Unclassified Organic Compounds
Sigma Aldrich Fine Chemicals Biosciences Safranal >=90%, stabilized | 116-26-7 | MFCD00209531 | 25G
Safranal >=90%, stabilized | Purity: >=90% | Mol Wt: 150.22 | 116-26-7 | MFCD00209531 | 25G
eMolecules Ambeed / 266-Trimethylcyclohexa-13-dienecarbaldehyde / 1g / 572143890 / A829107 / / 116-26-7 / MFCD00209531 / 150.221 / C10H14O
Ambeed / 266-Trimethylcyclohexa-13-dienecarbaldehyde / 1g / 572143890 / A829107 / / 116-26-7 / MFCD00209531 / 150.221 / C10H14O
3-Ethyl-2-methylpentane 99.0+%, TCI America™
CAS: 609-26-7 Molecular Formula: C8H18 Molecular Weight (g/mol): 114.23 MDL Number: MFCD00048665 InChI Key: DUPUVYJQZSLSJB-UHFFFAOYSA-N PubChem CID: 11863 IUPAC Name: 3-ethyl-2-methylpentane SMILES: CCC(CC)C(C)C
Palladium(II) Acetate Trimer 98.0+%, TCI America™
CAS: 53189-26-7 Molecular Formula: C12H24O12Pd3 Molecular Weight (g/mol): 679.572 InChI Key: FUKTVTHLBVPABW-UHFFFAOYSA-N Synonym: Hexakis(acetato)tripalladium(II), Tripalladium(II) Hexaacetate PubChem CID: 85470766 IUPAC Name: acetic acid;palladium SMILES: CC(=O)O.CC(=O)O.CC(=O)O.CC(=O)O.CC(=O)O.CC(=O)O.[Pd].[Pd].[Pd]
Medchemexpress LLC 116-9e 100mg | 831217-43-7 | 100 MG
116-9e (MAL2-11B) is a small-molecule inhibitor of the Hsp70 co-chaperone DNAJA1. It inhibits Simian Virus 40 (SV40) replication and DNA synthesis and suppresses tumor antigen (TAg) ATPase activity, making it suitable for research into chaperone-mediated viral replication and protein interactions.
- Molecular weight: 512.60 g/mol.
- Chemical formula: C31H32N2O5.
- CAS registry number: 831217-43-7.
- Purity: 98.28% (reported).
- Appearance: solid, white to yellow.
- Recommended form: 10 mM solution in DMSO (1 mL) or solid for reconstitution.
- Storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); in solvent at -80°C (6 months) or -20°C (1 month).
- Pack size: 100 MG.
Medchemexpress LLC 116-9e 25mg | 831217-43-7 | 25 MG
116-9e (MAL2-11B) is a small-molecule inhibitor of the Hsp70 co-chaperone DNAJA1 that inhibits Simian Virus 40 (SV40) replication and DNA synthesis. It is provided as a research-grade biochemical for in vitro and in vivo studies; recommended solvents and in vivo formulation protocols are available.
Medchemexpress LLC 116-9e 50mg | 831217-43-7 | 512.60 | C31H32N2O5 | 50 MG
116-9e (MAL2-11B) is a small-molecule inhibitor of the Hsp70 co-chaperone DNAJA1 and an inhibitor of Simian Virus 40 (SV40) replication and DNA synthesis. Supplied as a high-purity research reagent, it is intended for in vitro biochemical and cellular studies.
- High purity (98.28%) suitable for biochemical assays.
- Molecular formula C31H32N2O5 and molecular weight 512.60 g·mol-1.
- Soluble in DMSO; available as a 10 mM solution in DMSO for convenience.
- Offered in multiple solid pack sizes to fit different experimental scales.
Medchemexpress LLC Isopimaric acid | 5835-26-7 | 5 MG
Isopimaric acid is a potent opener of large conductance calcium-activated K+ (BK) channels, derived from plants, particularly Pinaceae Pinus nigra Arn. This product is a white to off-white solid with a molecular weight of 302.45 and a chemical formula of C20H30O2. It is classified as an "Other Terpenoid" with a purity of 99.88% and is intended for research use only.
- Potent opener of large conductance calcium activated K+ (BK) channels
- Intended for research use only
- Appears as a white to off-white solid
- Molecular weight: 302.45
- Chemical formula: C20H30O2
- Classified as a terpenoid
- Initial source: Plants (Pinaceae Pinus nigra Arn)
- Purity: 99.88%
- Solubility: ≥ 25 mg/mL (82.66 mM) in DMSO
- Storage: Powder at -20°C for 3 years; In solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Lartesertib | 2495096-26-7 | C23H21FN6O3 | 100 MG
Lartesertib is a highly potent inhibitor of the serine/threonine protein kinase ATM. It can inhibit the growth of multiple hematopoietic cell lines and, when combined with ATR inhibitors, promotes tumor cell death and activates the immune signaling pathway. This compound also demonstrates anti-tumor activity and alters the tumor microenvironment in the MC-38 mouse tumor model, leading to changes in PD-L1 expression and immune cell populations.
