Furans
Medchemexpress LLC BMS-911172 25mg | 1644248-18-9 | 339.34 g/mol | C16H19F2N3O3 | 25 MG
BMS-911172 is a small-molecule, brain-penetrant inhibitor of adaptor protein 2-associated kinase 1 (AAK1) used as a research compound to investigate AAK1-mediated signaling and neuropathic pain mechanisms. Chemical formula C16H19F2N3O3; molecular weight 339.34 g/mol; reported AAK1 activity in the low-nanomolar range.
- Potent AAK1 inhibition with low-nanomolar activity.
- Brain-penetrant small molecule suitable for in vivo models.
- High purity appropriate for biochemical and cellular assays.
- Available in small research quantities for laboratory studies.
Medchemexpress LLC SEW2871 | 256414-75-2 | 99.9% | 440.36 | 10 MG
SEW2871 is an orally active, potent, highly selective S1P1 (sphingosine-1-phosphate type 1 receptor) agonist, with an EC50 of 13.8 nM. It activates ERK, Akt, and Rac signaling pathways and induces S1P1 internalization and recycling. SEW2871 reduces lymphocyte numbers in blood and can be used for the research of diabetes, Alzheimer's disease, liver fibrosis, and inflammatory responses.
- Orally active, potent, highly selective S1P1 agonist.
- Activates ERK, Akt, and Rac signaling pathways.
- Induces S1P1 internalization and recycling.
- Reduces lymphocyte numbers in blood.
- Can be used for research of diabetes, Alzheimer's disease, liver fibrosis, and inflammatory responses.
Medchemexpress LLC Chdi-390576 | 1629729-98-1 | 98.1% | 10 MG
A small-molecule, cell-permeable, CNS-penetrant class IIa histone deacetylase (HDAC) inhibitor for research use. It is suitable for biochemical and cellular assays to study HDAC biology and related pathways. Available as a solid and in ready-to-use DMSO solutions with recommended cold storage.
- Potent inhibition of class IIa HDAC isoforms (reported IC50s: HDAC4 54 nM, HDAC5 60 nM, HDAC7 31 nM, HDAC9 50 nM).
- High selectivity over class I and other HDAC isoforms (>500-fold vs class I; ~150-fold vs HDAC8 and HDAC6).
- High purity supply (approximately 98.1%).
- Supplied as powder and as 10 mM solutions in DMSO; recommended storage: powder -20°C, in solvent -80°C (short term at -20°C).
- Intended for research use only; not for human or diagnostic applications.
Medchemexpress LLC Nitrofurantoin | 67-20-9 | 238.16 | 5 G
Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. It acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections.
- Potent and orally active broad-spectrum beta-lactamase antimicrobial agent
- Acts as an antibiotic
- Used for the study of urinary tract infections (UTIs), including cystitis and kidney infections
- Targets bacteria
- Melting/freezing point of 268°C
Medchemexpress LLC Sincalide (ammonium) | 70706-98-8 | 99.2% | 1160.30 | 5 MG
Sincalide ammonium is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) used for intravenous applications like postevacuation cholecystography. It is a major bioactive segment of CCK, retaining most of its biological activities. It can promote gallbladder contraction and aids in diagnosing gallbladder and pancreas disorders.
- Increases bile secretion
- Causes gallbladder to contract and relax the sphincter of Oddi, facilitating bile drainage
- Shows inhibitory effect on myocardial fibrosis
- Plays a positive role in fighting inflammation, apoptosis, and collagen deposition
Medchemexpress LLC CCT365623 hydrochloride | 2126136-98-7 | 98.1% | 443.99 | C18H18ClNO4S3 | 25MG
CCT365623 hydrochloride is an orally active lysyl oxidase (LOX) inhibitor intended for preclinical research. It suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF, has an IC50 of 0.89 μM, and is reported to have good tolerability and pharmacokinetic properties.
- Orally active lysyl oxidase inhibitor.
- IC50 about 0.89 μM in biochemical assays.
- Suppresses EGFR and AKT phosphorylation driven by EGF.
- Reported good tolerability and pharmacokinetic properties in preclinical studies.
- High chemical purity suitable for research applications.
- Available as a 25 mg research package.
Selleck Chemical LLC Nitrofurantoin S4536-100mg
Nitrofurantoin (Macrodantin Furadantine Furadonine) is an antibiotic used to treat bladder infections It inhibits bacterial DNA RNA and cell wall protein synthesis
Medchemexpress LLC 1-aminohydantoin hydrochloride | 2827-56-7 | MFCD02181047 | >98.0% | 151.55 g/mol | C3H6ClN3O2 | 100mg
1-Aminohydantoin hydrochloride (Standard) is the analytical standard of 1-Aminohydantoin hydrochloride (HY-Y0469) This product is intended for research and analytical applications 1-Aminohydantoin hydrochloride is a major metabolite of Nitrofurantoin (HY-A0090) in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat milk et al 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of 1-Aminohydantoin hydrochloride before detection[1][2]
Medchemexpress LLC Trovafloxacin (mesylate) | 147059-75-4 | MFCD00913361 | 99.6% | 512.46 g·mol⁻¹ | C21H19F3N4O6S | 100 MG
Trovafloxacin mesylate is the methanesulfonate (mesylate) salt of trovafloxacin, a fluoroquinolone antibiotic used as a research tool compound and analytical reference in microbiological and biochemical studies.
- Fluoroquinolone antibiotic salt suitable for research and analytical applications.
- Broad-spectrum activity against Gram-positive, Gram-negative, and anaerobic bacteria.
- Molecular formula C21H19F3N4O6S and molecular weight 512.46 g·mol⁻¹.
- CAS number 147059-75-4 for precise identification.
- Soluble in DMSO; commonly supplied as a dry powder for laboratory use.
Medchemexpress LLC Etiocholanolone (5β-Androsterone) | 53-42-9 | 99.5% | 290.44 | 50 MG
Etiocholanolone (5β-Androsterone) is the excreted metabolite of testosterone and has anticonvulsant activity. Etiocholanolone is a less potent neurosteroid positive allosteric modulator (PAM) of the GABAA receptor than its enantiomer form.
- It is the excreted metabolite of testosterone.
- It has anticonvulsant activity.
- It is a less potent neurosteroid positive allosteric modulator of the GABAA receptor than its enantiomer form.
- It exhibits ED50 values of 57.6 and 109.1 mg/kg in the 6-Hz and PTZ tests, respectively.
Medchemexpress LLC Opiranserin hydrochloride | 1440796-75-7 | 99.6% | 430.97 | 10 MG
Opiranserin hydrochloride is a non-opioid and non-NSAID analgesic candidate. It functions as a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A). It also exhibits antagonistic activity on rP2X3. Opiranserin hydrochloride is being developed as an injectable agent for the treatment of postoperative pain.
- Functions as a dual antagonist of GlyT2 and 5HT2A.
- Exhibits antagonistic activity on rP2X3.
- Effectively reduces mechanical allodynia and pain-related behaviors.
- Involved in clinical trials for postoperative pain, healthy, and radiculopathy/sciatica.