Benzoxadiazoles
Medchemexpress LLC Ganglioside GQ1b (bovine) sodium | 68652-37-9 | >98.0% | 2,528.55 g/mol | C106H182N6O56·4Na | 100ug
Ganglioside GQ1b (bovine) sodium promotes neurite outgrowth during early neuronal differentiation Ganglioside GQ1b (bovine) sodium controls the neuronal differentiation process in mESCs[1]
Medchemexpress LLC Nbd-556 | 333353-44-9 | 99.6% | C17H24ClN3O2 | 1 ML
NBD-556, a CD4 mimetic, is a potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction. It demonstrates potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels.
- Potent HIV-1 entry inhibitor
- Blocks gp120-CD4 interaction
- Shows potent cell fusion and virus-cell fusion inhibitory activity
- Inhibits HIV-1 envelope-mediated virus-cell and cell-cell fusion
- Inhibits infection of MT-2 cells by laboratory-adapted HIV-1 strains
- Inhibits CD4-dependent virus in a dose-dependent manner
Medchemexpress LLC C6 NBD glucosylceramide | 94885-03-7 | MFCD00870345 | 98.0% | 737.88 g/mol | C36H59N5O11 | 500 UG
C6 NBD glucosylceramide is a fluorescently labeled short-chain glucosylceramide used as a probe to study sphingolipid metabolism, intracellular trafficking, and glucosylceramide synthase activity. It is provided as a yellow-orange solid for research use and exhibits strong NBD fluorescence for sensitive detection in biochemical and cell-based assays.
- Fluorescent probe with excitation 466 nm and emission 535 nm.
- High purity suitable for biochemical assays.
- Short-chain analog for efficient cellular uptake.
- Stable solid; store protected from moisture and light.
- Compact 500 μg format for small-scale experiments.
Medchemexpress LLC Apelin-16, human, bovine acetate | 99.8% | 2010.37 (free base) | 5 MG
Apelin-16, human, bovine acetate is a biologically active peptide. Apelin is the endogenous ligand for the G-protein-coupled APJ receptor. It is produced as a pre-proprotein of 77 amino acids, and Apelin-16 is one of its active fragments.
- Biologically active peptide
- Endogenous ligand for the G-protein-coupled APJ receptor
- Derived from a pre-proprotein of 77 amino acids
- Active fragment of Apelin
Medchemexpress LLC NBD-556 | 333353-44-9 | 99.6% | C17H24ClN3O2 | 25 MG
NBD-556 is a CD4 mimetic and a potent HIV-1 entry inhibitor. It functions by blocking the gp120-CD4 interaction. NBD-556 exhibits potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels.
- Inhibits HIV-1 envelope-mediated virus-cell and cell-cell fusion.
- Inhibits the infection of MT-2 cells by laboratory-adapted HIV-1 strains.
- Inhibits CD4-dependent virus in a dose-dependent manner.
Medchemexpress LLC NBD-14270 | 2411819-82-2 | 99.53% | 425.43 | 1 ML
NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist with an IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses. It binds to HIV-1 gp120 and demonstrates potent antiviral activity, with low cytotoxicity (CC50>100 μM).
- Potent HIV-1 entry antagonist
- IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses
- Binds to HIV-1 gp120
- Demonstrates potent antiviral activity
- Low cytotoxicity (CC50>100 μM)
Apexbio Technology LLC NBD-F 29270-56-2 100mg
NBD-F (29270-56-2) is a fluorescent derivatization reagent utilized for the detection and quantification of amino acids and low molecular weight amines NBD-F exerts its activity by selectively reacting with primary and secondary amines through its benzofurazan structure forming fluorescent conjugates detectable in biological samples Based on these properties NBD-F holds research potential in biochemical analysis metabolic profiling disease pathology investigation and fluorescent labeling in proteomics and molecular biology
Medchemexpress LLC 6α-ethyl-3α,7α,23-trihydroxy-24-nor-5β-cholan-23-sulfate | 1000403-03-1 | >98.0% | 494.66 g·mol⁻1 | C25H43NaO6S | 50MG
INT-767 is a synthetic dual agonist of the farnesoid X receptor (FXR) and the G protein-coupled bile acid receptor TGR5 (GPBAR1), used as a research reagent in preclinical studies of liver and metabolic disease. Reported activity includes mean EC50s of 30 nM (FXR) and 630 nM (TGR5); CAS 1000403-03-1; molecular formula C25H43NaO6S; molecular weight 494.66 g·mol⁻1. Typical supplier-reported purity is >98%. Material is for research use only and not for human therapeutic use.
