Furans
Medchemexpress LLC MBCQ 50mg | 150450-53-6 | 50 MG
MBCQ is a selective cGMP-specific phosphodiesterase type 5 (PDE5) inhibitor supplied for research use. It exhibits potent PDE5 inhibition (IC50 19 nM) with minimal activity on other PDE isozymes, and is provided as a solid research reagent suitable for biochemical assays and in vivo studies.
- Potent PDE5 inhibition (IC50 19 nM).
- High selectivity versus other PDE isozymes (IC50 >100 μM).
- High purity suitable for research (99.8%).
- Soluble in DMSO at 100 mg/mL for in vitro applications.
- Stable as a powder at -20°C for long-term storage.
- Available in small pack sizes for laboratory use.
Medchemexpress LLC 2H-indol-2-one, 1,3-dihydro-3-(2-pyridinylmethylene)-(3Z)- | 187325-53-7 | 98.0% | 222.25 g/mol | C14H10N2O | 50MG
GSK-3β inhibitor 1 is a small-molecule inhibitor of glycogen synthase kinase-3 beta (CAS 187325-53-7) with low-nanomolar biochemical potency and reported antidiabetic efficacy in obese streptozotocin-treated rats. The compound is provided as a solid for research use and is soluble in DMSO with recommended storage conditions for powder and solutions.
Medchemexpress LLC Sonlicromanol | 1541170-75-5 | 99.8% | 50 MG
Sonlicromanol (KH176) is an orally active reactive oxygen species (ROS) modulator used in preclinical and clinical research to study mitochondrial disease. It is supplied for research use only and is typically provided as a small research pack for laboratory studies.
- Orally active small-molecule ROS modulator
- Modulates reductive and oxidative cellular distress with anti-inflammatory effects
- Used to investigate mitochondrial disease mechanisms and redox biology
- Shown to protect mitochondrial-diseased cells from redox stress in published studies
- Provided as a research reagent, not for therapeutic use
- Molecular formula C19H28N2O3, molecular weight 332.4 g/mol
Medchemexpress LLC Sonlicromanol | 1541170-75-5 | 99.8% | 10 MG
Sonlicromanol is an orally active reactive oxygen species (ROS) modulator used for mitochondrial disease research. It is provided as a high-purity research reagent with good solubility in DMSO.
- Orally active ROS modulator suitable for mitochondrial disease research.
- High purity, 99.75%.
- Molecular formula C19H28N2O3; molecular weight 332.44 g·mol⁻¹.
- Soluble in DMSO at approximately 25 mg/mL; sonication may be required.
- Packaged as 10 mg for laboratory research use.
TARGETMOL CHEMICALS INC Azimilide Dihydrochloride 25MG
Also available in 1 mL, 5 mg, 10 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the slowly activating (IKs) and rapidly activating (IKr) components of the delayed rectifier potassium current Purity 98%
Medchemexpress LLC CCT365623 hydrochloride | 2126136-98-7 | 98.1% | 443.99 | C18H18ClNO4S3 | 25MG
CCT365623 hydrochloride is an orally active lysyl oxidase (LOX) inhibitor intended for preclinical research. It suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF, has an IC50 of 0.89 μM, and is reported to have good tolerability and pharmacokinetic properties.
- Orally active lysyl oxidase inhibitor.
- IC50 about 0.89 μM in biochemical assays.
- Suppresses EGFR and AKT phosphorylation driven by EGF.
- Reported good tolerability and pharmacokinetic properties in preclinical studies.
- High chemical purity suitable for research applications.
- Available as a 25 mg research package.
![Medchemexpress LLC 2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide | 304896-28-4 | 99.6% | 434.27 | C23H13Cl2N3O2 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000211935.png-250.jpg)
Medchemexpress LLC 2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide | 304896-28-4 | 99.6% | 434.27 | C23H13Cl2N3O2 | 100 MG
AGK2 is a selective small-molecule inhibitor of SIRT2 used to probe sirtuin biology and apoptosis-related pathways in biochemical and cellular studies. It is cell permeable and reported to inhibit SIRT2 with an IC50 of 3.5 μM, while showing weaker activity against SIRT1 and SIRT3.
eMolecules Medchem Express / C646 / 10mg / 446263588 / HY-13823 / / 328968-36-1 / MFCD06125650 / 445.431 / C24H19N3O6
Medchem Express / C646 / 10mg / 446263588 / HY-13823 / / 328968-36-1 / MFCD06125650 / 445.431 / C24H19N3O6
Medchemexpress LLC CCT365623 hydrochloride | 2126136-98-7 | 98.1% | 443.99 g/mol | C18H18ClNO4S3 | 5MG
CCT365623 hydrochloride is the hydrochloride salt of a small-molecule lysyl oxidase (LOX) inhibitor used in preclinical research. It suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF, and has reported oral activity and favorable pharmacokinetic properties. The material is supplied as a solid and as a prepared DMSO solution for laboratory use and is intended for research use only.
Medchemexpress LLC ATH686 | 853299-52-2 | 99.5% | 515.53 | 50 MG
ATH686 is a potent, selective, and ATP-competitive FLT3 inhibitor. It targets mutant FLT3 protein kinase activity, inhibiting the proliferation of cells harboring FLT3 mutants by inducing apoptosis and cell cycle inhibition. It has demonstrated antileukemic effects.
- Potent, selective, and ATP-competitive FLT3 inhibitor.
- Targets mutant FLT3 protein kinase activity.
- Induces apoptosis and cell cycle inhibition.
- Inhibits proliferation of cells harboring FLT3 mutants.
- Demonstrates antileukemic effects.
- For research use only.
Apexbio Technology LLC Mometasone furoate 83919-23-7 50mg
Mometasone furoate (83919-23-7) is a glucocorticoid receptor agonist targeting intracellular glucocorticoid receptors It is designed to modulate glucocorticoid signaling pathways thereby regulating gene expression linked to inflammatory and allergic responses Mometasone furoate exerts its biological activity primarily through binding to cytoplasmic glucocorticoid receptors forming an activated complex that translocates into the nucleus and modulates target gene transcription This mechanism suppresses inflammatory cytokine production and inhibits inflammatory mediator release Based on these pharmacological properties Mometasone furoate holds research potential in experimental models of skin inflammatory disorders such as eczema and psoriasis as well as respiratory inflammatory processes including asthma
Cayman Chemical Mometason Furoate-d3 5mg
An internal standard for the quantification of mometasone furoate by GC- or LC-MS
eMolecules 2,3-Difluoro-4-ethoxybenzoic acid | 124728-45-6 | MFCD02258849 | 5g
Apollo Scientific | 2,3-Difluoro-4-ethoxybenzoic acid | 5g | 562456355 | PC7871 | 97.000 | 124728-45-6 | MFCD02258849 | 202.157 | C9H8F2O3
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC Sincalide (ammonium) | 70706-98-8 | 99.2% | 1160.30 | 5 MG
Sincalide ammonium is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) used for intravenous applications like postevacuation cholecystography. It is a major bioactive segment of CCK, retaining most of its biological activities. It can promote gallbladder contraction and aids in diagnosing gallbladder and pancreas disorders.
- Increases bile secretion
- Causes gallbladder to contract and relax the sphincter of Oddi, facilitating bile drainage
- Shows inhibitory effect on myocardial fibrosis
- Plays a positive role in fighting inflammation, apoptosis, and collagen deposition