Lactams
Medchemexpress LLC Thalidomide-piperazine 5-fluoride hydrochloride | 2222114-23-8 | MFCD32203462 | 98.9% | 396.80 g/mol | C17H18ClFN4O4 | 5 G
Thalidomide-piperazine 5-fluoride hydrochloride is a thalidomide-derived cereblon (CRBN) E3 ubiquitin ligase ligand supplied as the hydrochloride salt for research use. It is a light-yellow solid with high reported purity and is intended for use in PROTAC synthesis and related chemical biology applications.
- Used as a ligand for cereblon (CRBN) in PROTAC synthesis.
- High purity (98.9%) suitable for research applications.
- Provided as a hydrochloride salt for improved handling.
- Light yellow solid form for easy weighing and storage.
- Storage: room temperature; in solvent, -80°C (2 years) or -20°C (1 year).
- Available in multiple package sizes including gram-scale quantities.
Apexbio Technology LLC Sulbactam sodium 69388-84-7 10mM (in 1mL H2O)
Sulbactam sodium is a competitive and irreversible inhibitor targeting -lactamase enzymes It functions predominantly through binding the active site of -lactamases thereby obstructing these enzymes from hydrolyzing -lactam antibiotics Widely employed in biomedical research Sulbactam sodium is utilized for evaluating bacterial resistance mechanisms characterizing susceptibility profiles of -lactamase-expressing clinical isolates and examining synergistic therapeutic combinations Moreover Sulbactam sodium itself exhibits antimicrobial activity notably against Acinetobacter species clinically resistant to common antibiotics In antibacterial assays against certain -lactamase-producing bacterial strains Sulbactam sodium typically demonstrates inhibitory effects at IC50 values ranging approximately from 5 to 25 g/mL depending upon specific experimental conditions
Medchemexpress LLC Sulbactam | 68373-14-8 | 100.0% | 1 ML
Sulbactam is a competitive, irreversible beta-lactamase inhibitor that demonstrates antimicrobial activity against multidrug-resistant (MDR) Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex. It exhibits a wide range of antibacterial activity against both Gram-positive and Gram-negative aerobic and anaerobic bacteria.
- Competitive, irreversible beta-lactamase inhibitor
- Antimicrobial against multidrug-resistant Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex
- Wide range of antibacterial activity
- Active against Gram-positive and Gram-negative aerobic and anaerobic bacteria
- For research use only
Medchemexpress LLC Thalidomide-O-C6-COOH | 2169266-69-5 | 99.29% | 50 MG
Thalidomide-O-C6-COOH is a synthesized E3 ligase ligand-linker conjugate. It incorporates a Thalidomide-based cereblon ligand and a linker, which is used in PROTAC (Proteolysis-Targeting Chimera) technology. This compound is intended for research use only.
- Utilizes the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Composed of two different ligands connected by a linker
Medchemexpress LLC Fc epsilon RIA/FCER1A protein, mouse (HEK293, C-hFc) | >85.0% | 5 UG
Recombinant mouse Fc epsilon RI alpha (FCER1A) extracellular domain fused to a C-terminal human Fc, expressed in HEK293 cells and supplied lyophilized. Intended for immunoassays, binding studies, and functional assays involving IgE-FcεRI interactions; documentation including datasheet and COA is available.
Medchemexpress LLC Tazobactam | 89786-04-9 | 99.9% | 1 ML
Tazobactam is a potent β-lactamases inhibitor and penicillin antibiotic. It exhibits antibacterial activity and can be used for pneumonia research.
- Potent β-lactamases inhibitor
- Penicillin antibiotic
- Antibacterial activity
- Can be used for pneumonia research
Medchemexpress LLC Tazobactam | 89786-04-9 | 5 G
Tazobactam (CL-298741) is a potent β-lactamases inhibitor and a penicillin antibiotic. It exhibits antibacterial activity and can be used for pneumonia research. This product is intended for research and analytical applications.
