Furans
Medchemexpress LLC MK2-IN-3 hydrate | 1186648-22-5 | ≥99.0% | 358.39 | 10 MG
MK2-IN-3 hydrate (compound 16) is an orally active, selective, and ATP-competitive MAPKAP-K2 (MK-2) inhibitor with an IC50 of 8.5 nM. It exhibits exceptional selectivity against MK-3 (IC50=0.21 μM), MK-5 (IC50=0.081 μM), ERK2 (IC50=3.44 μM), MNK1(IC50=5.7 μM), as well as CDK2, JNK2, IKK2, MSK1, and MSK2. It suppresses TNFα production in U397 cells with an IC50 of 4.4 μM.
- Orally active.
- Selective and ATP-competitive MAPKAP-K2 (MK-2) inhibitor.
- Exceptional selectivity against MK-3, MK-5, ERK2, MNK1, CDK2, JNK2, IKK2, MSK1, and MSK2.
- Suppresses TNFα production in U397 cells with an IC50 of 4.4 μM.
Medchemexpress LLC Dantrolene sodium | 14663-23-1 | 99.8% | 336.23 | 500 MG
Dantrolene sodium is an orally active, non-competitive glutathione reductase and calcium channel protein inhibitor. It inhibits Ca2+ release from RyR1 and RyR3, benefiting pathologies involving calcium homeostasis disruption, such as stroke and neurodegenerative diseases. It also relieves muscle spasms and malignant hyperthermia, with antitoxic, antipyretic, and anti-inflammatory properties.
- Orally active glutathione reductase and calcium channel protein inhibitor
- Inhibits Ca2+ release from RyR1 and RyR3
- Beneficial for calcium homeostasis disruptions
- Relieves muscle spasms and malignant hyperthermia
- Possesses antitoxic, antipyretic, and anti-inflammatory properties
eMolecules 7168-85-6 | ChemScene | 7-Methoxybenzofuran | 1g | 632283589 | CS-0150289 | MFCD01310825 | 148.161 | C9H8O2
ChemScene | 7-Methoxybenzofuran | 1g | 632283589 | CS-0150289 | 7168-85-6 | MFCD01310825 | 148.161 | C9H8O2
Sigma Aldrich Fine Chemicals Biosciences Nitrofurantoin 98.0-102.0% (EP, UV) | 67-20-9 | MFCD00003224 | 25G
Nitrofurantoin 98.0-102.0% (EP, UV) | Purity: 98.0-102.0% (EP, UV) | Mol Wt: 238.16 | 67-20-9 | MFCD00003224 | 25G
Chem-Impex International, Inc. 2,5-Furandicarboxylic acid | MFCD00016582 | 25G
2,5-Furandicarboxylic acid, MFCD00016582, 25G
Alkali Scientific Nitrofurantoin, 5 G
Nitrofurantoin, 5g, is a laboratory-grade antibiotic used to study bacterial resistance, particularly in the context of urinary tract infections (UTIs). It is effective against a broad spectrum of Gram-positive and Gram-negative bacteria by disrupting their protein synthesis, DNA replication, and overall metabolism. The 5g quantity is ideal for use in antimicrobial susceptibility testing, such as Minimum Inhibitory Concentration (MIC) assays, disk diffusion, and other microbiological tests. Nitrofurantoin is also used in research settings to better understand antimicrobial resistance mechanisms, including the development of resistance in UTI pathogens.
Medchemexpress LLC Sonlicromanol | 1541170-75-5 | 99.8% | 10 MG
Sonlicromanol is an orally active reactive oxygen species (ROS) modulator used for mitochondrial disease research. It is provided as a high-purity research reagent with good solubility in DMSO.
- Orally active ROS modulator suitable for mitochondrial disease research.
- High purity, 99.75%.
- Molecular formula C19H28N2O3; molecular weight 332.44 g·mol⁻¹.
- Soluble in DMSO at approximately 25 mg/mL; sonication may be required.
- Packaged as 10 mg for laboratory research use.
