Furans
Medchemexpress LLC Sincalide (ammonium) | 70706-98-8 | 99.2% | 1160.30 | 10 MG
Sincalide ammonium is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. It is a major bioactive segment of CCK that retains most of its biological activities. CCK-8 can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders, increasing bile secretion, causing gallbladder contraction, and relaxing the sphincter of Oddi for bile drainage into the duodenum.
- Significant inhibitory effect on myocardial fibrosis in noninfarcted areas
- Positive role in fighting inflammation, apoptosis, and collagen deposition
- Protects H9c2 cardiomyoblasts from Ang II‐induced apoptosis
- Alleviates fibrosis in noninfarcted regions
- Delays left ventricular remodeling and the progress of heart failure in a MI rat model
Medchemexpress LLC CCT365623 hydrochloride | 2126136-98-7 | 98.1% | 443.99 | C18H18ClNO4S3 | 100MG
CCT365623 hydrochloride is a research-grade small molecule lysyl oxidase (LOX) inhibitor used in biochemical and cellular studies. It is supplied as a solid (white to yellow) with reported potency IC50 0.89 μM against LOX. Analytical purity is 98.07%, molecular weight 443.99, and formula C18H18ClNO4S3. The compound is highly soluble in DMSO (250 mg/mL) and is hygroscopic in solution; store sealed and away from moisture, with solvent storage recommended at -80°C (up to 6 months) or -20°C (up to 1 month).
- Potent LOX inhibition with reported IC50 0.89 μM.
- High analytical purity of 98.07%.
- Molecular weight 443.99.
- Chemical formula C18H18ClNO4S3.
- Soluble in DMSO at 250 mg/mL; ultrasonic aid may be required.
- Solid, white to yellow; hygroscopic in DMSO.
- Store sealed away from moisture; solvent storage -80°C (6 months).
Medchemexpress LLC Lobenzarit | 63329-53-3 | MFCD00866065 | 99.4% | 291.69 | C14H10ClNO4 | 10MG
Lobenzarit is a small-molecule immunomodulator provided for laboratory research. It exhibits antioxidative activity and is intended for use in in vitro and preclinical studies; consult the supplier COA and SDS for handling, storage, and purity information.
- Immunomodulatory activity
- Antioxidative properties
- High purity: 99.4%
- Available in small mass quantities suitable for research
- Documentation provided: COA and SDS
- Intended for in vitro and preclinical applications
Medchemexpress LLC 2,4-imidazolidinedione, 1-amino-, hydrochloride (1:1) | 2827-56-7 | MFCD02181047 | 98.0% | 151.55 | C3H6ClN3O2 | 10g
1-Aminohydantoin hydrochloride is a major metabolite of Nitrofurantoin (HY-A0090) in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat milk et al 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of 1-Aminohydantoin hydrochloride before detection[1][2]
Medchemexpress LLC Cobomarsen | 1848257-52-2 | C148H177N52O77P13S13 | 10MG
Cobomarsen is a locked nucleic acid (LNA)-based antisense oligonucleotide that selectively inhibits microRNA-155 (miR-155). Supplied as a solid (white to off-white) research reagent, it is used in preclinical studies to modulate miR-155-driven signaling and investigate oncology models by affecting pathways such as JAK/STAT, MAPK/ERK, and PI3K/AKT. The sodium salt form offers improved stability; the compound is highly water soluble and requires sealed, moisture-free storage.
- Selective inhibition of miR-155 and related survival pathways
- Suitable for preclinical oncology and lymphoma research
- High aqueous solubility; may require ultrasonication
- Improved stability as the sodium salt compared with the free acid
- Store sealed and protected from moisture; long-term storage in solution at -80 °C
Medchemexpress LLC Etiocholanolone (5β-Androsterone) | 53-42-9 | 99.5% | 290.44 | 50 MG
Etiocholanolone (5β-Androsterone) is the excreted metabolite of testosterone and has anticonvulsant activity. Etiocholanolone is a less potent neurosteroid positive allosteric modulator (PAM) of the GABAA receptor than its enantiomer form.
- It is the excreted metabolite of testosterone.
- It has anticonvulsant activity.
- It is a less potent neurosteroid positive allosteric modulator of the GABAA receptor than its enantiomer form.
- It exhibits ED50 values of 57.6 and 109.1 mg/kg in the 6-Hz and PTZ tests, respectively.
Medchemexpress LLC Nitrofurantoin | 67-20-9 | 238.16 | 5 G
Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. It acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections.
- Potent and orally active broad-spectrum beta-lactamase antimicrobial agent
- Acts as an antibiotic
- Used for the study of urinary tract infections (UTIs), including cystitis and kidney infections
- Targets bacteria
- Melting/freezing point of 268°C
Medchemexpress LLC SID7970631 | 868224-75-3 | 98.30% | 10 MG
SID7970631 is an isoquinolinone analog that functions as a potent and selective submicromolar SF-1 inhibitor (IC50=255 nM). It can be used for cancer research.
- Potent and selective submicromolar SF-1 inhibitor
- IC50 of 255 nM (SF-1)
- Displays cytotoxic effects on H295R/TR SF-1 cells and SW-13 cells
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Galicaftor | 1918143-53-9 | 98.6% | 559.46 g/mol | C28H21F4NO7 | 5 MG
Galicaftor is a small-molecule, orally active CFTR corrector used in cystic fibrosis research. It is provided for laboratory research use only and is available as a solid and as DMSO solutions; analytical data and storage recommendations are supplied by the manufacturer.
- Potent CFTR corrector activity suitable for preclinical studies.
- High purity for reliable analytical and biological assays.
- Available as solid packs and ready-to-use DMSO solutions.
- Defined storage conditions to maintain stability.
- Chemical identification data (CAS, formula, molecular weight) provided.
Medchemexpress LLC HY-19726 5mg Medchemexpress, NSC59984 CAS:803647-40-7 Purity:>98%
Medchemexpress, HY-19726 5mg NSC59984 CAS:803647-40-7 NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway. NSC59984 acts by targeting GOF-mutant p53 and stimulates p73 to restore the p53 pathway signaling. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Pyribencarb | 799247-52-2 | MFCD22200855 | ≥95.0% | 361.83 | C18H20ClN3O3 | 50 MG
Pyribencarb is a benzylcarbamate-class fungicide supplied as a research-grade standard. It acts as a Qo inhibitor of cytochrome b (complex III) in the mitochondrial electron transport chain and shows activity against a broad range of plant pathogenic fungi. The compound is intended for analytical, in vitro antifungal, and mode-of-action studies.
- Inhibits cytochrome b (complex III) via the Qo site, enabling mechanism-of-action research.
- Active against common plant pathogens such as Botrytis cinerea and Sclerotinia sclerotiorum.
- Provided as a solid reference material suitable for analytical assays and standards.
- Storage stability as powder at low temperatures supports long-term archiving.
- Applicable to in vitro antifungal testing and comparative potency studies.
Aobchem 6-[(Tetrahydro-3-furanyl)oxy]-3-pyridinecarboxaldehyde | 95% | CAS 2293404-57-4 | C10H11NO3 | 500mg
6-[(Tetrahydro-3-furanyl)oxy]-3-pyridinecarboxaldehyde | 95% | CAS 2293404-57-4 | C10H11NO3 | 500mg
Medchemexpress LLC Tovinontrine (IMR-687) | 2062661-53-2 | 99.8% | 394.47 | 1 ML
Tovinontrine (IMR-687) | 2062661-53-2 | 99.8% | 394.47 | 1 ML