Monoterpenoids
Medchemexpress LLC Genipin | 6902-77-8 | 99.8% | 226.23 | 1 ML
Genipin is a natural crosslinking reagent derived from Gardenia jasminoides Ellis fruits. It inhibits UCP2 (uncoupling protein 2) in cells and is suitable for various research applications, including type 2 diabetes research.
- Inhibits UCP2 (uncoupling protein 2) in cells
- Modulates proteins
- Antitumor activity
- Anti-inflammation activity
- Immunosuppression
- Antithrombosis
- Protects hippocampal neurons
Medchemexpress LLC Genipin | 6902-77-8 | MFCD00888600 | 99.8% | 226.23 | 25 MG
Genipin ((+)-Genipin) is a natural crosslinking reagent derived from Gardenia jasminoides Ellis fruits. It inhibits UCP2 (uncoupling protein 2) in cells. This compound exhibits various bioactivities, making it suitable for a range of research applications.
- Modulates proteins
- Antitumor properties
- Anti-inflammation capabilities
- Immunosuppressive effects
- Antithrombosis activity
- Protects hippocampal neurons
- Used for type 2 diabetes research
Medchemexpress LLC (+)-Genipin (Standard) | 6902-77-8 | 226.23 | 50 MG
Genipin (Standard) is an analytical standard and natural crosslinking reagent derived from Gardenia jasminoides Ellis fruits. It is intended for research and analytical applications, inhibiting UCP2 (uncoupling protein 2) in cells. This product shares the same bioactivity profile as Genipin and can be utilized for type 2 diabetes research.
- Protein modulation
- Antitumor properties
- Anti-inflammation
- Immunosuppression
- Antithrombosis
- Protection of hippocampal neurons
Medchemexpress LLC Genipin (Standard) | 6902-77-8 | 97.51% | 226.23 | 100 MG
Genipin (Standard) is the analytical standard of Genipin. This product is intended for research and analytical applications. Genipin is a natural crosslinking reagent derived from *Gardenia jasminoides* Ellis fruits. It inhibits UCP2 (uncoupling protein 2) in cells and has a variety of bioactivities, including modulation on proteins, antitumor, anti-inflammation, immunosuppression, antithrombosis, and protection of hippocampal neurons. It can also be used for type 2 diabetes research.
- Used as an analytical standard for qualitative, quantitative and methodological research experiments.
- Commonly used in HPLC, GC and MS.
Medchemexpress LLC Genipin | 6902-77-8 | MFCD00888600 | >98.0% | 226.23 | C11H14O5 | 10 MG
Genipin is a natural crosslinking reagent derived from Gardenia jasminoides fruits, commonly used in biochemical and materials research. It inhibits uncoupling protein 2 (UCP2) and displays bioactivities including protein modulation, anti-inflammatory, antitumor, immunosuppressive, and neuroprotective effects. Supplied as a high-purity solid suitable for analytical and research applications.
- Natural crosslinking reagent derived from Gardenia jasminoides.
- Inhibits uncoupling protein 2 (UCP2).
- Useful in research areas such as autophagy, metabolic, and neurological disease.
- Purity >98.0%.
- Molecular weight 226.23 g/mol.
- Light yellow to yellow solid powder appearance.
- Storage: powder -20°C (3 years) or 4°C (2 years).
- Available in small pack sizes including 10 mg for analytical use.
Medchemexpress LLC Genipin ((+)-Genipin) | 6902-77-8 | 99.8% | 226.23 | 50 MG
Genipin is a natural crosslinking reagent derived from Gardenia jasminoides Ellis fruits. It inhibits UCP2 (uncoupling protein 2) in cells and exhibits various bioactivities. This product is suitable for research on protein modulation, antitumor, anti-inflammation, immunosuppression, antithrombosis, protection of hippocampal neurons, and type 2 diabetes.
- Inhibits UCP2 in cells
- Exhibits protein modulation, antitumor, anti-inflammation, immunosuppression, antithrombosis, and hippocampal neuron protection
- Useful for type 2 diabetes research
- Increases mitochondrial membrane potential and ATP levels
- Stimulates insulin secretion in pancreatic islet cells
- Activates pathways leading to glucose transporter 4 translocation and increased glucose uptake
- Increases cytochrome c content in the cytosol of treated FaO cells
- Activates caspase-3 and caspase-7, contributing to apoptotic processes
Medchemexpress LLC Genipin (Standard) | 6902-77-8 | 97.5% | 226.23 | 5 MG
Genipin (Standard) is the analytical standard of Genipin, intended for research and analytical applications. It is a natural crosslinking reagent derived from *Gardenia jasminoides* Ellis fruits and inhibits UCP2 (uncoupling protein 2) in cells. Genipin exhibits various bioactivities, including modulation on proteins, antitumor, anti-inflammation, immunosuppression, antithrombosis, and protection of hippocampal neurons. It is also suitable for type 2 diabetes research.
