Phenylpropanoids and polyketides
Medchemexpress LLC Naringenin chalcone | 73692-50-9 | 1 ML
Naringenin chalcone is an orally active intermediate involved in flavonol biosynthesis. It induces apoptosis, inhibits the production of MCP-1 and NO, and exhibits anticancer activity against glioblastoma. This compound also possesses anti-inflammatory and anti-allergic properties.
- Induces apoptosis
- Inhibits the production of MCP-1 and NO
- Exhibits anticancer activity against glioblastoma
- Possesses anti-inflammatory properties
- Possesses anti-allergic properties
- High purity: 98.86%
- Molecular weight: 272.25
- Formula: C15H12O5
- Appearance: Solid, light yellow to orange
Medchemexpress LLC Naringenin chalcone | 73692-50-9 | 1 MG
Naringenin chalcone is an orally active intermediate in flavonol biosynthesis.
Medchemexpress LLC Xanthohumol | 6754-58-1 | 354.40 | 50 MG
Xanthohumol is a prominent flavonoid isolated from hops. It acts as an inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1, and COX-2. It exhibits anti-cancer and anti-angiogenic activities. Additionally, Xanthohumol possesses antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2, and cytomegalovirus (CMV).
- Inhibits diacylglycerol acetyltransferase (DGAT), COX-1, and COX-2.
- Possesses anti-cancer activities.
- Exhibits anti-angiogenic activities.
- Shows antiviral activity against BVDV, rhinovirus, HSV-1, HSV-2, and CMV.
Medchemexpress LLC 4-Methoxycinnamic acid | 830-09-1 | 178.19 | 50 G
4-Methoxycinnamic acid is a natural phenylpropanoid found in A. preissii. This unique compound plays a role in phenylphenalenone biosynthesis. It is intended for research use only.
- Detected as a natural phenylpropanoid
- Involved in phenylphenalenone biosynthesis
- Suitable for research applications
Medchemexpress LLC 5-Hydroxyflavone | 491-78-1 | 99.8% | 238.24 | 50 MG
5-Hydroxyflavone is a flavonoid ligand that has demonstrated no cytotoxic activity against several cell lines, including MCF-7, FaDU, MDA-MB-435S, U87, RPE-1, and HEK293 cells.
- Flavonoid ligand
- No cytotoxic activity against various cell lines
- Solid appearance, light yellow to yellow color
- Soluble in DMSO
- Long-term storage recommended at -20°C for powder and -80°C in solvent
Medchemexpress LLC (-)-Epigallocatechin (Standard) | 970-74-1 | 99.5% | 306.27 | 50 MG
(-)-Epigallocatechin (Standard) is the analytical standard of (-)-Epigallocatechin. It is intended for research and analytical applications. It is the most abundant flavonoid found in green tea and has the ability to bind to unfolded native polypeptides, thereby preventing their conversion to amyloid fibrils. As an analytical standard, it is commonly utilized in qualitative, quantitative, and methodological research experiments involving techniques such as HPLC, GC, and MS.
- Intended for research and analytical applications
- Most abundant flavonoid found in green tea
- Binds to unfolded native polypeptides, preventing amyloid fibril conversion
- Utilized in qualitative, quantitative, and methodological research experiments
- Compatible with techniques such as HPLC, GC, and MS
Medchemexpress LLC Xanthohumol (Standard) | 6754-58-1 | MFCD00210576 | 354.40 | 50 MG
Xanthohumol (Standard) is the analytical standard of Xanthohumol, intended for research and analytical applications. It is a principal flavonoid isolated from hops, acting as an inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1, and COX-2. It exhibits anti-cancer, anti-angiogenic, and antiviral activities against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2, and cytomegalovirus (CMV).
- Analytical standard for research and analytical applications.
- Inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1, and COX-2.
- Exhibits anti-cancer and anti-angiogenic activities.
- Antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2, and cytomegalovirus (CMV).
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
Medchemexpress LLC 3,4,5-Trimethoxycinnamic acid | 90-50-6 | 99.96% | 238.24 | 1 ML
3,4,5-Trimethoxycinnamic acid is a phenylpropanoid isolated from the roots of *Polygala tenuifolia WILLD*. It exhibits an anti-stress effect and prolongs sleeping time in animals. This compound increases the expression of GAD65 and the γ-subunit of the GABAA receptor, but does not affect the amounts of α- or β-subunits. It is for research use only.
