Organic phosphoric acids and derivatives
Medchemexpress LLC Diethyl pyrocarbonate | 1609-47-8 | 99.3% | 100 G
Diethyl pyrocarbonate is a potent, orally active, non-specific chemical inhibitor of RNase. It has been useful in vitro as an agent relatively specific for binding to imidazole of histidine. It inhibits central chemosensitivity in rabbits. It can modify Ser, Thr, His, and Tyr residues and be used for modeling. This product is for research use only.
- Potent, orally active, non-specific chemical inhibitor of RNase.
- Useful in vitro as an agent relatively specific for binding to imidazole of histidine.
- Inhibits central chemosensitivity in rabbits.
- Can modify Ser, Thr, His, and Tyr residues.
- Can be used for modeling.
Medchemexpress LLC (E/Z)-3PO | 13309-08-5 | >98% | 210.24 | 100 MG
(E/Z)-3PO is a chemical compound targeting phosphatase, identified as a potent PFKFB3 inhibitor. It plays a role in affecting glycolysis and cancer cell proliferation, making it suitable for research purposes.
- Potent PFKFB3 inhibitor
- Affects glycolysis
- Affects cancer cell proliferation
- Targets phosphatase
Medchemexpress LLC 2-propen-1-one, 3-(3-pyridinyl)-1-(4-pyridinyl)- | 13309-08-5 | 99.9% | 210.24 | 25 MG
The (E/Z)-3PO compound, with chemical formula C13H10N2O and CAS number 13309-08-5, is intended for laboratory research and for use in the manufacture of substances. It is an off-white to light yellow solid, stable under recommended storage conditions, and exhibits a high purity of 99.9% by LCMS. The compound should be handled by experienced personnel in appropriately equipped facilities for research use only.
- Identified for laboratory research applications
- Suitable for substance manufacturing
- Solid appearance, off-white to light yellow
- Melting point between 144-147 °C
- Boiling point range of 387.8±42.0 °C at 760 mmHg
- Stable under recommended storage conditions
- Molecular weight of 210.24
Medchemexpress LLC 1,2-Dimyristoyl-sn-glycerol | 60562-16-5 | 99.96% | 100 MG
1,2-Dimyristoyl-sn-glycerol is a saturated diacylglycerol that acts as a weak second messenger for the activation of Protein Kinase C (PKC). This product is intended for research use only.
- Saturated diacylglycerol compound
- Weak second messenger for protein kinase C activation
- Suitable for biochemical assay research
- Applicable in drug delivery studies
- Used in research for infection, inflammation, and digestive system diseases
Sigma Aldrich Fine Chemicals Biosciences Pyridoxamine 5 phosphate 910MG
Pyridoxamine is a derivative of vitamin B6. Pyridoxamine is a water-soluble vitamin. Vitamin B6 derivatives contain a core pyridine ring. Pyridoxaminecontains an amino methyl group at pyridine 4AE position.
Medchemexpress LLC Dimemorfan phosphate | 36304-84-4 | 99.9% | 100 MG
Dimemorfan phosphate is a sigma 1 receptor agonist that is utilized as a potent antitussive. It is intended for research use only and is not sold to patients.
- Sigma 1 receptor agonist
- Potent antitussive
- Inhibits fMLP- and PMA-induced ROS production in a concentration-dependent manner.
- Suppresses Mac-1 upregulation in PMA- and fMLP-activated groups.
- Significantly suppresses LPS-induced ROS and NO production, and LPS-induced iNOS protein expression.
- Blocks the degradation of cytosolic Iκ-Bα and nuclear translocation of NF-κB p65, as well as the transcriptional activity of NF-κB.
- Attenuates BAY k-8644-induced convulsive behaviors and increases in c-fos and c-jun protein expression in a dose-dependent manner.
- Suppresses the increase of plasma TNF-α levels and inhibits infiltration of neutrophils and production of oxidative stress induced by LPS in lung and liver.
Apexbio Technology LLC 3PO(Synonyms: 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one, 3-(3-Pyridyl)-1-(4-pyridyl)-2-propen-1-one), 10mg, CAS: 13309-08-5; 18550-98-6.
