Pyridines and derivatives
- (4)
- (1)
- (5)
- (5)
- (597)
- (22)
- (2,186)
- (22)
- (2)
- (5)
- (5)
- (309)
- (181)
- (1)
- (14)
- (51)
- (2)
- (303)
- (87)
- (245)
- (6)
- (4)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (5)
- (1)
- (12)
- (4)
- (8)
- (7)
- (12)
- (60)
- (875)
- (6)
- (56)
- (66)
- (58)
- (19)
- (357)
- (2)
- (4)
- (2)
- (1)
- (1)
- (5)
- (303)
- (1)
- (1,713)
- (2)
- (29)
- (7)
- (1)
- (92)
- (4)
- (15)
- (86)
- (128)
- (55)
- (60)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (5)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (3)
- (3)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (9)
- (4)
- (1)
- (2)
- (4)
- (2)
- (1)
- (6)
- (17)
- (23)
- (1)
- (1)
- (63)
- (21)
- (1)
- (1)
- (29)
- (50)
- (7)
- (2)
- (1)
- (5)
- (6)
- (12)
- (1)
- (1)
- (1)
- (1)
- (18)
- (1)
- (14)
- (4)
- (1)
- (11)
- (5)
- (1)
- (10)
- (17)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (9)
- (7)
- (1)
- (2)
- (1)
- (4)
- (6)
- (2)
- (1)
- (1)
- (1)
- (4)
- (4)
- (1)
- (1)
- (5)
- (15)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (12)
- (1)
- (2)
- (1)
- (2)
- (4)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (15)
- (18)
- (4)
- (2)
- (2)
- (5)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (7)
- (5)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (16)
- (7)
- (5)
- (1)
- (1)
- (3)
- (5)
- (10)
- (2)
- (1)
- (6)
- (6)
- (7)
- (12)
- (1)
- (1)
- (39)
- (1)
- (12)
- (11)
- (4)
- (2)
- (2)
- (15)
- (15)
- (1)
- (1)
- (1)
- (2)
- (9)
- (3)
- (2)
- (1)
- (1)
- (1)
- (4)
- (6)
- (3)
- (3)
- (1)
- (4)
- (1)
- (1)
- (1)
- (3)
- (3)
- (1)
- (6)
- (5)
- (2)
- (1)
- (19)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (22)
- (24)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (22)
- (16)
- (6)
- (2)
- (1)
- (1)
- (3)
- (7)
- (1)
- (2)
- (3)
- (1)
- (1)
- (2)
- (1)
- (8)
- (17)
- (3)
- (1)
- (8)
- (1)
- (3)
- (1)
- (2)
- (1)
- (6)
- (3)
- (4)
- (2)
- (1)
- (1)
- (1)
- (6)
- (3)
- (3)
- (3)
- (3)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (6)
- (1)
- (1)
- (2)
- (5)
- (3)
- (1)
- (4)
- (12)
- (49)
- (1)
- (4)
- (2)
- (3)
- (1)
- (2)
- (1)
- (1)
- (7)
- (10)
- (22)
- (30)
- (1)
- (1)
- (1)
- (3)
- (2)
- (2)
- (4)
- (11)
- (5)
- (1)
- (1)
- (55)
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- (1)
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- (1)
- (1)
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- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (35)
- (3)
- (4)
- (4)
- (3)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (5)
- (3)
- (5)
- (8)
- (4)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (4)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (10)
- (2)
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- (1)
- (13)
- (2)
- (3)
- (1)
- (1)
- (5)
- (19)
- (1)
- (13)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (18)
- (11)
- (18)
- (1)
- (2)
- (3)
- (1)
- (17)
- (8)
- (6)
- (2)
- (3)
- (2)
- (2)
- (1)
- (4)
- (4)
- (1)
- (3)
- (2)
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- (11)
- (2)
- (2)
- (2)
- (4)
- (1)
- (8)
- (5)
- (6)
- (24)
- (3)
- (1)
- (2)
- (6)
- (1)
- (4)
- (1)
- (1)
- (2)
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- (1)
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- (1)
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- (26)
- (8)
- (1)
- (1)
- (1)
- (7)
- (9)
- (1)
- (1)
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- (1)
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- (1)
- (1)
- (3)
- (2)
- (1)
- (2)
- (2)
- (1)
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- (1)
- (6)
- (28)
- (2)
- (15)
- (4)
- (3)
- (9)
- (4)
- (4)
- (18)
- (8)
- (2)
- (4)
- (7)
- (2)
- (33)
- (2)
- (75)
- (1)
- (4)
- (53)
- (1)
- (3)
- (1)
- (10)
- (6)
- (33)
- (1)
- (6)
- (1)
- (1)
- (106)
- (1)
- (11)
- (544)
- (5)
- (462)
- (42)
- (22)
- (130)
- (9)
- (2)
- (117)
- (1)
- (2)
- (3)
- (1)
- (1)
- (28)
- (32)
- (15)
- (4)
- (13)
- (12)
- (2)
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- (2)
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- (1)
- (3)
- (2)
- (1)
- (1)
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- (20)
