Benzoxadiazoles

Medchemexpress LLC Hexanamide, N-[(1S,2R,3E)-1-[(β-D-glucopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-6-[(7-nitro | 94885-03-7 | 98.0% | 737.88 g·mol⁻¹ | C36H59N5O11 | 100 UG

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C6 NBD Glucosylceramide is a fluorescently labeled glucosylceramide derivative used to investigate sphingolipid metabolism and intracellular trafficking. The NBD fluorophore on a C6 acyl chain provides fluorescence properties suitable for imaging and plate-based assays, and the material is supplied at high purity for biochemical experiments.

• Fluorescent label suitable for microscopy and plate assays.
• Excitation 466 nm and emission 535 nm for standard fluorescence setups.
• High purity suitable for biochemical and enzymatic assays (98.0%).
• Useful for studying glucosylceramide metabolism and internalization.
• Available in small-scale vials ideal for research applications (100 μg, 500 μg).

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Medchemexpress LLC NBD-14189 | 2234273-72-2 | 99.8% | 428.40 | 25 MG

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NBD-14189 is a potent HIV-1 entry antagonist that binds to HIV-1 gp120, exhibiting potent antiviral activity. It demonstrates anti-HIV-1 activity and cytotoxicity in both single-cycle (TZM-bl cells) and multi-cycle (MT-2 cells) assays, and prevents HIV-1 mediated cell-cell fusion.

• Potent HIV-1 entry antagonist (IC50 of 89 nM against HIV-1HXB2 pseudovirus)
• Binds to HIV-1 gp120
• Potent antiviral activity (EC50<200 nM)
• Anti-HIV-1 activity (IC50=0.089 μM) and cytotoxicity (CC50=21.9 μM) in single-cycle assays
• Anti-HIV-1 activity (IC50=0.18 μM) and cytotoxicity (CC50=22.1 μM) in multi-cycle assays
• Prevents HIV-1 mediated cell-cell fusion (IC50=9.4 μM)
• Weak or no inhibition of hERG current (IC50=3.0 μM)

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Medchemexpress LLC 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole | 91366-65-3 | MFCD00036687 | 98.8% | 217.18 | C6H4FN3O3S | 10 MG

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4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole is a fluorescent reagent for the sensitive and specific detection of thiols. It offers low background fluorescence and a stable fluorophore, making it suitable for thiol derivatization and fluorescence-based analytical applications. The compound is typically supplied as a yellow to green solid and should be protected from light during storage.

• Provides sensitive and specific fluorescence-based thiol detection.
• Low fluorescence background for improved signal-to-noise.
• Stable fluorophore under recommended storage conditions.
• Supplied in small, lab-scale quantities for analytical use.
• Yellow to green solid, easy to handle and store.

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Medchemexpress LLC MBD (7-(p-methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole) | 33984-50-8 | 99.6% | C14H12N4O4 | 100 MG

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MBD is a fluorescent probe utilized for investigating protein and nucleoprotein conformation. It has been successfully applied to bacterial ribosomes as well as bovine trypsinogen and trypsin.

• Fluorescent probe for investigating protein and nucleoprotein conformation.
• Successfully applied to bacterial ribosomes, bovine trypsinogen, and trypsin.
• Strong fluorescence when binding to hydrophobic regions of macromolecules.

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Thermo Scientific Chemicals 2,1,3-Benzoxadiazole-5-carbaldehyde, 97%, Thermo Scientific™

2,1,3-Benzoxadiazole-4-carboxaldehyde 98.0+%, TCI America™

CAS: 32863-32-4 Molecular Formula: C7H4N2O2 Molecular Weight (g/mol): 148.12 MDL Number: MFCD07772900 InChI Key: YBBRQAXNTWMMFZ-UHFFFAOYSA-N Synonym: 4-Benzofurazancarboxaldehyde, 4-Formylbenzofurazan PubChem CID: 10290873 IUPAC Name: 2,1,3-benzoxadiazole-4-carbaldehyde SMILES: O=CC1=CC=CC2=NON=C12

6-[[7-(N,N-Dimethylaminosulfonyl)-2,1,3-benzoxadiazol-4-yl]amino]hexanoic Acid 98.0+%, TCI America™

CAS: 1820741-40-9 Molecular Formula: C14H20N4O5S Molecular Weight (g/mol): 356.397 InChI Key: ODEWENLZBOAUCF-UHFFFAOYSA-N Synonym: 4-(5-Carboxypentylamino)-7-(N,N-dimethylaminosulfonyl)-2,1,3-benzoxadiazole PubChem CID: 44629791 IUPAC Name: 6-[[4-(dimethylsulfamoyl)-2,1,3-benzoxadiazol-7-yl]amino]hexanoic acid SMILES: CN(C)S(=O)(=O)C1=CC=C(C2=NON=C12)NCCCCCC(=O)O