3PO (CAS 13309-08-5 18550-98-6) is a small molecule inhibitor targeting 6-phosphofructo-2-kinase (PFKFB3) a regulatory enzyme involved in cellular glucose metabolism Its mode of action involves inhibiting PFKFB3 activity leading to reduced intracellular synthesis of fructose-2 6-bisphosphate and consequently decreased glycolytic flux By perturbing glucose metabolism 3PO modulates cellular proliferation growth and survival pathways The compound is widely used in cell and animal model studies exploring tumor metabolism metabolic disorders and immunometabolism
Sigma Aldrich Fine Chemicals Biosciences O-Phosphorylethanolamine | 1071-23-4 | MFCD00008178 | 10MG
O-Phosphorylethanolamine | Mol Wt: 141.06 | 1071-23-4 | MFCD00008178 | 10MG
AdipoGen 4-MU phosphate disodium salt
Chemical. CAS 22919-26-2. Formula C10H7Na2O6P. MW 300.11. 4-Methylumbelliferyl phosphate 4-MUP is a fluorogenic substrate for phosphatases mainly alkaline. It is converted to the fluorescent product 4-methylumbelliferone 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively. Therefore, this phosphatase substrate is not well suited for living cell or continuous assays since 4-MU only develops maximum fluorescence at a pH value of >10. Spectral data lambdaex=319nm lambdaem=384nm pH 9.0. lambdaex=360nm lambdaem=449nm for reaction product.
Medchemexpress LLC Pyridoxal phosphate | 54-47-7 | 99.95% | 500 UG
Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia. This product is for research use only.
- Severely inhibits DNA Polymerase and RNase H, leading to an immediate reduction in DNA synthesis.
- Conjugation to pyridoxal phosphate fully inhibits NEIL2.
- Activates the ERK/c-Jun signaling pathway and promotes IGFBP1 protein expression in HepG2 cells.
- Inhibits the proliferation of cancer cells SK-OV-3 and OVCAR-3.
- Alleviates Aβ25-35-induced spatial and long-term memory impairment in mouse models.
- Inhibits the formation of advanced glycation end-products (AGEs) and prevents the progression of diabetic nephropathy.
Medchemexpress LLC Iproniazid phosphate | 305-33-9 | 99.9% | 1 ML
Iproniazid phosphate is an orally active, irreversible, non-selective monoamine oxidase (MAO) inhibitor. It inhibits MAO activity and enhances Rotenone-induced apoptosis. Iproniazid phosphate modulates neurotransmitter levels, affects neuronal function, induces hepatic necrosis, and interferes with the endocrine system. It can be used in the research of depression, Parkinson's disease, and hepatotoxicity.
- Non-selective, irreversible monoamine oxidase (MAO) inhibitor
- Hydrazine class inhibitor
- Has antidepressive activity
- Modulates neurotransmitter levels
- Affects neuronal function
- Induces hepatic necrosis
- Interferes with the endocrine system
- Used in research of depression, Parkinson's disease, and hepatotoxicity
Medchemexpress LLC Iproniazid phosphate | 305-33-9 | 99.92% | 50 MG
Iproniazid phosphate is an orally active, irreversible, non-selective monoamine oxidase (MAO) inhibitor. It inhibits MAO activity, enhances rotenone-induced apoptosis, modulates neurotransmitter levels, affects neuronal function, induces hepatic necrosis, and interferes with the endocrine system. It can be used in the research of depression, Parkinson's disease, and hepatotoxicity.
- Orally active
- Irreversible, non-selective monoamine oxidase (MAO) inhibitor
- Inhibits MAO activity
- Enhances rotenone-induced apoptosis
- Modulates neurotransmitter levels
- Affects neuronal function
- Induces hepatic necrosis
- Interferes with the endocrine system
- Used in research of depression, Parkinson's disease, and hepatotoxicity
Sigma Aldrich Fine Chemicals Biosciences beta-Glycerophosphate disodium salt hydrate <=1.0 mol % L-alpha-isomer | 154804-51-0 | MFCD00149082 | 100G
beta-Glycerophosphate disodium salt hydrate <=1.0 mol % L-alpha-isomer | 154804-51-0 | MFCD00149082 | 100G