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Organic compounds that are derived from or have a benzene group in their molecular structure. Benzene is an aromatic organic molecule composed of 6 carbon atoms and 6 hydrogen atoms that form a ring. Includes derivatives and substituted molecules.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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7-Chlorokynurenic acid sodium salt is the sodium salt form of a potent and selective antagonist of the glycine co-agonist site on the NMDA receptor. Supplied for research use, the compound is intended for biochemical and pharmacological studies where selective NMDA modulation and water-soluble formulations are required.
Potent and selective antagonist of the NMDA glycine site.
Sodium salt form with improved aqueous solubility.
High purity suitable for research applications.
Soluble in water and DMSO, facilitating preparation of stock solutions.
Recommended short-term storage at 4°C under inert atmosphere; long-term storage in solvent at -80°C.
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FR194738 is a small-molecule squalene epoxidase inhibitor for preclinical research. It inhibits squalene epoxidase activity in HepG2 cell homogenates (IC50 = 9.8 nM) and is provided with analytical characterization suitable for biochemical and cellular studies.
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LM22A-4 is a synthetic small-molecule partial agonist of the tyrosine kinase receptor B (TrkB) used in neurobiology and neurological disease research. Supplied as a powder, it can be prepared into 10 mM stock solutions; its CAS number is 37988-18-4, molecular formula C15H21N3O6, and molecular weight 339.34 g/mol. For research use only.
Specific agonist of tyrosine kinase receptor B (TrkB).
Supplied as a powder for preparation of stock solutions.
Soluble in water ≥50 mg/mL and DMSO ≥29 mg/mL.
Includes recommended volumes for preparing 10 mM stock solutions.
Recommended storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (2 years).
Intended for research use only; not for clinical or human use.
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CPI-455 is a potent pan-KDM5 (histone lysine demethylase 5) inhibitor used in research to increase H3K4 trimethylation and to study mechanisms of drug tolerance in cell models. Supplied as a white to off-white solid for in vitro and preclinical investigations, it should be handled and stored according to laboratory safety guidelines.
Inhibits KDM5 with low nanomolar potency.
Elevates global H3K4me3 levels in treated cells.
Reduces drug-tolerant persister cell populations in models.
Provided as a solid with defined stability and storage conditions.
Available in small research pack sizes suitable for assay work.
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Imiloxan hydrochloride is a potent, selective α2B-adrenoceptor antagonist used in pharmacological research to probe α2-adrenergic receptor subtype function. It is supplied as a characterized solid with defined purity and molecular weight for use in receptor-binding studies, in vitro assays, and in vivo experiments.
Selective α2B-adrenoceptor antagonist
High purity suitable for research applications
Supplied in small research pack sizes for lab use
Supported by analytical data (HNMR, LC-MS)
Provided with SDS, COA, and handling instructions
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Anpirtoline hydrochloride is the hydrochloride salt of anpirtoline, a potent, centrally acting 5-HT1B receptor agonist used in neuroscience research. It displays activity across serotonin receptor subtypes and is supplied as a high-purity research reagent for pharmacology and biochemical assays.
Potent 5-HT1B receptor agonist (Ki ≈ 28 nM).
Also shows activity at 5-HT1A and 5-HT2 receptors (Ki ≈ 150 nM and 1.49 μM).
Purity 99.86% for reproducible experimental results.
Suitable for in vitro and in vivo pharmacology studies.
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Lurasidone (Hydrochloride) acts as an antagonist for dopamine D2 and 5-HT7 receptors, with IC50s of 1.68 nM and 0.495 nM, respectively. It also functions as a partial agonist for the 5-HT1A receptor, exhibiting an IC50 of 6.75 nM.
Shows higher affinity for dopamine D2 and 5-HT2A receptors compared to other antipsychotics tested.
Dose-dependently increases the DOPAC/dopamine ratio in both the frontal cortex and striatum, with a more pronounced effect on the frontal cortex at higher doses.
Dose-dependently inhibits conditioned avoidance response (CAR) in rats.
Dose-dependently inhibits TRY-induced forepaw clonic seizure and p-CAMP-induced hyperthermia.
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Bis(3,5-di-tert-butylphenyl) phosphine oxide is a phosphine oxide used as a drug intermediate and research reagent in organic synthesis. It is typically supplied in small lab-scale quantities for use as a building block in medicinal chemistry and specialty materials synthesis.
Cas number 325773-65-7.
Molecular formula C28H43OP.
Molecular weight about 426.61 g/mol.
Used as a drug intermediate and research chemistry reagent.
Available in small pack sizes (examples: 100 mg, 250 mg, 500 mg, 1 g).
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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