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Filtered Search Results
AdipoGen 5-Nonanol
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Chemical. CAS 623-93-8. Formula C9H20O. MW 133.3. Synthetic. Bulding block for synthesis.
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Medchemexpress LLC Higenamine hydrochloride | 11041-94-4 | 307.77 | 1 ML
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Higenamine hydrochloride (HY-N2037A) is a selective LSD1 inhibitor, isolated from aconite, demonstrating anti-inflammatory and antibacterial activities. It attenuates IL-1β-induced apoptosis through the ROS-mediated PI3K/Akt signaling pathway, protects brain cells from oxygen deprivation, and promotes bone formation in osteoporosis via the SMAD2/3 pathway. This compound is widely used in research for cancer, inflammation, cardiorenal syndrome, and other diseases.
- Selective LSD1 inhibitor
- Exhibits anti-inflammatory activity
- Exhibits antibacterial activity
- Attenuates IL-1β-induced apoptosis
- Protects brain cells from oxygen deprivation
- Promotes bone formation in osteoporosis
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Medchemexpress LLC Cefozopran hydrochloride | 113981-44-5 | MFCD00944908 | >95.0% | 1 ML
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Cefozopran hydrochloride (SCE-2787) is a semi-synthetic, parenteral, fourth-generation cephalosporin antibiotic. This antibiotic demonstrates a broad spectrum of antibacterial activity, effectively inhibiting most gram-negative and gram-positive organisms.
- Semi-synthetic
- Parenteral, fourth-generation cephalosporin
- Broad-spectrum antibacterial activity
- Effectively inhibits most gram-negative organisms
- Effectively inhibits most gram-positive organisms
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AdipoGen Compound E
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Chemical. CAS 209986-17-4. Formula C27H24F2N4O3. MW 490.5. Cell permeable, potent, selective, non-transition state and non-competitive gamma-secretase inhibitor. Notch processing inhibitor. Only weakly affects presenilinase activity.
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Medchemexpress LLC (E)-4-(Naphthalen-2-yl)but-3-en-2-one | 51557-10-9 | 99.9% | 196.24 | 250 MG
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(E)-4-(Naphthalen-2-yl)but-3-en-2-one is a small active molecule that can be used as a building block. It exhibits anti-leukemic activity, inhibiting the proliferation of human chronic myeloid leukemia cell K562 with an IC50 of 7.6 μM.
- Can be used as a building block.
- Exhibits anti-leukemic activity.
- Inhibits the proliferation of human chronic myeloid leukemia cell K562.
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![eMolecules 1782-15-6 | 2-Amino-1-benzo[b]thiophen-2-yl ethanol | Oakwood Chemical | MFCD04038403 | 193.260 | C10H11NOS | 98.000 | NCC(O)c1cc2ccccc2s1 | 100mg | 537678400](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502150999.JPG-250.jpg)
eMolecules 1782-15-6 | 2-Amino-1-benzo[b]thiophen-2-yl ethanol | Oakwood Chemical | MFCD04038403 | 193.260 | C10H11NOS | 98.000 | NCC(O)c1cc2ccccc2s1 | 100mg | 537678400
2-Amino-1-benzo[b]thiophen-2-yl ethanol | Oakwood Chemical | 1782-15-6 | MFCD04038403 | 193.260 | C10H11NOS | 98.000 | NCC(O)c1cc2ccccc2s1 | 100mg | 537678400
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Medchemexpress LLC Paroxetine (hydrochloride) | 78246-49-8 | 100.0% | 1 ML
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Paroxetine hydrochloride is a potent selective serotonin-reuptake inhibitor and a GRK2 inhibitor with an IC50 of 14 μM. It is used in research for depressive disorders and other biological activities.
- Potent selective serotonin-reuptake inhibitor
- GRK2 inhibitor with an IC50 of 14 μM
- Used for research of depressive disorder
- Restrains T cell migration induced by CX3CL1
- Inhibits GRK2 induced activation of ERK
- Reduces pro-inflammatory cytokines in LPS-stimulated BV2 cells
- Inhibits LPS-induced nitric oxide production and iNOS expression in BV2 cells
- Blocks LPS-induced JNK activation
- Attenuates symptoms of CIA rats and prevents histological damage of joints
- Reduces myocyte cross-sectional area in rats and ROS formation
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AdipoGen TetraMe-1 8-naphthalindiamine
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Chemical. CAS 20734-58-1. Formula C14H18N2. MW 214.31. 1,8-Bisdimethylaminonaphthalene Proton Sponge is an organic compound that has several very interesting properties. One is its very high basicity, another is its spectroscopic properties. It is a very strong base with weak nucleophilic character due to steric effects. Due to this it has been used in organic synthesis as a highly selective non-nucleophilic base. Proton sponge also exhibits a very high affinity for boron, and is capable of displacing hydride from borane to form a boronium-borohydride ion pair.
