Phenylpropanoids and polyketides
Medchemexpress LLC Genistin | 529-59-9 | 432.38 | 50 MG
Genistin is an isoflavone from the phytoestrogen family. It functions as a potent anti-adipogenic and anti-lipogenic agent. This compound has demonstrated the ability to attenuate cellular growth and promote apoptotic cell death in breast cancer cells by modulating the ERalpha signaling pathway.
- Potent anti-adipogenic and anti-lipogenic agent
- Attenuates cellular growth
- Promotes apoptotic cell death in breast cancer cells
- Modulates the ERalpha signaling pathway
Medchemexpress LLC Genistin | 529-59-9 | 432.38 | 200 MG
Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. It attenuates cellular growth and promotes apoptotic cell death in breast cancer cells through modulation of the ERalpha signaling pathway.
- Negatively regulates ERα.
- Down-modulates ER nuclear translocation and DNA binding activity in breast cancer cells.
- Induces apoptosis and suppresses levels of oncogenic markers in MCF-7 cells.
Medchemexpress LLC Biochanin A | 491-80-5 | 98.7% | C₁₆H₁₂O₅ | 500 MG
Biochanin A (Standard) is the analytical standard of Biochanin A, intended for research and analytical applications. It is a naturally occurring fatty acid amide hydrolase (FAAH) inhibitor, demonstrating inhibition of FAAH with IC50s of 1.8, 1.4, and 2.4 μM for mouse, rat, and human FAAH, respectively. This compound serves as an analytical standard and reference standard for assays and is frequently employed in qualitative, quantitative, and methodological research experiments.
- Inhibits FAAH with IC50s of 1.8, 1.4, and 2.4 μM for mouse, rat, and human FAAH
- Used as an analytical standard and reference standard for assays
- Suitable for qualitative, quantitative, and methodological research experiments
- Compatible with techniques such as HPLC, GC, and MS
Sigma Aldrich Fine Chemicals Biosciences Genistein synthtic 98 HPL100MG
Genistein is an isoflavonoid present among Leguminosae family of plants. It is structurally similar to estrogen (estradiol-17).
Cayman Chemical Daidzein Fatty Acids and Deriv
An isoflavone; binds to ERβ (Ki = 2.8 µM) but not ERα up to 1 mM; estrogenic in vitro, increasing ERE-mediated gene transcription via ERβ (EC50 = 2.8 µM); an inhibitor of CAVII and CAXII (Kis = 4.2 and 56 nM, respectively) and selective for them over CAI, II, and IV (Kis = >10,000, >10,000, and 718.7 nM, respectively); reduces tumor growth in a PC3 prostate cancer mouse orthtopic model at 50 mg/kg per day
Sigma Aldrich Fine Chemicals Biosciences (+/-)-Equol >=99.0% (TLC) | 94105-90-5 | MFCD00016662 | 1MG
(+/-)-Equol >=99.0% (TLC) | Purity: >=99.0% (TLC) | Mol Wt: 242.27 | 94105-90-5 | MFCD00016662 | 1MG
Selleck Chemical LLC Flavone S3967-25mg
Flavone (2-Phenylchromone 2-Phenyl-4-chromone 2-Phenyl-4-benzopyron) a class of flavonoids mainly found in spices and red or purple plant foods with antioxidant anti-proliferative anti-tumor anti-microbial estrogenic acetyl cholinesterase anti-inflammatory activities and are also used in cancer cardiovascular disease neurodegenerative disorders etc
Cayman Chemical Necrostatin-1 Inactive Contro
A demethylated variant of necrostatin-1 that inhibits IDO; ~ 100-fold less effective than Nec-1 in inhibiting RIP1 kinase in vitro and 10-fold less potent than Nec-1 in a mouse necroptosis assay; inhibits TNF-induced systemic inflammatory response syndrome in vivo
Medchemexpress LLC Sophoricoside | 152-95-4 | 99.6% | 10 MG
Sophoricoside is an isoflavone glycoside isolated from Sophora japonica and supplied for research use. It has reported anti-inflammatory, anti-cancer, and immunosuppressive activities. The compound has molecular formula C21H20O10, molecular weight 432.38 g/mol, and CAS number 152-95-4. It is provided as a small solid pack (10 mg) with high reported purity (~99.6%).
- Isoflavone glycoside isolated from Sophora japonica.
- Reported anti-inflammatory, anti-cancer, and immunosuppressive effects.
- High reported purity, suitable for analytical and biological research.
- Molecular formula C21H20O10; molecular weight 432.38 g/mol.
- Supplied in small solid packs for laboratory research.
Medchemexpress LLC Dihydrocoumarin (Hydrocoumarin) | 119-84-6 | 148.16 | 50 G
Dihydrocoumarin is a compound found in Melilotus officinalis. It is a yeast Sir2p inhibitor and also inhibits human SIRT1 and SIRT2 with IC50s of 208 μM and 295 μM, respectively.
- Found in Melilotus officinalis.
- Yeast Sir2p inhibitor.
- Inhibits human SIRT1 (IC50 of 208 μM) and SIRT2 (IC50 of 295 μM).
- Induces concentration-dependent inhibition of SIRT1 in an in vitro enzymatic assay.
- Increases cytotoxicity and apoptosis in the TK6 cell line in a dose-dependent manner.
- Increases p53 lysine 373 and 382 acetylation in the TK6 cell line.
Sigma Aldrich Fine Chemicals Biosciences Dihydrocoumarin >=99%, FCC, FG | 119-84-6 | MFCD00006881 | 10KG
Dihydrocoumarin >=99%, FCC, FG | Purity: >=99% | Mol Wt: 148.16 | 119-84-6 | MFCD00006881 | 10KG
Sigma Aldrich Fine Chemicals Biosciences Dihydrocoumarin >=99%, FCC, FG | 119-84-6 | MFCD00006881 | 5KG
Dihydrocoumarin >=99%, FCC, FG | Purity: >=99% | Mol Wt: 148.16 | 119-84-6 | MFCD00006881 | 5KG