Azobenzenes
eMolecules 25069-86-7 | 4-(Diphenylamino)phenol | ChemScene | MFCD20259251 | 261.324 | C18H15NO | 98.000 | Oc1ccc(cc1)N(c1ccccc1)c1ccccc1 | 100mg | 536809149
4-(Diphenylamino)phenol | ChemScene | 25069-86-7 | MFCD20259251 | 261.324 | C18H15NO | 98.000 | Oc1ccc(cc1)N(c1ccccc1)c1ccccc1 | 100mg | 536809149
Medchemexpress LLC Iclepertin | 1421936-85-7 | MFCD34474019 | 100.0% | C20H18F6N2O5S | 10MG
Iclepertin is a potent, selective, orally active glycine transporter 1 (GlyT1) inhibitor provided for research use. The compound elevates extracellular glycine and has been investigated for cognitive impairment in neurological disorders; it is intended only for laboratory research and not for human administration.
- Potent, selective glycine transporter 1 (GlyT1) inhibitor.
- Orally active; relevant for in vivo and in vitro studies.
- High chemical purity (99.97%).
- Used in preclinical research on cognitive impairment and schizophrenia.
- Available in small lab-scale pack sizes suitable for experimental workflows.
Medchemexpress LLC GPX4-IN-3 | 2761004-85-5 | 99.8% | C29H24ClN3O3S | 100 MG
GPX4-IN-3 is a potent and selective glutathione peroxidase 4 (GPX4) inhibitor and a selective ferroptosis inducer. It demonstrates significant inhibition of GPX4 and effectively induces ferroptosis in various cell lines, showing a strong ability to increase lipid peroxides. This compound also exhibits antitumor activity and good biological safety in preclinical models, effectively suppressing tumor growth.
- Potent glutathione peroxidase 4 (GPX4) inhibitor
- Selective ferroptosis inducer
- Increases lipid peroxide levels
- Induces ferroptosis with satisfactory selectivity
- Increases reactive oxygen species (ROS) levels in 4T1 cells
- Exhibits antitumor activity
- Good biological safety in vivo
- Suppresses tumor growth in mouse xenograft models
Medchemexpress LLC Benzenesulfonamide, N-[(4-bromophenyl)methyl]-4-chloro-N-[(3R)-hexahydro-2-oxo-1H-aze | 851600-86-7 | 99.5% | C19H20BrClN2O3S | 100 MG
ELN318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor, demonstrating 51-fold selectivity for PS1 with EC50s of 12 nM for PS1 and 656 nM for PS2. It functions as a classic γ-secretase inhibitor, selectively inhibiting Aβ production over Notch signaling in cells. Oral administration *in vivo* leads to an acute reduction of brain Aβ in models of Alzheimer's disease.
- Amyloid precursor protein (APP) selective γ-secretase inhibitor
- Exhibits differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase
- Demonstrates 51-fold selectivity for PS1
- Selectively inhibits Aβ production over Notch signaling in cells
- Displaces an active site directed inhibitor *in vitro*
- Leads to acute reduction of brain Aβ *in vivo* in Alzheimer's disease models
Medchemexpress LLC Regaloside C | 117591-85-2 | 10 MG
Regaloside C is an anti-inflammatory agent and antioxidant that scavenges ABTS and DPPH free radicals. It targets multiple molecules, including TNF-α, MMP-2, ERα, AKT1, TLR4, and HSP90-α, making it applicable for research related to inflammatory diseases.
- Anti-inflammatory agent
- Antioxidant properties
- Scavenges ABTS and DPPH free radicals
- Targets TNF-α, MMP-2, ERα, AKT1, TLR4, and HSP90-α
- Suitable for inflammatory disease research
- Molecular weight of 416.38
- Chemical formula of C18H24O11
- Off-white to yellow solid appearance
- Originates from Gramineae Secale cereale plants
- Potent scavenger of ABTS cationic radicals (IC50 of 139.0 μM)
- Potent scavenger of DPPH anionic radicals (IC50 of 51.6 μM)
Medchemexpress LLC Cadrofloxacin 10mg | 153808-85-6 | 411.38 g·mol^-1 | C19H20F3N3O4 | 10 MG
Cadrofloxacin is a fluoroquinolone antibiotic research compound supplied as a white to off-white solid for laboratory use. It is intended for antibacterial and anti-infection research and is provided with supporting documentation for safe handling and characterization.
- Fluoroquinolone antibiotic used for antibacterial research.
- High purity suitable for analytical and experimental work.
- White to off-white solid powder, convenient for dissolution or formulation.
- Stable when stored frozen as recommended for long-term storage.
- Available with data sheet, certificate of analysis, and safety data sheet.
