Azobenzenes
eMolecules 121219-20-3 | 2,3-Difluoro-4-(n-hexyloxy)phenylboronic acid | Combi-Blocks | MFCD06656273 | 258.070 | C12H17BF2O3 | 98.000 | CCCCCCOc1ccc(B(O)O)c(F)c1F | 1g | 117526294
2,3-Difluoro-4-(n-hexyloxy)phenylboronic acid | Combi-Blocks | 121219-20-3 | MFCD06656273 | 258.070 | C12H17BF2O3 | 98.000 | CCCCCCOc1ccc(B(O)O)c(F)c1F | 1g | 117526294
eMolecules 510772-86-8 | ChemScene | 26-Difluoroterephthalonitrile | 100mg | 599129682 | CS-0088971 | MFCD18806059 | 164.115 | C8H2F2N2
ChemScene | 26-Difluoroterephthalonitrile | 100mg | 599129682 | CS-0088971 | 510772-86-8 | MFCD18806059 | 164.115 | C8H2F2N2
Medchemexpress LLC HSP27 inhibitor J2 | 2133499-85-9 | 99.7% | 264.30 g/mol | C13H12O4S | 25MG
HSP27 inhibitor J2 is a small-molecule research reagent that inhibits heat shock protein 27 (HSP27) by inducing abnormal dimer formation and disrupting HSP27 polymer function. It is supplied as a purified solid for biochemical and cellular studies with documented solubility and storage recommendations.
- High purity (99.7%).
- Molecular weight 264.30 g/mol.
- Chemical formula C13H12O4S.
- Soluble in DMSO at 20 mg/mL (75.67 mM); hygroscopic DMSO may affect solubility.
- Storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (up to 2 years) or -20°C (up to 1 year).
- Available in multiple pack sizes including 25 mg.
Medchemexpress LLC Cdc7-IN-5 | 1402057-86-6 | 96.0% | 100 MG
Cdc7-IN-5 is a potent Cdc7 kinase inhibitor. This compound is extracted from patent WO2019165473A1 and targets Cdc7, a serine-threonine protein kinase enzyme essential for initiating DNA replication in the cell cycle.
- Potent Cdc7 kinase inhibitor
- Extracted from patent WO2019165473A1
- Targets serine-threonine protein kinase enzyme Cdc7
- Essential for DNA replication initiation
- Appearance: solid, white to light yellow
- Molecular weight: 445.47
- Molecular formula: C25H23N3O5
amino]-N-phenyl | 2305052-86-0 | MFCD06761688 | 99.9% | C21H17ClN4O2 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000259801.png-250.jpg)
Medchemexpress LLC 2-pyridinecarboxamide, 5-[[(6-chloro-2-pyridinyl)methyl](1-oxo-2-propen-1-yl)amino]-N-phenyl | 2305052-86-0 | MFCD06761688 | 99.9% | C21H17ClN4O2 | 10MG
BPK-25 is an acrylamide-containing small-molecule research reagent that promotes degradation of nucleosome remodeling and deacetylation (NuRD) complex proteins and inhibits TMEM173 (STING) activation, resulting in modulation of NF-κB signaling. Supplied as a high-purity solid for in vitro and biochemical research; not intended for human use.
- Promotes NuRD complex protein degradation by covalent protein engagement.
- Inhibits STING (TMEM173) activation by the cyclic dinucleotide cGAMP.
- High purity suitable for biochemical assays and in vitro studies.
- Supplied as an off-white to light yellow solid for convenient handling.
- Recommended storage: 4°C under nitrogen; in solvent: -80°C (6 months) or -20°C (1 month).
- For research use only; not for clinical or human use.
eMolecules 2643-85-8 | Medchem Express | Oxypeucedanin hydrate | 5mg | 510478334 | HY-N2622 | MFCD01725702 | 304.298 | C16H16O6
Ambeed | 1-(4-Chlorophenyl)-1H-pyrazole-4-carbaldehyde | 250mg | 600841992 | A507606 | 63874-99-7 | MFCD07643175 | 206.630 | C10H7ClN2O
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Medchemexpress LLC WWL113 | 947669-86-5 | 99.7% | 466.53 | 1 ML
WWL113 is a selective and orally active Ces3 and Ces1f inhibitor, with IC50 values of 120 nM and 100 nM for Ces3 and Ces1f, respectively. It appears to show excellent selectivity for the 60-kDa serine hydrolase (or hydrolases).
- Inhibits mouse recombinant Ces1, Ces1c, and ABHD6 at 10 μM.
- Significantly increases UCP1 protein expression in brown adipocytes at 1 μM.
- Has a partial, statistically significant inhibitory effect on blocking the buildup of PGE2.
- Results in major improvement of multiple features of metabolic syndrome and ameliorated obesity-diabetes in mice with lowered levels of nonesterified free fatty acids (NEFAs), triglycerides (TGs), total cholesterol and fasted glucose as well as enhanced glucose tolerance (30 mg/kg, orally once a day).
- Ameliorates obesity-diabetes in mice.
