage recommended at 4°C in a sealed container, protected from moisture and light.
- In-solution stability: store at -80°C for up to 6 months or -20°C for up to 1 month when sealed.
Medchemexpress LLC SB 202190 hydrochloride | 350228-36-3 | MFCD17215958 | 99.7% | 367.80 g·mol⁻1 | C20H15ClFN3O | 50 MG
SB 202190 hydrochloride is the hydrochloride salt of a selective p38 mitogen-activated protein kinase (MAPK) inhibitor used in biochemical and cellular research to probe p38 signaling pathways. It is supplied as a solid and as a ready-to-use DMSO solution, and is characterized by high purity and defined storage recommendations.
- Selective inhibitor of p38 MAPK isoforms.
- High purity suitable for research applications.
- Available as solid and as a 10 mM solution in DMSO.
- Light yellow solid appearance for easy visual inspection.
- Requires low-temperature, sealed storage to preserve stability.