Phenylpropanoids and polyketides
Cayman Chemical Luteolin Inhibitors
A common dietary phenolic flavone; inhibits soybean and reticulocyte 15-lipoxygenases (IC50 = 0.6 µM); inhibits the release of TNFα from neutrophils; inhibits matrix metalloproteinases
Medchemexpress LLC Luteolin 7-O-glucuronide | 29741-10-4 | 98.7% | 462.36 | C21H18O12 | 10 MG
Luteolin 7-O-glucuronide is a flavone glycoside used as a research reagent to study matrix metalloproteinase (MMP) inhibition and inflammation-related pathways. It is supplied as a light-yellow solid and as a DMSO solution, and is provided at high purity for biochemical assays and analytical standards.
- Cas number: 29741-10-4.
- Molecular weight: 462.36.
- Typical purity: 98.7% (batch level).
- Physical forms: solid and 10 mM solution in DMSO.
- Typical package sizes include 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.
- Common applications: enzymatic inhibition assays and analytical standardization.
Medchemexpress LLC (-)-Epigallocatechin | 970-74-1 | 99.7% | 306.27 | 25 MG
(-)-Epigallocatechin, a major flavonoid in green tea, prevents amyloid fibril formation by binding to unfolded polypeptides and stabilizing their native-like state. It also exhibits antimicrobial effects, eradicating E. faecalis biofilms and reducing virulence through hydroxyl radical induction.
- Most abundant flavonoid in green tea.
- Binds to unfolded native polypeptides.
- Prevents amyloid fibril conversion.
- Stabilizes native-like molecular states.
- Eradicates E. faecalis biofilms.
- Induces hydroxyl radicals in E. faecalis.
- Down-regulates E. faecalis virulence genes.
Medchemexpress LLC (±)-Catechin | 7295-85-4 | 99.5% | 1 G
(±)-Catechin (rel-Cianidanol) is the racemate of the green tea polyphenol Catechin. Catechin has anticancer activity and induces apoptosis. It has two forms: (+)-Catechin and its enantiomer (-)-Catechin. (+)-Catechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM, while (-)-Catechin promotes hBM-MSC adipocyte differentiation.
- Exhibits anti-tumor effects
- Shows anti-obesity and anti-diabetic properties
- Provides anti-cardiovascular and anti-infectious benefits
- Offers hepatoprotective and neuroprotective effects
- Induces adipocyte differentiation
- Increases adiponectin and PPARγ levels
Medchemexpress LLC Catechin-13C3 | 154-23-4 | MFCD15144883 | 293.25 | 1 MG
Catechin-13C3 is a 13C-labeled version of Catechin, a natural antioxidant found in various plants. This compound inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. This stable isotope-labeled compound is valuable for research applications.
- Labeled stable isotope
- Useful for metabolic studies
- Ideal for quantitative analysis
- Suitable for tracking biochemical pathways
Apexbio Technology LLC Epigallocatechin 970-74-1 20mg
Epigallocatechin (CAS 970-74-1) is a naturally occurring polyphenolic compound isolated from green tea It is known to modulate multiple cellular pathways including oxidative stress response and signal transduction primarily through its antioxidant properties and its ability to influence enzyme activities and cellular signaling cascades Soluble in methanol and ethanol epigallocatechin can be stored under cool dry and airtight conditions This compound is widely utilized in biomedical research for investigating its potential roles in cellular protection cancer biology metabolic regulation and as a tool for studying redox-mediated cellular processes
Apexbio Technology LLC (+)-Catechin hydrate 225937-10-0 10mM (in 1mL DMSO)
( )-Catechin hydrate (CAS 225937-10-0) is a plant-derived flavonoid recognized for its antioxidant properties It functions primarily as a free radical scavenger mitigating oxidative stress by neutralizing reactive oxygen species At physiological pH ( )-catechin hydrate has been shown to protect against DNA strand breaks induced by hydroxyl radicals indicating its capacity to prevent free radical-mediated cellular damage This compound is widely utilized in biomedical research to investigate cellular defense mechanisms against oxidative injury and to explore potential therapeutic strategies for conditions associated with oxidative stress
Research Products International Corp Myricetin 25 MG
Myricetin is a naturally occurring flavonol, a flavonoid found in many grapes, berries, fruits, vegetables, herbs as well as other plants.
Apexbio Technology LLC Rutin 153-18-4 10mM (in 1mL DMSO)
Rutin (CAS 153-18-4) is a naturally occurring flavonoid glycoside that can be isolated from Sophora japonica L It exhibits antioxidant and anti-inflammatory activities primarily by scavenging reactive oxygen species modulating signaling pathways related to oxidative stress and inhibiting pro-inflammatory cytokine production Due to its pharmacological profile rutin is utilized extensively in biomedical research to investigate protective effects against cardiovascular dysfunction vascular permeability and inflammation-related conditions It is soluble in heated water methanol ethanol pyridine and alkaline environments and should be stored under cool dry and sealed conditions
Medchemexpress LLC 7-Hydroxyflavone | 6665-86-7 | MFCD00006835 | 50 MG
7-Hydroxyflavone is a flavonoid isolated from *Clerodendrum phlomidis* that exhibits anti-inflammatory activity. It protects renal cells from nicotine-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway. This orally active compound also inhibits PKM2, COX-2, and 5-LOX, and has demonstrated antioxidant activity and efficacy in various animal models.
- Isolated from *Clerodendrum phlomidis*
- Exhibits anti-inflammatory activity
- Protects renal cells from nicotine-associated cytotoxicity
- Inhibits PKM2, COX-2, and 5-LOX
- Orally active
- Reduces malondialdehyde (MDA) and reactive oxygen species (ROS) levels
- Increases superoxide dismutase (SOD) and glutathione (GSH) levels
- Ameliorates ischemia/reperfusion injury
- Improves high-fat diet-induced non-alcoholic fatty liver disease and obesity
- Purity of 99.89%
- Appearance is a white to off-white solid