Tetrahydrofuran
Medchemexpress LLC Pelcitoclax (APG-1252) | 1619923-36-2 | 99.7% | 1281.85 g·mol⁻¹ | C57H66ClF4N6O11PS4 | 5 MG
Pelcitoclax is a small-molecule dual inhibitor of Bcl-2 and Bcl-xL used in oncology research. It induces apoptosis and has demonstrated antitumor activity in preclinical models, and is supplied with characterized molecular properties and high analytical purity for research applications.
- Dual Bcl-2 and Bcl-xL inhibition mechanism
- Promotes apoptosis in tumor cells
- Demonstrated antitumor activity in preclinical studies
- High analytical purity for consistent results
- Available as solid and ready-to-use DMSO solution formats
Medchemexpress LLC Bifenthrin | 82657-04-3 | MFCD00143694 | 99.8% | 422.87 | C23H22ClF3O2 | 10 MG
Bifenthrin is a synthetic pyrethroid insecticide supplied as an analytical standard for research and analytical applications. It is intended for use as a reference material in qualitative and quantitative analysis, method development, and instrument calibration for chromatographic and mass spectrometric techniques.
- Analytical standard suitable for HPLC, GC, and MS.
- High purity (99.8% by LCMS).
- Molecular formula C23H22ClF3O2; molecular weight 422.87.
- Off-white to white solid physical form.
- Store under recommended conditions shown on the certificate of analysis.
Medchemexpress LLC G5-7 10mg | 939681-36-4 | 383.39 g/mol | C22H19F2NO3 | 10 MG
G5-7 is an orally active, allosteric JAK2 inhibitor intended for research use. It selectively inhibits JAK2-mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3, and has been reported to induce cell cycle arrest, apoptosis, and exhibit antiangiogenic effects relevant to glioma studies.
- Allosteric JAK2 inhibitor with selective inhibition of EGFR (Tyr1068) and STAT3 phosphorylation.
- Reported to induce cell cycle arrest and apoptosis in cellular studies.
- Exhibits antiangiogenic activity relevant to glioma research.
- Off-white to light yellow solid powder suitable for research use.
- High purity (99.55%) to support experimental reproducibility.
- Recommended storage: powder at -20°C; in solvent -80°C for 6 months or -20°C for 1 month.
Medchemexpress LLC Zectivimod | 1623066-63-6 | 99.35% | 528.47 | 50 MG
Zectivimod is a sphingosine-1-phosphate receptor agonist. It can be utilized in the research of autoimmune diseases, chronic inflammatory diseases, and immunoregulation disorders.
- Sphingosine-1-phosphate receptor agonist
- Research applications in autoimmune diseases
- Research applications in chronic inflammatory diseases
- Research applications in immunoregulation disorders
eMolecules 121138-01-0 | 3-Iodotetrahydrofuran | Ambeed | MFCD09878873 | 198.003 | C4H7IO | 98.000 | IC1CCOC1 | 100mg | 571783746
3-Iodotetrahydrofuran | Ambeed | 121138-01-0 | MFCD09878873 | 198.003 | C4H7IO | 98.000 | IC1CCOC1 | 100mg | 571783746
Medchemexpress LLC Tmx-4116 | 2766385-56-0 | 99.8% | C17H19N5O4S | 100 MG
TMX-4116 is a casein kinase 1α (CK1α) degrader. It exhibits a degradation preference for CK1α with DC50s less than 200 nM in MOLT4, Jurkat, and MM.1S cells.
- Can be utilized for research related to multiple myeloma.
- Demonstrates a high degradation preference for CK1α in MOLT4 cells at 1 μM for 4 hours.
- Induces primary target degradation of CK1α without downregulating PDE6D, IKZF1, and IKZF3 in MOLT4 cells.
Medchemexpress LLC Melanin probe-2 | 1285446-04-9 | 99.4% | 300.19 | 100 MG
Melanin probe-2 (compound 5) is a non-radioactive bromopicolinamide precursor utilized in the synthesis of 18F-Labeled Picolinamide PET probes. This product is for research use only.