- Highly potent inhibitor of the serine/threonine protein kinase ATM.
- Inhibits the growth of various hematopoietic cell lines.
- Promotes tumor cell death in combination with ATR inhibitors.
- Activates the immune signaling pathway.
- Demonstrates anti-tumor activity.
- Alters the tumor microenvironment.
- Upregulates PD-L1 on immune and tumor cells.
- Modulates tumor immune cell populations.
Medchemexpress LLC 116-9e 10mg | 831217-43-7 | 512.60 Da | C31H32N2O5 | 10 MG
116-9e (MAL2-11B) is a small-molecule inhibitor of the Hsp70 co-chaperone DNAJA1 that suppresses Simian Virus 40 (SV40) replication and DNA synthesis. It also inhibits tumor antigen (TAg) endogenous ATPase activity and TAg-mediated activation of Hsp70. Supplied as a white to yellow solid, the compound is intended for biochemical research and includes analytical documentation for quality verification.
- Inhibits DNAJA1 and reduces SV40 replication and DNA synthesis.
- Inhibits TAg endogenous ATPase activity.
- White to yellow solid suitable for biochemical assays.
- High purity (98.28%) as provided by supplier.
- Soluble in DMSO at 100 mg/mL for stock preparations.
- Powder storage: -20°C for long-term stability; in solution store at -80°C for extended storage.
- Analytical documentation available: COA, H NMR, LCMS, and SDS.
Medchemexpress LLC ANI-7 100mg | 931417-26-4 | 100 MG
ANI-7 ((Z)-2-(3,4-dichlorophenyl)-3-(1H-pyrrol-2-yl)acrylonitrile) is a small-molecule activator of the aryl hydrocarbon receptor (AhR) supplied as a solid for research use. It is intended for use in cell-based and biochemical assays to study AhR signaling, CYP1 enzyme induction, and related cancer biology mechanisms.
- Activator of aryl hydrocarbon receptor for research applications.
- High purity (~99.01%) suitable for biochemical and cellular assays.
- CAS number 931417-26-4 for unambiguous identification.
- Solid, light yellow to yellow appearance; soluble in DMSO for assay preparation.
- Molecular weight 263.12 g/mol, useful for dosing and calculations.
- Available in milligram-scale quantities for screening and preclinical studies.
Sigma Aldrich Fine Chemicals Biosciences CYM-5541 >=98% (HPLC) | 945128-26-7 | 5MG
CYM-5541 >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 316.44 | 945128-26-7 | 5MG
Medchemexpress LLC STAT3-IN-3 | 2361304-26-7 | 98.4% | 100 MG
STAT3-IN-3 is a potent and selective inhibitor of signal transducer and activator of transcription 3 (STAT3). It exhibits anti-proliferative activity by inducing apoptosis in breast cancer cells and is considered a promising mitochondria-targeting STAT3 inhibitor for cancer research. This compound inhibits STAT3 tyrosine and serine phosphorylation and its DNA-binding activity. In vivo studies have shown potent antitumor activity against implanted 4T1 breast tumors.
- Potent and selective STAT3 inhibitor
- Induces apoptosis in breast cancer cells
- Mitochondria-targeting for cancer research
- Inhibits STAT3 phosphorylation and DNA-binding
- Down-regulates STAT3 target genes
- Increases ROS production
- Reduces mitochondrial membrane potential
- Induces caspase cleavage
- Exhibits anti-proliferative activity
- Potent antitumor activity in vivo
Medchemexpress LLC EPI-7170 | 2139288-26-7 | 99.9% | 540.88 | 5 MG
EPI-7170 is a ralaniten analogue and a potent antagonist of the androgen receptor (AR) N-terminal structural domain. It effectively blocks the transcriptional activity of both full-length AR (FL-AR) and AR splice variants (AR-Vs). It has demonstrated antitumor effects, particularly against enzalutamide-resistant castration-resistant prostate cancer (CRPC).
- Inhibits cell proliferation.
- Enhances the effect of enzalutamide.
- Synergistically inhibits AR transcriptional activity.
- Increases G1 phase and decreases S phase, reducing protein expression levels.
- Shows anti-tumor activity in vivo.
- Significantly reduces tumor volume.
Medchemexpress LLC Mal-PEG5-acid | 1286755-26-7 | ≥97.0% | 100 MG
Mal-PEG5-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets a specific protein. These molecules function by harnessing the intracellular ubiquitin-proteasome system to selectively degrade target proteins. Its molecular weight is 389.40, with a chemical formula of C17H27NO9. It appears as a liquid, light brown to yellow in color, with a density of 1.249±0.06 g/cm3.
- For research use only
- Should be shipped at room temperature in the continental US
- Storage at -20°C, protected from light
- In solvent, can be stored at -80°C for 6 months or -20°C for 1 month, protected from light
- Soluble in DMSO at 100 mg/mL