- (1)
- (1)
- (1)
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- (1)
- (1)
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- (4)
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- (27)
- (3)
- (1)
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- (1)
- (50)
- (1)
- (11)
- (373)
- (5)
- (3)
- (138)
- (1)
- (1,048)
- (4)
- (2)
- (1)
- (2)
- (3)
- (12)
- (924)
- (7)
- (35)
- (7)
- (2)
- (1)
- (501)
- (26)
- (1)
- (1)
- (4)
- (18)
- (1)
- (1)
- (1)
- (4)
- (4)
- (1)
- (2)
- (6)
- (4)
- (4)
- (1)
- (1)
- (4)
- (1)
- (3)
- (19)
- (2)
- (8)
- (72)
- (4)
- (1,561)
- (2)
- (4)
- (12)
- (9)
- (1)
- (14)
- (3)
- (9)
- (3)
- (2)
- (5)
- (4)
- (2)
- (1)
- (16)
- (3)
- (13)
- (11)
- (13)
- (10)
- (2)
- (2)
- (1)
- (2)
- (2)
- (408)
- (5)
- (6)
- (2)
- (7)
- (2)
- (3)
- (2)
- (237)
- (3)
- (2)
- (3)
- (18)
- (5)
- (2)
- (264)
- (3)
- (4)
- (4)
- (1)
- (2)
- (1)
- (4)
- (1)
- (2)
- (2)
- (2)
- (5)
- (2)
- (3)
- (9)
- (3)
- (2)
- (2)
- (2)
- (2)
- (7)
- (1)
- (1)
- (1)
- (2)
- (2)
- (8)
- (3)
- (2)
- (2)
- (5)
- (4)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
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- (3)
- (1)
- (2)
- (3)
- (13)
- (1)
- (2)
- (1)
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- (2)
- (1)
- (1)
- (1)
- (1)
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- (1)
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- (1)
- (1)
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- (1)
- (1)
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- (1)
- (2)
- (1)
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- (3)
- (1)
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- (1)
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- (1)
- (1)
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- (1)
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- (1)
- (4)
- (2)
- (2)
- (5)
- (1)
- (2)
- (4)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
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- (1)
- (2)
- (3)
- (3)
- (4)
- (2)
- (1)
- (3)
- (3)
- (2)
- (3)
- (1)
- (1)
- (5)
- (1)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
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- (1)
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- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (1)
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- (1)
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- (1)
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- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (3)
- (6)
- (1)
- (4)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (2)
- (3)
- (1)
- (4)
- (3)
- (6)
- (1)
- (3)
- (1)
- (9)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (6)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (3)
- (3)
- (1)
- (1)
- (2)
- (1)
- (3)
- (2)
- (2)
- (2)
- (1)
- (2)
- (6)
- (1)
- (2)
- (1)
- (1)
- (3)
- (9)
- (2)
- (1)
- (1)
- (2)
- (1)
- (3)
- (1)
- (2)
- (1)
- (3)
- (3)
- (2)
- (6)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
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- (3)
- (2)
- (2)
- (1)
- (1)
- (1)
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- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (2)
- (2)
- (2)
- (1)
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- (1)
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- (1)
- (3)
- (2)
- (3)
- (9)
- (4)
- (1)
- (4)
- (4)
- (1)
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- (1)
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Filtered Search Results
Medchemexpress LLC Ki-tox-a3 | 1351116-34-1 | >99.15% | 319.31 | 25 MG
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KI-TOX-A3 is a selective protein-protein interaction (PPI) inhibitor targeting the TOX protein, with an IC50 value of 0.51 μM for TOX-KAT7 interaction. It induces proteasomal degradation of TOX, which restores KAT7-mediated H3K14 acetylation. This action reverses CD8+ T cell exhaustion and inhibits the proliferation of T-cell acute lymphoblastic leukemia (T-ALL) cells. KI-TOX-A3 shows promise for research in hematological tumors such as T-ALL.
