Dioxolanes
Selleck Chemical LLC Ertugliflozin S5413-25mg
Ertugliflozin (MK-8835 PF-04971729) is a potent and selective sodium-dependent glucose cotransporter 2 inhibitor with IC50 values of 0 877 nM for h-SGLT2 and 1000-fold higher for h-SGLT1
Apexbio Technology LLC Topiramate 97240-79-4 10mM (in 1mL DMSO)
Topiramate (CAS 97240-79-4) is an anticonvulsant compound widely investigated for its interactions with multiple neuronal ion channels and neurotransmitter receptors including AMPA kainate and NMDA glutamate receptors as well as GABA A receptors and voltage-gated Na channels In vitro studies demonstrate that at submicromolar concentrations (IC 0 5 M) topiramate selectively inhibits GluR5-containing kainate receptor-mediated excitatory synaptic currents in rat basolateral amygdala neurons and partially attenuates AMPA receptor-mediated responses Electrophysiological assays in cortical slices reveal that topiramate modulates persistent Na currents and shifts steady-state inactivation In animal models topiramate confers dose-dependent neuroprotection in ischemic stroke and elevates seizure thresholds supporting its utility for mechanistic studies of epilepsy and neuroprotection
Medchemexpress LLC Erythromycin cyclocarbonate | 55224-05-0 | 98.0% | 759.92 g/mol | C38H65NO14 | 25 MG
Davercin (erythromycin cyclocarbonate) is a semi-synthetic derivative of erythromycin used as an antibacterial research reagent. It inhibits bacterial protein synthesis and is active against Gram-positive and some Gram-negative organisms. Supplied as a solid for laboratory studies and analytical reference.
- Derivative of erythromycin with antibacterial activity.
- Active against Gram-positive and some Gram-negative organisms.
- High purity (98.0%).
- Molecular weight 759.92 g/mol and formula C38H65NO14.
- White to off-white solid suitable for laboratory use.
- Available in small research quantities such as 25 MG.
Medchemexpress LLC Erythromycin cyclocarbonate | 55224-05-0 | 759.92 | C38H65NO14 | 1 MG
Davercin (erythromycin cyclocarbonate) is a semi-synthetic macrolide antibiotic derivative used in research to study antibacterial activity and mechanisms of protein synthesis inhibition. It is active primarily against Gram-positive organisms and some Gram-negative strains, and is provided as a characterized reagent for microbiology and pharmacology assays.
- Derivative of erythromycin with macrolide activity.
- Active against Gram-positive and some Gram-negative microorganisms.
- Useful for research on bacterial protein synthesis inhibition.
- Characterized chemically: formula C38H65NO14, molecular weight 759.92 g/mol.
- Supplied in small research quantities suitable for assay development and characterization.
Medchemexpress LLC Dilinoleyl methanol | 1169768-28-8 | MFCD32062843 | 98.0% | C37H68O | 10MG
Dilinoleyl methanol is an ionizable, unsaturated long-chain alcohol used as a lipid component and synthetic intermediate in lipid-based drug delivery systems and in the synthesis of ionizable cationic lipids. It is a liquid lipid (C37H68O, MW 528.94) commonly used in formulation development for lipid nanoparticles.
- Ionizable lipid suitable for lipid nanoparticle formulations.
- Useful synthetic intermediate for ionizable cationic lipid synthesis.
- High purity (98.0%).
- Liquid, colorless to light yellow; density ≈0.864 g/cm3.
- Recommended storage: -20°C for long term; in solvent store at -80°C.
Cayman Chemical IsoquercetIn 10mg
A flavonoid with diverse biological activities; reduces viral titers of H5N1 influenza isolates by 79.66% in a plaque assay at 1 ng/ml; inhibits apoptosis, increases cell viability, and decreases the level of ROS in an oxygen-glucose deprivation/reoxygenation assay in primary rat hippocampal neurons at 25, 50, and 100 UG/ml; decreases TNF-α-induced cell death in primary mouse hepatocytes (IC50 = 37.5 µM); reduces infarct volume and neurological symptoms in a rat model of MCAO at 50 mg/kg