Phenylpropanoids and polyketides
Medchemexpress LLC 4-epi-edoxaban tosylate | 2852734-47-3 | 720.26 g/mol | C31H38ClN7O7S2 | 1 MG
4-epi-Edoxaban tosylate is the tosylate salt of the 4-epimer of edoxaban, a small-molecule factor Xa inhibitor used as a research compound. Intended for laboratory research use only; not for human or clinical use.
- Small-molecule factor Xa inhibitor epimer.
- Available as a solid in milligram quantities for research applications.
- Cas number 2852734-47-3; molecular weight 720.26 g/mol.
- Molecular formula C31H38ClN7O7S2.
- Recommended storage sealed at 4°C; in solution store at -80°C for up to 6 months or -20°C for up to 1 month.
- For research use only; not for therapeutic use.
Medchemexpress LLC Brepocitinib (P-tosylate) | 2140301-96-6 | 100.0% | 561.60 | 1 ML
Brepocitinib P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor. It inhibits JAK1 with an IC50 of 17 nM and TYK2 with an IC50 of 23 nM. It also inhibits JAK2 with an IC50 of 77 nM and JAK3 with an IC50 of 6.49 μM. This compound demonstrates in vitro efficacy in inhibiting various STAT pathways and in vivo efficacy by reducing paw volume in an arthritis model.
- Potent dual inhibitor of JAK1 and TYK2
- Specific inhibition of JAK2 and JAK3 at higher concentrations
- In vitro efficacy in inhibiting STAT pathways
- In vivo efficacy in an animal model of arthritis
- Solid, white to off-white color
- Intended for research purposes only
Medchemexpress LLC Butyl diphenyl phosphate | 2752-95-6 | MFCD00411621 | 306.29 g/mol | C16H19O4P | 50 MG
Butyl diphenyl phosphate is an organophosphate compound used primarily as a flame retardant and a plastic additive. This listing is for research-grade reagent quantities supplied with documented chemical identifiers; storage and analytical details are provided in the Certificate of Analysis.
Medchemexpress LLC Cresyl diphenyl phosphate | 26444-49-5 | MFCD00014920 | 97.0% | 340.31 g·mol⁻¹ | C19H17O4P | 100 G
Cresyl diphenyl phosphate is an organophosphate research chemical (CAS 26444-49-5) used in biochemical and developmental biology studies; it disrupts lipid homeostasis in zebrafish embryos. The material is supplied as a colorless to light yellow liquid with a reported purity of 97.0% and a molecular weight of 340.31 g·mol⁻¹.
- Research-grade organophosphate for laboratory studies.
- Disrupts lipid homeostasis in zebrafish embryos, useful for developmental assays.
- High analytical purity suitable for biochemical and assay applications.
- Supplied as a liquid with defined storage recommendations to maintain stability.
- Provided with documented safety and handling guidance for research use only.
Medchemexpress LLC Rac-brassinazole | 224047-41-0 | 5 MG
Rac-brassinazole is a triazole-type inhibitor of brassinosteroid biosynthesis that targets CYP90B and is used in research to modulate BR signaling pathways.
- Triazole-type brassinosteroid biosynthesis inhibitor.
- CAS 224047-41-0.
- Molecular formula C18H18ClN3O.
- Molecular weight 327.81 g/mol.
- Appearance: solid.