- Non-radioactive bromopicolinamide precursor
- Used for the synthesis of 18F-Labeled Picolinamide PET probe
- Research use only
Medchemexpress LLC AST5902 trimesylate | 2929417-90-1 | 98.75% | 842.88 | 100 MG
AST5902 trimesylate is the principal metabolite of Alflutinib in vitro and in vivo. It exhibits antineoplastic activity, and Alflutinib is known as an EGFR inhibitor.
- Principal metabolite of Alflutinib
- Exhibits antineoplastic activity
- Targets EGFR
Medchemexpress LLC 5-amino-6-methoxy-2-(3',4',5'-trimethoxyphenylsulfonyl)quinoline | 1346169-92-3 | MFCD32174244 | 99.6% | 404.44 | C19H20N2O6S | 25 MG
A quinoline-derived research compound that acts as a microtubule-depolymerizing agent. It inhibits tubulin polymerization, induces mitotic arrest and c-Jun N-terminal kinase-mediated apoptosis, and can sensitize resistant cancer cell lines to mTOR pathway inhibitors. Supplied as a solid for laboratory research use.
- Microtubule-depolymerizing activity observed in cell assays.
- Induces mitotic arrest and JNK-mediated apoptosis.
- High purity (~99.6%) for reproducible results.
- Molecular weight 404.44; formula C19H20N2O6S.
- Soluble in DMSO at 100 mg/mL; ultrasonic agitation recommended.
- Available in small sample sizes (5 mg-100 mg); powder storage at -20°C.
Medchemexpress LLC Sar-Arg-Val-Tyr-Val-His-NH2 | 2410957-04-7 | 96.6% | 742.87 | 10 MG
Sar-Arg-Val-Tyr-Val-His-NH2 is a Gq-biased agonist that exhibits 10-fold larger molecular efficacies at the AT1R-Gq fusion protein compared with the AT1R-βarr2 fusion protein. This compound is targeted at the Angiotensin Receptor and acts via the GPCR/G Protein pathway.
- Gq-biased agonist
- Exhibits 10-fold larger molecular efficacies at AT1R-Gq fusion protein
- Targets Angiotensin Receptor
- Acts via GPCR/G Protein pathway
Medchemexpress LLC Hypidone hydrochloride | 1339058-04-6 | 99.7% | 334.84 g/mol | C18H23ClN2O2 | 25 MG
Hypidone hydrochloride is the hydrochloride salt of a small-molecule research compound reported to act as a 5-HT receptor agonist with antidepressant-like activity in preclinical studies. Supplied for laboratory research use only; consult the safety data sheet for handling and storage.
- Hydrochloride salt, suitable for research applications.
- Reported 5-HT receptor agonist activity in preclinical models.
- High purity (>99.7%).
- Molecular weight 334.84 g/mol.
- Available in small research pack sizes, e.g., 25 mg.
- Includes datasheet and SDS for safety and handling.
Medchemexpress LLC 1,1'-biphenyl-bis(methylene) bis(4-(4-chlorophenyl)methylamino-quinolinium) dibromide | 850807-63-5 | 98.4% | 877.53 g/mol | C46H38Br2Cl2N4 | 100 MG
RSM-932A is a research small-molecule inhibitor of choline kinase alpha (ChoKα) developed for preclinical oncology studies. It exhibits selective enzymatic inhibition, antiproliferative activity across multiple tumor-derived cell lines, and antitumor efficacy in xenograft models. Supplied as a solid for laboratory research.
- Specific inhibitor of choline kinase alpha.
- Enzyme IC50: ~1 μM for ChoKα and ~33 μM for ChoKβ.
- In vitro antiproliferative activity with IC50s ≈1.3-7.1 μM across cell lines.
- Demonstrated antitumor efficacy in xenograft models.
- High supplied purity (~98.4%) and storage stability when sealed and protected from moisture and light.