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Filtered Search Results
Medchemexpress LLC 2,4-dihydro-5-(4-nitrophenyl)-2-phenyl-3H-pyrazol-3-one | 34320-83-7 | MFCD00506084 | 99.7% | 281.27 | C15H11N3O3 | 10 MG
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TCS PrP Inhibitor 13 is a small-molecule antiprion agent that inhibits cellular prion protein (PrPC) and reduces protease-resistant prion accumulation. It is supplied as a solid for research use and shows potent activity in cellular assays (IC50 3 nM).
- Chemical formula: C15H11N3O3.
- Molecular weight: 281.27.
- Purity: 99.7%.
- Appearance: solid, white to yellow.
- Storage conditions: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Reported activity: IC50 3 nM in ScN2a and F3 cells.
- Biological effect: induces apoptosis in schwannoma cells.
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Medchemexpress LLC (E)-4-(2-chloro-6-fluorostyryl)-N-methylaniline | 1391934-98-7 | 98.5% | C15H13ClFN | 10MG
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FIDAS-5 is a small-molecule research compound that inhibits methionine S-adenosyltransferase 2A (MAT2A). It competitively displaces S-adenosylmethionine with a reported IC50 of 2.1 μM and has demonstrated anticancer activity in preclinical studies. The material is supplied as a high-purity solid powder for laboratory research and is unstable in solution, so fresh preparations are recommended.
- Potent MAT2A inhibitor with IC50 = 2.1 μM.
- High purity (≈98.5%).
- Molecular formula C15H13ClFN; molecular weight 261.72.
- Supplied as a solid; available in small pack sizes including 10 mg.
- Powder stable at -20°C; unstable in solution, prepare fresh solutions.
- Used in preclinical and in vitro anticancer research.
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Medchemexpress LLC 2-[(2-carboxyphenyl)amino]-4-chlorobenzoic acid | 63329-53-3 | MFCD00866065 | 99.4% | 291.68 g/mol | C14H10ClNO4 | 50MG
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Lobenzarit is a small-molecule immunomodulator used in preclinical research that has reported anti-oxidative and anti-inflammatory properties. It is supplied as a high-purity research reagent (CAS 63329-53-3) and is used in vitro and in vivo to study immune modulation and anti-arthritic effects.
- High purity suitable for research use.
- Reported immunomodulatory and anti-oxidative activity.
- Available in multiple small-scale sizes for preclinical studies.
- Stable when stored under recommended conditions (powder and in solvent).
- Molecular formula C14H10ClNO4; molecular weight 291.68 g/mol.
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Medchemexpress LLC 3-Pyridinecarboxamide, 6-fluoro-N-[2-fluoro-3-[[[2-iodo-4-[1,2,2,2-tetrafluoro-1-(trifluorometh | 1331922-53-2 | 98.3% | 715.23 | 50 MG
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Modoflaner is an isophenylamide insecticide intended for research use only. It may act through allosteric regulation of gamma-aminobutyric acid-gated chloride channels.
- Isophenylamide insecticide
- May act through allosteric regulation of gamma-aminobutyric acid-gated chloride channels
- Effectively kills moth, xylophone, and gray planthopper
- Prevents female adult ticks from laying eggs or eggs from hatching
- White to off-white solid appearance
- Purity of 98.26%
- Store at 4°C, protected from light; in solvent at -80°C for 6 months or -20°C for 1 month, protected from light
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Alkali Scientific Nitrofurantoin, 100 Grams
Nitrofurantoin, 100g is a laboratory-grade antibacterial agent commonly used for research in microbiology and pharmacology. Nitrofurantoin is effective against a wide range of Gram-positive and Gram-negative bacteria, particularly in urinary tract infections. The formulation provides a convenient bulk quantity, making it suitable for large-scale research studies or ongoing laboratory investigations. Researchers use nitrofurantoin to study its antimicrobial properties, resistance mechanisms, and its effectiveness in clinical settings. This product is designed for laboratory applications and is not intended for human consumption, ensuring that it meets the standards required for scientific and educational use in laboratory experiments.
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Medchemexpress LLC Calceolarioside B | 105471-98-5 | 478.45 | 5 MG
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Calceolarioside B is a phenylethanoid glycoside that can be isolated from the leaves of Akebia quinata. It inhibits RLAR activity with an IC50 value of 23.99 μM, inhibits the entry of the Omicron BA.2 pseudovirus into host cells, and reduces IL-6 levels. Calceolarioside B also possesses immunomodulatory and anticancer activities against human hormone-independent prostate cancer.
- Inhibits RLAR activity.
- Inhibits entry of Omicron BA.2 pseudovirus into host cells.
- Reduces IL-6 levels.
- Possesses immunomodulatory activity.
- Exhibits anticancer activity against human hormone-independent prostate cancer.
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Medchemexpress LLC JQKD82 trihydrochloride | 2863676-87-1 | MFCD34676876 | 99.9% | 610.01 g/mol | C27H43Cl3N4O5 | 5 MG
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JQKD82 trihydrochloride is the trihydrochloride salt of a selective, cell-permeable small-molecule inhibitor of KDM5 histone demethylases. It elevates H3K4me3 levels in cells and is used in cellular and epigenetic studies, including multiple myeloma research. Molecular formula C27H43Cl3N4O5; molecular weight 610.01 g/mol; reported purity 99.89%.