![Medchemexpress LLC 4-methyl-2-(4-methylpiperazinyl)pyrimido[4,5-b]benzothiazine | 928853-86-5 | 98.5% | 313.42 | C16H19N5S | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000307833.png-250.jpg)
Medchemexpress LLC 4-methyl-2-(4-methylpiperazinyl)pyrimido[4,5-b]benzothiazine | 928853-86-5 | 98.5% | 313.42 | C16H19N5S | 100 MG
4-MMPB (CAS 928853-86-5) is a small-molecule research compound that selectively inhibits 15-lipoxygenase and has been used in studies of cancer biology. It is provided as a high-purity research reagent with characterized activity and recommended storage conditions for long-term stability.
- Selective 15-lipoxygenase inhibitor with reported IC50 ≈ 18 μM.
- High purity suitable for research (≈98.5%).
- Available in small pack sizes for laboratory use, including solid and solution formats.
- Recommended storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); in solvent at -80°C (up to 6 months) or -20°C (up to 1 month).
- Molecular formula C16H19N5S and molecular weight 313.42, suitable for analytical characterization.
Medchemexpress LLC Ombuoside | 20188-85-6 | 5 MG
Ombuoside is a compound with antioxidant properties, capable of inhibiting ROS production and apoptosis. It exhibits neuroprotective effects by acting through the ERK-JNK-caspase-3 system and promotes Dopamine biosynthesis via TH and CREB activation. Additionally, Ombuoside shows antimicrobial activity against various Gram-positive and Gram-negative bacteria, as well as Candida albicans.
- Antioxidant: Inhibits ROS production and apoptosis.
- Neuroprotective: Acts via the ERK-JNK-caspase-3 system.
- Dopamine biosynthesis: Promotes Dopamine biosynthesis through TH and CREB activation.
- Antimicrobial: Exhibits activity against several Gram-positive and Gram-negative bacteria, and Candida albicans.
- Purity: 99.68%.
- Appearance: White to light yellow solid.
- Research use only.
Medchemexpress LLC SU5205 | 98.4% | 100 MG
SU5205 is an inhibitor of VEGFR2 (FLK-1), with an IC50 of 9.6 μM.
- No clinical development reported
![Medchemexpress LLC 1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[5-(pyridin-3-yloxymethyl)-1H-pyrazol-3-yl]urea | 1166393-85-6 | MFCD25977104 | 98.6% | 445.52 g/mol | C24H27N7O2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000299294.png-250.jpg)
Medchemexpress LLC 1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[5-(pyridin-3-yloxymethyl)-1H-pyrazol-3-yl]urea | 1166393-85-6 | MFCD25977104 | 98.6% | 445.52 g/mol | C24H27N7O2 | 10 MG
PF-4618433 is a small-molecule, selective inhibitor of proline-rich tyrosine kinase 2 (PYK2) intended for research use. It exhibits an IC50 of 637 nM against PYK2 and is supplied as a high-purity solid for preclinical assays and exploratory studies in bone-related research.
- Inhibits PYK2 with a reported IC50 of 637 nM.
- High purity: 98.6%.
- Molecular weight 445.52 g/mol.
- Chemical formula C24H27N7O2.
- CAS number 1166393-85-6.
- Supplied as a 10 mg solid for laboratory research.
- Useful for osteoporosis and bone regeneration studies.
![Medchemexpress LLC 2-([1,4'-bipiperidin]-1'-yl)-N-cycloheptyl-6,7-dimethoxyquinazolin-4-amine | 864289-85-0 | 100.0% | 467.65 g/mol | C27H41N5O2 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000244776.png-250.jpg)
Medchemexpress LLC 2-([1,4'-bipiperidin]-1'-yl)-N-cycloheptyl-6,7-dimethoxyquinazolin-4-amine | 864289-85-0 | 100.0% | 467.65 g/mol | C27H41N5O2 | 100 MG
C-021 is a small-molecule CCR4 antagonist developed for research applications in immunology and receptor pharmacology. It is provided as a solid powder with high purity and is used in biochemical assays and functional chemotaxis studies.
- Potent CCR4 antagonist with nanomolar activity.
- High purity suitable for biochemical and cellular assays.
- Supplied as a solid powder for flexible formulation.
- Stable when stored under recommended conditions.
- Appropriate for in vitro and in vivo pharmacology studies.
Medchemexpress LLC Atuliflapon (AZD5718) | 2041075-86-7 | 99.0% | 100 MG
Atuliflapon (AZD5718) is a small-molecule, orally active inhibitor of 5-lipoxygenase activating protein (FLAP) investigated as a research compound for cardiovascular indications such as coronary artery disease. It potently suppresses leukotriene production and has documented preclinical and clinical pharmacology data.
- Oral FLAP inhibitor with potent activity (reported FLAP IC50 ≈ 2 nM).
- Reduces leukotriene production in human whole blood.
- Reported molecular weight 446.50 g·mol⁻¹ and formula C24H26N6O3.
- High purity (about 99.0%), white to off-white solid.
- Soluble in DMSO (≈125 mg/mL); sonication may be required for full dissolution.
- Powder storage: -20°C for long-term stability; in solvent, store at -80°C when possible.