Matrix Scientific ETHYL 5-AMINO-1-BENZOFURAN--1G
Ethyl 5-amino-1-benzofuran-2-carboxylate, >95%; 1g,C11H11NO3, MFCD08275091, mw 205.22, [174775-48-5]
Cayman Chemical Mometason Furoate-d3 1mg
An internal standard for the quantification of mometasone furoate by GC- or LC-MS
Medchemexpress LLC Chdi-390576 | 1629729-98-1 | 98.1% | 10 MG
A small-molecule, cell-permeable, CNS-penetrant class IIa histone deacetylase (HDAC) inhibitor for research use. It is suitable for biochemical and cellular assays to study HDAC biology and related pathways. Available as a solid and in ready-to-use DMSO solutions with recommended cold storage.
- Potent inhibition of class IIa HDAC isoforms (reported IC50s: HDAC4 54 nM, HDAC5 60 nM, HDAC7 31 nM, HDAC9 50 nM).
- High selectivity over class I and other HDAC isoforms (>500-fold vs class I; ~150-fold vs HDAC8 and HDAC6).
- High purity supply (approximately 98.1%).
- Supplied as powder and as 10 mM solutions in DMSO; recommended storage: powder -20°C, in solvent -80°C (short term at -20°C).
- Intended for research use only; not for human or diagnostic applications.
![Medchemexpress LLC N2-{[1-ethyl-6-(4-methylphenoxy)-1H-benzimidazol-2-yl]methyl}-L-alanineamide | 1233229-75-8 | 99.4% | 352.43 g/mol | C20H24N4O2 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000221119.png-250.jpg)
Medchemexpress LLC N2-{[1-ethyl-6-(4-methylphenoxy)-1H-benzimidazol-2-yl]methyl}-L-alanineamide | 1233229-75-8 | 99.4% | 352.43 g/mol | C20H24N4O2 | 5 MG
Bliretrigine is a research-stage sodium channel blocker supplied for laboratory studies of pain and neuronal function. It is provided in high-purity solid and solution formats for preclinical experiments and is intended for research use only, not for human therapeutic use.
- Sodium channel blocker with reported analgesic activity.
- High purity suitable for research applications (99.4%).
- Available as powder and as a DMSO solution.
- Stable when stored under recommended conditions for powder and solutions.
- Intended for research use only; not for human use.
eMolecules 1202916-90-2 | Medchem Express | CX-6258 | 5mg | 446268890 | HY-18095 | MFCD28142834 | 461.95 | C26H24ClN3O3
Ambeed | Boc-D-Serinol(Bzl) | 1g | 525186612 | A325274 | 127559-33-5 | MFCD00235944 | 281.352 | C15H23NO4
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Medchemexpress LLC Mk2-in-1 hydrochloride | 1314118-94-9 | 98.4% | 509.43 g/mol | C27H26Cl2N4O2 | 5 MG
MK2-IN-1 hydrochloride is the hydrochloride salt of a small-molecule MAPKAPK2 (MK2) inhibitor intended for biochemical and cell-based research. It provides potent biochemical activity with high solubility and is supplied as a solid for laboratory use.
- Potent and selective MAPKAPK2 (MK2) inhibitor (IC50 = 0.11 μM; EC50 = 0.35 μM).
- High purity (98.36%).
- Molecular formula C27H26Cl2N4O2; molecular weight 509.43 g/mol.
- Solid, light yellow to pink appearance suitable for handling and storage.
- High solubility in water and DMSO (water ≥ 100 mg/mL; DMSO 100 mg/mL).
- Includes recommended in vivo formulation options for dosing studies.
Medchemexpress LLC Nitrofurantoin | 67-20-9 | MFCD00003224 | 99.7% | C8H6N4O5 | 1 ML
Nitrofurantoin is a potent, orally active, broad-spectrum beta-lactamase antimicrobial agent. It functions as an antibiotic, making it suitable for research into urinary tract infections (UTIs), including cystitis and kidney infections.
- Potent broad-spectrum antimicrobial agent
- Antibiotic for urinary tract infection research
- Purity of 99.7%
- Soluble in DMSO (100 mg/mL)
- Light yellow to yellow solid appearance
- For research use only