Cycloheptathiophenes
Apexbio Technology LLC Ibutilide Fumarate 122647-32-9 10mM (in 1mL DMSO)
Ibutilide Fumarate (CAS 122647-32-9) is a small molecule classified as a Class III antiarrhythmic agent It acts primarily by enhancing slow inward sodium currents and delaying repolarization through inhibition of the rapid component of the cardiac delayed rectifier potassium current (IKr) resulting in prolongation of the cardiac action potential Ibutilide is utilized in research to investigate pharmacological cardioversion of atrial arrhythmias specifically studying the acute conversion of atrial fibrillation and atrial flutter to normal sinus rhythm Its properties make it valuable for exploring the mechanisms of antiarrhythmic therapy and cardiac electrophysiology
Apexbio Technology LLC Quetiapine Fumarate 111974-72-2 10mM (in 1mL DMSO)
Quetiapine Fumarate (CAS 111974-72-2) is a small-molecule atypical antipsychotic with antagonistic activity at dopamine (D1 D2) serotonin (5-HT1A 5-HT2) and adrenergic ( 1 2) receptors In vitro it exhibits affinity for multiple neurotransmitter receptors with dopamine-2 binding characteristics similar to clozapine Preclinical in vivo studies demonstrate antipsychotic effects minimal extrapyramidal side effects and a lower propensity for sustained prolactin elevation Quetiapine has been shown to modulate neurotrophin expression and restore hippocampal neurogenesis following chronic stress in animal models supporting its value in neuropsychiatric and neuropharmacological research
Medchemexpress LLC Monomethyl fumarate | 2756-87-8 | MFCD00063174 | 100.0% | 130.10 g/mol | C5H6O4 | 1 ML
Monomethyl fumarate is the methyl ester of fumaric acid and the active metabolite of dimethyl fumarate; it acts as a GPR109A agonist and is used in biochemical and pharmacological research. The product is offered with high purity and is available as a ready-to-use solution or as solid material for analytical and preparative applications.
- High purity suitable for research applications.
- Provided as a ready-to-use 10 mM solution in DMSO (1 mL).
- Also available in solid form for bulk use or formulation.
- Well-characterized molecular data: chemical formula C5H6O4 and molecular weight 130.10 g/mol.
- Appropriate for use as a reference compound and in studies of GPR109A-mediated pathways.
Selleck Chemical LLC Bedaquiline fumarate S4854-25mg
Bedaquiline fumarate (TMC-207) an oral diarylquinoline is a bactericidal antimycobacterial drug It is a proton-translocating ATP synthetase inhibitor
Medchemexpress LLC Ro 48-8071 fumarate | 189197-69-1 | MFCD05865242 | 99.1% | 564.44 g/mol | C27H31BrFNO6 | 10 MG
Ro 48-8071 fumarate is a potent oxidosqualene cyclase (OSC) inhibitor used in research to block cholesterol biosynthesis and to probe cholesterol-dependent cellular pathways in vitro and in vivo. It is supplied as the fumarate salt at high purity for biochemical and cell-based studies.
- Potent oxidosqualene cyclase inhibitor (IC50 ≈ 6.5 nM).
- Suitable for cell-based and in vivo research applications.
- High purity appropriate for biochemical assays (≈99.1%).
- Provided as the fumarate salt to aid stability and handling.
- Molecular weight 564.44 g/mol for accurate dosing and calculations.
- Supplied in small research pack sizes for screening and mechanistic studies.
Medchemexpress LLC Ocifisertib (fumarate) | 1616420-30-4 | 99.3% | 650.72 g/mol | C37H38N4O7 | 10MG
Ocifisertib fumarate is the fumarate salt of CFI-400945, an orally bioavailable small-molecule inhibitor of Polo-like kinase 4 (PLK4) for preclinical research. It is supplied as a powder for in vitro and in vivo studies and shows low-nanomolar potency against PLK4 and activity against several related kinases.
Selleck Chemical LLC Zilurgisertib fumarate-25MG
Zilurgisertib fumarate(INCB-000928 fumarate NBU-928 fumarate) is a selective ALK 2 inhibitor It is under development for the treatment of heterotopic ossification and fibrodysplasia ossificans progressiva
Medchemexpress LLC Monomethyl fumarate-d2 | 253122-44-0 | MFCD00063174 | 98.2% | 132.11 | C5H4D2O4 | 1 MG
Monomethyl fumarate-d2 is the deuterium-labeled form of monomethyl fumarate, provided as a high-purity research chemical and isotopically labeled standard for metabolic, pharmacological, and analytical studies.
- Deuterium-labeled analog for isotope tracing and mass spectrometry.
- High purity suitable for research applications.
- Supplied in milligram quantities for small-scale experiments.
- Useful as a metabolic standard and mechanistic probe.
TARGETMOL CHEMICALS INC APLINDORE FUMARATE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Aplindore Fumarate (DAB-452) is a small molecule dopamine D2 receptor partial agonist.Aplindore Fumarate exhibits high affinity for dopamine D2 and D3 receptors and low affinity for dopamine D4 5-hydroxytryptophan (5-HT2) and (alpha)1-adrenergic receptors.Aplindore Fumarate is used in the study of Parkinson's disease and schizophrenia. Fumarate can be used to study Parkinson's and schizophrenia. purity: 100%