- Solubility: DMSO 50 mg/mL; in vivo formulations include DMSO/PEG300/Tween-80/saline and DMSO/corn oil.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
Selleck Chemical LLC Hesperidin methylchalcone
Hesperidin methylchalcone is the Citrus original products with powerful antioxidant activity
Medchemexpress LLC AKT Antibody YA6004 100uL | 100uL
AKT Antibody (YA6004) (YA6004) is a Rabbit-derived and non-conjugated IgG monoclonal antibody targeting to AKT
Medchemexpress LLC (±)-Naringenin | 67604-48-2 | MFCD00870553 | 99.8% | 272.26 | 500 MG
(±)-Naringenin | 67604-48-2 | MFCD00870553 | 99.8% | 272.26 | 500 MG
Aobchem Trans-4 -Hydroxychalcone | 95% | CAS 38239-52-0 | C15H12O2 | 500mg
Trans-4 -Hydroxychalcone | 95% | CAS 38239-52-0 | C15H12O2 | 500mg
Medchemexpress LLC Trans-chalcone | 614-47-1 | 98.8% | 208.26 g·mol⁻¹ | C15H12O | 50g
trans-Chalcone isolated from Aronia melanocarpa skin is a biphenolic core structure of flavonoids precursor trans-Chalcone is a potent fatty acid synthase (FAS) and -amylase inhibitor trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7 trans-Chalcone has antifungal and anticancer activity[1][2][3]
Medchemexpress LLC Naringenin chalcone | 73692-50-9 | MFCD00016762 | 100 MG
Naringenin chalcone is an orally active intermediate in flavonol biosynthesis. It induces apoptosis and inhibits the production of MCP-1 and NO. This compound exhibits anticancer activity against glioblastoma and possesses anti-inflammatory and anti-allergic properties. Intended for research use only.
- Induces apoptosis in glioblastoma cells.
- Inhibits production of MCP-1, TNF-α, and NO in macrophages.
- Increases adiponectin mRNA levels and protein secretion in adipocytes.
- Reduces eosinophilic airway inflammation and airway hyperresponsiveness.
- Suppresses Th2 cytokine production and reduces mucus overproduction.
- Reduces tumor volume and weight in glioblastoma xenograft models.
- Increases plasma adiponectin levels in diabetic mice.
- Inhibits anaphylactic response to IgE-mediated passive cutaneous anaphylaxis.
Medchemexpress LLC (E)-Naringenin chalcone | 25515-46-2 | 5 MG
(E)-Naringenin chalcone is an orally active anti-allergic agent. It also possesses antioxidant and anti-inflammatory activities, and can improve adipocyte functions. It inhibits histamine release from rat peritoneal mast cells.
- Anti-allergic agent: Inhibits histamine release from mast cells and reduces ear-swelling in allergic mice.
- Antioxidant activity: Demonstrated antioxidant properties.
- Anti-inflammatory activity: Inhibits production of TNF-alpha, MCP-1, and nitric oxide by LPS-stimulated macrophages.
- Adipocyte function improvement: Enhances adiponectin production and stimulates PPARγ activity.
- High purity: 98.87%.
- Appearance: Solid, light yellow to yellow.
- Molecular weight: 272.26.
- Chemical formula: C15H12O5.
- Initial source: Plants (Solanaceae, *Solanum lycopersicum L.*).
Medchemexpress LLC Naringenin | 480-41-1 | 99.28% | 272.25 | 25 G
Naringenin is a predominant flavanone that exhibits strong anti-inflammatory and antioxidant activities. It also possesses anti-dengue virus (DENV) activity.
- Inhibits proliferation and induces apoptosis in HepG2 cells.
- Causes cell cycle arrest and increased caspase-3 activity in A431 cells.
- Reduces triglycerides and cholesterol in plasma and liver.
- Lowers adiposity and increases PPARα protein expression in the liver.
Apexbio Technology LLC 4-METHOXYCHALCONE 1-10000mg
4-Methoxychalcone-1 (CAS No 959-33-1) is a flavonoid derivative often studied in the field of biomedical research It originates from the chalcone family known for diverse biological activities Its mechanism of action involves the modulation of key signaling pathways potentially affecting inflammatory and oxidative stress responses In vitro it exhibits biological activity in the nanomolar to low micromolar range showcasing its potency Common applications include studies using various cancer cell lines where it is tested for antiproliferative effects It is also utilized in animal models to explore its therapeutic potential in disease contexts In drug screening it serves as a candidate for evaluating new therapeutic strategies due to its bioactive properties Experimental concentrations typically depend on the specific research design allowing for flexibility in application across different experimental setups ensuring adaptability to varied research objectives