- Selective PPI inhibitor targeting TOX protein
- Induces proteasomal degradation of TOX
- Restores KAT7-mediated H3K14 acetylation
- Reverses CD8+ T cell exhaustion
- Inhibits T-cell acute lymphoblastic leukemia (T-ALL) cell proliferation
- Promising for research of hematological tumors
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Cambridge Isotope Laboratories Comprehensive PCB Calibration Solution (CS2) 0 2 mL
Comprehensive PCB Calibration Solution (CS2) 0 2 mL
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![Medchemexpress LLC 1H-Benzimidazole-2-methanamine, N-[[3-ethoxy-4-(2-thienylmethoxy)phenyl]methyl]- | 878949-21-4 | 99.31% | 393.50 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000386461-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1H-Benzimidazole-2-methanamine, N-[[3-ethoxy-4-(2-thienylmethoxy)phenyl]methyl]- | 878949-21-4 | 99.31% | 393.50 | 5 MG
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DCEM1 binds to heat shock protein 60 (HSP60) and inhibits its interaction with ClpP, which blocks the mitochondrial unfolded protein response. It also inhibits β-catenin expression and ATP production in PC-3 and TKO cells. DCEM1 can be used in prostate cancer research.
- Binds to heat shock protein 60 (HSP60)
- Inhibits the interaction of HSP60 with ClpP
- Blocks the mitochondrial unfolded protein response
- Inhibits β-catenin expression
- Inhibits ATP production in PC-3 and TKO cells
- Can be used in prostate cancer research
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Medchemexpress LLC Antennapedia peptide (penetratin peptide) | 188842-14-0 | 98.4% | 2246.73 | 5 MG
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Antennapedia peptide (Penetratin peptide) is a 16 amino acid peptide derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia. As a member of the cell-penetrating peptides family, it activates caspase-dependent apoptosis and has been shown to have radiation-sensitising effects on tumor cells.
- Derived from Drosophila transcription factor Antennapedia
- 16 amino acid peptide
- Member of cell-penetrating peptides family
- Activates caspase-dependent apoptosis
- Has radiation-sensitising effects
- Increases levels of cleaved caspase-3
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BIOHIPPO Anti-IARS1 Polyclonal Antibody, 100 µg
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Human IARS1 Polyclonal Antibody is a Rabbit-derived polyclonal antibody that specifically recognizes IARS1. It shows reactivity with Human, Mouse, Rat. Validated applications include ELISA, IHC, WB. Purified by antigen affinity column. Supplied as 100 ug.
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Medchemexpress LLC Alpha-MCPG | 146669-29-6 | MFCD00210205 | 99.1% | 209.20 g·mol⁻¹ | C10H11NO4 | 50 MG
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Alpha-MCPG is a research-grade competitive antagonist of group I and II metabotropic glutamate receptors (mGluRs). It is supplied as a white to off-white solid and is used in neuroscience studies to inhibit mGluR-mediated signaling and to investigate synaptic plasticity mechanisms such as theta-burst stimulation-induced shifts in hippocampal neurons.
- Competitive antagonist of group I and II metabotropic glutamate receptors.
- Useful for blocking theta-burst stimulation-induced synaptic changes in rodent hippocampal preparations.
- White to off-white solid suitable for in vitro and ex vivo assays.
- High purity: 99.1%.
- Molecular weight 209.20 g·mol⁻¹; formula C10H11NO4; CAS 146669-29-6.
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Medchemexpress LLC Topramezone | 210631-68-8 | 100.0% | 363.39 g/mol | C16H17N3O5S | 5 MG
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Topramezone (Standard) is an analytical reference standard of topramezone, a 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor and post-emergence herbicide used for control of broadleaf and grass weeds in corn. Supplied for research and analytical applications, it is intended for qualitative and quantitative methods in HPLC, GC, and MS. CAS 210631-68-8; formula C16H17N3O5S; molecular weight 363.39 g/mol.
- Intended for analytical and research use in HPLC, GC, and MS.
- Potent 4-HPPD inhibitor used as a herbicide reference standard.
