Naphthalenes
Dansyl-L-valine 98.0+%, TCI America™
CAS: 1098-50-6 Molecular Formula: C17H22N2O4S Molecular Weight (g/mol): 350.433 MDL Number: MFCD00069524 InChI Key: VULDIKGSZAUMHB-INIZCTEOSA-N Synonym: 5-Dimethylaminonaphthalene-1-sulfonyl-L-valine, Dns-Val-OH PubChem CID: 13734194 IUPAC Name: (2S)-2-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]-3-methylbutanoic acid SMILES: CC(C)C(C(=O)O)NS(=O)(=O)C1=CC=CC2=C1C=CC=C2N(C)C
Medchemexpress LLC Spermidine hydrochloride | 334-50-9 | 98.0% | 1 ML
Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzyme activities, and improves photosystem II (PSII) and relevant gene expression. It significantly decreases H2O2 and O2.- contents. It also plays a crucial role against abiotic stresses such as salt, drought, heat, and salinity-alkalinity stresses.
- Maintains cell membrane stability.
- Increases antioxidant enzyme activities.
- Improves photosystem II (PSII) and relevant gene expression.
- Decreases H2O2 and O2.- contents.
- Plays a crucial role against abiotic stresses.
Medchemexpress LLC Adiphenine hydrochloride | 50-42-0 | MFCD00008899 | 99.1% | 1 ML
Adiphenine hydrochloride is a non-competitive inhibitor of nicotinic acetylcholine receptor (nAChR), exhibiting specific IC50s for various receptor subtypes. This compound has also demonstrated anticonvulsant effects in studies.
- Non-competitive inhibitor of nicotinic acetylcholine receptor (nAChR)
- Exhibits anticonvulsant effects
- Blocks function of α1*-nAChR, α3α4*-nAChR, α4β2- and α4β4-nAChR in various cell lines
- Decreases frequency of ACh-induced single-channel currents
- Prevents hindleg tonic-extensor component of maximal electroshock seizures in mice
Medchemexpress LLC BI-671800 | 1093108-50-9 | 99.4% | 501.50 | 1 ML
BI-671800 is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2), with IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. It has potential for the treatment of poorly controlled asthma.
- Hcrth2: 4.5 nM (IC50)
- Mcrth2: 3.7 μM (IC50)
- Exhibits low nM potency as an antagonist of human or mouse CRTH2 in transfected cells.
- Shows significant inhibition of AHR in mice at 0.1-10 mg/kg, i.g.
- Effectively blocks edema formation and greatly reduces inflammatory infiltrate and skin pathology observed in drug vehicle-treated animals.
eMolecules 4-iodo-1,2-dihydro-2,7-naphthyridin-1-one | 959558-50-0 | MFCD17015944 | 1g
Pharmablock | 4-iodo-1,2-dihydro-2,7-naphthyridin-1-one | 1g | 551194113 | PB02093 | | 959558-50-0 | MFCD17015944 | 272.045 | C8H5IN2O
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eMolecules Building Block Tool
Medchemexpress LLC Ald-Ph-PEG6-acid | 2055013-55-1 | 95.3% | 50 MG
Ald-Ph-PEG6-acid is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker; one targets an E3 ubiquitin ligase and the other targets a protein of interest. These molecules work by harnessing the intracellular ubiquitin-proteasome system to selectively degrade target proteins. It appears as a colorless to light yellow viscous liquid.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Targets E3 ubiquitin ligase and a protein of interest
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC SOCE inhibitor 1 | 2169316-15-6 | 99.7% | 513.47 | 50 MG
SOCE inhibitor 1, also known as Compound 39, is a potent store-operated calcium entry (SOCE) inhibitor. It demonstrates good stability in plasma and an IC50 of 4.4 μM, making it suitable for various research applications.
- Potent store-operated calcium entry (SOCE) inhibitor
- IC50 of 4.4 μM
- Good stability in plasma
- White to pink solid appearance
- Purity of 99.73%
- For research use only
Medchemexpress LLC Pf-06446846 hydrochloride | 1632250-50-0 | 99.4% | 10 MM 1 ML
Pf-06446846 hydrochloride is the hydrochloride salt of a small-molecule inhibitor that selectively inhibits translation of PCSK9 by inducing ribosomal stalling; supplied as a 10 mM solution in DMSO for research use. It reduces PCSK9 secretion in Huh7 cells (IC50 ≈ 0.3 μM).