- Dual FXR and TGR5 agonist for bile-acid signaling studies.
- Well-characterized potency: EC50 30 nM (FXR) and 630 nM (TGR5).
- High reported purity suitable for in vitro and in vivo experiments.
- Supplied as the sodium-sulfate derivative with defined molecular weight.
- Widely used in preclinical models of liver injury, steatosis, and metabolic regulation.
- For research use only; not for clinical or human use.
Medchemexpress LLC NBD-Cl (NBD chloride) | 10199-89-0 | 99.5% | 1 ML
NBD-Cl is a nonfluorescent reagent that becomes highly fluorescent after reacting with thiol or amino groups. It forms highly fluorescent derivatives for detecting all protein amino acids and provides a simple and sensitive method for determining N-terminal amino acids. It also allows for the identification of prolyl peptides based on fluorescence characteristics.
- Nonfluorescent reagent that becomes highly fluorescent after reaction with thiol or amino groups
- Forms fluorescent derivatives for detection of all protein amino acids
- Simple and sensitive method for determining N-terminal amino acids
- Differences in intensity and color of fluorescence can identify prolyl peptides
- Appearance: Solid, light yellow to yellow
- Excitation (Ex): 498, Emission (Em): 515
- Soluble in DMSO (≥ 100 mg/mL)
- Insoluble in H2O (< 0.1 mg/mL)
Medchemexpress LLC NBD-amine | 10199-91-4 | 96.7% | 50 MG
NBD-amine is a fluorogenic amine used as a fluorescent probe and reagent. It fluoresces weakly in water and strongly in organic solvents, membranes, and other hydrophobic environments, and is supplied as a powder with demonstrated solubility in DMSO.
- Fluorogenic amine that increases fluorescence in hydrophobic environments.
- CAS number 10199-91-4; molecular weight 180.12 g·mol⁻¹; formula C6H4N4O3.
- Purity 96.7% as supplied.
- Soluble in DMSO (≈31.25 mg/mL); hygroscopic DMSO affects solubility.
- Storage: powder -20°C (stable up to 3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Available in multiple package sizes including 50 MG.
Sigma Aldrich Fine Chemicals Biosciences 7-Fluorobenzofurazan-4-sulfonic acid ammonium salt for HPLC derivatization, LiChropur(TM), >=98.5% (HPLC) | 84806-27-9 | MFCD02682109 | 25MG
7-Fluorobenzofurazan-4-sulfonic acid ammonium salt for HPLC derivatization, LiChropur(TM), >=98.5% (HPLC) | Purity: >=98.5% (HPLC) | Mol Wt: 235.19 | 84806-27-9 | MFCD02682109 | 25MG
![Medchemexpress LLC Cholest-5-en-3-ol (3β)-3-[6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoate] | 201731-19-3 | MFCD18428012 | 99.0% | 662.90 g/mol | C39H58N4O5 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000263055.png-250.jpg)
Medchemexpress LLC Cholest-5-en-3-ol (3β)-3-[6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoate] | 201731-19-3 | MFCD18428012 | 99.0% | 662.90 g/mol | C39H58N4O5 | 5 MG
3-C6-NBD-cholesterol is a fluorescently labeled cholesterol analogue used to monitor membrane insertion and intracellular cholesterol trafficking in fluorescence-based assays. The NBD fluorophore attached via a six-carbon linker provides environment-sensitive emission useful for kinetic and localization studies.
- Fluorescent cholesterol analogue for monitoring membrane insertion and intracellular trafficking.
- NBD fluorophore attached via a six-carbon linker for environment-sensitive fluorescence.
- High purity (99.0%) for reproducible experimental results.
- Solid, yellow to orange appearance suitable for handling and formulation.
- Stable as powder at -20°C for long-term storage.
- Provided in small research packs for assay development and optimization.