Medchemexpress LLC PR5-LL-CM01, a protein arginine methyltransferase 5 (PRMT5) inhibitor | 1005307-86-7 | 98.4% | 401.51 | 1 ML
PR5-LL-CM01 is a potent protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC50 of 7.5 μM. It exhibits anti-tumor activities. It has a range of IC50 at 2-4 μM in PDAC cells (PANC1, MiaPaCa2 and AsPC1) and 10-11 μM in CRC cells (HT29, HCT116 and DLD1). PR5-LL-CM01 specifically inhibits cancer cells with low toxicity in normal cells and strongly inhibits colony forming ability in PANC1 and HT29 cells. It also inhibits NF-κB activation and its target gene expression, dramatically decreasing TNFα and IL8 expression in both PANC1 and HT29 cells.
- Potent PRMT5 inhibitor.
- Exhibits anti-tumor activities.
- Low toxicity in normal cells.
- Strongly inhibits colony forming ability in PANC1 and HT29 cells.
- Inhibits NF-κB activation and its target gene expression.
- Decreases TNFα and IL8 expression.
Medchemexpress LLC Cadrofloxacin 25mg | 153808-85-6 | 25 MG
Cadrofloxacin is an orally active fluoroquinolone antibiotic supplied for research use only. It exhibits activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria and is provided as a solid powder for laboratory research and assay development.
- Orally active fluoroquinolone antibacterial agent.
- Active against aerobic and anaerobic Gram-positive and Gram-negative bacteria.
- Supplied as a solid powder suitable for research use.
- Molecular formula C19H20F3N3O4; molecular weight 411.38 g·mol⁻¹.
- Typical purity approximately 98.2% as reported by the manufacturer.
Medchemexpress LLC Catalposide | 6736-85-2 | MFCD28015867 | 1 MG
Catalposide is an iridoid glycoside isolated from Catalpa ovata G. Don (Bignoniaceae). It inhibits TNF-α, IL-1β, and IL-6 productions, and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages. This product is for research use only.
- Solid appearance
- White to yellow color
- Store at 4°C, protect from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protect from light
Medchemexpress LLC 2-Pyridinecarboxamide, 5-[[(6-chloro-2-pyridinyl)methyl](1-oxo-2-propen-1-yl)amino]-N-phenyl | 2305052-86-0 | 98.8% | C21H17ClN4O2 | 100 MG
BPK-25 is an active acrylamide that promotes the degradation of nucleosome remodeling and deacetylation (NuRD) complex proteins through a post-translational mechanism involving covalent protein engagement. It also inhibits TMEM173 activation by the cyclic dinucleotide ligand cGAMP.
- Promotes degradation of NuRD complex proteins.
- Inhibits TMEM173 activation.
- Active acrylamide.
- Intended for research and analytical applications.
Medchemexpress LLC Nimbin | 5945-86-8 | 1 MG
Nimbin is an orally active intermediate limonoid found in Azadirachta. It prevents tau aggregation, increases cell viability, and effectively inhibits the envelope protein of the dengue virus. It shows promise for research in neurodegenerative diseases and viral infections.
- Prevents tau aggregation
- Increases cell viability
- Effectively inhibits the envelope protein of the dengue virus
- Possesses anti-inflammatory, antipyretic, antifungal, antihistamine, antiseptic, antioxidant, anti-cancer, and anti-viral properties
- Promising for research in neurodegenerative diseases and viral infections
Medchemexpress LLC Methylglyoxal-bis(guanylhydrazone) | 459-86-9 | MFCD00067519 | ≥98.0% | 184.20 g·mol⁻¹ | C5H12N8 | 50 MG
Mitoguazone (methylglyoxal-bis(guanylhydrazone)) is a small-molecule research reagent that competitively inhibits S-adenosyl-methionine decarboxylase (SAMDC) and disrupts polyamine biosynthesis. It is used in biochemical and cellular studies to probe polyamine-dependent processes, mitochondrial effects, and apoptosis. Chemical identifiers include CAS 459-86-9, formula C5H12N8, and molecular weight 184.20 g·mol⁻¹.
- Competitive inhibitor of S-adenosyl-methionine decarboxylase (SAMDC).
- Disrupts polyamine biosynthesis for pathway and apoptosis research.
- Reported to be brain-penetrant and useful in cellular assays.
- Characterized chemical identifiers: CAS 459-86-9, formula C5H12N8, MW 184.20 g·mol⁻¹.
- Recommended storage sealed and away from moisture; in solvent: -80°C long-term, -20°C short-term.
- Reported supplier purity commonly ≥98% for research-grade material.
Medchemexpress LLC Corypalmine | 27313-86-6 | 99.5% | 341.40 g/mol | C20H23NO4 | 10 MG
Corypalmine is a naturally occurring isoquinoline alkaloid isolated from Stephania cepharantha. It is reported to exhibit antifungal and antimicrobial activity and is supplied as a high-purity research chemical for biochemical and pharmacological studies.
- Isoquinoline alkaloid chemical class.
- Reported antifungal activity.
- Molecular formula C20H23NO4.
- Molecular weight 341.40 g/mol.
- High purity (99.48%).
- Supplied as a solid powder suitable for laboratory research.
- For research use only; not for human use.
eMolecules 21272-85-5 | Ambeed | Nitromethylphenylsulfone | 250mg | 686660269 | A592579 | MFCD00015928 | 201.2 | C7H7NO4S
Medchem Express | NNMTi | 5mg | 569407541 | HY-131042 | 42464-96-0 | 286.116 | C10H11IN2
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