- Anti-stress effect
- Prolongs sleeping time in animals
- Increases expression of GAD65 and γ-subunit of GABAA receptor
- For research use only
Medchemexpress LLC Daunorubicin Hydrochloride | 23541-50-6 | 99.7% | 10 MM * 1 ML
Daunorubicin hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. It inhibits DNA and RNA synthesis, acts as a cytotoxin inhibiting cancer cell viability and inducing apoptosis and necrosis. It is also classified as an anthracycline antibiotic. It is utilized in research for infection and various cancers.
- Inhibits DNA and RNA synthesis
- Acts as a cytotoxin to inhibit cancer cell viability
- Induces apoptosis and necrosis
- Anthracycline antibiotic
- Used in research for infection and various cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, and Wilms' tumor
Medchemexpress LLC Methyl-Hesperidin | 11013-97-1 | MFCD01741310 | 98.3% | 624.59 | 50 MG
Methyl-Hesperidin is a vasodilating agent. It is for research use only and not sold to patients.
- Appearance: Solid
- Color: White to light yellow
- Structure classification: Flavonoids, flavonones, phenols, polyphenols
- Initial source: Plants, other families
- Storage: 4°C, protect from light. In solvent: -80°C for 6 months; -20°C for 1 month (protect from light)
- Purity: 98.29%
- Molecular weight: 624.59
- CAS number: 11013-97-1
Cambridge Isotope Laboratories Predominant Bioaccumulative Toxaphene Congeners Parlar 26 50 62 2 ug/mL in nonane 1 2 mL
Predominant Bioaccumulative Toxaphene Congeners Parlar 26 50 62 2 ug/mL in nonane 1 2 mL
Medchemexpress LLC Ferulic acid 4-O-sulfate | 86321-29-1 | 98.07% | 274.25 | 50 MG
Ferulic acid 4-O-sulfate is a metabolite of Ferulic acid that relaxes arteries and lowers blood pressure in mice. This compound causes significant concentration-dependent relaxations in mouse aorta, femoral and saphenous arteries.
- Relaxes arteries and lowers blood pressure
- Suitable for in vitro and in vivo studies
- Significant concentration-dependent relaxations in mouse arteries
Medchemexpress LLC Phosphine, diphenyl-1-pyrenyl- | 110231-30-6 | 95.0% | 386.42 | C28H19P | 50 MG
Diphenyl-1-pyrenylphosphine (DPPP) is a phosphine-based fluorogenic probe used to detect peroxides and lipid peroxidation in biological samples. It exhibits phototriggered aggregation-induced emission/aggregation-caused quenching behavior and is supplied as a solid reagent for research applications.
- Fluorogenic probe that reacts with peroxides to yield a fluorescent product.
- Sensitive detection of lipid peroxidation in cells and tissues.
- Exhibits phototriggered AIE/ACQ transition for enhanced fluorescence control.
- Off-white to light yellow solid, suitable for laboratory handling and storage.
- Store protected from light; stable under recommended cold storage conditions.
Medchemexpress LLC 4H-1-benzopyran-4-one, 2-(4-hydroxyphenyl)- | 4143-63-9 | MFCD00017687 | 97.0% | 238.24 | C15H10O3 | 50 MG
4′-Hydroxyflavone is a flavone derivative supplied as a research-grade chemical for biochemical and pharmacological studies. It inhibits the enzyme aldose reductase (reported IC50 12 μM) and is provided with batch-specific documentation for laboratory use only.
- Inhibits aldose reductase (IC50 = 12 μM).
- High purity: 97.0%.
- Molecular formula C15H10O3; molecular weight 238.24.
- Supplied as a small-molecule reagent for in vitro studies.
- Datasheet and certificate of analysis available.
Medchemexpress LLC 2-oxo-2H-1-benzopyran-3-carboxylic acid | 531-81-7 | MFCD00006852 | 99.9% | 190.15 g/mol | C10H6O4 | 50 G
Coumarin-3-carboxylic acid is a small-molecule research reagent (2-oxochromene-3-carboxylic acid) used as a fluorescent probe for hydroxyl radicals and as a synthetic building block. Supplied as a high-purity solid, it is suitable for in vitro studies and can be formulated for in vivo dosing when required.