Biotin and derivatives
Medchemexpress LLC DOTA-NHS-ester TFA | 95.0% | 10 MG
DOTA-NHS-ester (TFA) is a chemical linker used for affibody molecules. It finds applications in small animal positron emission tomography (PET), single photon emission computed tomography (SPECT), and CT scanning. This product is also suitable for labeling radiotracers or imaging probes for tumor detection.
- Utilized as a linker for affibody molecules
- Applied in small animal positron emission tomography (PET)
- Applied in single photon emission computed tomography (SPECT)
- Applied in CT scanning
- Used to label radiotracers
- Used to label imaging probes for tumor detection
Apexbio Technology LLC Biotin-16-dUTP(Synonyms: Biotin-16-2'-deoxyuridine-5'-triphosphate, Biotin-16-dUTP nucleotide), 10ul (5 mM).
Biotin-16-dUTP is a biotin-labeled nucleotide analog utilized extensively in biomedical research for nucleic acid modification and detection Structurally modified to contain a biotin moiety linked via a 16-carbon spacer this compound functions by enzymatic incorporation into DNA strands mediated by DNA polymerases Following integration the biotin group serves as an affinity tag enabling subsequent detection through biotin-binding proteins such as streptavidin Applications include DNA labeling techniques in fluorescence microscopy and flow cytometry facilitating the visualization and analysis of nucleic acids in vitro
Medchemexpress LLC Biotin-PEG3-NHS ester | 1253286-56-4 | 98.4% | 50 MG
Biotin-PEG3-NHS ester is a PEG-based PROTAC linker, specifically designed for use in the synthesis of PROTACs. Proteolysis Targeting Chimeras (PROTACs) function by leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This compound exhibits a high purity of 98.35%, has a molecular weight of 544.62, and the chemical formula C23H36N4O9S. It is presented as a solid, ranging in color from white to light yellow.
- Functions as a PEG-based linker for the synthesis of PROTACs.
- Enables PROTACs to exploit the intracellular ubiquitin-proteasome system for targeted protein degradation.
- Offers a high purity of 98.35%.
- Molecular weight: 544.62; formula: C23H36N4O9S; CAS No.: 1253286-56-4.
- Available as a solid, with a color ranging from white to light yellow.
Medchemexpress LLC UV Cleavable Biotin-PEG2-Azide | 1192802-98-4 | MFCD28505541 | 95.58% | C38H51N7O9S | 50 MG
UV Cleavable Biotin-PEG2-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Azide group for Cu(I)-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
Medchemexpress LLC Biotin | 58-85-5 | 99.8% | 10 G
Biotin, also known as vitamin B7 or vitamin H, serves as a coenzyme for five carboxylases in humans. It is involved in the synthesis of fatty acids, isoleucine, and valine, as well as in gluconeogenesis. Biotin is essential for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.
- Serves as a coenzyme for five carboxylases in humans
- Involved in the synthesis of fatty acids, isoleucine, and valine
- Involved in gluconeogenesis
- Essential for cell growth
- Essential for the production of fatty acids
- Essential for the metabolism of fats and amino acids
Medchemexpress LLC N3-PEG3-C2-NHS ester | 1245718-89-1 | 99.9% | 344.32 g/mol | C13H20N4O7 | 1 G
N3-PEG3-C2-NHS ester is an azide-terminated PEG3 linker bearing an N-hydroxysuccinimide (NHS) ester reactive group, designed for coupling to primary amines and for use in click-chemistry workflows such as antibody-drug conjugate (ADC) synthesis.
- Azide-terminated PEG3 linker for click chemistry applications.
- NHS ester reactive handle for coupling to primary amines.
- Non-cleavable linker suitable for stable bioconjugation.
- Reported high chemical purity for research use.
- Available in multiple pack sizes including 1 G for laboratory-scale synthesis.
Medchemexpress LLC Fmoc-PEG1-CH2CH2-NHS ester | 1807521-05-6 | 96.3% | 250 MG
Fmoc-PEG1-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteeasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- PROTACs exploit the intracellular ubiquitin-proteasome system
- PROTACs selectively degrade target proteins
Medchemexpress LLC m-PEG14-NHS ester | 00-00-0 | 95.0% | C34H63NO18 | 10MG
m-PEG14-NHS ester is a methoxy-terminated polyethylene glycol (PEG) reagent bearing an N-hydroxysuccinimide (NHS) active ester. Supplied as a solid for laboratory use, it is intended for use as a PROTAC linker or for PEGylation to attach PEG chains to amine-containing molecules via stable amide bonds.
- Methoxy-terminated PEG with an NHS active ester.
- Reacts with primary amines to form stable amide bonds.
- Molecular weight ~773.86 Da.
- Chemical formula C34H63NO18.
- Purity ≥95.0%.
- White to off-white solid appearance.
- Store sealed, away from moisture and light; in solvent: -80°C for 6 months, -20°C for 1 month.
- Available in small research pack sizes.