Cycloheptathiophenes
Medchemexpress LLC Pyrrolidine, 3-(2,3-difluorophenyl)-3-methoxy-, (3S)-, (2E)-2-butenedioate (1:1) | 2251806-70-7 | 98.3% | 329.30 | 25 MG
Pirepemat fumarate (IRL752 fumarate) is a cortical-preferring catecholamine- and cognition-promoting agent. It is used for the study of Parkinson's disease and shows high affinities for 5-HT and NA-related targets. It can reverse deficits resulting from hypomonoaminergic function.
- Cortical-preferring catecholamine- and cognition-promoting agent
- Used for the study of Parkinson's disease
- Shows highest in vitro affinities for 5-HT and NA-related targets
- Reverses deficits from hypomonoaminergic function
- White to off-white solid appearance
- Store at 4°C, sealed and away from moisture
- In solvent, store at -80°C for 6 months or -20°C for 1 month, sealed and away from moisture
Apexbio Technology LLC Fesoterodine Fumarate 286930-03-8 1g
Fesoterodine Fumarate (CAS 286930-03-8) is a synthetic antimuscarinic agent that acts as a competitive antagonist at muscarinic acetylcholine receptors particularly the M3 subtype in the bladder detrusor muscle By inhibiting these receptors the compound modulates involuntary bladder contractions reducing symptoms associated with overactive bladder syndrome such as urgency and frequency Fesoterodine Fumarate is utilized in biomedical research to study cholinergic signaling mechanisms involved in urinary function and to explore pharmacological interventions targeting muscarinic pathways in urological disorders
Medchemexpress LLC Ibutilide (fumarate) | 122647-32-9 | 99.7% | 50 MG
Ibutilide fumarate is an action potential-prolonging antiarrhythmic agent and a potent blocker of the rapidly activating delayed rectifier K+ current (IKr) in AT-1 cells. It is for research use only.
- Potent IKr blocker with an EC50 value of 20 nM at +20 mV in atrial tumor myocytes (AT-1) cells.
- Blocks IKr in cells expressing HERG+MDR1*1 to the same extent as cells expressing HERG alone (IC50: 22.5 nM vs 27.4 nM).
- Cells expressing MDR1*7 show resistance (IC50: 105.3 nM vs 27.4 nM).
- Prolongs cardiac repolarization in vitro and in vivo.
- Cumulative doses (0.01, 0.02, and 0.05 mg/kg i.v., 10-min infusion) resulted in polymorphic and monomorphic non-sustained ventricular tachycardia in animal models.
- Increased action potential duration at 90% (APD90) prolongation in congestive heart failure (CHF) dogs compared to controls at 0.01 mg/kg.
Medchemexpress LLC VUF11207 fumarate | 1785665-61-3 | 99.9% | 586.65 | 50 MG
VUF11207 fumarate is a CXCR7 agonist that binds specifically to CXCR7. It reduces CXCL12-mediated osteoclastogenesis and bone resorption by inhibiting ERK phosphorylation.
- Reduces CXCL12-mediated osteoclastogenesis and bone resorption by inhibiting ERK phosphorylation.
- Binds specifically to CXCR7.
Medchemexpress LLC Fesoterodine fumarate | 286930-03-8 | 99.52% | C30H41NO7 | 5 MG
Fesoterodine fumarate | 286930-03-8 | 99.52% | C30H41NO7 | 5 MG
Medchemexpress LLC Tesmilifene fumarate | 1185241-83-1 | MFCD09878272 | 99.9% | 399.48 g·mol⁻¹ | C23H29NO5 | 1 ML
Tesmilifene fumarate is the fumarate salt of tesmilifene, an H1C receptor antagonist and chemical sensitizer used in oncology research. Supplied as a 10 mM stock solution in DMSO (1 mL), it is intended for in vitro research applications including chemosensitization and cytotoxicity studies.
- Ready-to-use 10 mM stock solution in DMSO
- Concentrated 1 mL volume suitable for multiple assays
- High purity (99.9%) for research use
- Applicable to chemosensitization and cytotoxicity assays
- Provided with molecular weight and CAS identifiers for reporting
Apexbio Technology LLC Fesoterodine Fumarate 286930-03-8 50mg
Fesoterodine Fumarate (CAS 286930-03-8) is a synthetic antimuscarinic agent that acts as a competitive antagonist at muscarinic acetylcholine receptors particularly the M3 subtype in the bladder detrusor muscle By inhibiting these receptors the compound modulates involuntary bladder contractions reducing symptoms associated with overactive bladder syndrome such as urgency and frequency Fesoterodine Fumarate is utilized in biomedical research to study cholinergic signaling mechanisms involved in urinary function and to explore pharmacological interventions targeting muscarinic pathways in urological disorders
Medchemexpress LLC 2-butenedioic-2,3-d2 acid, 1-methyl ester, (2E)- | 253122-44-0 | 98.2% | 132.11 | C5H4D2O4 | 5 MG
Monomethyl fumarate-d2 is the deuterium-labeled analogue of monomethyl fumarate, supplied as a solid research reagent for use in analytical, pharmacological, and metabolic studies. It serves as an internal standard and tracer in mass spectrometry and mechanistic experiments, and represents the active metabolite of dimethyl fumarate (DMF).
- Deuterium labeled for isotope-tracing and mass spectrometry applications.
- High purity suitable for analytical reference and research use.
- Solid form for stable storage and handling.
- Useful as a tracer in metabolic and pharmacokinetic studies.
- CAS 253122-44-0 corresponds to the d2 isotopologue.