- Used as an analytical standard
- Reference standard supplied assay
- Commonly used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Medchemexpress LLC Ws-383 | 2247544-02-9 | MFCD32182557 | 99.9% | 498.46 | C18H21Cl2N9S2 | 10MG
WS-383 is a potent, selective, and reversible small-molecule inhibitor of the DCN1-UBC12 protein-protein interaction (IC50 = 11 nM). It inhibits Cul3/1 neddylation in cells, resulting in accumulation of cell-cycle regulators p21 and p27 and increased NRF2, and shows cellular activity in relevant cancer cell lines.
- Potent and selective inhibitor with low-nanomolar biochemical potency.
- Cellular inhibition of Cul3 neddylation at low micromolar concentrations.
- Induces accumulation of p21, p27, and NRF2 in treated cells.
- High-purity solid suitable for biochemical and cellular assays.
- Available as solid and as a DMSO solution for cell-based work.
Cayman Chemical Genipin Inhibitors
A protein cross-linking agent isolated from G. jasminoides Ellis; inhibits UCP2 activity; 5 µM genipin increases glucose-stimulated insulin secretion in isolated pancreatic islets chronically exposed to high levels of glucose; induces apoptosis in FaO rat hepatoma cells and human hepatocarcinoma Hep3B cells
Cayman Chemical Genipin Inhibitors
A protein cross-linking agent isolated from G. jasminoides Ellis; inhibits UCP2 activity; 5 µM genipin increases glucose-stimulated insulin secretion in isolated pancreatic islets chronically exposed to high levels of glucose; induces apoptosis in FaO rat hepatoma cells and human hepatocarcinoma Hep3B cells
Medchemexpress LLC WS-383 | 2247544-02-9 | 99.9% | 498.46 g·mol⁻1 | C18H21Cl2N9S2 | 50MG
WS-383 is a potent, selective, and reversible small-molecule inhibitor of the DCN1-UBC12 protein-protein interaction (IC50 = 11 nM). In cellular assays it inhibits Cul3/1 neddylation and induces accumulation of p21, p27, and NRF2. Supplied as a solid with high purity for research use.
- Potent DCN1-UBC12 inhibitor (IC50 = 11 nM).
- Reversible inhibition of the DCN1-UBC12 interaction.
- Inhibits Cul3/1 neddylation in cellular assays.
- Induces accumulation of p21, p27, and NRF2.
- High purity suitable for research applications.
- Solid form with defined storage recommendations.
- Molecular weight 498.46 g·mol⁻1; formula C18H21Cl2N9S2.
Cayman Chemical Genipin Inhibitors
A protein cross-linking agent isolated from G. jasminoides Ellis; inhibits UCP2 activity; 5 µM genipin increases glucose-stimulated insulin secretion in isolated pancreatic islets chronically exposed to high levels of glucose; induces apoptosis in FaO rat hepatoma cells and human hepatocarcinoma Hep3B cells
Cayman Chemical Genipin Inhibitors
A protein cross-linking agent isolated from G. jasminoides Ellis; inhibits UCP2 activity; 5 µM genipin increases glucose-stimulated insulin secretion in isolated pancreatic islets chronically exposed to high levels of glucose; induces apoptosis in FaO rat hepatoma cells and human hepatocarcinoma Hep3B cells
Medchemexpress LLC HY-17389 100mg , Genipin (+)-Genipin CAS:6902-77-8 Purity:98%
Medchemexpress, HY-17389 100mg Genipin (+)-Genipin CAS:6902-77-8 Formula:C11H14O5 Purity:98% Genipin is a cell permeable inhibitor of uncoupling protein 2 (UCP2). Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC WS-383 | 2247544-02-9 | 99.9% | 498.46 g/mol | C18H21Cl2N9S2 | 5MG
WS-383 is a small-molecule, selective, and reversible inhibitor of the DCN1-UBC12 protein-protein interaction. It has a reported IC50 of 11 nM for disrupting DCN1-UBC12 binding, inhibits Cullin3/1 neddylation in cellular assays, and leads to accumulation of p21, p27, and NRF2. Intended for research use in biochemical and cell-based studies.
- Potent DCN1-UBC12 interaction inhibitor (reported IC50 11 nM).
- Selective and reversible mechanism of action.
- Inhibits Cullin3/1 neddylation in cell-based assays.
- Induces accumulation of cell-cycle regulators p21 and p27, and NRF2.
- Supplied in small research pack sizes suitable for assay development.
- High reported purity (99.9%) with recommended storage at 4°C; store in solvent at -80°C for long-term stability.
- 1
- 2