- Selective KDM5 inhibitor suitable for cellular assays.
- Increases H3K4me3 levels in treated cells.
- Cell-permeable small-molecule salt form.
- High reported purity of 99.89%.
- Supplied as solid and as DMSO stock solutions.
- Useful for epigenetic and cancer research applications.
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Medchemexpress LLC Nitrofurantoin-13c3 | 1217226-46-4 | C₅¹³C₃H₆N₄O₅ | 1 MG
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Nitrofurantoin-13C3 is the 13C labeled Nitrofurantoin. Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. It acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes (carbon) for quantitation during drug development.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
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Medchemexpress LLC YH-306 | 1373764-75-0 | 98.3% | 5 MG
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YH-306 is a small-molecule antitumor agent that inhibits focal adhesion kinase (FAK) signaling and reduces cancer cell migration, invasion, and metastasis in preclinical studies.
- Inhibits focal adhesion kinase (FAK) signaling and related pathways.
- Reduces expression of MMP2 and MMP9.
- Inhibits Arp2/3-mediated actin polymerization.
- Molecular formula: C19H18N2O2.
- Molecular weight: 306.36 g/mol.
- Purity: 98.3%.
- Appearance: light yellow to light brown solid.
- Storage: 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month).
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Medchemexpress LLC L-Anserine nitrate | 10030-52-1 | CB6371678 | 99.65% | 303.28 | 10 MG
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L-Anserine nitrate is an endogenous metabolite. It is intended for research use only, and MedChemExpress does not sell to patients.
- Endogenous metabolite
- For research use only
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Medchemexpress LLC JNJ-55308942 | 2166558-11-6 | 99.9% | 425.32 | C17H12F5N7O | 5MG
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JNJ-55308942 is a selective, brain-penetrant P2X7 receptor antagonist supplied for research use. It shows high affinity for human and rat P2X7 channels and includes solubility and formulation guidance to support both in vitro and in vivo studies.
- Selective P2X7 antagonist with hP2X7 IC50 = 10 nM and rP2X7 IC50 = 15 nM.
- Brain-penetrant, suitable for central nervous system studies.
- Molecular formula C17H12F5N7O; molecular weight 425.32.
- High purity (≈99.9%).
- Soluble in DMSO (100 mg/mL); in vivo formulations ≥4 mg/mL reported.
- Supplied in small milligram pack sizes for research applications.
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Apexbio Technology LLC Terlipressin diacetate 1884420-36-3 25mg
Terlipressin diacetate (CAS 1884420-36-3) is a synthetic analogue of vasopressin classified as a vasopressin receptor agonist It exhibits high selectivity for V1 receptors localized on vascular smooth muscle where it induces pronounced vasoconstriction by activating the phospholipase C inositol 1 4 5-trisphosphate (IP3) signaling pathway This leads to increased vascular resistance and elevated blood pressure Terlipressin diacetate is widely utilized in biomedical research investigating mechanisms of vascular tone regulation hemodynamic response in portal hypertension and pathophysiology of conditions such as variceal bleeding and hepatorenal syndrome
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eMolecules 1260667-24-0 | 3-ETHYNYLTETRAHYDRO-2H-PYRAN | AstaTech | MFCD18250569 | 110.156 | C7H10O | 95.000 | C#CC1CCCOC1 | 1g | 391060138
3-ETHYNYLTETRAHYDRO-2H-PYRAN | AstaTech | 1260667-24-0 | MFCD18250569 | 110.156 | C7H10O | 95.000 | C#CC1CCCOC1 | 1g | 391060138
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Medchemexpress LLC 4-[2-(cyclopropylmethoxy)-5-(methylsulfonyl)phenyl]-2-methyl-1(2H)-isoquinolinone | 1706738-98-8 | >98.0% | C21H21NO4S | 10MG
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Trotabresib is an oral, potent, reversible small-molecule inhibitor of bromodomain and extra-terminal (BET) proteins. It is used in preclinical and clinical oncology research for advanced solid tumors and glioma and is supplied as a research-grade solid for translational studies.
- Oral, reversible BET inhibitor suitable for epigenetic research.
- Demonstrates antitumor activity in cell lines and xenograft models.
- High purity (typically >98%) for reliable experimental results.
- Solid powder form, soluble in common organic solvents such as DMSO.
- Applicable to preclinical and clinical translational studies in oncology.
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Medchemexpress LLC 7-TFA-ap-7-Deaza-dA | 178420-75-2 | 98.8% | 399.32 | 100 MG
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7-TFA-ap-7-Deaza-dA is a modified nucleoside and a click chemistry reagent. It is utilized in the synthesis of deoxyribonucleic acid or nucleic acid. Featuring an alkyne group, this compound is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. It is intended for laboratory use and substance manufacturing, strictly for research purposes.
- Modified nucleoside
- Click chemistry reagent
- Contains an alkyne group for CuAAc reactions
- Supports DNA and nucleic acid synthesis
- For laboratory chemicals and substance manufacturing
- For research use only
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