- Hydrochloride salt form, soluble in DMSO and water.
- Targets PCSK9 and inhibits its translation via ribosomal stalling.
- Demonstrated activity in cell assays (Huh7 cells; IC50 ~0.3 μM).
- Supplied as a 10 mM solution in DMSO, 1 mL vial.
- Molecular weight 470.35; formula C22H21Cl2N7O.
- Storage: solid at 4°C; in solvent, -80°C (up to 2 years) or -20°C (up to 1 year).
eMolecules Synthonix - Stock 1-Methyl-5-(tributylstannyl)-1H-pyrazole 10g 525921666 M69898 170682-50-5 MFCD19686983 371.156 C16H32N2Sn
Synthonix - Stock 1-Methyl-5-(tributylstannyl)-1H-pyrazole 10g 525921666 M69898 170682-50-5 MFCD19686983 371.156 C16H32N2Sn
eMolecules Synthonix - Stock 1-Methyl-5-(tributylstannyl)-1H-pyrazole 5g 525921665 M69898 170682-50-5 MFCD19686983 371.156 C16H32N2Sn
Synthonix - Stock 1-Methyl-5-(tributylstannyl)-1H-pyrazole 5g 525921665 M69898 170682-50-5 MFCD19686983 371.156 C16H32N2Sn
eMolecules Synthonix - Stock 1-Methyl-5-(tributylstannyl)-1H-pyrazole 500mg 525932255 M69898 170682-50-5 MFCD19686983 371.156 C16H32N2Sn
Synthonix - Stock 1-Methyl-5-(tributylstannyl)-1H-pyrazole 500mg 525932255 M69898 170682-50-5 MFCD19686983 371.156 C16H32N2Sn
eMolecules Synthonix - Stock 1-Methyl-5-(tributylstannyl)-1H-pyrazole 250mg 508886203 M69898 170682-50-5 MFCD19686983 371.156 C16H32N2Sn
Synthonix - Stock 1-Methyl-5-(tributylstannyl)-1H-pyrazole 250mg 508886203 M69898 170682-50-5 MFCD19686983 371.156 C16H32N2Sn
Medchemexpress LLC NNC-711 hydrochloride | 145645-62-1 | MFCD00153853 | 99.8% | 386.87 g/mol | C21H23ClN2O3 | 50 MG
NNC-711 hydrochloride is a potent, selective inhibitor of the GABA transporter GAT-1 used as a research reagent in neuroscience. It exhibits anticonvulsant and analgesic effects in vivo and is commonly used to study GABA uptake and synaptic inhibition.
- Potent, selective inhibitor of GAT-1 with an IC50 of 0.04 μM (hGAT-1).
- Hydrochloride salt provided as a solid for laboratory use.
- Molecular weight 386.87 g/mol and formula C21H23ClN2O3.
- High purity (~99.8% as listed by the supplier).
- Supplied as a 50 MG research quantity suitable for in vitro and in vivo studies.
Medchemexpress LLC 2-(Naphthalen-1-yl)ethanol | 773-99-9 | MFCD00004050 | 99.9% | 172.22 | C12H12O | 50 G
2-(Naphthalen-1-yl)ethanol (CAS 773-99-9) is an organic research chemical commonly used as a building block and reagent in medicinal chemistry and small-molecule synthesis. It is supplied as a white to off-white solid and is provided with analytical characterization and high reported purity.
- High purity suitable for research (99.88% by HPLC).
- White to off-white solid form for ease of handling.
- Molecular formula C12H12O and molecular weight 172.22.
- Useful as a synthetic building block and intermediate in organic synthesis.
- Characterized by standard analytical data (HPLC, NMR).
Medchemexpress LLC Naphthol AS-MX phosphate | 1596-56-1 | MFCD00042711 | 99.5% | 371.32 g/mol | C19H18NO5P | 50 MG
Naphthol AS-MX phosphate is the phosphate salt used as a chromogenic and fluorogenic substrate for phosphatase-based assays and histochemistry. Supplied as a high-purity solid, it is suitable for enzymatic activity assays, immunoblotting, and histochemical staining; store sealed and protected from moisture, with recommended low-temperature storage for solutions.