Tetrahydrofuran
Medchemexpress LLC DS08210767 | 2376334-75-5 | 99.4% | 513.67 | C31H39N5O2 | 25MG
DS08210767 is a small-molecule antagonist of the parathyroid hormone receptor 1 (PTHR1) for research use. It is reported to be orally bioavailable and shows an in vitro IC50 of 90 nM against PTHR1. The compound is supplied as a light yellow to yellow solid with high reported purity and is intended for biochemical and cellular studies; follow manufacturer storage recommendations.
Medchemexpress LLC D-α-tocopherylquinone | 7559-04-8 | MFCD00135657 | 98.9% | 446.71 | C29H50O3 | 10 MG
- Oxidation product of α-tocopherol with quinone structure.
- Exhibits antioxidant and anticoagulant activity.
- Reduces oxidative damage from oxidized lipids.
- Interacts with glutathione-S-transferase (GST).
- Used in reactive oxygen species (ROS) and lipid peroxidation research.
- Molecular formula C29H50O3; MW 446.71 Da.
Medchemexpress LLC Zectivimod | 1623066-63-6 | 99.35% | 528.47 | 50 MG
Zectivimod is a sphingosine-1-phosphate receptor agonist. It can be utilized in the research of autoimmune diseases, chronic inflammatory diseases, and immunoregulation disorders.
- Sphingosine-1-phosphate receptor agonist
- Research applications in autoimmune diseases
- Research applications in chronic inflammatory diseases
- Research applications in immunoregulation disorders
![Medchemexpress LLC 2-[[4-(diethylamino)-2-hydroxyphenyl]methylene]hydrazide-4-pyridinecarboxylic acid | 140405-36-3 | 99.7% | 312.37 | C17H20N4O2 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000247220.png-250.jpg)
Medchemexpress LLC 2-[[4-(diethylamino)-2-hydroxyphenyl]methylene]hydrazide-4-pyridinecarboxylic acid | 140405-36-3 | 99.7% | 312.37 | C17H20N4O2 | 25 MG
RSVA405 is a potent, orally active activator of AMP-activated protein kinase (AMPK) used in preclinical research. It facilitates CaMKKβ-dependent AMPK activation, inhibits mTOR, promotes autophagy and lysosomal degradation of Aβ, and exhibits anti-inflammatory effects via STAT3 inhibition. Activity is observed in vitro (EC50 ≈ 1 μM) and in vivo in metabolic and renal models.
- Potent AMPK activator with an EC50 of approximately 1 μM.
- Promotes autophagy and lysosomal degradation of Aβ.
- Inhibits mTOR and modulates adipocyte differentiation.
- Exhibits anti-inflammatory effects through STAT3 inhibition.
- Demonstrated in vitro and in vivo activity in metabolic and renal models.
- Supplied as a light yellow to yellow solid with high purity.
eMolecules 121138-01-0 | 3-Iodotetrahydrofuran | Accela ChemBio (ASD) | MFCD09878873 | 198.003 | C4H7IO | 98.000 | IC1CCOC1 | 10g | 666596995
3-Iodotetrahydrofuran | Accela ChemBio (ASD) | 121138-01-0 | MFCD09878873 | 198.003 | C4H7IO | 98.000 | IC1CCOC1 | 10g | 666596995
Medchemexpress LLC CUR61414 | 334998-36-6 | 99.04% | 550.69 | 100 MG
CUR61414 is a novel, potent, and cell-permeable Hedgehog signaling pathway inhibitor. It is a small-molecule aminoproline compound that selectively binds to smoothened (Smo). This compound can induce apoptosis in cancer cells without affecting neighboring non-tumor cells.
- Potent and cell-permeable Hedgehog signaling pathway inhibitor.
- Selectively binds to smoothened (Smo).
- Induces apoptosis in cancer cells.
- Spares neighboring non-tumor cells.
- Exhibits an IC50 of 100-200 nM.
Medchemexpress LLC Hypidone hydrochloride | 1339058-04-6 | 99.7% | 334.84 g/mol | C18H23ClN2O2 | 25 MG
Hypidone hydrochloride is the hydrochloride salt of a small-molecule research compound reported to act as a 5-HT receptor agonist with antidepressant-like activity in preclinical studies. Supplied for laboratory research use only; consult the safety data sheet for handling and storage.
- Hydrochloride salt, suitable for research applications.
- Reported 5-HT receptor agonist activity in preclinical models.
- High purity (>99.7%).
- Molecular weight 334.84 g/mol.
- Available in small research pack sizes, e.g., 25 mg.
- Includes datasheet and SDS for safety and handling.