- Characterized by CAS 210631-68-8 and defined molecular formula and weight.
- Provided as an analytical-grade standard with high purity for quantitative assays.
- Suitable as a reference material for method development and validation.
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eMolecules 32085-88-4 | 3,5-Difluorobenzaldehyde | Apollo Scientific US - Building Blocks | MFCD00010329 | 142.105 | C7H4F2O | 98.000 | Fc1cc(F)cc(C=O)c1 | 25g | 398008395
3,5-Difluorobenzaldehyde | Apollo Scientific US - Building Blocks | 32085-88-4 | MFCD00010329 | 142.105 | C7H4F2O | 98.000 | Fc1cc(F)cc(C=O)c1 | 25g | 398008395
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![Medchemexpress LLC 5-nitro-2-{[5-(phenoxymethyl)-4-phenyl-4H-1,2,4-triazol-3-yl]thio}pyridine | 345989-24-4 | 99.9% | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000232386.png-250.jpg)
Medchemexpress LLC 5-nitro-2-{[5-(phenoxymethyl)-4-phenyl-4H-1,2,4-triazol-3-yl]thio}pyridine | 345989-24-4 | 99.9% | 25 MG
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MIND4-17 is a small-molecule NRF2 activator that covalently modifies the C151 residue of Keap1, disrupting Keap1-Nrf2 association and stabilizing Nrf2 to induce antioxidant response element (ARE) gene expression. Supplied as a solid with high reported purity, it is used in cellular and in vivo studies of oxidative stress pathways.
- Activates Nrf2 signaling by modifying Keap1 C151.
- Promotes expression of ARE-regulated antioxidant genes such as Nqo1 and Hmox1.
- Reported molecular weight 405.43 g/mol and formula C20H15N5O3S.
- Purity reported as 99.93% on the product page.
- Supplied as an off-white to light yellow solid in multiple sizes, including 25 mg.
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Medchemexpress LLC (S)-Purvalanol B | >=98.0% | 5 MG
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Purvalanol B (NG 95) is a potent, selective, reversible, and ATP-competitive inhibitor of CDK. It inhibits the growth of a chloroquine-resistant strain of P. falciparum.
- Potent, selective, reversible, and ATP-competitive inhibitor of CDK
- Inhibits cdc2-cyclin B, CDK2-cyclin A, CDK5-p35, and CDK2-cyclin E
- Selective for CDK over other protein kinases
- Inhibits growth of chloroquine-resistant P. falciparum
- Inhibitory activity against Cyclin-dependent kinase 1-cyclin B complex from starfish oocytes
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Medchemexpress LLC Ampk-in-3 | 2417674-27-0 | C25H33N5O3 | 10 MM 1 ML
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AMPK-IN-3 is a potent and selective AMPK inhibitor with IC50s of 60.7 nM for AMPK (α2) and 107 nM for AMPK (α1). It is described as a yellow to brown solid, and it inhibits AMPK without affecting cell viability or causing significant cytotoxicity in K562 cells. This compound can be used in the study of cancer.
- Potent and selective inhibitor of AMPK
- Does not affect cell viability
- Does not cause significant cytotoxicity in K562 cells
- Useful in cancer research
- Solid appearance, yellow to brown color
- Soluble in DMSO
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Medchemexpress LLC Cinnarizine | 298-57-7 | MFCD00056037 | 99.6% | 1 ML
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Cinnarizine | 298-57-7 | MFCD00056037 | 99.6% | 1 ML
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LIFE TECHNOLOGIES
QGP302 MULTIPLEX 2PLEX 10PLATE
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Medchemexpress LLC Autoinducing Peptide I | 200010-29-3 | 99.25% | 961.11 | 5 MG
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Autoinducing Peptide I (AIP-I) is a cyclic octapeptide secreted by *Staphylococcus aureus*. This peptide is utilized in vaccine research applications.
- Cyclic octapeptide
- Secreted by *Staphylococcus aureus*
- Used in vaccine research
- For research use only
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Cayman Chemical CAY10565 Neurochemicals
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A S-nitrosothiol that acts as an NO donor under acidic conditions; decomposes with a half-life of 130 minutes in 0.1 M phosphate buffer, pH 5.0, at 37°C; relaxes phenylephrine-constricted rat aortic strips 71% and 44% at pH 6.0 and 7.4, respectively
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