- Potent β-lactamases inhibitor
- Penicillin antibiotic
- Exhibits antibacterial activity
- Can be used for pneumonia research
- Intended for research and analytical applications
Medchemexpress LLC Thalidomide-pyrrolidine hydrochloride | 2616553-35-4 | 98.0% | 335.74 | C15H14ClN3O4 | 5 MG
Thalidomide-pyrrolidine hydrochloride is a cereblon-binding E3 ligase ligand supplied as the hydrochloride salt for use as a building block in PROTAC synthesis and targeted protein degradation research. It is intended for research use and is accompanied by quality documentation.
- Cereblon-binding E3 ligase ligand for PROTAC synthesis.
- Hydrochloride salt form for handling and stability.
- High purity: 98.0%.
- Documented quality: data sheet, certificate of analysis, and safety data sheet available.
- Storage recommendations: store dry at room temperature; in solvent, -80°C (2 years) or -20°C (1 year).
Medchemexpress LLC Thalidomide-4-O-CH2-COO(t-Bu) | 1950635-36-5 | MFCD32643096 | 99.3% | 388.37 | C19H20N2O7 | 10 MG
Thalidomide-4-O-CH2-COO(t-Bu) is a tert-butyl protected thalidomide derivative used as a cereblon (CRBN) binding ligand and as a synthetic intermediate in the preparation of PROTAC molecules. It is supplied for research use only and is not intended for human use.
- Tert-butyl protected thalidomide derivative suitable for deprotection under acidic conditions.
- Functions as a cereblon (CRBN) binding ligand for use in PROTAC design.
- High reported purity (~99.3%) for reliable research applications.
- Available in small research pack sizes (mg scale) for synthetic workflows.
- Stable at room temperature for extended storage; follow solvent storage recommendations for longer-term stability.
Medchemexpress LLC Thalidomide-piperazine-PEG2-COOH | 2797430-20-5 | 99.8% | C24H30N4O8 | 10MG
Thalidomide-Piperazine-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that pairs a thalidomide-derived cereblon ligand with a PEG2-containing piperazine linker. It is intended for use in proteolysis-targeting chimera (PROTAC) research and supports conjugation via a terminal carboxylic acid for downstream coupling.
- High purity suitable for research applications.
- Contains a carboxylic acid functional group for facile coupling.
- Designed to recruit the cereblon E3 ligase in degrader constructs.
- PEG2 linker provides short, flexible spacer for conjugation.
- Characterized by molecular formula C24H30N4O8 and molecular weight 502.52 g·mol⁻¹.
Medchemexpress LLC Thalidomide-NH-C4-NH-Boc | 2093388-52-2 | 99.6% | 50 MG
Thalidomide-NH-C4-NH-Boc is a synthesized E3 ligase ligand-linker conjugate. It incorporates a Thalidomide based cereblon ligand and a linker, used in PROTAC technology. This product is for research use only.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates Thalidomide based cereblon ligand
- Used in PROTAC technology
- Targets cereblon
- Solid appearance
- Color: yellow to green
- For research use only
Medchemexpress LLC Thalidomide-C2-amido-C2-COOH | 2353496-84-9 | 98.5% | 416.38 g/mol | C19H20N4O7 | 5 MG
Thalidomide-C2-amido-C2-COOH is an E3 ligase ligand-linker conjugate that incorporates a cereblon-binding thalidomide-derived moiety and a carboxylic acid linker. It is intended for use as a research reagent in PROTAC design and related chemical biology studies; not for human or clinical use.
- CAS number: 2353496-84-9.
- Molecular formula: C19H20N4O7.
- Molecular weight: 416.38 g/mol.
- Purity: 98.45% (typical by supplier).
- Solubility: DMSO up to 100 mg/mL (may require sonication).
- Storage: powder at -20°C; stock solutions at -80°C for long term.
- Intended use: CRBN ligand for PROTAC design and E3 ligase studies.
- Available in small mg quantities for research use.
eMolecules Synthonix 4-Acetoxy-2-azetidinone 250mg 779536178 A15221 0 000 28562-53-0 MFCD00010593 129 115 C5H7NO3
Synthonix 4-Acetoxy-2-azetidinone 250mg 779536178 A15221 0 000 28562-53-0 MFCD00010593 129 115 C5H7NO3