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Medchemexpress LLC Fomepizole hydrochloride | 56010-88-9 | 99.9% | 1 ML
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Fomepizole (4-Methylpyrazole) hydrochloride is a potent and orally active cytochrome P450 (CYP2E1) inhibitor. It is a competitive inhibitor of the enzyme alcohol dehydrogenase, blocking the conversion of methanol and ethylene glycol to toxic metabolites. It has the potential to be an antidote for ethylene glycol or methanol poisoning.
- Potent and orally active cytochrome P450 (CYP2E1) inhibitor.
- Competitive inhibitor of the enzyme alcohol dehydrogenase.
- Blocks further conversion of methanol and ethylene glycol to toxic metabolites.
- Potential for an antidote for ethylene glycol or methanol poisoning.
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Medchemexpress LLC Epinastine hydrochloride | 108929-04-0 | 99.9% | 1 ML
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Epinastine hydrochloride | 108929-04-0 | 99.9% | 1 ML
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Medchemexpress LLC DYRKs-IN-1 hydrochloride | 1387090-01-8 | 1 ML
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DYRKs-IN-1 is a potent inhibitor of Dual-specificity tyrosine-phosphorylation-regulated kinases (DYRKs). This compound demonstrates antitumor activity, with IC50 values of 5 nM for DYRK1A and 8 nM for DYRK1B. The hydrochloride salt form offers enhanced water solubility and stability.
- Potent inhibitor of DYRK1A (IC50: 5 nM) and DYRK1B (IC50: 8 nM)
- Demonstrates antitumor activity
- Enhanced water solubility
- Increased stability
- Increases cellular potency against human colon tumor cell line SW 620 (EC50: 27 nM)
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Medchemexpress LLC Alprenolol hydrochloride | 13707-88-5 | 99.8% | 500 MG
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Alprenolol hydrochloride is an orally active non-selective β-adrenoceptor antagonist and an antagonist of 5-HT1A and 5-HT1B receptors. It is used as an anti-hypertensive, anti-anginal and anti-arrhythmic agent.
- Orally active non-selective β-adrenoceptor antagonist.
- Antagonizes 5-HT1A and 5-HT1B receptors.
- Used as an anti-hypertensive, anti-anginal, and anti-arrhythmic agent.
- High purity of 99.76%.
- Soluble in DMSO (100 mg/mL) and water (50 mg/mL).
- Formulations available for oral and intraperitoneal injection.
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Medchemexpress LLC Alprenolol (hydrochloride) | 13707-88-5 | 99.8% | 1 ML
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Alprenolol hydrochloride is an orally active non-selective β-adrenoceptor antagonist and an antagonist of 5-HT1A and 5-HT1B receptors. It is used as an anti-hypertensive, anti-anginal, and anti-arrhythmic agent.
- Orally active non-selective β-adrenoceptor antagonist
- Antagonist of 5-HT1A and 5-HT1B receptors
- Functions as an anti-hypertensive agent
- Functions as an anti-anginal agent
- Functions as an anti-arrhythmic agent
- Demonstrates in vivo effects on blood pressure and heart rate in conscious renal hypertensive dogs
- Effectively blocks anxiolytic effects in adult male Swiss Webster mice
- Reduces systolic and diastolic pressure and heart rate in cats
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eMolecules 7150-72-3 | tert-Butyl vinylcarbamate | Ambeed | MFCD00081075 | 143.186 | C7H13NO2 | 98.000 | CC(C)(C)OC(=O)NC=C | 250mg | 600832049
tert-Butyl vinylcarbamate | Ambeed | 7150-72-3 | MFCD00081075 | 143.186 | C7H13NO2 | 98.000 | CC(C)(C)OC(=O)NC=C | 250mg | 600832049
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Medchemexpress LLC MK-571 sodium | 115103-85-0 | MFCD11114392 | 99.8% | 537.07 | 100 MG
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MK-571 sodium (L-660711 sodium) is a potent and selective competitive leukotriene D4 (LTD4) receptor antagonist. It also acts as an inhibitor of multidrug resistance-associated protein MRP4 (ABCC4) and ABCC1 (MRP1). Furthermore, it inhibits constitutive and antigen-stimulated sphingosine-1-phosphate (S1P) release.
- Orally active.
- Potent and selective competitive leukotriene D4 (LTD4) receptor antagonist.
- Inhibits multidrug resistance-associated protein MRP4 (ABCC4) and ABCC1 (MRP1).
- Inhibits constitutive and antigen-stimulated sphingosine-1-phosphate (S1P) release.
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