Medchemexpress LLC Esculentoside H | 66656-92-6 | 98.7% | 989.10 g·mol⁻¹ | C48H76O21 | 10 MG
Esculentoside H is a triterpenoid saponin isolated from Phytolacca esculenta and reported as an NF-κB inhibitor with demonstrated anti-tumor activity. It is supplied as a white to off-white solid for research use in biochemical and cell-based studies.
- High purity: 98.7%
- CAS number: 66656-92-6
- Molecular formula: C48H76O21
- Molecular weight: 989.10 g·mol⁻¹
- Solubility: soluble in DMSO (≈100 mg/mL; hygroscopic)
- Storage: store at 4°C; protect from light; in solution store at -80°C (6 months) or -20°C (1 month)
- Pack size: 10 mg
Medchemexpress LLC Resorcinolnaphthalein | 41307-63-5 | 99.9% | 10 MG
Resorcinolnaphthalein is a small-molecule research reagent that functions as an angiotensin-converting enzyme 2 (ACE2) enhancer. It is supplied as a solid with high reported purity and is intended for laboratory research use only.
- CAS number 41307-63-5.
- Molecular formula C24H14O5.
- Molecular weight 382.36 g/mol.
- Purity 99.9% (reported).
- Appearance solid, light yellow to orange.
- Biological activity ACE2 enhancer; EC50 19.5 μM.
- Storage recommendations: powder -20°C up to 3 years, 4°C up to 2 years; in solvent -80°C up to 2 years, -20°C up to 1 year.
Medchemexpress LLC Resorcinolnaphthalein | 41307-63-5 | 99.9% | 100 MG
Resorcinolnaphthalein (CAS 41307-63-5) is a synthetic spiro dye used as a biochemical reagent for colorimetric and enzymatic assays. Supplied as a dry solid, it is intended for analytical and research applications; handle according to the SDS and COA.
Medchemexpress LLC Nelonicline (ABT-126) | 1026134-63-3 | 99.8% | 313.42 | 100 MG
Nelonicline (ABT-126) is an orally active and selective α7 nicotinic receptor agonist with high affinity to α7 nAChRs in human brain (Ki=12.3 nM). It is utilized for the research of schizophrenia and Alzheimer's disease.
- Orally active and selective α7 nicotinic receptor agonist
- High affinity to α7 nAChRs in human brain
- Activates currents in Xenopus oocytes expressing recombinant human α7 nAChRs
- Used for research of schizophrenia and Alzheimer's disease
- Binds to α3β4* nAChRs in human IMR-32 neuroblastoma cells
- Acts as a 5-HT3 receptor antagonist
Medchemexpress LLC 5-amino-6-methoxy-2-(3',4',5'-trimethoxyphenylsulfonyl)quinoline | 1346169-92-3 | MFCD32174244 | 99.6% | 404.44 | C19H20N2O6S | 25 MG
A quinoline-derived research compound that acts as a microtubule-depolymerizing agent. It inhibits tubulin polymerization, induces mitotic arrest and c-Jun N-terminal kinase-mediated apoptosis, and can sensitize resistant cancer cell lines to mTOR pathway inhibitors. Supplied as a solid for laboratory research use.
- Microtubule-depolymerizing activity observed in cell assays.
- Induces mitotic arrest and JNK-mediated apoptosis.
- High purity (~99.6%) for reproducible results.
- Molecular weight 404.44; formula C19H20N2O6S.
- Soluble in DMSO at 100 mg/mL; ultrasonic agitation recommended.
- Available in small sample sizes (5 mg-100 mg); powder storage at -20°C.
eMolecules 13861-97-7 | 4,4-dimethyltetrahydrofuran-2-one | Pharmablock | MFCD01725854 | 114.144 | C6H10O2 | 97.000 | CC1(C)COC(=O)C1 | 25mg | 592923253
4,4-dimethyltetrahydrofuran-2-one | Pharmablock | 13861-97-7 | MFCD01725854 | 114.144 | C6H10O2 | 97.000 | CC1(C)COC(=O)C1 | 25mg | 592923253
Medchemexpress LLC GSK3182571 | 2135595-04-7 | 99.8% | 495.02 g/mol | C25H31ClN8O | 50MG
GSK3182571 is a non-selective, broad-spectrum pan-kinase inhibitor provided as a solid powder for research use. It is intended for in vitro and cell-based studies to probe kinase networks and off-target effects; not for human use.
- High purity (99.75%).
- Molecular weight 495.02 g/mol.
- Molecular formula C25H31ClN8O.
- Soluble in DMSO at 100 mg/mL (202.01 mM) with ultrasonic aid and pH adjustment.
- Recommended storage: powder -20°C (up to 3 years) or 4°C (up to 2 years).
- White to light yellow solid appearance.