Benzoxazines
AdipoGen Meranzin
Chemical. CAS 23971-42-8. Formula C15H16O4. MW 260.29. Meranzin is a bioactive compound from the Traditional Chinese Medicine TCM Chaihu-Shugan-San CSS. Meranzin exhibits anti-inflammatory, analgesic and antibacterial activity. Meranzin regulates the alpha 2-adrenoceptor and involves the AMPA-ERK1/2–BDNF signaling pathway. Meranzin has the potential for the prevention of the comorbidity of atherosclerosis and depression.
TARGETMOL CHEMICALS INC CROCONAZOLE 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Croconazole exhibited dose-dependent inhibitory activity on the 5-lipoxygenase (5-LOX) of neutrophils. Croconazole is an antimycotic agent. The IC50s for the synthesis of leukotriene B4 (LTB4) and 5-hydroxyeicosatetraenoic acid (5-HETE) is 7.8 +/- 1.7 andpurity: 99%
TARGETMOL CHEMICALS INC TDI-011536 5MG
Also available in 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. TDI-011536 is a potent Lats kinase inhibitor. TDI-011536 interrupts Hippo-Yap signaling and initiates the proliferation of lesioned heartmuscle cells. TDI-011536 can be used in studies of organ conservation and regeneration. purity: 98%
TARGETMOL CHEMICALS INC A-674563 2HCL552325-73-2 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. A-674563 2HCl is an Akt1 inhibitor with Ki of 11 nM modest potent to PKA and >30-fold selective for Akt1 over PKC.
AdipoGen AZ191
Chemical. CAS 1594092-37-1. Formula C24H27N7O. MW 429.5. Synthetic. Cell permeable azaindole that inhibits the serine/threonine kinase activity of DYRK1B IC50=17nM with 5-fold and 110-fold selectivity against the related family members DYRK1A and DYRK2, respectively. Used as a probe to elucidate the mechanism of DYRK1B regulation of cell cycle progression. Dual-specificity tyrosine-Y-phosphorylation regulated kinase 1B DYRK1B belongs to a family of nuclear-localized protein kinases and participates in the regulation of the cell cycle with key roles in proliferation and differentiation. It is upregulated in solid tumors and gain-of-function mutations in the gene encoding this kinase have been linked to metabolic syndrome.
Cell Signaling Technology Phospho-Stat1 (Tyr701) (58D6) Rabbit mAb (PE-Cy7(R) Conjugate) 100 ul
Phospho-Stat1 (Tyr701) (58D6) Rabbit mAb (PE-Cy7(R) Conjugate) 100 ul
TARGETMOL CHEMICALS INC RAC-NBI-74330 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. rac-NBI-74330 is an effective and selective CXCR3 antagonist. purity: 97%
Cell Signaling Technology FastScan(tm) Total p44/42 MAPK (Erk1/2) ELISA Kit 1 Kit
FastScan(tm) Total p44/42 MAPK (Erk1/2) ELISA Kit 1 Kit
Amsbio LLC MAPTrix™ Screen for Cell Adhesion Assay, 24 different ECM mimetics coated 96 well plate (4 duplicates), 5 plates
MAPTrix™ Screen for Cell Adhesion Assay 24 different ECM mimetics coated 96 well plate (4 duplicates) 5 plates
TARGETMOL CHEMICALS INC QC1 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Qc1 is an inhibitor of threonine dehydrogenase (TDH) inhibitor and can be used in studies about metabolic diseases. purity: 100%
TARGETMOL CHEMICALS INC SUTEZOLID 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Sutezolid (U-100480) is an oxazolidinone antimicrobial for the treatment of tuberculosis. purity: 99%
TARGETMOL CHEMICALS INC ART558 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. ART558 is a potent selective low molecular weight allosteric DNA polymerase activity of Pol(theta) inhibitor (IC50=7.9 nM). ART558 can be used for the research of cancer. purity: 99%
TARGETMOL CHEMICALS INC REC 15/2615 DIHYDROCHLOR 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Rec 15/2615 dihydrochloride is an antagonist of (alpha)1B-adrenergic receptor. purity: 99%
TARGETMOL CHEMICALS INC AG-270 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AG-270 is an allosteric and orally active inhibitor of MAT2A. purity: 98%